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Results: 1-11 |
Results: 11
AN INHIBITOR OF LEUKOCYTE ELASTASE PREVENTS IMMUNE COMPLEX-MEDIATED HEMORRHAGE IN THE RAT LUNG
Authors: FLETCHER DS OSINGA DG KEENAN K BONNEY RJ DOHERTY JB FINKE PE SHAH SK DAVIES P
Citation: Ds. Fletcher et al., AN INHIBITOR OF LEUKOCYTE ELASTASE PREVENTS IMMUNE COMPLEX-MEDIATED HEMORRHAGE IN THE RAT LUNG, The Journal of pharmacology and experimental therapeutics, 274(1), 1995, pp. 548-554
ORALLY-ACTIVE BETA-LACTAM INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE .3. STEREOSPECIFIC SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS FOR 3,3-DIALKYLAZETIDIN-2-ONES
Authors: FINKE PE SHAH SK FLETCHER DS ASHE BM BRAUSE KA CHANDLER GO DELLEA PS HAND KM MAYCOCK AL OSINGA DG UNDERWOOD DJ WESTON H DAVIES P DOHERTY JB
Citation: Pe. Finke et al., ORALLY-ACTIVE BETA-LACTAM INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE .3. STEREOSPECIFIC SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS FOR 3,3-DIALKYLAZETIDIN-2-ONES, Journal of medicinal chemistry, 38(13), 1995, pp. 2449-2462
MECHANISM OF INHIBITION OF HUMAN-LEUKOCYTE ELASTASE BY BETA-LACTAMS .2. STABILITY, REACTIVATION KINETICS, AND PRODUCTS OF BETA-LACTAM-DERIVED E-I COMPLEXES
Authors: GREEN BG CHABIN R MILLS S UNDERWOOD DJ SHAH SK KUO D GALE P MAYCOCK AL LIESCH J BURGEY CS DOHERTY JB DORN CP FINKE PE HAGMANN WK HALE JJ MACCOSS M WESTLER WM KNIGHT WB
Citation: Bg. Green et al., MECHANISM OF INHIBITION OF HUMAN-LEUKOCYTE ELASTASE BY BETA-LACTAMS .2. STABILITY, REACTIVATION KINETICS, AND PRODUCTS OF BETA-LACTAM-DERIVED E-I COMPLEXES, Biochemistry, 34(44), 1995, pp. 14331-14343
MECHANISM OF INHIBITION OF HUMAN-LEUKOCYTE ELASTASE BY BETA-LACTAMS .3. USE OF ELECTROSPRAY-IONIZATION MASS-SPECTROMETRY AND 2-DIMENSIONAL NMR TECHNIQUES TO IDENTIFY BETA-LACTAM-DERIVED E-I-COMPLEXES
Authors: UNDERWOOD DJ GREEN BG CHABIN R MILLS S DOHERTY JB FINKE PE MACCOSS M SHAH SK BURGEY CS DICKINSON TA GRIFFIN PR LEE TE SWIDEREK KM COVEY T WESTLER WM KNIGHT WB
Citation: Dj. Underwood et al., MECHANISM OF INHIBITION OF HUMAN-LEUKOCYTE ELASTASE BY BETA-LACTAMS .3. USE OF ELECTROSPRAY-IONIZATION MASS-SPECTROMETRY AND 2-DIMENSIONAL NMR TECHNIQUES TO IDENTIFY BETA-LACTAM-DERIVED E-I-COMPLEXES, Biochemistry, 34(44), 1995, pp. 14344-14355
INHIBITION OF HUMAN-LEUKOCYTE ELASTASE .5. INHIBITION BY 6-ALKYL SUBSTITUTED PENEM BENZYL-ESTERS
Authors: FINKE PE DAHLGREN ME WESTON H MAYCOCK AL DOHERTY JB
Citation: Pe. Finke et al., INHIBITION OF HUMAN-LEUKOCYTE ELASTASE .5. INHIBITION BY 6-ALKYL SUBSTITUTED PENEM BENZYL-ESTERS, Bioorganic & medicinal chemistry letters, 3(11), 1993, pp. 2277-2282
INHIBITION OF HUMAN-LEUKOCYTE ELASTASE .6. INHIBITION BY 6-SUBSTITUTED PENICILLIN ESTERS
Authors: THOMPSON KR FINKE PE SHAH SK ASHE BM DAHLGREN ME MAYCOCK AL DOHERTY JB
