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Takeuchi, K
Bastian, JA
Gifford-Moore, DS
Harper, RW
Miller, SC
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Sall, DJ
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Fisher, MJ
Citation: K. Takeuchi et al., 1,2-disubstituted indole, azaindole and benzimidazole derivatives possessing amine moiety: A novel series of thrombin inhibitors, BIOORG MED, 10(20), 2000, pp. 2347-2351
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Takeuchi, K
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Harper, RW
Lin, HS
Gifford-Moore, DS
Richett, ME
Sall, DJ
Smith, GF
Zhang, MS
Citation: K. Takeuchi et al., Diamino benzo[b]thiophene derivatives as a novel class of active site directed thrombin inhibitors. Part 6: Further focus on the contracted C4 '-sidechain analogues, BIOORG MED, 10(11), 2000, pp. 1199-1202
Authors:
Wiley, MR
Weir, LC
Briggs, S
Bryan, NA
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Campbell, C
Chirgadze, NY
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Kyle, JA
Masters, JJ
Ratz, AM
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Shuman, RT
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Tinsley, JM
Towner, RD
Wilson, A
Yee, YK
Citation: Mr. Wiley et al., Structure-based design of potent, amidine-derived inhibitors of factor Xa:Evaluation of selectivity, anticoagulant activity, and antithrombotic activity, J MED CHEM, 43(5), 2000, pp. 883-899
Authors:
Sall, DJ
Bailey, DL
Bastian, JA
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Chirgadze, NY
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Gifford-Moore, DS
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Klimkowski, VJ
Kohn, TJ
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Palkowitz, AD
Richett, ME
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Zhang, MS
Citation: Dj. Sall et al., Diamino benzo[b]thiophene derivatives as a novel class of active site directed thrombin inhibitors. 5. Potency, efficacy, and pharmacokinetic properties of modified C-3 side chain derivatives, J MED CHEM, 43(4), 2000, pp. 649-663
Authors:
Masters, JJ
Franciskovich, JB
Tinsley, JM
Campbell, C
Campbell, JB
Craft, TJ
Froelich, LL
Gifford-Moore, DS
Hay, LA
Herron, DK
Klimkowski, VJ
Kurz, KD
Metz, JT
Ratz, AM
Shuman, RT
Smith, GF
Smith, T
Towner, RD
Wiley, MR
Wilson, A
Yee, YK
Citation: Jj. Masters et al., Non-amidine-containing 1,2-dibenzamidobenzene inhibitors of human factor Xa with potent anticoagulant and antithrombotic activity, J MED CHEM, 43(11), 2000, pp. 2087-2092
Authors:
Takeuchi, K
Kohn, TJ
Sall, DJ
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McCowan, JR
Smith, GF
Gifford-Moore, DS
Citation: K. Takeuchi et al., Dibasic benzo[b]thiophene derivatives as a novel class of active site directed thrombin inhibitors: 4. SAR studies on the conformationally restrictedC3-side chain of hydroxybenzo[b]thiophenes, BIOORG MED, 9(5), 1999, pp. 759-764
Authors:
Zhang, MS
Bailey, DL
Bastian, JA
Briggs, SL
Chirgadze, NY
Clawson, DK
Denney, ML
Gifford-Moore, DS
Harper, RW
Johnson, LM
Klimkowski, VJ
Kohn, TJ
Lin, HS
McCowan, JR
Richett, ME
Sall, DJ
Smith, AJ
Smith, GF
Snyder, DW
Takeuchi, K
Utterback, BG
Yan, SCB
Citation: Ms. Zhang et al., Dibasic benzo[b]thiophene derivatives as a novel class of active site directed thrombin inhibitors: 2. Sidechain optimization and demonstration of invivo efficacy, BIOORG MED, 9(5), 1999, pp. 775-780
Authors:
Bastian, JA
Chirgadze, N
Denney, ML
Gifford-Moore, DS
Sall, DJ
Smith, GF
Wikel, JH
Citation: Ja. Bastian et al., Diamino benzo[b]thiophene derivatives as a novel class of active site directed thrombin inhibitors: 3. Enhancing activity by imposing conformational restriction in the C-4" side chain, BIOORG MED, 9(3), 1999, pp. 363-368
Authors:
Wiley, MR
Weir, LC
Briggs, SI
Chirgadze, NY
Clawson, D
Gifford-Moore, DS
Schacht, AL
Smith, GF
Vasudevan, V
Zornes, LL
Klimkowski, VJ
Citation: Mr. Wiley et al., The design of potent, selective, non-covalent, peptide thrombin inhibitorsutilizing imidazole as a S1 binding element, BIOORG MED, 9(18), 1999, pp. 2767-2772
Authors:
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Bronson, DD
Gillespie, JE
Gifford-Moore, DS
Kalter, K
Lynch, MP
McCowan, JR
Redick, CC
Sall, DJ
Smith, GF
Foglesong, RJ
Citation: Mg. Johnson et al., Solid phase chemistry approach to the SAR development of a novel class of active site-directed thrombin inhibitors, TETRAHEDRON, 55(39), 1999, pp. 11641-11652