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Results: 1-25 | 26-35
Results: 1-25/35
MECHANISMS RESEARCH HIGHLIGHTS AT THE CHEMISTRY BIOLOGY INTERFACE - EDITORIAL OVERVIEW/
Authors: GERLT JA MARLETTA MA
Citation: Ja. Gerlt et Ma. Marletta, MECHANISMS RESEARCH HIGHLIGHTS AT THE CHEMISTRY BIOLOGY INTERFACE - EDITORIAL OVERVIEW/, Current opinion in chemical biology, 2(5), 1998, pp. 605-606
MECHANISTICALLY DIVERSE ENZYME SUPERFAMILIES - THE IMPORTANCE OF CHEMISTRY IN THE EVOLUTION OF CATALYSIS
Authors: GERLT JA BABBITT PC
Citation: Ja. Gerlt et Pc. Babbitt, MECHANISTICALLY DIVERSE ENZYME SUPERFAMILIES - THE IMPORTANCE OF CHEMISTRY IN THE EVOLUTION OF CATALYSIS, Current opinion in chemical biology, 2(5), 1998, pp. 607-612
EVOLUTION OF AN ENZYME ACTIVE-SITE - THE STRUCTURE OF A NEW CRYSTAL FORM OF MUCONATE LACTONIZING ENZYME COMPARED WITH MANDELATE RACEMASE AND ENOLASE
Authors: HASSON MS SCHLICHTING I MOULAI J TAYLOR K BARRETT W KENYON GL BABBITT PC GERLT JA PETSKO GA RINGE D
Citation: Ms. Hasson et al., EVOLUTION OF AN ENZYME ACTIVE-SITE - THE STRUCTURE OF A NEW CRYSTAL FORM OF MUCONATE LACTONIZING ENZYME COMPARED WITH MANDELATE RACEMASE AND ENOLASE, Proceedings of the National Academy of Sciences of the United Statesof America, 95(18), 1998, pp. 10396-10401
THE LOW BARRIER HYDROGEN-BOND IN ENZYMATIC CATALYSIS
Authors: CLELAND WW FREY PA GERLT JA
Citation: Ww. Cleland et al., THE LOW BARRIER HYDROGEN-BOND IN ENZYMATIC CATALYSIS, The Journal of biological chemistry, 273(40), 1998, pp. 25529-25532
EVOLUTION OF ENZYMATIC-ACTIVITIES IN THE ENOLASE SUPERFAMILY - PARTITIONING OF REACTIVE INTERMEDIATES BY (D)-GLUCARATE DEHYDRATASE FROM PSEUDOMONAS-PUTIDA
Authors: PALMER DRJ HUBBARD BK GERLT JA
Citation: Drj. Palmer et al., EVOLUTION OF ENZYMATIC-ACTIVITIES IN THE ENOLASE SUPERFAMILY - PARTITIONING OF REACTIVE INTERMEDIATES BY (D)-GLUCARATE DEHYDRATASE FROM PSEUDOMONAS-PUTIDA, Biochemistry (Easton), 37(41), 1998, pp. 14350-14357
EVOLUTION OF ENZYMATIC-ACTIVITIES IN THE ENOLASE SUPERFAMILY - CRYSTAL-STRUCTURE OF (D)-GLUCARATE DEHYDRATASE FROM PSEUDOMONAS-PUTIDA
Authors: GULICK AM PALMER DRJ BABBITT PC GERLT JA RAYMENT I
Citation: Am. Gulick et al., EVOLUTION OF ENZYMATIC-ACTIVITIES IN THE ENOLASE SUPERFAMILY - CRYSTAL-STRUCTURE OF (D)-GLUCARATE DEHYDRATASE FROM PSEUDOMONAS-PUTIDA, Biochemistry (Easton), 37(41), 1998, pp. 14358-14368
