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Results: 1-16 |
Results: 16
INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS - SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF NOVEL SERIES OF SULFONAMIDES, ACYLPHOSPHONAMIDES AND ACYLPHOSPHORAMIDATES
Authors: LEE HT ROARK WH PICARD JA SLISKOVIC DR ROTH BD STANFIELD RL HAMELEHLE KL BOUSLEY RF KRAUSE BR
Citation: Ht. Lee et al., INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS - SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF NOVEL SERIES OF SULFONAMIDES, ACYLPHOSPHONAMIDES AND ACYLPHOSPHORAMIDATES, Bioorganic & medicinal chemistry letters, 8(3), 1998, pp. 289-294
ALPHA-SUBSTITUTED MALONESTER AMIDES - TOOLS TO DEFINE THE RELATIONSHIP BETWEEN ACAT INHIBITION AND ADRENAL TOXICITY
Authors: SLISKOVIC DR PICARD JA OBRIEN PM LIAO P ROARK WH ROTH BD ANDERSON MA MUELLER SB BOCAN TMA BOUSLEY RF HAMELEHLE KL HOMAN R REINDEL JF STANFIELD RL TURLUCK D KRAUSE BR
Citation: Dr. Sliskovic et al., ALPHA-SUBSTITUTED MALONESTER AMIDES - TOOLS TO DEFINE THE RELATIONSHIP BETWEEN ACAT INHIBITION AND ADRENAL TOXICITY, Journal of medicinal chemistry, 41(5), 1998, pp. 682-690
CI-1011 LOWERS LIPOPROTEIN(A) AND PLASMA-CHOLESTEROL CONCENTRATIONS IN CHOW-FED CYNOMOLGUS MONKEYS
Authors: RAMHARACK R SPAHR MA SEKERKE CS STANFIELD RL BOUSLEY RF LEE HT KRAUSE BK
Citation: R. Ramharack et al., CI-1011 LOWERS LIPOPROTEIN(A) AND PLASMA-CHOLESTEROL CONCENTRATIONS IN CHOW-FED CYNOMOLGUS MONKEYS, Atherosclerosis, 136(1), 1998, pp. 79-87
TETRAZOLE-SUBSTITUTED UREAS AS INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE (ACAT) - A NOVEL PREPARATION OF UREAS FROM WEAKLY NUCLEOPHILIC AMINES
Authors: PURCHASE CF WHITE AD ANDERSON MK BOCAN TMA BOUSLEY RF HAMELEHLE KL HOMAN R KRAUSE BR LEE P MUELLER SB SPEYER C STANFIELD RL REINDEL JF
Citation: Cf. Purchase et al., TETRAZOLE-SUBSTITUTED UREAS AS INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE (ACAT) - A NOVEL PREPARATION OF UREAS FROM WEAKLY NUCLEOPHILIC AMINES, Bioorganic & medicinal chemistry letters, 6(15), 1996, pp. 1753-1758
INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE .17. STRUCTURE-ACTIVITY-RELATIONSHIPS OF SEVERAL SERIES OF COMPOUNDS DERIVED FROM N-CHLOROSULFONYL ISOCYANATE
Authors: PICARD JA OBRIEN PM SLISKOVIC DR ANDERSON MK BOUSLEY RF HAMELEHLE KL KRAUSE BR STANFIELD RL
Citation: Ja. Picard et al., INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE .17. STRUCTURE-ACTIVITY-RELATIONSHIPS OF SEVERAL SERIES OF COMPOUNDS DERIVED FROM N-CHLOROSULFONYL ISOCYANATE, Journal of medicinal chemistry, 39(6), 1996, pp. 1243-1252
INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS - CI-1011 - AN ACYL SULFAMATE WITH UNIQUE CHOLESTEROL-LOWERING ACTIVITY IN ANIMALS FED NONCHOLESTEROL-SUPPLEMENTED DIETS
