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Results: 1-18 |
Results: 18
A-PRIORI PREDICTION OF LIGAND AFFINITY BY ENERGY MINIMIZATION
Authors: HOLLOWAY MK
Citation: Mk. Holloway, A-PRIORI PREDICTION OF LIGAND AFFINITY BY ENERGY MINIMIZATION, Perspectives in drug discovery and design, 9-11, 1998, pp. 63-84
COMPLESTATIN TO CHLOROPEPTIN-I VIA A QUANTITATIVE ACID-CATALYZED REARRANGEMENT - ABSOLUTE STEREOCHEMICAL DETERMINATION OF COMPLESTATIN
Authors: JAYASURIYA H SALITURO GM SMITH SK HECK JV GOULD SJ SINGH SB HOMNICK CF HOLLOWAY MK PITZENBERGER SM PATANE MA
Citation: H. Jayasuriya et al., COMPLESTATIN TO CHLOROPEPTIN-I VIA A QUANTITATIVE ACID-CATALYZED REARRANGEMENT - ABSOLUTE STEREOCHEMICAL DETERMINATION OF COMPLESTATIN, Tetrahedron letters, 39(16), 1998, pp. 2247-2248
STRUCTURAL REQUIREMENTS AND CELL-TYPE SPECIFICITY FOR LIGAND ACTIVATION OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS
Authors: JOHNSON TE HOLLOWAY MK VOGEL R RUTLEDGE SJ PERKINS JJ RODAN GA SCHMIDT A
Citation: Te. Johnson et al., STRUCTURAL REQUIREMENTS AND CELL-TYPE SPECIFICITY FOR LIGAND ACTIVATION OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS, Journal of steroid biochemistry and molecular biology, 63(1-3), 1997, pp. 1-8
AN ORALLY BIOAVAILABLE PYRROLINONE INHIBITOR OF HIV-1 PROTEASE - COMPUTATIONAL ANALYSIS AND X-RAY CRYSTAL-STRUCTURE OF THE ENZYME COMPLEX
Authors: SMITH AB HIRSCHMANN R PASTERNAK A YAO WQ SPRENGELER PA HOLLOWAY MK KUO LC CHEN ZG DARKE PL SCHLEIF WA
Citation: Ab. Smith et al., AN ORALLY BIOAVAILABLE PYRROLINONE INHIBITOR OF HIV-1 PROTEASE - COMPUTATIONAL ANALYSIS AND X-RAY CRYSTAL-STRUCTURE OF THE ENZYME COMPLEX, Journal of medicinal chemistry, 40(16), 1997, pp. 2440-2444
A-PRIORI PREDICTION OF ACTIVITY FOR HIV-1 PROTEASE INHIBITORS EMPLOYING ENERGY MINIMIZATION IN THE ACTIVE-SITE (VOL 38, PG 308, 1995)
Authors: HOLLOWAY MK WAI JM HALGREN TA FITZGERALD PMD VACCA JP DORSEY BD LEVIN RB THOMPSON WJ CHEN LJ DESOLMS SJ GAFFIN N GHOSH AK GIULIANI EA GRAHAM SL GUARE JP HUNGATE RW LYLE TA SANDERS WM TUCKER TJ WIGGINS M WISCOUNT CM WOLTERSDORF OW YOUNG SD DARKE PL ZUGAY JA
Citation: Mk. Holloway et al., A-PRIORI PREDICTION OF ACTIVITY FOR HIV-1 PROTEASE INHIBITORS EMPLOYING ENERGY MINIMIZATION IN THE ACTIVE-SITE (VOL 38, PG 308, 1995), Journal of medicinal chemistry, 39(11), 1996, pp. 2280-2280
SYNTHESIS AND EVALUATION OF PYRIDYL ANALOGS OF L-735,524 - POTENT HIV-1 PROTEASE INHIBITORS (VOL 4, PG 2769, 1994)
Authors: DORSEY BD MCDANIEL SL LEVIN RB VACCA JP DARKE PL ZUGAY JA EMINI EA SCHLEIF WA LIN JH CHEN IW HOLLOWAY MK ANDERSON PS HUFF JR
Citation: Bd. Dorsey et al., SYNTHESIS AND EVALUATION OF PYRIDYL ANALOGS OF L-735,524 - POTENT HIV-1 PROTEASE INHIBITORS (VOL 4, PG 2769, 1994), Bioorganic & medicinal chemistry letters, 5(7), 1995, pp. 773-773