EVOLUTION OF ENZYMATIC-ACTIVITIES IN THE ENOLASE SUPERFAMILY - CHARACTERIZATION OF THE (D)-GLUCARATE GALACTARATE CATABOLIC PATHWAY IN ESCHERICHIA-COLI/
Authors: HUBBARD BK KOCH M PALMER DRJ BABBITT PC GERLT JA
Citation: Bk. Hubbard et al., EVOLUTION OF ENZYMATIC-ACTIVITIES IN THE ENOLASE SUPERFAMILY - CHARACTERIZATION OF THE (D)-GLUCARATE GALACTARATE CATABOLIC PATHWAY IN ESCHERICHIA-COLI/, Biochemistry (Easton), 37(41), 1998, pp. 14369-14375
THE CRYSTAL-STRUCTURE OF BENZOYLFORMATE DECARBOXYLASE AT 1.6 ANGSTROMRESOLUTION - DIVERSITY OF CATALYTIC RESIDUES IN THIAMIN DIPHOSPHATE-DEPENDENT ENZYMES
Authors: HASSON MS MUSCATE A MCLEISH MJ POLOVNIKOVA LS GERLT JA KENYON GL PETSKO GA RINGE D
Citation: Ms. Hasson et al., THE CRYSTAL-STRUCTURE OF BENZOYLFORMATE DECARBOXYLASE AT 1.6 ANGSTROMRESOLUTION - DIVERSITY OF CATALYTIC RESIDUES IN THIAMIN DIPHOSPHATE-DEPENDENT ENZYMES, Biochemistry, 37(28), 1998, pp. 9918-9930
UNDERSTANDING ENZYMATIC CATALYSIS - THE IMPORTANCE OF SHORT, STRONG HYDROGEN-BONDS
Authors: GERLT JA KREEVOY MM CLELAND WW FREY PA
Citation: Ja. Gerlt et al., UNDERSTANDING ENZYMATIC CATALYSIS - THE IMPORTANCE OF SHORT, STRONG HYDROGEN-BONDS, Chemistry & biology, 4(4), 1997, pp. 259-267
THE ENOLASE SUPERFAMILY - DIFFERENT REACTIONS CATALYZED BY SIMILAR ACTIVE-SITES
Authors: GERLT JA BABBITT PC
Citation: Ja. Gerlt et Pc. Babbitt, THE ENOLASE SUPERFAMILY - DIFFERENT REACTIONS CATALYZED BY SIMILAR ACTIVE-SITES, The FASEB journal, 11(9), 1997, pp. 876-876
STEREOCHEMISTRY OF THE REACTION CATALYZED BY GALACTONATE DEHYDRATASE
Authors: WIECZOREK SJ MRACHKO GT GERLT JA
Citation: Sj. Wieczorek et al., STEREOCHEMISTRY OF THE REACTION CATALYZED BY GALACTONATE DEHYDRATASE, The FASEB journal, 11(9), 1997, pp. 934-934
UNDERSTANDING ENZYME SUPERFAMILIES - CHEMISTRY AS THE FUNDAMENTAL DETERMINANT IN THE EVOLUTION OF NEW CATALYTIC ACTIVITIES
Authors: BABBITT PC GERLT JA
Citation: Pc. Babbitt et Ja. Gerlt, UNDERSTANDING ENZYME SUPERFAMILIES - CHEMISTRY AS THE FUNDAMENTAL DETERMINANT IN THE EVOLUTION OF NEW CATALYTIC ACTIVITIES, The Journal of biological chemistry, 272(49), 1997, pp. 30591-30594
IMPORTANCE OF MECHANISTIC IMPERATIVES IN ENZYME-CATALYZED BETA-ELIMINATION REACTIONS - STEREOCHEMICAL CONSEQUENCES OF THE DEHYDRATION REACTIONS CATALYZED BY D-GALACTONATE DEHYDRATASE FROM ESCHERICHIA-COLI AND D-GLUCARATE DEHYDRATASE FROM PSEUDOMONAS-PUTIDA
Authors: PALMER DRJ WIECZOREK SJ HUBBARD BK MRACHKO GT GERLT JA
