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Results: 1-8 |
Results: 8
Intracellular inhibition of human neutrophil elastase by orally active pyrrolidine-trans-lactams (vol 11, pg 243, 2001)
Authors: Macdonald, SJF Dowle, MD Harrison, LA Spooner, JE Shah, P Johnson, MR Inglis, GGA Clarke, GDE Belton, DJ Smith, RA Molloy, CR Dixon, M Murkitt, G Godward, RE Skarzynski, T Singh, OMP Kumar, KA Hodgson, ST McDonald, E Hardy, GW Finch, H Humphreys, DC Fleetwood, G
Citation: Sjf. Macdonald et al., Intracellular inhibition of human neutrophil elastase by orally active pyrrolidine-trans-lactams (vol 11, pg 243, 2001), BIOORG MED, 11(9), 2001, pp. 1249-1249
The discovery of a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil Elastase - GW311616A a development candidate
Authors: Mcdonold, SJF Dowle, MD Harrison, LA Shah, P Johnson, MR Inglis, GGA Clarke, GDE Smith, RA Humphreys, D Molloy, CR Amour, A Dixon, M Murkitt, G Godward, RE Padfield, T Skarzynski, T Singh, OMP Kumar, KA Fleetwood, G Hodgson, ST Hardy, GW Fincha, H
Citation: Sjf. Mcdonold et al., The discovery of a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil Elastase - GW311616A a development candidate, BIOORG MED, 11(7), 2001, pp. 895-898
Intracellular inhibition of human neutrophil elastase by orally active pyrrolidine-trans-lactams
Authors: Macdonald, SJF Dowle, MD Harrison, LA Spooner, JE Shah, P Johnson, MR Inglis, GGA Clarke, GDE Belton, DJ Smith, RA Molloy, CR Dixon, M Murkitt, G Godward, RE Skarzynski, T Singh, OMP Kumar, KA Hodgson, ST McDonald, E Hardy, GW Finch, H
Citation: Sjf. Macdonald et al., Intracellular inhibition of human neutrophil elastase by orally active pyrrolidine-trans-lactams, BIOORG MED, 11(2), 2001, pp. 243-246
1,2,4-Dithiazolidine-3,5-dione: A nucleophilic isocyanate "building block"
Authors: Cane-Honeysett, DJ Dowle, MD Wood, ME
Citation: Dj. Cane-honeysett et al., 1,2,4-Dithiazolidine-3,5-dione: A nucleophilic isocyanate "building block", SYNLETT, (11), 2000, pp. 1622-1624
A stereoselective synthesis via a 5-exo-trig cyclisation of trans-2-oxohexahydro-2H-furo[3,2-b]pyrroles (pyrrolidine-trans-lactones) - potent, novel elastase inhibitors (vol 1, pg 3931, 1998)
Authors: Macdonald, SJF Mills, K Spooner, JE Upton, RJ Dowle, MD McDonald, E
Citation: Sjf. Macdonald et al., A stereoselective synthesis via a 5-exo-trig cyclisation of trans-2-oxohexahydro-2H-furo[3,2-b]pyrroles (pyrrolidine-trans-lactones) - potent, novel elastase inhibitors (vol 1, pg 3931, 1998), J CHEM S P1, (7), 1999, pp. 833-833
A flexible, practical, and stereoselective synthesis of enantiomerically pure trans-5-oxohexahydropyrrolo[3,2-b]pyrroles (pyrrolidine-trans-lactams),a new class of serine protease inhibitors, using acyliminium methodology
Authors: MacDonald, SJF Clarke, GDE Dowle, MD Harrison, LA Hodgson, ST Inglis, GGA Johnson, MR Shah, P Upton, RJ Walls, SB
Citation: Sjf. Macdonald et al., A flexible, practical, and stereoselective synthesis of enantiomerically pure trans-5-oxohexahydropyrrolo[3,2-b]pyrroles (pyrrolidine-trans-lactams),a new class of serine protease inhibitors, using acyliminium methodology, J ORG CHEM, 64(14), 1999, pp. 5166-5175
Synthesis of (+/-)-oxohexahydrofuro[3,2-b]pyrroles (pyrrolidine-trans-lactones) using acyl-iminium chemistry
Authors: Macdonald, SJF Spooner, JE Dowle, MD
Citation: Sjf. Macdonald et al., Synthesis of (+/-)-oxohexahydrofuro[3,2-b]pyrroles (pyrrolidine-trans-lactones) using acyl-iminium chemistry, SYNLETT, (12), 1998, pp. 1375-1377
A stereoselective synthesis via a 5-exo-trig cyclisation of trans-2-oxohexahydro-2H-furo[3,2-b]pyrroles (pyrrolidine-trans-lactones) - potent, novel elastase inhibitors
Authors: Macdonald, SJF Mills, K Spooner, JE Upton, RJ Dowle, MD
Citation: Sjf. Macdonald et al., A stereoselective synthesis via a 5-exo-trig cyclisation of trans-2-oxohexahydro-2H-furo[3,2-b]pyrroles (pyrrolidine-trans-lactones) - potent, novel elastase inhibitors, J CHEM S P1, (23), 1998, pp. 3931-3936
Risultati: 1-8 |