Authors:
Steinmetz, MO
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van Oostrum, J
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Authors:
Furet, P
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Citation: P. Furet et al., Modeling of the binding mode of a non-covalent inhibitor of the 20S proteasome. Application to structure-based analogue design, BIOORG MED, 11(10), 2001, pp. 1321-1324
Authors:
Kammerer, RA
Jaravine, VA
Frank, S
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Lustig, A
Garcia-Echeverria, C
Alexandrescu, AT
Engel, J
Steinmetz, MO
Citation: Ra. Kammerer et al., An intrahelical salt bridge within the trigger site stabilizes the GCN4 leucine zipper, J BIOL CHEM, 276(17), 2001, pp. 13685-13688
Authors:
Fretz, H
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Citation: H. Fretz et al., Structure-based design of compounds inhibiting Grb2-SH2 mediated protein-protein interactions in signal transduction pathways, CUR PHARM D, 6(18), 2000, pp. 1777-1796
Authors:
Altmann, KH
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Garcia-Echeverria, C
Citation: Kh. Altmann et al., Synthesis and hybridization properties of polyamide based nucleic acid analogues incorporating pyrrolidine-derived nucleoamino acids, BIOORG MED, 10(9), 2000, pp. 929-933
Authors:
Furet, P
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Press, NJ
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Citation: P. Furet et al., Structure-based design and synthesis of phosphinate isosteres of phosphotyrosine for incorporation in Grb2-SH2 domain inhibitors. Part 1, BIOORG MED, 10(20), 2000, pp. 2337-2341
Authors:
Walker, CV
Caravatti, G
Denholm, AA
Egerton, J
Faessler, A
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Gay, B
Irving, E
Jones, K
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Press, NJ
Woods, J
Citation: Cv. Walker et al., Structure-based design and synthesis of phosphinate isosteres of phosphotyrosine for incorporation in Grb2-SH2 domain inhibitors. Part 2, BIOORG MED, 10(20), 2000, pp. 2343-2346
Authors:
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Citation: C. Garcia-echeverria et al., ATP site-directed competitive and irreversible inhibitors of protein kinases, MED RES REV, 20(1), 2000, pp. 28-57
Authors:
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Citation: P. Chene et al., A small synthetic peptide, which inhibits the p53-hdm2 interaction, stimulates the p53 pathway in tumour cell lines, J MOL BIOL, 299(1), 2000, pp. 245-253
Authors:
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Citation: C. Garcia-echeverria et al., Discovery of potent antagonists of the interaction between human double minute 2 and tumor suppressor p53, J MED CHEM, 43(17), 2000, pp. 3205-3208
Authors:
Garcia-Echeverria, C
Gay, B
Rahuel, J
Furet, P
Citation: C. Garcia-echeverria et al., Mapping the X+1 binding site of the Grb2-SH2 domain with alpha,alpha-disubstituted cyclic alpha-amino acids, BIOORG MED, 9(20), 1999, pp. 2915-2920
Authors:
Furet, P
Garcia-Echeverria, C
Gay, B
Schoepfer, J
Zeller, M
Rahuel, J
Citation: P. Furet et al., Structure-based design, synthesis, and X-ray crystallography of a high-affinity antagonist of the Grb2-SH2 domain containing an asparagine mimetic, J MED CHEM, 42(13), 1999, pp. 2358-2363
Authors:
Geiser, M
Schultz, D
Le Cardinal, A
Voshol, H
Garcia-Echeverria, C
Citation: M. Geiser et al., Identification of the human melanoma-associated chondroitin sulfate proteoglycan antigen epitope recognized by the antitumor monoclonal antibody 763.74 from a peptide phage library, CANCER RES, 59(4), 1999, pp. 905-910