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Results: 1-18 |
Results: 18
2,2'-DITHIOBISBENZAMIDES DERIVED FROM ALPHA-AMINO-ACIDS, BETA-AMINO-ACIDS AND GAMMA-AMINO-ACIDS POSSESSING ANTI-HIV ACTIVITIES - SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONSHIP
Authors: PRASAD JVNV LOO JA BOYER FE STIER MA GOGLIOTTI RD TURNER WJ HARVEY PJ KRAMER MR MACK DP SCHOLTEN JD GRACHECK SJ DOMAGALA JM
Citation: Jvnv. Prasad et al., 2,2'-DITHIOBISBENZAMIDES DERIVED FROM ALPHA-AMINO-ACIDS, BETA-AMINO-ACIDS AND GAMMA-AMINO-ACIDS POSSESSING ANTI-HIV ACTIVITIES - SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONSHIP, Bioorganic & medicinal chemistry, 6(10), 1998, pp. 1707-1730
A NEW CLASS OF ANTI-HIV-1 AGENTS TARGETED TOWARD THE NUCLEOCAPSID PROTEIN NCP7 - THE 2,2'-DITHIOBISBENZAMIDES
Authors: DOMAGALA JM BADER JP GOGLIOTTI RD SANCHEZ JP STIER MA SONG YT PRASAD JVNV TUMMINO PJ SCHOLTEN J HARVEY P HOLLER T GRACHECK S HUPE D RICE WG SCHULTZ R
Citation: Jm. Domagala et al., A NEW CLASS OF ANTI-HIV-1 AGENTS TARGETED TOWARD THE NUCLEOCAPSID PROTEIN NCP7 - THE 2,2'-DITHIOBISBENZAMIDES, Bioorganic & medicinal chemistry, 5(3), 1997, pp. 569-579
SYNTHESIS OF 5,6-DIHYDRO-4-HYDROXY-2-PYRONES AS HIV-1 PROTEASE INHIBITORS - THE PROFOUND EFFECT OF POLARITY ON ANTIVIRAL ACTIVITY
Authors: HAGEN SE PRASAD JVNV BOYER FE DOMAGALA JM ELLSWORTH EL GAJDA C HAMILTON HW MARKOSKI LJ STEINBAUGH BA TAIT BD LUNNEY EA TUMMINO PJ FERGUSON D HUPE D NOUHAN C GRACHECK SJ SAUNDERS JM VANDERROEST S
Citation: Se. Hagen et al., SYNTHESIS OF 5,6-DIHYDRO-4-HYDROXY-2-PYRONES AS HIV-1 PROTEASE INHIBITORS - THE PROFOUND EFFECT OF POLARITY ON ANTIVIRAL ACTIVITY, Journal of medicinal chemistry, 40(23), 1997, pp. 3707-3711
STRUCTURE-ACTIVITY-RELATIONSHIPS OF QUINOLONE AGENTS AGAINST MYCOBACTERIA - EFFECT OF STRUCTURAL MODIFICATIONS AT THE 8-POSITION
Authors: RENAU TE GAGE JW DEVER JA ROLAND GE JOANNIDES ET SHAPIRO MA SANCHEZ JP GRACHECK SJ DOMAGALA JM JACOBS MR REYNOLDS RC
Citation: Te. Renau et al., STRUCTURE-ACTIVITY-RELATIONSHIPS OF QUINOLONE AGENTS AGAINST MYCOBACTERIA - EFFECT OF STRUCTURAL MODIFICATIONS AT THE 8-POSITION, Antimicrobial agents and chemotherapy, 40(10), 1996, pp. 2363-2368
STRUCTURE-ACTIVITY-RELATIONSHIPS OF THE QUINOLONE ANTIBACTERIALS AGAINST MYCOBACTERIA - EFFECT OF STRUCTURAL-CHANGES AT N-1 AND C-7
Authors: RENAU TE SANCHEZ JP GAGE JW DEVER JA SHAPIRO MA GRACHECK SJ DOMAGALA JM
Citation: Te. Renau et al., STRUCTURE-ACTIVITY-RELATIONSHIPS OF THE QUINOLONE ANTIBACTERIALS AGAINST MYCOBACTERIA - EFFECT OF STRUCTURAL-CHANGES AT N-1 AND C-7, Journal of medicinal chemistry, 39(3), 1996, pp. 729-735
THE SYNTHESIS OF 3-BROMO-2,4,5-TRIFLUOROBENZOIC ACID AND ITS CONVERSION TO 8-BROMOQUINOLONECARBOXYLIC ACIDS
Authors: RENAU TE SANCHEZ JP DOMAGALA JM
Citation: Te. Renau et al., THE SYNTHESIS OF 3-BROMO-2,4,5-TRIFLUOROBENZOIC ACID AND ITS CONVERSION TO 8-BROMOQUINOLONECARBOXYLIC ACIDS, Journal of heterocyclic chemistry, 33(4), 1996, pp. 1407-1411