Citation: Kr. Thompson et al., INHIBITION OF HUMAN-LEUKOCYTE ELASTASE .6. INHIBITION BY 6-SUBSTITUTED PENICILLIN ESTERS, Bioorganic & medicinal chemistry letters, 3(11), 1993, pp. 2283-2288
INHIBITION OF HUMAN-LEUKOCYTE ELASTASE .7. INHIBITION BY 6-SUBSTITUTED PENICILLIN AMIDES
Authors: THOMPSON KR FINKE PE SHAH SK ASHE BM DAHLGREN ME DELLEA PS FLETCHER DS HAND KM MAYCOCK AL DOHERTY JB
Citation: Kr. Thompson et al., INHIBITION OF HUMAN-LEUKOCYTE ELASTASE .7. INHIBITION BY 6-SUBSTITUTED PENICILLIN AMIDES, Bioorganic & medicinal chemistry letters, 3(11), 1993, pp. 2289-2294
MONOCYCLIC BETA-LACTAM INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE - STEREOSPECIFIC SYNTHESIS AND ACTIVITY OF 3,4-DISUBSTITUTED-2-AZETIDINONES
Authors: SHAH SK FINKE PE BRAUSE KA CHANDLER GO ASHE BM WESTON H MAYCOCK AL MUMFORD RA DOHERTY JB
Citation: Sk. Shah et al., MONOCYCLIC BETA-LACTAM INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE - STEREOSPECIFIC SYNTHESIS AND ACTIVITY OF 3,4-DISUBSTITUTED-2-AZETIDINONES, Bioorganic & medicinal chemistry letters, 3(11), 1993, pp. 2295-2298
CHEMICAL, BIOCHEMICAL, PHARMACOKINETIC, AND BIOLOGICAL PROPERTIES OF L-680,833 - A POTENT, ORALLY-ACTIVE MONOCYCLIC BETA-LACTAM INHIBITOR OF HUMAN POLYMORPHONUCLEAR LEUKOCYTE ELASTASE
Authors: DOHERTY JB SHAH SK FINKE PE DORN CP HAGMANN WK HALE JJ KISSINGER AL THOMPSON KR BRAUSE K CHANDLER GO KNIGHT WB MAYCOCK AL AHSE BM WESTON H GALE P MUMFORD RA ANDERSEN OF WILLIAMS HR NOLAN TE FRANKENFIELD DL UNDERWOOD D VYAS KP KARI PH DAHLGREN ME MAO J FLETCHER DS DELLEA PS HAND KM OSINGA DG PETERSON LB WILLIAMS DT METZGER JM BONNEY RJ HUMES JL PACHOLOK SP HANLON WA OPAS E STOLK J DAVIES P
Citation: Jb. Doherty et al., CHEMICAL, BIOCHEMICAL, PHARMACOKINETIC, AND BIOLOGICAL PROPERTIES OF L-680,833 - A POTENT, ORALLY-ACTIVE MONOCYCLIC BETA-LACTAM INHIBITOR OF HUMAN POLYMORPHONUCLEAR LEUKOCYTE ELASTASE, Proceedings of the National Academy of Sciences of the United Statesof America, 90(18), 1993, pp. 8727-8731
MECHANISM OF INHIBITION OF HUMAN-LEUKOCYTE ELASTASE BY MONOCYCLIC BETA-LACTAMS
Authors: CHABIN R GREEN BG GALE P MAYCOCK AL WESTON H DORN CP FINKE PE HAGMANN WK HALE JJ MACCOSS M SHAH SK UNDERWOOD D DOHERTY JB KNIGHT WB
Citation: R. Chabin et al., MECHANISM OF INHIBITION OF HUMAN-LEUKOCYTE ELASTASE BY MONOCYCLIC BETA-LACTAMS, Biochemistry, 32(34), 1993, pp. 8970-8980
A SPECIFIC MECHANISM-BASED ASSAY OF PMN ELASTASE-MONOCYCLIC-BETA-LACTAM INHIBITOR COMPLEXES IN BIOLOGIC MILIEUS
Authors: HUMES JL CHABIN R DAVIES P DOHERTY JB FINKE P FLETCHER D GREEN B GRIFFIN PR HANLON WA KNIGHT WB MACCOSS M PACHOLOK SG SHAH S MUMFORD RA
Citation: Jl. Humes et al., A SPECIFIC MECHANISM-BASED ASSAY OF PMN ELASTASE-MONOCYCLIC-BETA-LACTAM INHIBITOR COMPLEXES IN BIOLOGIC MILIEUS, The American review of respiratory disease, 147(4), 1993, pp. 677-677
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