A-PRIORI PREDICTION OF ACTIVITY FOR HIV-1 PROTEASE INHIBITORS EMPLOYING ENERGY MINIMIZATION IN THE ACTIVE-SITE
Authors: HOLLOWAY MK WAI JM HALGREN TA FITZGERALD PMD VACCA JP DORSEY BD LEVIN RB THOMPSON WJ CHEN LJ DESOLMS SJ GAFFIN N GHOSH AK GIULIANI EA GRAHAM SL GUARE JP HUNGATE RW LYLE TA SANDERS WM TUCKER TJ WIGGINS M WISCOUNT CM WOLTERSDORF OW YOUNG SD DARKE PL ZUGAY JA
Citation: Mk. Holloway et al., A-PRIORI PREDICTION OF ACTIVITY FOR HIV-1 PROTEASE INHIBITORS EMPLOYING ENERGY MINIMIZATION IN THE ACTIVE-SITE, Journal of medicinal chemistry, 38(2), 1995, pp. 305-317
DESIGN AND SYNTHESIS OF NONPEPTIDE PEPTIDOMIMETIC INHIBITORS OF RENIN
Authors: SMITH AB AKAISHI R JONES DR KEENAN TP GUZMAN MC HOLCOMB RC SPRENGELER PA WOOD JL HIRSCHMANN R HOLLOWAY MK
Citation: Ab. Smith et al., DESIGN AND SYNTHESIS OF NONPEPTIDE PEPTIDOMIMETIC INHIBITORS OF RENIN, Biopolymers, 37(1), 1995, pp. 29-53
CONFORMATIONALLY CONSTRAINED HIV-1 PROTEASE INHIBITORS
Authors: VACCA JP FITZGERALD PMD HOLLOWAY MK HUNGATE RW STARBUCK KE CHEN LJ DARKE PL ANDERSON PS HUFF JR
Citation: Jp. Vacca et al., CONFORMATIONALLY CONSTRAINED HIV-1 PROTEASE INHIBITORS, Bioorganic & medicinal chemistry letters, 4(3), 1994, pp. 499-504
SYNTHESIS AND EVALUATION OF PYRIDYL ANALOGS OF L-735,524 - POTENT HIV-1 PROTEASE INHIBITORS
Authors: DORSEY BD MCDANIEL SL LEVIN RB VACCA JP DARKE PL ZUGAY JA EMINI EA SCHLEIF WA LIN JH CHEN IW HOLLOWAY MK ANDERSON PS HUFF JR
Citation: Bd. Dorsey et al., SYNTHESIS AND EVALUATION OF PYRIDYL ANALOGS OF L-735,524 - POTENT HIV-1 PROTEASE INHIBITORS, Bioorganic & medicinal chemistry letters, 4(23), 1994, pp. 2769-2774
NOVEL CONFORMATIONALLY CONSTRAINED HIV-1 PROTEASE INHIBITORS - RATIONAL DESIGN, ENZYME-INHIBITION, AND X-RAY STRUCTURE OF AN ENZYME-INHIBITOR COMPLEX
Authors: KIM BM VACCA JP FITZGERALD PMD DARKE PL HOLLOWAY MK GUARE JP HANIFIN CM ARFORDBICKERSTAFF DJ ZUGAY JA WAI JM ANDERSON PS HUFF JR
Citation: Bm. Kim et al., NOVEL CONFORMATIONALLY CONSTRAINED HIV-1 PROTEASE INHIBITORS - RATIONAL DESIGN, ENZYME-INHIBITION, AND X-RAY STRUCTURE OF AN ENZYME-INHIBITOR COMPLEX, Bioorganic & medicinal chemistry letters, 4(18), 1994, pp. 2199-2204
THE DESIGN AND SYNTHESIS OF ORALLY BIOAVAILABLE HIV-1 PROTEASE INHIBITORS
Authors: HUFF JR VACCA JP DORSEY BD THOMPSON WJ GHOSH AK HUNGATE RW LEE HY DARKE PL EMINI EA SCHLEIF WA LIN JH CHEN IW HOLLOWAY MK ANDERSON PS
Citation: Jr. Huff et al., THE DESIGN AND SYNTHESIS OF ORALLY BIOAVAILABLE HIV-1 PROTEASE INHIBITORS, Journal of cellular biochemistry, 1994, pp. 130-130
MUTATIONS IN HIV-1 PROTEASE RESIDUES AFFECTING SUSCEPTIBILITY TO L-735,524
