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Results: 1-16 |
Results: 16
Design and synthesis of novel scaffolds for drug discovery: Hybrids of beta-D-glucose with 1,2,3,4-tetrahydrobenzo[e][1,4]diazepin-5-one, the corresponding 1-oxazepine, and 2-and 4-pyridyldiazepines
Authors: Abrous, L Hynes, J Friedrich, SR Smith, AB Hirschmann, R
Citation: L. Abrous et al., Design and synthesis of novel scaffolds for drug discovery: Hybrids of beta-D-glucose with 1,2,3,4-tetrahydrobenzo[e][1,4]diazepin-5-one, the corresponding 1-oxazepine, and 2-and 4-pyridyldiazepines, ORG LETT, 3(7), 2001, pp. 1089-1092
First generation design, synthesis, and evaluation of azepine-based cryptophycin analogues
Authors: Smith, AB Cho, YS Zawacki, LE Hirschmann, R Pettit, GR
Citation: Ab. Smith et al., First generation design, synthesis, and evaluation of azepine-based cryptophycin analogues, ORG LETT, 3(25), 2001, pp. 4063-4066
Intramolecular hydrogen-bond participation in phosphonylammonium salt formation
Authors: Smith, AB Ducry, L Corbett, RM Hirschmann, R
Citation: Ab. Smith et al., Intramolecular hydrogen-bond participation in phosphonylammonium salt formation, ORG LETT, 2(24), 2000, pp. 3887-3890
A second generation synthesis of polypyrrolinone nonpeptidomimetics: Prelude to the synthesis of polypyrrolinones on solid support
Authors: Smith, AB Liu, H Hirschmann, R
Citation: Ab. Smith et al., A second generation synthesis of polypyrrolinone nonpeptidomimetics: Prelude to the synthesis of polypyrrolinones on solid support, ORG LETT, 2(14), 2000, pp. 2037-2040
Synthesis of polypyrrolinones on solid support
Authors: Smith, AB Liu, H Okumura, H Favor, DA Hirschmann, R
Citation: Ab. Smith et al., Synthesis of polypyrrolinones on solid support, ORG LETT, 2(14), 2000, pp. 2041-2044
Cyclic peptide formation catalyzed by an antibody ligase
Authors: Smithrud, DB Benkovic, PA Benkovic, SJ Roberts, V Liu, J Neagu, I Iwama, S Phillips, BW Smith, AB Hirschmann, R
Citation: Db. Smithrud et al., Cyclic peptide formation catalyzed by an antibody ligase, P NAS US, 97(5), 2000, pp. 1953-1958
Development of an efficient, regio- and stereoselective route to librariesbased on the beta-D-glucose scaffold
Authors: Hirschmann, R Ducry, L Smith, AB
Citation: R. Hirschmann et al., Development of an efficient, regio- and stereoselective route to librariesbased on the beta-D-glucose scaffold, J ORG CHEM, 65(24), 2000, pp. 8307-8316
Novel ligands lacking a positive charge for the delta- and mu-opioid receptors
Authors: Schiller, PW Berezowska, I Nguyen, TMD Schmidt, R Lemieux, C Chung, NN Falcone-Hindley, ML Yao, WQ Liu, J Iwama, S Smith, AB Hirschmann, R
Citation: Pw. Schiller et al., Novel ligands lacking a positive charge for the delta- and mu-opioid receptors, J MED CHEM, 43(4), 2000, pp. 551-559
Synthesis of a substance P antagonist with a somatostatin scaffold: Factors affecting agonism/antagonism at GPCRs and the role of pseudosymmetry
Authors: Liu, J Underwood, DJ Cascieri, MA Rohrer, SP Cantin, LD Chicchi, G Smith, AB Hirschmann, R
Citation: J. Liu et al., Synthesis of a substance P antagonist with a somatostatin scaffold: Factors affecting agonism/antagonism at GPCRs and the role of pseudosymmetry, J MED CHEM, 43(21), 2000, pp. 3827-3831
Design, synthesis, and solution structure of a pyrrolinone-based beta-turnpeptidomimetic
Authors: Smith, AB Wang, WY Sprengeler, PA Hirschmann, R
Citation: Ab. Smith et al., Design, synthesis, and solution structure of a pyrrolinone-based beta-turnpeptidomimetic, J AM CHEM S, 122(44), 2000, pp. 11037-11038
Molecular modeling, synthesis, and structures of N-methylated 3,5-linked pyrrolin-4-ones toward the creation of a privileged nonpeptide scaffold
Authors: Smith, AB Favor, DA Sprengeler, PA Guzman, MC Carroll, PJ Furst, GT Hirschmann, R
Citation: Ab. Smith et al., Molecular modeling, synthesis, and structures of N-methylated 3,5-linked pyrrolin-4-ones toward the creation of a privileged nonpeptide scaffold, BIO MED CH, 7(1), 1999, pp. 9-22
Azide and cyanide displacements via hypervalent silicate intermediates
Authors: Soli, ED Manoso, AS Patterson, MC DeShong, P Favor, DA Hirschmann, R Smith, AB
Citation: Ed. Soli et al., Azide and cyanide displacements via hypervalent silicate intermediates, J ORG CHEM, 64(9), 1999, pp. 3171-3177
Azide and cyanide displacements via hypervalent silicate intermediates (vol 65, pg 3171, 1998)
Authors: Soli, ED Manoso, AS Patterson, MC DeShong, P Favor, DA Hirschmann, R Smith, AB
Citation: Ed. Soli et al., Azide and cyanide displacements via hypervalent silicate intermediates (vol 65, pg 3171, 1998), J ORG CHEM, 64(17), 1999, pp. 6526-6526
Design and synthesis of a competent pyrrolinone-peptide hybrid ligand for the class II major histocompatibility complex protein HLA-DR1
Authors: Smith, AB Benowitz, AB Sprengeler, PA Barbosa, J Guzman, MC Hirschmann, R Schweiger, EJ Bolin, DR Nagy, Z Campbell, RM Cox, DC Olson, GL
Citation: Ab. Smith et al., Design and synthesis of a competent pyrrolinone-peptide hybrid ligand for the class II major histocompatibility complex protein HLA-DR1, J AM CHEM S, 121(40), 1999, pp. 9286-9298
Design and synthesis of a tetrahydropyran-based inhibitor of mammalian ribonucleotide reductase
Authors: Smith, AB Sasho, S Barwis, BA Sprengeler, P Barbosa, J Hirschmann, R Cooperman, BS
Citation: Ab. Smith et al., Design and synthesis of a tetrahydropyran-based inhibitor of mammalian ribonucleotide reductase, BIOORG MED, 8(22), 1998, pp. 3133-3136
Design, synthesis, and evaluation of a pyrrolinone-peptide hybrid ligand for the class II MHC protein HLA-DR1
Authors: Smith, AB Benowitz, AB Guzman, MC Sprengeler, PA Hirschmann, R Schweiger, EJ Bolin, DR Nagy, Z Campbell, RM Cox, DC Olson, GL
Citation: Ab. Smith et al., Design, synthesis, and evaluation of a pyrrolinone-peptide hybrid ligand for the class II MHC protein HLA-DR1, J AM CHEM S, 120(48), 1998, pp. 12704-12705
Risultati: 1-16 |