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Results: 1-19 |
Results: 19
DESIGN, SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONSHIP STUDIES OF NOVEL 4,4-BIS(TRIFLUOROMETHYL)IMIDAZOLINES AS ACYL-COA - CHOLESTEROL ACYLTRANSFERASE (ACAT) INHIBITORS AND ANTIHYPERCHOLESTEROLEMIC AGENTS
Authors: LI HY DELUCCA I BOSWELL GA BILLHEIMER JT DRUMMOND S GILLIES PJ ROBINSON C
Citation: Hy. Li et al., DESIGN, SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONSHIP STUDIES OF NOVEL 4,4-BIS(TRIFLUOROMETHYL)IMIDAZOLINES AS ACYL-COA - CHOLESTEROL ACYLTRANSFERASE (ACAT) INHIBITORS AND ANTIHYPERCHOLESTEROLEMIC AGENTS, Bioorganic & medicinal chemistry, 5(7), 1997, pp. 1345-1361
DMP-504, A NOVEL HYDROGEL BILE-ACID SEQUESTRANT - I - EQUILIBRIUM BINDING-PROPERTIES AND COMPUTER-SIMULATION OF HUMAN BILE-FLOW
Authors: SHIMSHICK EJ FIGULY GD GRIMMINGER LC HAINER JW JENSEN JH LEIPOLD RJ ROYCE SD GILLIES PJ
Citation: Ej. Shimshick et al., DMP-504, A NOVEL HYDROGEL BILE-ACID SEQUESTRANT - I - EQUILIBRIUM BINDING-PROPERTIES AND COMPUTER-SIMULATION OF HUMAN BILE-FLOW, Drug development research, 41(2), 1997, pp. 58-64
DMP-504, A NOVEL HYDROGEL BILE-ACID SEQUESTRANT - II - LIPID-LOWERINGPHARMACOLOGY IN THE HAMSTER
Authors: GILLIES PJ BILLHEIMER JT BLACKSTON VA CROMLEY DA FIGULY GD FISCHER RT GERMAIN SJ GODONIS HE GORKO MA GRIMMINGER LC HARVEY SJ JENSEN JH KIERAS CJ ROYCE SD PAUTLER HC SHIMSHICK EJ STEVENSON RC HAINER JW
Citation: Pj. Gillies et al., DMP-504, A NOVEL HYDROGEL BILE-ACID SEQUESTRANT - II - LIPID-LOWERINGPHARMACOLOGY IN THE HAMSTER, Drug development research, 41(2), 1997, pp. 65-75
DMP-504, A NOVEL HYDROGEL BILE-ACID SEQUESTRANT - III - SAFETY, TOLERABILITY, AND CHOLESTEROL-LOWERING IN HEALTHY HYPERCHOLESTEROLEMIC SUBJECTS
Authors: HAINER JW HUNNINGHAKE DB BENEDEK IH BROYLES FE GARNER DM JENKINS RM MCGINN A PIENIASZEK HJ LONDON E GILLIES PJ
Citation: Jw. Hainer et al., DMP-504, A NOVEL HYDROGEL BILE-ACID SEQUESTRANT - III - SAFETY, TOLERABILITY, AND CHOLESTEROL-LOWERING IN HEALTHY HYPERCHOLESTEROLEMIC SUBJECTS, Drug development research, 41(2), 1997, pp. 76-84
PREPARATION AND CHARACTERIZATION OF NOVEL POLY(ALKYLAMINE)-BASED HYDROGELS DESIGNED FOR USE AS BILE-ACID SEQUESTRANTS
Authors: FIGULY GD ROYCE SD KHASAT NP SCHOCK LE WU SLD DAVIDSON F CAMPBELL GC KEATING MY CHEN HW SHIMSHICK EJ FISCHER RT GRIMMINGER LC THOMAS BE SMITH LH GILLIES PJ
Citation: Gd. Figuly et al., PREPARATION AND CHARACTERIZATION OF NOVEL POLY(ALKYLAMINE)-BASED HYDROGELS DESIGNED FOR USE AS BILE-ACID SEQUESTRANTS, Macromolecules, 30(20), 1997, pp. 6174-6184
GENE-EXPRESSION OF ACYL-COENZYME-A - CHOLESTEROL ACYLTRANSFERASE IS UP-REGULATED IN HUMAN MONOCYTES DURING DIFFERENTIATION AND FOAM CELL-FORMATION
Authors: WANG HX GERMAIN SJ BENFIELD PP GILLIES PJ