NONPEPTIDIC HIV PROTEASE INHIBITORS - 4-HYDROXY-PYRAN-2-ONE INHIBITORS WITH FUNCTIONAL TETHERS TO P-1 PHENYL RING TO REACH S-3 POCKET OF THE ENZYME
Authors: PRASAD JVNV TUMMINO PJ FERGUSON D SAUNDERS J VANDERROEST S MCQUADE TJ HELDSINGER A REYNER EL STEWART BH GUTTENDORF RJ PARA KS LUNNEY EA GRACHECK SJ DOMAGALA JM
Citation: Jvnv. Prasad et al., NONPEPTIDIC HIV PROTEASE INHIBITORS - 4-HYDROXY-PYRAN-2-ONE INHIBITORS WITH FUNCTIONAL TETHERS TO P-1 PHENYL RING TO REACH S-3 POCKET OF THE ENZYME, Biochemical and biophysical research communications, 221(3), 1996, pp. 815-820
NONPEPTIDIC POTENT HIV-1 PROTEASE INHIBITORS - -HYDROXY-6-PHENYL-2-OXO-2H-PYRAN-3-YL)THIOMETHANES THAT SPAN P-1-P-2' SUBSITES IN A UNIQUE MODE OF ACTIVE-SITE BINDING
Authors: PRASAD JVN PARA KS TUMMINO PJ FERGUSON D MCQUADE TJ LUNNEY EA RAPUNDALO ST BATLEY BL HINGORANI G DOMAGALA JM GRACHECK SJ BHAT TN LIU BS BALDWIN ET ERICKSON JW SAWYER TK
Citation: Jvn. Prasad et al., NONPEPTIDIC POTENT HIV-1 PROTEASE INHIBITORS - -HYDROXY-6-PHENYL-2-OXO-2H-PYRAN-3-YL)THIOMETHANES THAT SPAN P-1-P-2' SUBSITES IN A UNIQUE MODE OF ACTIVE-SITE BINDING, Journal of medicinal chemistry, 38(6), 1995, pp. 898-905
THE SYNTHESIS, STRUCTURE-ACTIVITY, AND STRUCTURE-SIDE EFFECT RELATIONSHIPS OF A SERIES OF 8-ALKOXYQUINOLONE AND 5-AMINO-8-ALKOXYQUINOLONE ANTIBACTERIAL AGENTS
Authors: SANCHEZ JP GOGLIOTTI RD DOMAGALA JM GRACHECK SJ HUBAND MD SESNIE JA COHEN MA SHAPIRO MA
Citation: Jp. Sanchez et al., THE SYNTHESIS, STRUCTURE-ACTIVITY, AND STRUCTURE-SIDE EFFECT RELATIONSHIPS OF A SERIES OF 8-ALKOXYQUINOLONE AND 5-AMINO-8-ALKOXYQUINOLONE ANTIBACTERIAL AGENTS, Journal of medicinal chemistry, 38(22), 1995, pp. 4478-4487
EFFECT OF LIPOPHILICITY AT N-1 ON ACTIVITY OF FLUOROQUINOLONES AGAINST MYCOBACTERIA
Authors: RENAU TE SANCHEZ JP SHAPIRO MA DEVER JA GRACHECK SJ DOMAGALA JM
Citation: Te. Renau et al., EFFECT OF LIPOPHILICITY AT N-1 ON ACTIVITY OF FLUOROQUINOLONES AGAINST MYCOBACTERIA, Journal of medicinal chemistry, 38(15), 1995, pp. 2974-2977
HIV PROTEASE INHIBITORS POSSESSING A NOVEL, HIGH-AFFINITY, AND ACHIRAL P-1' P-2' LIGAND WITH A UNIQUE PATTERN OF IN-VITRO RESISTANCE - IMPORTANCE OF A CONFORMATIONALLY-RESTRICTED TEMPLATE IN THE DESIGN OF ENZYME-INHIBITORS/
Authors: PRASAD JVNV LUNNEY EA FERGUSON D TUMMINO PJ RUBIN JR REYNER EL STEWART BH GUTTENDORF RJ DOMAGALA JM SUVOROV LI GULNIK SV TOPOL IA BHAT TN ERICKSON JW
Citation: Jvnv. Prasad et al., HIV PROTEASE INHIBITORS POSSESSING A NOVEL, HIGH-AFFINITY, AND ACHIRAL P-1' P-2' LIGAND WITH A UNIQUE PATTERN OF IN-VITRO RESISTANCE - IMPORTANCE OF A CONFORMATIONALLY-RESTRICTED TEMPLATE IN THE DESIGN OF ENZYME-INHIBITORS/, Journal of the American Chemical Society, 117(45), 1995, pp. 11070-11074
STRUCTURE-ACTIVITY AND STRUCTURE-SIDE-EFFECT RELATIONSHIPS FOR THE QUINOLONE ANTIBACTERIALS (VOL 33, PG 685, 1994)
Authors: DOMAGALA JM