Citation: Drj. Palmer et al., IMPORTANCE OF MECHANISTIC IMPERATIVES IN ENZYME-CATALYZED BETA-ELIMINATION REACTIONS - STEREOCHEMICAL CONSEQUENCES OF THE DEHYDRATION REACTIONS CATALYZED BY D-GALACTONATE DEHYDRATASE FROM ESCHERICHIA-COLI AND D-GLUCARATE DEHYDRATASE FROM PSEUDOMONAS-PUTIDA, Journal of the American Chemical Society, 119(40), 1997, pp. 9580-9581
METAL REQUIREMENTS OF MANDELATE RACEMASE, MUCONATE LACTONIZING ENZYMEAND GLUCARATE DEHYDRATASE
Authors: BUDIHAS SR BARRETT WC GERLT JA POYNER RR REED GH
Citation: Sr. Budihas et al., METAL REQUIREMENTS OF MANDELATE RACEMASE, MUCONATE LACTONIZING ENZYMEAND GLUCARATE DEHYDRATASE, The FASEB journal, 10(6), 1996, pp. 1420-1420
ENZYME-CATALYZED ENOLIZATION REACTIONS - A THEORETICAL-STUDY ON THE ENERGETICS OF CONCERTED AND STEPWISE PATHWAYS
Authors: SARGENT AL ROLLOG ME ALMLOF JE GASSMAN PG GERLT JA
Citation: Al. Sargent et al., ENZYME-CATALYZED ENOLIZATION REACTIONS - A THEORETICAL-STUDY ON THE ENERGETICS OF CONCERTED AND STEPWISE PATHWAYS, Journal of molecular structure. Theochem, 388, 1996, pp. 145-159
THE ENOLASE SUPERFAMILY - A GENERAL STRATEGY FOR ENZYME-CATALYZED ABSTRACTION OF THE ALPHA-PROTONS OF CARBOXYLIC-ACIDS
Authors: BABBITT PC HASSON MS WEDEKIND JE PALMER DRJ BARRETT WC REED GH RAYMENT I RINGE D KENYON GL GERLT JA
Citation: Pc. Babbitt et al., THE ENOLASE SUPERFAMILY - A GENERAL STRATEGY FOR ENZYME-CATALYZED ABSTRACTION OF THE ALPHA-PROTONS OF CARBOXYLIC-ACIDS, Biochemistry, 35(51), 1996, pp. 16489-16501
GLUCARATE DEHYDRATASE - A STEREORANDOM ENZYME FROM THE ENOLASE SUPERFAMILY
Authors: PALMER DRJ GERLT JA
Citation: Drj. Palmer et Ja. Gerlt, GLUCARATE DEHYDRATASE - A STEREORANDOM ENZYME FROM THE ENOLASE SUPERFAMILY, Biochemistry, 35(28), 1996, pp. 38-38
3'-STRAND AND 5'-STRAND CLEAVAGE REACTIONS CATALYZED BY THE FPG PROTEIN FROM ESCHERICHIA-COLI OCCUR VIA SUCCESSIVE BETA-ELIMINATION AND DELTA-ELIMINATION MECHANISMS, RESPECTIVELY
Authors: BHAGWAT M GERLT JA
Citation: M. Bhagwat et Ja. Gerlt, 3'-STRAND AND 5'-STRAND CLEAVAGE REACTIONS CATALYZED BY THE FPG PROTEIN FROM ESCHERICHIA-COLI OCCUR VIA SUCCESSIVE BETA-ELIMINATION AND DELTA-ELIMINATION MECHANISMS, RESPECTIVELY, Biochemistry, 35(2), 1996, pp. 659-665
MECHANISM OF THE REACTION CATALYZED BY MANDELATE RACEMASE - STRUCTUREAND MECHANISTIC PROPERTIES OF THE D270N MUTANT
