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Results: 1-11 |
Results: 11
SYNTHESIS OF 5,6-DIHYDRO-4-HYDROXY-2-PYRONES AS HIV-1 PROTEASE INHIBITORS - THE PROFOUND EFFECT OF POLARITY ON ANTIVIRAL ACTIVITY
Authors: HAGEN SE PRASAD JVNV BOYER FE DOMAGALA JM ELLSWORTH EL GAJDA C HAMILTON HW MARKOSKI LJ STEINBAUGH BA TAIT BD LUNNEY EA TUMMINO PJ FERGUSON D HUPE D NOUHAN C GRACHECK SJ SAUNDERS JM VANDERROEST S
Citation: Se. Hagen et al., SYNTHESIS OF 5,6-DIHYDRO-4-HYDROXY-2-PYRONES AS HIV-1 PROTEASE INHIBITORS - THE PROFOUND EFFECT OF POLARITY ON ANTIVIRAL ACTIVITY, Journal of medicinal chemistry, 40(23), 1997, pp. 3707-3711
4-HYDROXY-5,6-DIHYDROPYRONES .2. POTENT NONPEPTIDE INHIBITORS OF HIV PROTEASE
Authors: TAIT BD HAGEN S DOMAGALA J ELLSWORTH EL GAJDA C HAMILTON HW PRASAD JVNV FERGUSON D GRAHAM N HUPE D NOUHAN C TUMMINO PJ HUMBLET C LUNNEY EA PAVLOVSKY A RUBIN J GRACHECK SJ BALDWIN ET BHAT TN ERICKSON JW GULNIK SV LIU BS
Citation: Bd. Tait et al., 4-HYDROXY-5,6-DIHYDROPYRONES .2. POTENT NONPEPTIDE INHIBITORS OF HIV PROTEASE, Journal of medicinal chemistry, 40(23), 1997, pp. 3781-3792
6-PHENYL-6-ALKYLAMIDO-5,6-DIHYDRO-2H-PYRAN-2-ONES - NOVEL HIV PROTEASE INHIBITORS
Authors: HAMILTON HW TAIT BD GAJDA C HAGEN SE FERGUSON D LUNNEY EA PAVLOVSKY A TUMMINO PJ
Citation: Hw. Hamilton et al., 6-PHENYL-6-ALKYLAMIDO-5,6-DIHYDRO-2H-PYRAN-2-ONES - NOVEL HIV PROTEASE INHIBITORS, Bioorganic & medicinal chemistry letters, 6(6), 1996, pp. 719-724
A TOPLISS TREE ANALYSIS OF THE HIV-PROTEASE INHIBITORY ACTIVITY OF 6-PHENYL-4-HYDROXY-PYRAN-2-ONES
Authors: STEINBAUGH BA HAMILTON HW PRASAD JVNV PARA KS TUMMINO PJ FERGUSON D LUNNEY EA BLANKLEY CJ
Citation: Ba. Steinbaugh et al., A TOPLISS TREE ANALYSIS OF THE HIV-PROTEASE INHIBITORY ACTIVITY OF 6-PHENYL-4-HYDROXY-PYRAN-2-ONES, Bioorganic & medicinal chemistry letters, 6(10), 1996, pp. 1099-1104
COMPARISON OF INTESTINAL PERMEABILITIES DETERMINED IN MULTIPLE IN-VITRO AND IN-SITU MODELS - RELATIONSHIP TO ABSORPTION IN HUMANS
Authors: STEWART BH CHAN OH LU RH REYNER EL SCHMID HL HAMILTON HW STEINBAUGH BA TAYLOR MD
Citation: Bh. Stewart et al., COMPARISON OF INTESTINAL PERMEABILITIES DETERMINED IN MULTIPLE IN-VITRO AND IN-SITU MODELS - RELATIONSHIP TO ABSORPTION IN HUMANS, Pharmaceutical research, 12(5), 1995, pp. 693-699
EVALUATION OF PHYSICOCHEMICAL PARAMETERS IMPORTANT TO THE ORAL BIOAVAILABILITY OF PEPTIDE-LIKE COMPOUNDS - IMPLICATIONS FOR THE SYNTHESIS OF RENIN INHIBITORS