Citation: Hx. Wang et al., GENE-EXPRESSION OF ACYL-COENZYME-A - CHOLESTEROL ACYLTRANSFERASE IS UP-REGULATED IN HUMAN MONOCYTES DURING DIFFERENTIATION AND FOAM CELL-FORMATION, Arteriosclerosis, thrombosis, and vascular biology, 16(6), 1996, pp. 809-814
NOVEL 4,4-BIS(TRIFLUOROMETHYL) IMIDAZOLINES AS STEREOSPECIFIC AND ORALLY-ACTIVE ACYL COA - CHOLESTEROL ACYLTRANSFERASE (ACAT) INHIBITORS AND ANTIHYPERCHOLESTEROLEMIC AGENTS
Authors: BOSWELL GA LI HY DELUCCA I BILLHEIMER JT DRUMMOND S GILLIES PJ ROBINSON C
Citation: Ga. Boswell et al., NOVEL 4,4-BIS(TRIFLUOROMETHYL) IMIDAZOLINES AS STEREOSPECIFIC AND ORALLY-ACTIVE ACYL COA - CHOLESTEROL ACYLTRANSFERASE (ACAT) INHIBITORS AND ANTIHYPERCHOLESTEROLEMIC AGENTS, Bioorganic & medicinal chemistry letters, 6(7), 1996, pp. 885-888
ACYL COA-CHOLESTEROL ACYLTRANSFERASE (ACAT) INHIBITORS - UREAS BEARING HETEROCYCLIC GROUPS BIOISOSTERIC FOR AN IMIDAZOLE
Authors: WILDE RG BILLHEIMER JT GERMAIN SJ GILLIES PJ HIGLEY CA KEZAR HS MADUSKUIE TP SHIMSHICK ES WEXLER RR
Citation: Rg. Wilde et al., ACYL COA-CHOLESTEROL ACYLTRANSFERASE (ACAT) INHIBITORS - UREAS BEARING HETEROCYCLIC GROUPS BIOISOSTERIC FOR AN IMIDAZOLE, Bioorganic & medicinal chemistry letters, 5(2), 1995, pp. 167-172
ACYL-COA-CHOLESTEROL ACYLTRANSFERASE (ACAT) INHIBITORS - HETEROCYCLICBIOISOSTERES FOR THE UREA GROUP IN DUP-128
Authors: WILDE RG KLACZKIEWICZ JD BILLHEIMER JT WEXLER RR GILLIES PJ
Citation: Rg. Wilde et al., ACYL-COA-CHOLESTEROL ACYLTRANSFERASE (ACAT) INHIBITORS - HETEROCYCLICBIOISOSTERES FOR THE UREA GROUP IN DUP-128, Bioorganic & medicinal chemistry letters, 5(2), 1995, pp. 177-180
HEPATIC AND ADRENAL CHANGES IN RABBITS ASSOCIATED WITH HYPERLIPIDEMIACAUSED BY A SEMISYNTHETIC DIET
Authors: HAUSNER EA SCHLINGMANN KL CHEN HW GILLIES PJ KIERAS CJ ROSS PE VANPELT CS
Citation: Ea. Hausner et al., HEPATIC AND ADRENAL CHANGES IN RABBITS ASSOCIATED WITH HYPERLIPIDEMIACAUSED BY A SEMISYNTHETIC DIET, Laboratory animal science, 45(6), 1995, pp. 663-670
DESIGN, SYNTHESIS, AND STRUCTURE-ACTIVITY RELATIONSHIP STUDIES FOR A NEW IMIDAZOLE SERIES OF J774 MACROPHAGE SPECIFIC ACYL-COA-CHOLESTEROL ACYLTRANSFERASE (ACAT) INHIBITORS
Authors: MADUSKUIE TP WILDE RG BILLHEIMER JT CROMLEY DA GERMAIN S GILLIES PJ HIGLEY CA JOHNSON AL PENNEV P SHIMSHICK EJ WEXLER RR
Citation: Tp. Maduskuie et al., DESIGN, SYNTHESIS, AND STRUCTURE-ACTIVITY RELATIONSHIP STUDIES FOR A NEW IMIDAZOLE SERIES OF J774 MACROPHAGE SPECIFIC ACYL-COA-CHOLESTEROL ACYLTRANSFERASE (ACAT) INHIBITORS, Journal of medicinal chemistry, 38(7), 1995, pp. 1067-1083
INHIBITION OF HEPATIC ACAT DECREASES APO-B SECRETION IN MINIATURE PIGS FED A CHOLESTEROL-FREE DIET
Authors: HUFF MW TELFORD DE BARRETT PHR BILLHEIMER JT GILLIES PJ
Citation: Mw. Huff et al., INHIBITION OF HEPATIC ACAT DECREASES APO-B SECRETION IN MINIATURE PIGS FED A CHOLESTEROL-FREE DIET, Arteriosclerosis and thrombosis, 14(9), 1994, pp. 1498-1508
