Authors:
McIntyre, BG
Bermejo, FM
Srivastava, SK
Husbands, SM
Lewis, JW
Crosby, J
Simpson, TJ
Citation: Bg. Mcintyre et al., Solid phase synthesis of 4-hydroxycinnamic acid and its derivatives for potential use in combinatorial chemistry: A novel route for the synthesis of 4-hydroxycinnamoyl coenzyme A and NMDA receptor antagonists, COMB CHEM H, 4(1), 2001, pp. 111-114
Authors:
Cao, JJ
Husbands, SM
Kopajtic, T
Katz, JL
Newman, AH
Citation: Jj. Cao et al., [3-cis-3,5-dimethyl-(1-piperazinyl)alkyl]-bis-(4 '-fluorophenyl)amine analogues as novel probes for the dopamine transporter, BIOORG MED, 11(24), 2001, pp. 3169-3173
Authors:
Matsumoto, RR
Hewett, KL
Pouw, B
Bowen, WD
Husbands, SM
Cao, JJ
Newman, AH
Citation: Rr. Matsumoto et al., Rimcazole analogs attenuate the convulsive effects of cocaine: correlationwith binding to sigma receptors rather than dopamine transporters, NEUROPHARM, 41(7), 2001, pp. 878-886
Authors:
Robarge, MJ
Husbands, SM
Kieltyka, A
Brodbeck, R
Thurkauf, A
Newman, AH
Citation: Mj. Robarge et al., Design and synthesis of [(2,3-dichlorophenyl)piperazin-1-yl]alkylfluorenylcarboxamides as novel ligands selective for the dopamine D-3 receptor subtype, J MED CHEM, 44(19), 2001, pp. 3175-3186
Authors:
Coates, PA
Grundt, P
Robinson, ESJ
Nutt, DJ
Tyacke, R
Hudson, AL
Lewis, JW
Husbands, SM
Citation: Pa. Coates et al., Probes for imidazoline binding sites: Synthesis and evaluation of a selective, irreversible I-2 ligand, BIOORG MED, 10(6), 2000, pp. 605-607
Citation: Ar. Jales et al., Selective kappa-opioid antagonists related to naltrindole. Effect of side-chain spacer in the 5 '-amidinoalkyl series, BIOORG MED, 10(20), 2000, pp. 2259-2261
Authors:
Derrick, I
Coop, A
Al-Mousawi, SM
Husbands, SM
Lewis, JW
Citation: I. Derrick et al., Perchloric acid induced epimerisation of the thevinones: an improved synthesis of 7 beta-dihydrothevinones, TETRAHEDR L, 41(39), 2000, pp. 7571-7576
Authors:
Broadbear, JH
Sumpter, TL
Burke, TF
Husbands, SM
Lewis, JW
Woods, JH
Traynor, JR
Citation: Jh. Broadbear et al., Methocinnamox is a potent, long-lasting, and selective antagonist of morphine-mediated antinociception in the mouse: Comparison with clocinnamox, beta-funaltrexamine, and beta-chlornaltrexamine, J PHARM EXP, 294(3), 2000, pp. 933-940
Authors:
Broom, DC
Guo, L
Coop, A
Husbands, SM
Lewis, JW
Woods, JH
Traynor, JR
Citation: Dc. Broom et al., BU48: A novel buprenorphine analog that exhibits delta-opioid-mediated convulsions but not delta-opioid-mediated antinociception in mice, J PHARM EXP, 294(3), 2000, pp. 1195-1200
Authors:
Coop, A
Norton, CL
Berzetei-Gurske, I
Burnside, J
Toll, L
Husbands, SM
Lewis, JW
Citation: A. Coop et al., Structural determinants of opioid activity in the orvinols and related structures: Ethers of orvinol and isoorvinol, J MED CHEM, 43(9), 2000, pp. 1852-1857
Citation: Sm. Husbands et Jw. Lewis, Structural determinants of efficacy for kappa opioid receptors in the orvinol series: 7,7-spiro analogues of buprenorphine, J MED CHEM, 43(2), 2000, pp. 139-141
Authors:
Derrick, I
Neilan, CL
Andes, J
Husbands, SM
Woods, JH
Traynor, JR
Lewis, JW
Citation: I. Derrick et al., 3-deoxyclocinnamox: The first high-affinity, nonpeptide mu-opioid antagonist lacking a phenolic hydroxyl group, J MED CHEM, 43(17), 2000, pp. 3348-3350
Authors:
Coop, A
Berzetei-Gurske, I
Burnside, J
Toll, L
Traynor, JR
Husbands, SM
Lewis, JW
Citation: A. Coop et al., Structural determinants of opioid activity in the orvinols and related structures. Ethers of 7,8-cyclopenta-fused analogs of buprenorphine, HELV CHIM A, 83(4), 2000, pp. 687-693
Authors:
Derrick, I
Husbands, SM
Broadbear, J
Traynor, JR
Woods, JH
Lewis, JW
Citation: I. Derrick et al., Cinnamoyl derivatives of 7 alpha-amino- and 7 alpha-(aminomethyl)-N-(cyclopropylmethyl)-6,14-endo-ethanotetrahydronororipavines are high-potency opioid antagonists, HELV CHIM A, 83(12), 2000, pp. 3122-3130
Authors:
Grivas, K
Breeden, SW
Ganter, C
Husbands, SM
Lewis, JW
Citation: K. Grivas et al., Acid catalysed rearrangements of the thevinols: The mechanism of furanocodide formation., TETRAHEDR L, 40(9), 1999, pp. 1795-1798
Authors:
Husbands, SM
Izenwasser, S
Kopajtic, T
Bowen, WD
Vilner, BJ
Katz, JL
Newman, AH
Citation: Sm. Husbands et al., Structure-activity relationships at the monoamine transporters and a receptors for a novel series of 9-[3-(cis-3,5-dimethyl-1-piperazinyl)-propyl]carbazole (rimcazole) analogues, J MED CHEM, 42(21), 1999, pp. 4446-4455
Authors:
Breeden, SW
Coop, A
Husbands, SM
Lewis, JW
Citation: Sw. Breeden et al., 6-O-demethylation of the thevinols with lithium aluminium hydride: Selective demethylation of a tertiary alkyl methyl ether in the presence of an aryl methyl ether, HELV CHIM A, 82(11), 1999, pp. 1978-1980
Citation: Fm. Bermejo et al., Derivatives of flavonepenthone: Kappa opioid receptor selectivity in an N-methylmorphinan, HELV CHIM A, 82(10), 1999, pp. 1721-1727