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Results: 1-9 |
Results: 9
Discovery and initial structure-activity relationships of trisubstituted ureas as thrombin receptor (PAR-1) antagonists
Authors: Barrow, JC Nantermet, PG Selnick, HG Glass, KL Ngo, PL Young, MB Pellicore, JM Breslin, MJ Hutchinson, JH Freidinger, RM Condra, C Karczewski, J Bednar, RA Gaul, SL Stern, A Gould, R Connolly, TM
Citation: Jc. Barrow et al., Discovery and initial structure-activity relationships of trisubstituted ureas as thrombin receptor (PAR-1) antagonists, BIOORG MED, 11(20), 2001, pp. 2691-2696
Cyclic imides as potent and selective alpha-1A adrenergic receptor antagonists
Authors: DiPardo, RM Patane, MA Newton, RC Price, RA Broten, TP Chang, RSL Ransom, RW Di Salvo, J Freidinger, RM Bock, MG
Citation: Rm. Dipardo et al., Cyclic imides as potent and selective alpha-1A adrenergic receptor antagonists, BIOORG MED, 11(14), 2001, pp. 1959-1962
The synthesis of a prodrug of doxorubicin designed to provide reduced systemic toxicity and greater target efficacy
Authors: Garsky, VM Lumma, PK Feng, DM Wai, J Ramjit, HG Sardana, MK Oliff, A Jones, RE DeFeo-Jones, D Freidinger, RM
Citation: Vm. Garsky et al., The synthesis of a prodrug of doxorubicin designed to provide reduced systemic toxicity and greater target efficacy, J MED CHEM, 44(24), 2001, pp. 4216-4224
Preparation and evaluation of 1,3-diaminocyclopentane-linked dihydropyrimidinone derivatives as selective alpha(1a)-receptor antagonists
Authors: Barrow, JC Glass, KL Selnick, HG Freidinger, RM Chang, RSL O'Malley, SS Woyden, C
Citation: Jc. Barrow et al., Preparation and evaluation of 1,3-diaminocyclopentane-linked dihydropyrimidinone derivatives as selective alpha(1a)-receptor antagonists, BIOORG MED, 10(17), 2000, pp. 1917-1920
Selective alpha(1a) adrenergic receptor antagonists based on 4-aryl-3,4-dihydropyridine-2-ones
Authors: Nantermet, PG Barrow, JC Selnick, HG Homnick, CF Freidinger, RM Chang, RSL O'Malley, SS Reiss, DR Broten, TP Ransom, RW Pettibone, DJ Olah, T Forray, C
Citation: Pg. Nantermet et al., Selective alpha(1a) adrenergic receptor antagonists based on 4-aryl-3,4-dihydropyridine-2-ones, BIOORG MED, 10(15), 2000, pp. 1625-1628
In vitro and in vivo evaluation of dihydropyrimidinone C-5 amides as potent and selective alpha(1A) receptor antagonists for the treatment of benign prostatic hyperplasia
Authors: Barrow, JC Nantermet, PG Selnick, HG Glass, KL Rittle, KE Gilbert, KF Steele, TG Homnick, CF Freidinger, RM Ransom, RW Kling, P Reiss, D Broten, TP Schorn, TW Chang, RSL O'Malley, SS Olah, TV Ellis, JD Barrish, A Kassahun, K Leppert, P Nagarathnam, D Forray, C
Citation: Jc. Barrow et al., In vitro and in vivo evaluation of dihydropyrimidinone C-5 amides as potent and selective alpha(1A) receptor antagonists for the treatment of benign prostatic hyperplasia, J MED CHEM, 43(14), 2000, pp. 2703-2718
Nonpeptidic ligands for peptide and protein receptors
Authors: Freidinger, RM
Citation: Rm. Freidinger, Nonpeptidic ligands for peptide and protein receptors, CURR OP C B, 3(4), 1999, pp. 395-406
Nonpeptide oxytocin antagonists: Analogs of L-371,257 with improved potency
Authors: Williams, PD Bock, MG Evans, BE Freidinger, RM Gallicchio, SN Guidotti, MT Jacobson, MA Kuo, MS Levy, MR Lis, EV Michelson, SR Pawluczyk, JM Perlow, DS Pettibone, DJ Quigley, AG Reiss, DR Salvatore, C Stauffer, KJ Woyden, CJ
Citation: Pd. Williams et al., Nonpeptide oxytocin antagonists: Analogs of L-371,257 with improved potency, BIOORG MED, 9(9), 1999, pp. 1311-1316
Design and synthesis of novel alpha(1a) adrenoceptor-selective antagonists. 2. Approaches to eliminate opioid agonist metabolites via modification oflinker and 4-methoxycarbonyl-4-phenylpiperidine moiety
Authors: Dhar, TGM Nagarathnam, D Marzabadi, MR Lagu, B Wong, WC Chiu, G Tyagarajan, S Miao, SW Zhang, FQ Sun, WY Tian, D Shen, QR Zhang, J Wetzel, JM Forray, C Chang, RSL Broten, TP Schorn, TW Chen, TB O'Malley, S Ransom, R Schneck, K Bendesky, R Harrell, CM Vyas, KP Zhang, KY Gilbert, J Pettibone, DJ Patane, MA Bock, MG Freidinger, RM Gluchowski, C
Citation: Tgm. Dhar et al., Design and synthesis of novel alpha(1a) adrenoceptor-selective antagonists. 2. Approaches to eliminate opioid agonist metabolites via modification oflinker and 4-methoxycarbonyl-4-phenylpiperidine moiety, J MED CHEM, 42(23), 1999, pp. 4778-4793
Risultati: 1-9 |