Authors:
Gaillard, PJ
van der Meide, PH
de Boer, AG
Breimer, DD
Citation: Pj. Gaillard et al., Glucocorticoid and type I interferon interactions at the blood-brain barrier: relevance for drug therapies for multiple sclerosis, NEUROREPORT, 12(10), 2001, pp. 2189-2193
Authors:
van der Sandt, ICJ
Smolders, R
Nabulsi, L
Zuideveld, KP
de Boer, AG
Breimer, DD
Citation: Icj. Van Der Sandt et al., Active efflux of the 5-HT1A receptor agonist flesinoxan via P-glycoproteinat the blood-brain barrier, EUR J PH SC, 14(1), 2001, pp. 81-86
Authors:
Gaillard, PJ
Voorwinden, LH
Nielsen, JL
Ivanov, A
Atsumi, R
Engman, H
Ringbom, C
de Boer, AG
Breimer, DD
Citation: Pj. Gaillard et al., Establishment and functional characterization of an in vitro model of the blood-brain barrier, comprising a co-culture of brain capillary endothelialcells and astrocytes, EUR J PH SC, 12(3), 2001, pp. 215-222
Authors:
van der Sandt, ICJ
Gaillard, PJ
Voorwinden, HH
de Boer, AG
Breimer, DD
Citation: Icj. Van Der Sandt et al., P-glycoprotein inhibition leads to enhanced disruptive effects by anti-microtubule cytostatics at the in vitro blood-brain barrier, PHARM RES, 18(5), 2001, pp. 587-592
Authors:
van der Sandt, ICJ
Vos, CMP
Nabulsi, L
Blom-Roosemalen, MCM
Voorwinden, HH
de Boer, AG
Breimer, DD
Citation: Icj. Van Der Sandt et al., Assessment of active transport of HIV protease inhibitors in various cell lines and the in vitro blood-brain barrier, AIDS, 15(4), 2001, pp. 483-491
Authors:
van der Sandt, ICJ
Blom-Roosemalen, MCM
de Boer, AG
Breimer, DD
Citation: Icj. Van Der Sandt et al., Specificity of doxorubicin versus rhodamine-123 in assessing P-glycoprotein functionality in the LLC-PK1, LLC-PK1 : MDR1 and Caco-2 cell lines, EUR J PH SC, 11(3), 2000, pp. 207-214
Authors:
Gaillard, PJ
van der Sandt, ICJ
Voorwinden, LH
Vu, D
Nielsen, JL
de Boer, AG
Breimer, DD
Citation: Pj. Gaillard et al., Astrocytes increase the functional expression of P-glycoprotein in an in vitro model of the blood-brain barrier, PHARM RES, 17(10), 2000, pp. 1198-1205
Citation: Dd. Breimer, An interview with a distinguished pharmaceutical scientist - Douwe D. Breimer - Elected foreign associate member of the Institute of Medicine of the National Academy of Sciences of the USA (1999), PHARM RES, 17(1), 2000, pp. 1-6
Authors:
Pereira, VA
Auler, JO
Carmona, MJ
Mateus, FH
Lanchote, VL
Breimer, DD
Santos, SRCJ
Citation: Va. Pereira et al., A micromethod for quantitation of debrisoquine and 4-hydroxydebrisoquine in urine by liquid chromatography, BRAZ J MED, 33(5), 2000, pp. 509-514
Authors:
Wijnholds, J
de Lange, ECM
Scheffer, GL
van den Berg, DJ
Mol, CAAM
van der Valk, M
Schinkel, AH
Scheper, RJ
Breimer, DD
Borst, P
Citation: J. Wijnholds et al., Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier, J CLIN INV, 105(3), 2000, pp. 279-285
Authors:
de Boer, AG
de Lange, ECM
van der Sandt, ICJ
Breimer, DD
Citation: Ag. De Boer et al., The application of microdialysis techniques to the study of drug transportacross the blood-brain barrier, BLOOD-BRAIN BARRIER AND DRUG DELIVERY TO THE CNS, 2000, pp. 77-92
Authors:
Hesselink, MB
Smolders, H
De Boer, AG
Breimer, DD
Danysz, W
Citation: Mb. Hesselink et al., Modifications of the behavioral profile of non-competitive NMDA receptor antagonists, memantine, amantadine and (+)MK-801 after chronic administration, BEHAV PHARM, 10(1), 1999, pp. 85-98
Authors:
Hesselink, MB
De Boer, BG
Breimer, DD
Danysz, W
Citation: Mb. Hesselink et al., Brain penetration and in vivo recovery of NMDA receptor antagonists amantadine and memantine: A quantitative microdialysis study, PHARM RES, 16(5), 1999, pp. 637-642
Authors:
Hesselink, MB
De Boer, AG
Breimer, DD
Danysz, W
Citation: Mb. Hesselink et al., Dopamine release in the prefrontal cortex in response to memantine following sub-chronic NMDA receptor blockade with memantine: a microdialysis studyin rats, J NEURAL TR, 106(9-10), 1999, pp. 803-818
Authors:
Hesselink, MB
De Boer, AG
Breimer, DD
Danysz, W
Citation: Mb. Hesselink et al., Adaptations of NMDA and dopamine D-2, but not of muscarinic receptors following 14 days administration of uncompetitive NMDA receptor antagonists, J NEURAL TR, 106(5-6), 1999, pp. 409-421
Authors:
van Steveninck, AL
van Berckel, BNM
Schoemaker, RC
Breimer, DD
van Gerven, JMA
Cohen, AF
Citation: Al. Van Steveninck et al., The sensitivity of pharmacodynamic tests for the central nervous system effects of drugs on the effects of sleep deprivation, J PSYCHOPH, 13(1), 1999, pp. 10-17
Authors:
Hesselink, MB
Smolders, H
Eilbacher, B
De Boer, AG
Breimer, DD
Danysz, W
Citation: Mb. Hesselink et al., The role of probenecid-sensitive organic acid transport in the pharmacokinetics of N-methyl-D-aspartate receptor antagonists acting at the glycine(B)-site: Microdialysis and maximum electroshock seizures studies, J PHARM EXP, 290(2), 1999, pp. 543-550