Authors: CONDRA JH BLAHY OM BUSH BL CULBERSON C GOTLIB L GRAHAM DJ GRAHAM PL HOLLOWAY MK LAFEMINA RL QUINTERO JC RHODES A ROTH E SARDANA VV SCHNEIDER CL SCHLABACH AJ SCHLEIF WA TITUS DL WOLANSKI BS WOLFGANG JA EMINI EA
Citation: Jh. Condra et al., MUTATIONS IN HIV-1 PROTEASE RESIDUES AFFECTING SUSCEPTIBILITY TO L-735,524, Journal of cellular biochemistry, 1994, pp. 166-166
L-735,524 - AN ORALLY BIOAVAILABLE HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 PROTEASE INHIBITOR
Authors: VACCA JP DORSEY BD SCHLEIF WA LEVIN RB MCDANIEL SL DARKE PL ZUGAY J QUINTERO JC BLAHY OM ROTH E SARDANA VV SCHLABACH AJ GRAHAM PI CONDRA JH GOTLIB L HOLLOWAY MK LIN J CHEN IW VASTAG K OSTOVIC D ANDERSON PS EMINI EA HUFF JR
Citation: Jp. Vacca et al., L-735,524 - AN ORALLY BIOAVAILABLE HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 PROTEASE INHIBITOR, Proceedings of the National Academy of Sciences of the United Statesof America, 91(9), 1994, pp. 4096-4100
THE DEVELOPMENT OF CYCLIC SULFOLANES AS NOVEL AND HIGH-AFFINITY P(2) LIGANDS FOR HIV-1 PROTEASE INHIBITORS
Authors: GHOSH AK LEE HY THOMPSON WJ CULBERSON C HOLLOWAY MK MCKEE SP MUNSON PM DUONG TT SMITH AM DARKE PL ZUGAY JA EMINI EA SCHLEIF WA HUFF JR ANDERSON PS
Citation: Ak. Ghosh et al., THE DEVELOPMENT OF CYCLIC SULFOLANES AS NOVEL AND HIGH-AFFINITY P(2) LIGANDS FOR HIV-1 PROTEASE INHIBITORS, Journal of medicinal chemistry, 37(8), 1994, pp. 1177-1188
L-735,524 - THE DESIGN OF A POTENT AND ORALLY BIOAVAILABLE HIV PROTEASE INHIBITOR
Authors: DORSEY BD LEVIN RB MCDANIEL SL VACCA JP GUARE JP DARKE PL ZUGAY JA EMINI EA SCHLEIF WA QUINTERO JC LIN JH CHEN IW HOLLOWAY MK FITZGERALD PMD AXEL MG OSTOVIC D ANDERSON PS HUFF JR
Citation: Bd. Dorsey et al., L-735,524 - THE DESIGN OF A POTENT AND ORALLY BIOAVAILABLE HIV PROTEASE INHIBITOR, Journal of medicinal chemistry, 37(21), 1994, pp. 3443-3451
DESIGN AND SYNTHESIS OF PEPTIDOMIMETIC INHIBITORS OF HIV-1 PROTEASE AND RENIN - EVIDENCE FOR IMPROVED TRANSPORT
Authors: SMITH AB HIRSCHMANN R PASTERNAK A AKAISHI R GUZMAN MC JONES DR KEENAN TP SPRENGELER PA DARKE PL EMINI EA HOLLOWAY MK SCHLEIF WA
Citation: Ab. Smith et al., DESIGN AND SYNTHESIS OF PEPTIDOMIMETIC INHIBITORS OF HIV-1 PROTEASE AND RENIN - EVIDENCE FOR IMPROVED TRANSPORT, Journal of medicinal chemistry, 37(2), 1994, pp. 215-218
POTENT HIV PROTEASE INHIBITORS - THE DEVELOPMENT OF TETRAHYDROFURANYLGLYCINES AS NOVEL P(2)-LIGANDS AND PYRAZINE AMIDES AS P(3)-LIGANDS
Authors: GHOSH AK THOMPSON WJ HOLLOWAY MK MCKEE SP DUONG TT LEE HY MUNSON PM SMITH AM WAI JM DARKE PL ZUGAY JA EMINI EA SCHLEIF WA HUFF JR ANDERSON PS
Citation: Ak. Ghosh et al., POTENT HIV PROTEASE INHIBITORS - THE DEVELOPMENT OF TETRAHYDROFURANYLGLYCINES AS NOVEL P(2)-LIGANDS AND PYRAZINE AMIDES AS P(3)-LIGANDS, Journal of medicinal chemistry, 36(16), 1993, pp. 2300-2310
Risultati: 1-18 |