Authors: LEE HT SLISKOVIC DR PICARD JA ROTH BD WIERENGA W HICKS JL BOUSLEY RF HAMELEHLE KL HOMAN R SPEYER C STANFIELD RL KRAUSE BR
Citation: Ht. Lee et al., INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS - CI-1011 - AN ACYL SULFAMATE WITH UNIQUE CHOLESTEROL-LOWERING ACTIVITY IN ANIMALS FED NONCHOLESTEROL-SUPPLEMENTED DIETS, Journal of medicinal chemistry, 39(26), 1996, pp. 5031-5034
HETEROCYCLIC UREAS - INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE AS HYPOCHOLESTEROLEMIC AGENTS
Authors: WHITE AD CRESWELL MW CHUCHOLOWSKI AW BLANKLEY CJ WILSON MW BOUSLEY RF ESSENBURG AD HAMELEHLE KL KRAUSE BR STANFIELD RL DOMINICK MA NEUB M
Citation: Ad. White et al., HETEROCYCLIC UREAS - INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE AS HYPOCHOLESTEROLEMIC AGENTS, Journal of medicinal chemistry, 39(22), 1996, pp. 4382-4395
HETEROCYCLIC AMIDES - INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE WITH HYPOCHOLESTEROLEMIC ACTIVITY IN SEVERAL SPECIES AND ANTIATHEROSCLEROTIC ACTIVITY IN THE RABBIT
Authors: WHITE AD PURCHASE CF PICARD JA ANDERSON MK MUELLER SB BOCAN TMA BOUSLEY RF HAMELEHLE KL KRAUSE BR LEE P STANFIELD RL REINDEL JF
Citation: Ad. White et al., HETEROCYCLIC AMIDES - INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE WITH HYPOCHOLESTEROLEMIC ACTIVITY IN SEVERAL SPECIES AND ANTIATHEROSCLEROTIC ACTIVITY IN THE RABBIT, Journal of medicinal chemistry, 39(20), 1996, pp. 3908-3919
INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS .12. SYNTHESES AND BIOLOGICAL-ACTIVITY OF STRUCTURALLY NOVEL TETRAZOLE AMIDES
Authors: OBRIEN PM SLISKOVIC DR ANDERSON MK BOUSLEY RF KRAUSE BR STANFIELD RL
Citation: Pm. Obrien et al., INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS .12. SYNTHESES AND BIOLOGICAL-ACTIVITY OF STRUCTURALLY NOVEL TETRAZOLE AMIDES, Bioorganic & medicinal chemistry letters, 5(3), 1995, pp. 289-294
INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS .13. DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATIONOF TETRAZOLE ANILIDES AS POTENT INHIBITORS OF ACAT IN-VITRO AND HYPOCHOLESTEROLEMIC AGENTS IN-VITRO
Authors: OBRIEN PM SLISKOVIC DR BERNABEI A HURLEY T ANDERSON MK BOUSLEY RF KRAUSE BR STANFIELD RL
Citation: Pm. Obrien et al., INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS .13. DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATIONOF TETRAZOLE ANILIDES AS POTENT INHIBITORS OF ACAT IN-VITRO AND HYPOCHOLESTEROLEMIC AGENTS IN-VITRO, Bioorganic & medicinal chemistry letters, 5(3), 1995, pp. 295-300
INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS .14. SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF A NOVEL SERIES OF SULFONAMIDE TETRAZOLES
Authors: LEE HT SLISKOVIC DR STANFIELD RL HAMELEHLE KL BOUSLEY RF KRAUSE BR
