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Results: 1-10 |
Results: 10
NONPEPTIDIC HIV PROTEASE INHIBITORS - C-2-SYMMETRY-BASED DESIGN OF BIS-SULFONAMIDE DIHYDROPYRONES
Authors: JANAKIRAMAN MN WATENPAUGH KD TOMICH PK CHONG KT TURNER SR TOMMASI RA THAISRIVONGS S STROHBACH JW
Citation: Mn. Janakiraman et al., NONPEPTIDIC HIV PROTEASE INHIBITORS - C-2-SYMMETRY-BASED DESIGN OF BIS-SULFONAMIDE DIHYDROPYRONES, Bioorganic & medicinal chemistry letters, 8(10), 1998, pp. 1237-1242
TIPRANAVIR (PNU-140690) - A POTENT, ORALLY BIOAVAILABLE NONPEPTIDIC HIV PROTEASE INHIBITOR OF THE 5,6-DIHYDRO-4-HYDROXY-2-PYRONE SULFONAMIDE CLASS
Authors: TURNER SR STROHBACH JW TOMMASI RA ARISTOFF PA JOHNSON PD SKULNICK HI DOLAK LA SEEST EP TOMICH PK BOHANAN MJ HORNG MM LYNN JC CHONG KT HINSHAW RR WATENPAUGH KD JANAKIRAMAN MN THAISRIVONGS S
Citation: Sr. Turner et al., TIPRANAVIR (PNU-140690) - A POTENT, ORALLY BIOAVAILABLE NONPEPTIDIC HIV PROTEASE INHIBITOR OF THE 5,6-DIHYDRO-4-HYDROXY-2-PYRONE SULFONAMIDE CLASS, Journal of medicinal chemistry, 41(18), 1998, pp. 3467-3476
STRUCTURE-BASED DESIGN OF NONPEPTIDIC HIV PROTEASE INHIBITORS - THE SULFONAMIDE-SUBSTITUTED CYCLOOCTYLPYRANONES
Authors: SKULNICK HI JOHNSON PD ARISTOFF PA MORRIS JK LOVASZ KD HOWE WJ WATENPAUGH KD JANAKIRAMAN MN ANDERSON DJ REISCHER RJ SCHWARTZ TM BANITT LS TOMICH PK LYNN JC HORNG MM CHONG KT HINSHAW RR DOLAK LA SEEST EP SCHWENDE FJ RUSH BD HOWARD GM TOTH LN WILKINSON KR KAKUK TJ JOHNSON CW COLE SL ZAYA RM ZIPP GL POSSERT PL DALGA RJ ZHONG WZ WILLIAMS MG ROMINES KR
Citation: Hi. Skulnick et al., STRUCTURE-BASED DESIGN OF NONPEPTIDIC HIV PROTEASE INHIBITORS - THE SULFONAMIDE-SUBSTITUTED CYCLOOCTYLPYRANONES, Journal of medicinal chemistry, 40(7), 1997, pp. 1149-1164
STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - 5,6-DIHYDRO-4-HYDROXY-2-PYRONES AS EFFECTIVE, NONPEPTIDIC INHIBITORS
Authors: THAISRIVONGS S ROMERO DL TOMMASI RA JANAKIRAMAN MN STROHBACH JW TURNER SR BILES C MORGE RR JOHNSON PD ARISTOFF PA TOMICH PK LYNN JC HORNG MM CHONG KT HINSHAW RR HOWE WJ FINZEL BC WATENPAUGH KD
Citation: S. Thaisrivongs et al., STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - 5,6-DIHYDRO-4-HYDROXY-2-PYRONES AS EFFECTIVE, NONPEPTIDIC INHIBITORS, Journal of medicinal chemistry, 39(23), 1996, pp. 4630-4642
STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - SULFONAMIDE-CONTAINING 5,6-DIHYDRO-4-HYDROXY-2-PYRONES AS NONPEPTIDIC INHIBITORS
Authors: THAISRIVONGS S SKULNICK HI TURNER SR STROHBACH JW TOMMASI RA JOHNSON PD ARISTOFF PA JUDGE TM GAMMILL RB MORRIS JK ROMINES KR CHRUSCIEL RA HINSHAW RR CHONG KT TARPLEY WG POPPE SM SLADE DE LYNN JC HORNG MM TOMICH PK SEEST EP DOLAK LA HOWE WJ HOWARD GM SCHWENDE FJ TOTH LN PADBURY GE WILSON GJ SHIOU LH ZIPP GL WILKINSON KF RUSH BD RUWART MJ KOEPLINGER KA ZHAO ZY COLE S ZAYA RM KAKUK TJ JANAKIRAMAN MN WATENPAUGH KD