ACYL COA-CHOLESTEROL ACYLTRANSFERASE (ACAT) INHIBITORS - SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONSHIP STUDIES OF A NEW SERIES OF TRISUBSTITUTED IMIDAZOLES
Authors: HIGLEY CA WILDE RG MADUSKUIE TP JOHNSON AL PENNEV P BILLHEIMER JT ROBINSON CS GILLIES PJ WEXLER RR
Citation: Ca. Higley et al., ACYL COA-CHOLESTEROL ACYLTRANSFERASE (ACAT) INHIBITORS - SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONSHIP STUDIES OF A NEW SERIES OF TRISUBSTITUTED IMIDAZOLES, Journal of medicinal chemistry, 37(21), 1994, pp. 3511-3522
EFFECT OF THE ACYL-COA-CHOLESTEROL ACYLTRANSFERASE INHIBITOR DUP-128 ON CHOLESTEROL ABSORPTION AND SERUM-CHOLESTEROL IN HUMANS
Authors: HAINER JW TERRY JG CONNELL JM ZYRUK H JENKINS RM SHAND DL GILLIES PJ LIVAK KJ HUNT TL CROUSE JR
Citation: Jw. Hainer et al., EFFECT OF THE ACYL-COA-CHOLESTEROL ACYLTRANSFERASE INHIBITOR DUP-128 ON CHOLESTEROL ABSORPTION AND SERUM-CHOLESTEROL IN HUMANS, Clinical pharmacology and therapeutics, 56(1), 1994, pp. 65-74
GENE-EXPRESSION OF ACYL-COENZYME-A CHOLESTEROL ACYLTRANSFERASE IS UP-REGULATED IN HUMAN MONOCYTES DURING DIFFERENTIATION AND FOAM CELL-FORMATION
Authors: WANG HX BENFIELD PA GERMAIN SJ GILLIES PJ
Citation: Hx. Wang et al., GENE-EXPRESSION OF ACYL-COENZYME-A CHOLESTEROL ACYLTRANSFERASE IS UP-REGULATED IN HUMAN MONOCYTES DURING DIFFERENTIATION AND FOAM CELL-FORMATION, Circulation, 90(4), 1994, pp. 351-351
GENE-EXPRESSION OF ACYL-COENZYME-A CHOLESTEROL ACYLTRANSFERASE IS UP-REGULATED IN HUMAN MONOCYTES DURING DIFFERENTIATION AND FOAM CELL-FORMATION
Authors: WANG HX BENFIELD PA GERMAIN SJ GILLIES PJ
Citation: Hx. Wang et al., GENE-EXPRESSION OF ACYL-COENZYME-A CHOLESTEROL ACYLTRANSFERASE IS UP-REGULATED IN HUMAN MONOCYTES DURING DIFFERENTIATION AND FOAM CELL-FORMATION, Circulation, 90(4), 1994, pp. 351-351
WHOLE-BLOOD AND PLASMA-CONCENTRATIONS OF 4-HYDROXY-2-NONENAL IN WATANABE HERITABLE HYPERLIPIDEMIC VERSUS NEW-ZEALAND WHITE-RABBITS
Authors: KINTER M ROBINSON CS GRIMMINGER LC GILLIES PJ SHIMSHICK EJ AYERS C
Citation: M. Kinter et al., WHOLE-BLOOD AND PLASMA-CONCENTRATIONS OF 4-HYDROXY-2-NONENAL IN WATANABE HERITABLE HYPERLIPIDEMIC VERSUS NEW-ZEALAND WHITE-RABBITS, Biochemical and biophysical research communications, 199(2), 1994, pp. 671-675
INCREASED PLATELET GPIIB IIIA RECEPTOR SENSITIVITY IN WATANABE HERITABLE HYPERLIPIDEMIC RABBITS/
Authors: PEASE LJ ROBINSON CS GILLIES PJ BOZARTH JM REILLY TM MOUSA SA
Citation: Lj. Pease et al., INCREASED PLATELET GPIIB IIIA RECEPTOR SENSITIVITY IN WATANABE HERITABLE HYPERLIPIDEMIC RABBITS/, Biochemical archives, 9(4), 1993, pp. 311-320
INHIBITION OF HEPATIC ACAT DECREASES APOLIPOPROTEIN-B SECRETION IN MINIATURE PIGS FED A CHOLESTEROL-FREE DIET
Authors: HUFF MW TELFORD DE BARRETT PH BILLHEIMER JT GILLIES PJ
Citation: Mw. Huff et al., INHIBITION OF HEPATIC ACAT DECREASES APOLIPOPROTEIN-B SECRETION IN MINIATURE PIGS FED A CHOLESTEROL-FREE DIET, Circulation, 88(4), 1993, pp. 76-76
Risultati: 1-19 |