Citation: Jm. Domagala, STRUCTURE-ACTIVITY AND STRUCTURE-SIDE-EFFECT RELATIONSHIPS FOR THE QUINOLONE ANTIBACTERIALS (VOL 33, PG 685, 1994), Journal of antimicrobial chemotherapy, 34(5), 1994, pp. 851-851
STRUCTURE-ACTIVITY AND STRUCTURE-SIDE-EFFECT RELATIONSHIPS FOR THE QUINOLONE ANTIBACTERIALS
Authors: DOMAGALA JM
Citation: Jm. Domagala, STRUCTURE-ACTIVITY AND STRUCTURE-SIDE-EFFECT RELATIONSHIPS FOR THE QUINOLONE ANTIBACTERIALS, Journal of antimicrobial chemotherapy, 33(4), 1994, pp. 685-706
SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF NEW QUINOLONES CONTAINING A 7-[3-(1-AMINO-1-METHYLETHYL)-1-PYRROLIDINYL] MOIETY - GRAM-POSITIVE AGENTS WITH EXCELLENT ORAL ACTIVITY AND LOW SIDE-EFFECT POTENTIAL
Authors: HAGEN SE DOMAGALA JM GRACHECK SJ SESNIE JA STIER MA SUTO MJ
Citation: Se. Hagen et al., SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF NEW QUINOLONES CONTAINING A 7-[3-(1-AMINO-1-METHYLETHYL)-1-PYRROLIDINYL] MOIETY - GRAM-POSITIVE AGENTS WITH EXCELLENT ORAL ACTIVITY AND LOW SIDE-EFFECT POTENTIAL, Journal of medicinal chemistry, 37(6), 1994, pp. 733-738
A NOVEL NONPEPTIDE HIV-1 PROTEASE INHIBITOR - ELUCIDATION OF THE BINDING MODE AND ITS APPLICATION IN THE DESIGN OF RELATED ANALOGS
Authors: LUNNEY EA HAGEN SE DOMAGALA JM HUMBLET C KOSINSKI J TAIT BD WARMUS JS WILSON M FERGUSON D HUPE D TUMMINO PJ BALDWIN ET BHAT TN LIU BS ERICKSON JW
Citation: Ea. Lunney et al., A NOVEL NONPEPTIDE HIV-1 PROTEASE INHIBITOR - ELUCIDATION OF THE BINDING MODE AND ITS APPLICATION IN THE DESIGN OF RELATED ANALOGS, Journal of medicinal chemistry, 37(17), 1994, pp. 2664-2677
NOVEL SERIES OF ACHIRAL, LOW-MOLECULAR-WEIGHT, AND POTENT HIV-1 PROTEASE INHIBITORS
Authors: PRASAD JVNV PARA KS LUNNEY EA ORTWINE DF DUNBAR JB FERGUSON D TUMMINO PJ HUPE D TAIT BD DOMAGALA JM HUMBLET C BHAT TN LIU BS GUERIN DMA BALDWIN ET ERICKSON JW SAWYER TK
Citation: Jvnv. Prasad et al., NOVEL SERIES OF ACHIRAL, LOW-MOLECULAR-WEIGHT, AND POTENT HIV-1 PROTEASE INHIBITORS, Journal of the American Chemical Society, 116(15), 1994, pp. 6989-6990
IN-VITRO ANTIBACTERIAL ACTIVITIES OF PD 138312 AND PD 140248, NEW FLUORONAPHTHYRIDINES WITH OUTSTANDING GRAM-POSITIVE POTENCY
Authors: HUBAND MD COHEN MA MESERVEY MA ROLAND GE YODER SL DAZER ME DOMAGALA JM
Citation: Md. Huband et al., IN-VITRO ANTIBACTERIAL ACTIVITIES OF PD 138312 AND PD 140248, NEW FLUORONAPHTHYRIDINES WITH OUTSTANDING GRAM-POSITIVE POTENCY, Antimicrobial agents and chemotherapy, 37(12), 1993, pp. 2563-2570
SYNTHESIS AND ANTIMICROBIAL EVALUATION OF A SERIES OF 7-[3-AMINO (OR AMINOMETHYL)-4-ARYL (OR CYCLOPROPYL)-1-PYRROLIDINYL]-4-QUINOLONE- AND -1,8-NAPHTHYRIDONE-3-CARBOXYLIC ACIDS
Authors: BUCSH RA DOMAGALA JM LABORDE E SESNIE JC
Citation: Ra. Bucsh et al., SYNTHESIS AND ANTIMICROBIAL EVALUATION OF A SERIES OF 7-[3-AMINO (OR AMINOMETHYL)-4-ARYL (OR CYCLOPROPYL)-1-PYRROLIDINYL]-4-QUINOLONE- AND -1,8-NAPHTHYRIDONE-3-CARBOXYLIC ACIDS, Journal of medicinal chemistry, 36(26), 1993, pp. 4139-4151
Risultati: 1-18 |