Authors: SCHAFER SL BARRETT WC KALLARAKAL AT MITRA B KOZARICH JW GERLT JA CLIFTON JG PETSKO GA KENYON GL
Citation: Sl. Schafer et al., MECHANISM OF THE REACTION CATALYZED BY MANDELATE RACEMASE - STRUCTUREAND MECHANISTIC PROPERTIES OF THE D270N MUTANT, Biochemistry, 35(18), 1996, pp. 5662-5669
MECHANISM OF THE REACTION CATALYZED BY ACETOACETATE DECARBOXYLASE - IMPORTANCE OF LYSINE-116 IN DETERMINING THE PK(A) OF ACTIVE-SITE LYSINE-115
Authors: HIGHBARGER LA GERLT JA KENYON GL
Citation: La. Highbarger et al., MECHANISM OF THE REACTION CATALYZED BY ACETOACETATE DECARBOXYLASE - IMPORTANCE OF LYSINE-116 IN DETERMINING THE PK(A) OF ACTIVE-SITE LYSINE-115, Biochemistry, 35(1), 1996, pp. 41-46
THE MANDELATE RACEMASE MUCONATE LACTONIZING ENZYME/GALACTONATE DEHYDRATASE ENZYME SUPERFAMILY/
Authors: GERLT JA
Citation: Ja. Gerlt, THE MANDELATE RACEMASE MUCONATE LACTONIZING ENZYME/GALACTONATE DEHYDRATASE ENZYME SUPERFAMILY/, The FASEB journal, 9(6), 1995, pp. 1257-1257
ANOTHER UNEXPECTED ENZYME SUPERFAMILY - DEHYDRATASES, DECARBOXYLASES,AND ALDOLASES
Authors: BABBITT PC GERLT JA
Citation: Pc. Babbitt et Ja. Gerlt, ANOTHER UNEXPECTED ENZYME SUPERFAMILY - DEHYDRATASES, DECARBOXYLASES,AND ALDOLASES, The FASEB journal, 9(6), 1995, pp. 1266-1266
MECHANISM OF THE REACTION CATALYZED BY MANDELATE RACEMASE - STUDIES OF THE ELECTROPHILIC CATALYST AND ENOLIC INTERMEDIATE
Authors: BARRETT WC BUDIHAS SR GERLT JA
Citation: Wc. Barrett et al., MECHANISM OF THE REACTION CATALYZED BY MANDELATE RACEMASE - STUDIES OF THE ELECTROPHILIC CATALYST AND ENOLIC INTERMEDIATE, The FASEB journal, 9(6), 1995, pp. 1296-1296
MECHANISM OF THE REACTION CATALYZED BY MANDELATE RACEMASE - IMPORTANCE OF ELECTROPHILIC CATALYSIS BY GLUTAMIC-ACID-317
Authors: MITRA B KALLARAKAL AT KOZARICH JW GERLT JA CLIFTON JG PETSKO GA KENYON GL
Citation: B. Mitra et al., MECHANISM OF THE REACTION CATALYZED BY MANDELATE RACEMASE - IMPORTANCE OF ELECTROPHILIC CATALYSIS BY GLUTAMIC-ACID-317, Biochemistry, 34(9), 1995, pp. 2777-2787
MECHANISM OF THE REACTION CATALYZED BY MANDELATE RACEMASE - STRUCTUREAND MECHANISTIC PROPERTIES OF THE K166R MUTANT
Authors: KALLARAKAL AT MITRA B KOZARICH JW GERLT JA CLIFTON JG PETSKO GA KENYON GL
Citation: At. Kallarakal et al., MECHANISM OF THE REACTION CATALYZED BY MANDELATE RACEMASE - STRUCTUREAND MECHANISTIC PROPERTIES OF THE K166R MUTANT, Biochemistry, 34(9), 1995, pp. 2788-2797
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