Citation: S. Thaisrivongs et al., STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - SULFONAMIDE-CONTAINING 5,6-DIHYDRO-4-HYDROXY-2-PYRONES AS NONPEPTIDIC INHIBITORS, Journal of medicinal chemistry, 39(22), 1996, pp. 4349-4353
A SIALIC ACID-DERIVED PHOSPHONATE ANALOG INHIBITS DIFFERENT STRAINS OF INFLUENZA-VIRUS NEURAMINIDASE WITH DIFFERENT EFFICIENCIES
Authors: WHITE CL JANAKIRAMAN MN LAVER WG PHILIPPON C VASELLA A AIR GM LUO M
Citation: Cl. White et al., A SIALIC ACID-DERIVED PHOSPHONATE ANALOG INHIBITS DIFFERENT STRAINS OF INFLUENZA-VIRUS NEURAMINIDASE WITH DIFFERENT EFFICIENCIES, Journal of Molecular Biology, 245(5), 1995, pp. 623-634
STRUCTURE-BASED DESIGN OF SULFONAMIDE-SUBSTITUTED NONPEPTIDIC HIV PROTEASE INHIBITORS
Authors: SKULNICK HI JOHNSON PD HOWE WJ TOMICH PK CHONG KT WATENPAUGH KD JANAKIRAMAN MN DOLAK LA MCGRATH JP LYNN JC HORNG MM HINSHAW RR ZIPP GL RUWART MJ SCHWENDE FJ ZHONG WZ PADBURY GE DALGA RJ SHIOU LH POSSERT PL RUSH BD WILKINSON KF HOWARD GM TOTH LN WILLIAMS MG KAKUK TJ COLE SL ZAYA RM LOVASZ KD MORRIS JK ROMINES KR THAISRIVONGS S ARISTOFF PA
Citation: Hi. Skulnick et al., STRUCTURE-BASED DESIGN OF SULFONAMIDE-SUBSTITUTED NONPEPTIDIC HIV PROTEASE INHIBITORS, Journal of medicinal chemistry, 38(26), 1995, pp. 4968-4971
STRUCTURE-BASED DESIGN OF NONPEPTIDIC HIV PROTEASE INHIBITORS FROM A CYCLOOCTYLPYRANONE LEAD STRUCTURE
Authors: ROMINES KR WATENPAUGH KD HOWE WJ TOMICH PK LOVASZ KD MORRIS JK JANAKIRAMAN MN LYNN JC HORNG MM CHONG KT HINSHAW RR DOLAK LA
Citation: Kr. Romines et al., STRUCTURE-BASED DESIGN OF NONPEPTIDIC HIV PROTEASE INHIBITORS FROM A CYCLOOCTYLPYRANONE LEAD STRUCTURE, Journal of medicinal chemistry, 38(22), 1995, pp. 4463-4473
STRUCTURE-BASED DESIGN OF NOVEL HIV PROTEASE INHIBITORS - CARBOXAMIDE-CONTAINING 4-HYDROXYCOUMARINS AND 4-HYDROXY-2-PYRONES AS POTENT NONPEPTIDIC INHIBITORS
Authors: THAISRIVONGS S WATENPAUGH KD HOWE WJ TOMICH PK DOLAK LA CHONG KT TOMICH CSC TOMASSELLI AG TURNER SR STROHBACH JW MULICHAK AM JANAKIRAMAN MN MOON JB LYNN JC HORNG MM HINSHAW RR CURRY KA ROTHROCK DJ
Citation: S. Thaisrivongs et al., STRUCTURE-BASED DESIGN OF NOVEL HIV PROTEASE INHIBITORS - CARBOXAMIDE-CONTAINING 4-HYDROXYCOUMARINS AND 4-HYDROXY-2-PYRONES AS POTENT NONPEPTIDIC INHIBITORS, Journal of medicinal chemistry, 38(18), 1995, pp. 3624-3637
STRUCTURE OF INFLUENZA-VIRUS NEURAMINIDASE B LEE/40 COMPLEXED WITH SIALIC-ACID AND A DEHYDRO ANALOG AT 1.8-ANGSTROM RESOLUTION - IMPLICATIONS FOR THE CATALYTIC MECHANISM/
Authors: JANAKIRAMAN MN WHITE CL LAVER WG AIR GM LUO M
Citation: Mn. Janakiraman et al., STRUCTURE OF INFLUENZA-VIRUS NEURAMINIDASE B LEE/40 COMPLEXED WITH SIALIC-ACID AND A DEHYDRO ANALOG AT 1.8-ANGSTROM RESOLUTION - IMPLICATIONS FOR THE CATALYTIC MECHANISM/, Biochemistry, 33(27), 1994, pp. 8172-8179
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