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Results:
1-17
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Results: 17
Authors:
Shaw, KTY
Utsuki, T
Rogers, J
Yu, QS
Sambamurti, K
Brossi, A
Ge, YW
Lahiri, DK
Greig, NH
Citation: Kty. Shaw et al., Phenserine regulates translation of beta-amyloid precursor protein mRNA bya putative interleukin-1 responsive element, a target for drug development, P NAS US, 98(13), 2001, pp. 7605-7610
Authors:
Yu, QS
Holloway, HW
Flippen-Anderson, JL
Hoffman, B
Brossi, A
Greig, NH
Citation: Qs. Yu et al., Methyl analogues of the experimental Alzheimer drug phenserine: Synthesis and structure/activity relationships for acetyl- and butyrylcholinesterase inhibitory action, J MED CHEM, 44(24), 2001, pp. 4062-4071
Authors:
Yu, QS
Greig, NH
Holloway, HW
Flippen-Anderson, JL
Brossi, A
Citation: Qs. Yu et al., (-)-(3aS)-eseroline carbamate (II), a potent cholinesterase inhibitor and close analogue of physostigmine: Reanalysis, MED CHEM RE, 10(3), 2000, pp. 186-199
Authors:
Yang, ZY
Xia, Y
Xia, P
Brossi, A
Cosentino, LM
Lee, KH
Citation: Zy. Yang et al., Anti-AIDS agents part 41: Synthesis and anti-HIV activity of 3 ',4 '-di-o-(-)-camphanoyl-(+)-cis-khellactone (DCK) lactam analogues, BIOORG MED, 10(10), 2000, pp. 1003-1005
Authors:
Zhu, XX
Greig, NH
Holloway, HW
Whittaker, NF
Brossi, A
Yu, QS
Citation: Xx. Zhu et al., A practical conversion of natural physostigmine into the potent butyrylcholinesterase inhibitor N-1,N-8-bisnorcymserine, TETRAHEDR L, 41(25), 2000, pp. 4861-4864
Authors:
Zhang, SX
Feng, J
Kuo, SC
Brossi, A
Hamel, E
Tropsha, A
Li, KH
Citation: Sx. Zhang et al., Antitumor agents. 199. Three-dimensional quantitative structure-activity relationship study of the colchicine binding site ligands using comparative molecular field analysis, J MED CHEM, 43(2), 2000, pp. 167-176
Authors:
Bai, RL
Covell, DG
Pei, XF
Ewell, JB
Nguyen, NY
Brossi, A
Hamel, E
Citation: Rl. Bai et al., Mapping the binding site of colchicinoids on beta-tubulin - 2-chloroacetyl-2-demethylthiocolchicine covalently reacts predominantly with cysteine 239and secondarily with cysteine 354, J BIOL CHEM, 275(51), 2000, pp. 40443-40452
Authors:
Greig, NH
De Micheli, E
Holloway, HW
Yu, QS
Utsuki, T
Perry, TA
Brossi, A
Ingram, DK
Deutsch, J
Lahiri, DK
Soncrant, TT
Citation: Nh. Greig et al., The experimental Alzheimer drug phenserine: preclinical pharmacokinetics and pharmacodynamics, ACT NEUR SC, 102, 2000, pp. 74-84
Authors:
Xia, Y
Yang, ZY
Brossi, A
Lee, KH
Citation: Y. Xia et al., Asymmetric solid-phase synthesis of (3 ' R,4 ' R)-Di-O-cis-acyl 3-carboxylkhellactones, ORG LETT, 1(13), 1999, pp. 2113-2115
Authors:
Pei, XF
Yu, QS
Holloway, HW
Brossi, A
Greig, NH
Citation: Xf. Pei et al., Syntheses and biological evaluation of ring-C opened analogues of the cholinesterase inhibitors physostigmine, phenserine and cymserine, MED CHEM RE, 9(1), 1999, pp. 50-60
Authors:
Yu, QS
Greig, NH
Holloway, HW
Brossi, A
Citation: Qs. Yu et al., 4 '-hydroxyphenylcarbamates of (3aS)-eseroline and (3aS)-N(1)-noreseroline: Potential metabolites of the Alzheimer's anticholinesterase drug phenserine, HETEROCYCLE, 50(1), 1999, pp. 95-102
Authors:
Yang, ZY
Xia, Y
Xia, P
Brossi, A
Lee, KH
Citation: Zy. Yang et al., A concise regiospecific synthesis of 8,8-dimethyl-2H,8H-pyrano [6,5-h]quinolin-2-one and related compounds, TETRAHEDR L, 40(24), 1999, pp. 4505-4506
Authors:
Yu, QS
Holloway, HW
Utsuki, T
Brossi, A
Greig, NH
Citation: Qs. Yu et al., Synthesis of novel phenserine-based-selective inhibitors of butyrylcholinesterase for Alzheimer's disease, J MED CHEM, 42(10), 1999, pp. 1855-1861
Authors:
Brossi, A
Lee, HH
Yeh, HJC
Citation: A. Brossi et al., Axial configuration of optically active colchicinoids and allocolchicinoids: A correction, HELV CHIM A, 82(8), 1999, pp. 1223-1224
Authors:
Guan, J
Zhu, XK
Brossi, A
Tachibana, Y
Bastow, KF
Verdier-Pinard, P
Hamel, E
McPhail, AT
Lee, KH
Citation: J. Guan et al., Antitumor agents. 192. Antitubulin effect and cytotoxicity of C(7)-oxygenated allocolchicinoids, COLL CZECH, 64(2), 1999, pp. 217-228
Authors:
Guan, J
Zhu, XK
Tachibana, Y
Bastow, KF
Brossi, A
Hamel, E
Lee, KH
Citation: J. Guan et al., Antitumor agents. Part 186: Synthesis and biological evaluation of demethylcolchiceinamide analogues as cytotoxic DNA topoisomerase II inhibitors, BIO MED CH, 6(11), 1998, pp. 2127-2131
Authors:
Pei, XF
Greig, NH
Brossi, A
Citation: Xf. Pei et al., Syntheses and biological evaluation of (+/-)-3a-phenyl congeners of physostigmine and phenserine, HETEROCYCLE, 49, 1998, pp. 437-444
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