Authors: HAMILTON HW STEINBAUGH BA STEWART BH CHAN OH SCHMID HL SCHROEDER R RYAN MJ KEISER J TAYLOR MD BLANKLEY CJ KALTENBRONN JS WRIGHT J HICKS J
Citation: Hw. Hamilton et al., EVALUATION OF PHYSICOCHEMICAL PARAMETERS IMPORTANT TO THE ORAL BIOAVAILABILITY OF PEPTIDE-LIKE COMPOUNDS - IMPLICATIONS FOR THE SYNTHESIS OF RENIN INHIBITORS, Journal of medicinal chemistry, 38(9), 1995, pp. 1446-1455
DESIGN AND SYNTHESIS OF RENIN INHIBITORS - INCORPORATION OF TRANSITION-STATE ISOSTERE SIDE-CHAINS THAT SPAN FROM THE S1 TO THE S3 BINDING POCKETS AND EXAMINATION OF P3-MODIFIED RENIN INHIBITORS
Authors: PLUMMER MS SHAHRIPOUR A KALTENBRONN JS LUNNEY EA STEINBAUGH BA HAMBY JM HAMILTON HW SAWYER TK HUMBLET C DOHERTY AM TAYLOR MD HINGORANI G BATLEY BL RAPUNDALO ST
Citation: Ms. Plummer et al., DESIGN AND SYNTHESIS OF RENIN INHIBITORS - INCORPORATION OF TRANSITION-STATE ISOSTERE SIDE-CHAINS THAT SPAN FROM THE S1 TO THE S3 BINDING POCKETS AND EXAMINATION OF P3-MODIFIED RENIN INHIBITORS, Journal of medicinal chemistry, 38(15), 1995, pp. 2893-2905
LOW-FRICTION ARTHROPLASTY AT 10 TO 20 YEARS - CONSEQUENCES OF PLASTICWEAR
Authors: HAMILTON HW GORCZYCA J
Citation: Hw. Hamilton et J. Gorczyca, LOW-FRICTION ARTHROPLASTY AT 10 TO 20 YEARS - CONSEQUENCES OF PLASTICWEAR, Clinical orthopaedics and related research, (318), 1995, pp. 160-166
TETRAHYDROISOQUINOLINE AS A PHENYLALANINE REPLACEMENT IN RENIN INHIBITORS
Authors: STEINBAUGH BA HAMILTON HW PATT WC RAPUNDALO ST BATLEY BL LUNNEY EA RYAN MJ HICKS GW
Citation: Ba. Steinbaugh et al., TETRAHYDROISOQUINOLINE AS A PHENYLALANINE REPLACEMENT IN RENIN INHIBITORS, Bioorganic & medicinal chemistry letters, 4(16), 1994, pp. 2029-2034
ANALYSES OF LIGAND-BINDING IN 5 ENDOTHIAPEPSIN CRYSTAL COMPLEXES AND THEIR USE IN THE DESIGN AND EVALUATION OF NOVEL RENIN INHIBITORS
Authors: LUNNEY EA HAMILTON HW HODGES JC KALTENBRONN JS REPINE JT BADASSO M COOPER JB DEALWIS C WALLACE BA LOWTHER WT DUNN BM HUMBLET C
Citation: Ea. Lunney et al., ANALYSES OF LIGAND-BINDING IN 5 ENDOTHIAPEPSIN CRYSTAL COMPLEXES AND THEIR USE IN THE DESIGN AND EVALUATION OF NOVEL RENIN INHIBITORS, Journal of medicinal chemistry, 36(24), 1993, pp. 3809-3820
PD 126,280 [ENDO(S) NORBORNYL-ADENOSINE], A HIGHLY SELECTIVE ADENOSINE-A1-RECEPTOR AGONIST, REDUCES INFARCT SIZE IN SWINE
Authors: MARTIN BJ MCCLANAHAN TB HAMILTON HW GALLAGHER KP
Citation: Bj. Martin et al., PD 126,280 [ENDO(S) NORBORNYL-ADENOSINE], A HIGHLY SELECTIVE ADENOSINE-A1-RECEPTOR AGONIST, REDUCES INFARCT SIZE IN SWINE, Circulation, 88(4), 1993, pp. 430-430
Risultati: 1-11 |