Citation: Ht. Lee et al., INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS .14. SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF A NOVEL SERIES OF SULFONAMIDE TETRAZOLES, Bioorganic & medicinal chemistry letters, 5(3), 1995, pp. 301-306
INHIBITORS OF ACYL-COA-CHOLESTEROL ACYLTRANSFERASE (ACAT) .15. SULFONYLUREA INHIBITORS WITH EXCELLENT HYPOCHOLESTEROLEMIC ACTIVITY IN-VIVO
Authors: ROTH BD ROARK WH PICARD JA STANFIELD RL BOUSLEY RF ANDERSON MK HAMELEHLE KL HOMAN R KRAUSE BR
Citation: Bd. Roth et al., INHIBITORS OF ACYL-COA-CHOLESTEROL ACYLTRANSFERASE (ACAT) .15. SULFONYLUREA INHIBITORS WITH EXCELLENT HYPOCHOLESTEROLEMIC ACTIVITY IN-VIVO, Bioorganic & medicinal chemistry letters, 5(20), 1995, pp. 2367-2370
INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS .6. THE FIRST WATER-SOLUBLE ACAT INHIBITOR WITH LIPID-REGULATING ACTIVITY
Authors: SLISKOVIC DR KRAUSE BR PICARD JA ANDERSON M BOUSLEY RF HAMELEHLE KL HOMAN R JULIAN TN RASHIDBAIGI ZA STANFIELD RL
Citation: Dr. Sliskovic et al., INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS .6. THE FIRST WATER-SOLUBLE ACAT INHIBITOR WITH LIPID-REGULATING ACTIVITY, Journal of medicinal chemistry, 37(5), 1994, pp. 560-562
INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE .11. STRUCTURE-ACTIVITY-RELATIONSHIPS OF SEVERAL SERIES OF COMPOUNDS DERIVED FROM N-(CHLOROCARBONYL) ISOCYANATE
Authors: PICARD JA BOUSLEY RF LEE HT HAMELEHLE KL KRAUSE BR MINTON LL SLISKOVIC DR STANFIELD RL
Citation: Ja. Picard et al., INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE .11. STRUCTURE-ACTIVITY-RELATIONSHIPS OF SEVERAL SERIES OF COMPOUNDS DERIVED FROM N-(CHLOROCARBONYL) ISOCYANATE, Journal of medicinal chemistry, 37(15), 1994, pp. 2394-2400
INHIBITORS OF ACYL-COA-CHOLESTEROL ACYLTRANSFERASE (ACAT) .7. DEVELOPMENT OF A SERIES OF SUBSTITUTED N-PHENYL-N'-[(1-PHENYLCYCLOPENTYL)METHYL]UREAS WITH ENHANCED HYPOCHOLESTEROLEMIC ACTIVITY
Authors: TRIVEDI BK PURCHASE TS HOLMES A AUGELLISZAFRAN CE ESSENBURG AD HAMELEHLE KL STANFIELD RL BOUSLEY RF KRAUSE BR
Citation: Bk. Trivedi et al., INHIBITORS OF ACYL-COA-CHOLESTEROL ACYLTRANSFERASE (ACAT) .7. DEVELOPMENT OF A SERIES OF SUBSTITUTED N-PHENYL-N'-[(1-PHENYLCYCLOPENTYL)METHYL]UREAS WITH ENHANCED HYPOCHOLESTEROLEMIC ACTIVITY, Journal of medicinal chemistry, 37(11), 1994, pp. 1652-1659
INHIBITORS OF ACYL-COA CHOLESTEROL ACYLTRANSFERASE .5. IDENTIFICATIONAND STRUCTURE-ACTIVITY-RELATIONSHIPS OF NOVEL BETA-KETOAMIDES AS HYPOCHOLESTEROLEMIC AGENTS
Authors: AUGELLISZAFRAN CE BLANKLEY CJ ROTH BD TRIVEDI BK BOUSLEY RF ESSENBURG AD HAMELEHLE KL KRAUSE BR STANFIELD RL
Citation: Ce. Augelliszafran et al., INHIBITORS OF ACYL-COA CHOLESTEROL ACYLTRANSFERASE .5. IDENTIFICATIONAND STRUCTURE-ACTIVITY-RELATIONSHIPS OF NOVEL BETA-KETOAMIDES AS HYPOCHOLESTEROLEMIC AGENTS, Journal of medicinal chemistry, 36(20), 1993, pp. 2943-2949
Risultati: 1-16 |