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Results: 1-25 | 26-45
Results: 1-25/45
INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS - SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF NOVEL SERIES OF SULFONAMIDES, ACYLPHOSPHONAMIDES AND ACYLPHOSPHORAMIDATES
Authors: LEE HT ROARK WH PICARD JA SLISKOVIC DR ROTH BD STANFIELD RL HAMELEHLE KL BOUSLEY RF KRAUSE BR
Citation: Ht. Lee et al., INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS - SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF NOVEL SERIES OF SULFONAMIDES, ACYLPHOSPHONAMIDES AND ACYLPHOSPHORAMIDATES, Bioorganic & medicinal chemistry letters, 8(3), 1998, pp. 289-294
LIPID-LOWERING EFFECTS OF WAY-121,898, AN INHIBITOR OF PANCREATIC CHOLESTERYL ESTER HYDROLASE
Authors: KRAUSE BR SLISKOVIC DR ANDERSON M HOMAN R
Citation: Br. Krause et al., LIPID-LOWERING EFFECTS OF WAY-121,898, AN INHIBITOR OF PANCREATIC CHOLESTERYL ESTER HYDROLASE, Lipids, 33(5), 1998, pp. 489-498
ALPHA-SUBSTITUTED MALONESTER AMIDES - TOOLS TO DEFINE THE RELATIONSHIP BETWEEN ACAT INHIBITION AND ADRENAL TOXICITY
Authors: SLISKOVIC DR PICARD JA OBRIEN PM LIAO P ROARK WH ROTH BD ANDERSON MA MUELLER SB BOCAN TMA BOUSLEY RF HAMELEHLE KL HOMAN R REINDEL JF STANFIELD RL TURLUCK D KRAUSE BR
Citation: Dr. Sliskovic et al., ALPHA-SUBSTITUTED MALONESTER AMIDES - TOOLS TO DEFINE THE RELATIONSHIP BETWEEN ACAT INHIBITION AND ADRENAL TOXICITY, Journal of medicinal chemistry, 41(5), 1998, pp. 682-690
ACAT-2, A 2ND MAMMALIAN ACYL-COA-CHOLESTEROL ACYLTRANSFERASE - ITS CLONING, EXPRESSION, AND CHARACTERIZATION
Authors: CASES S NOVAK S ZHENG YW MYERS HM LEAR SR SANDE E WELCH CB LUSIS AJ SPENCER TA KRAUSE BR ERICKSON SK FARESE RV
Citation: S. Cases et al., ACAT-2, A 2ND MAMMALIAN ACYL-COA-CHOLESTEROL ACYLTRANSFERASE - ITS CLONING, EXPRESSION, AND CHARACTERIZATION, The Journal of biological chemistry, 273(41), 1998, pp. 26755-26764
LACK OF PREDICTABILITY OF CLASSICAL ANIMAL-MODELS FOR HYPOLIPIDEMIC ACTIVITY - A GOOD TIME FOR MICE
Authors: KRAUSE BR PRINCEN HMG
Citation: Br. Krause et Hmg. Princen, LACK OF PREDICTABILITY OF CLASSICAL ANIMAL-MODELS FOR HYPOLIPIDEMIC ACTIVITY - A GOOD TIME FOR MICE, Atherosclerosis (Amsterdam), 140(1), 1998, pp. 15-24
THE ACAT INHIBITOR, CI-1011 IS EFFECTIVE IN THE PREVENTION AND REGRESSION OF AORTIC FATTY STREAK AREA IN HAMSTERS
Authors: NICOLOSI RJ WILSON TA KRAUSE BR
Citation: Rj. Nicolosi et al., THE ACAT INHIBITOR, CI-1011 IS EFFECTIVE IN THE PREVENTION AND REGRESSION OF AORTIC FATTY STREAK AREA IN HAMSTERS, Atherosclerosis, 137(1), 1998, pp. 77-85
HYPERCHOLESTEROLEMIA-INDUCED WEAKENING OF RABBIT ATHEROSCLEROTIC PLAQUES IS ASSOCIATED WITH ALTERATIONS IN COLLAGEN TURNOVER
Authors: REKHTER MD HICKS GW BRAMMER D KUIPERS PJ ROSEBURY WS GORDON D KRAUSE BR HOMAN R RYAN MJ
Citation: Md. Rekhter et al., HYPERCHOLESTEROLEMIA-INDUCED WEAKENING OF RABBIT ATHEROSCLEROTIC PLAQUES IS ASSOCIATED WITH ALTERATIONS IN COLLAGEN TURNOVER, Circulation, 98(17), 1998, pp. 237-237
INHIBITORS OF ACYL-COA-CHOLESTEROL ACYLTRANSFERASE - NOVEL TRISUBSTITUTED UREAS AS HYPOCHOLESTEROLEMIC AGENTS
Authors: PURCHASE TS ESSENBURG AD HAMELEHLE KL HES MS HOLMES A KRAUSE BR STANFIELD RL TRIVEDI BK
Citation: Ts. Purchase et al., INHIBITORS OF ACYL-COA-CHOLESTEROL ACYLTRANSFERASE - NOVEL TRISUBSTITUTED UREAS AS HYPOCHOLESTEROLEMIC AGENTS, Bioorganic & medicinal chemistry, 5(4), 1997, pp. 739-747
ACAT INHIBITION BY CI-1011 LOWERS PLASMA TRIGLYCERIDES IN RATS BY ENHANCING THE CLEARANCE OF VLDL
Authors: KRAUSE BR AUERBACH BJ
Citation: Br. Krause et Bj. Auerbach, ACAT INHIBITION BY CI-1011 LOWERS PLASMA TRIGLYCERIDES IN RATS BY ENHANCING THE CLEARANCE OF VLDL, Atherosclerosis, 134(1-2), 1997, pp. 128-128
RABBITS FED COCONUT OIL DISPLAY ELEVATED HEPATIC APOLIPOPROTEIN-A-I TRANSCRIPTION
Authors: SCHWAB DA REA TJ HANSELMAN JC KRAUSE BR PAPE ME
Citation: Da. Schwab et al., RABBITS FED COCONUT OIL DISPLAY ELEVATED HEPATIC APOLIPOPROTEIN-A-I TRANSCRIPTION, Molecular biology of the cell, 7, 1996, pp. 3620-3620
INHIBITORS OF ACYL-COA - CHOLESTEROL O-ACYL TRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS - THE SYNTHESIS AND BIOLOGICAL-ACTIVITY OF A SERIES OF MALONESTER AMIDES
Authors: SLISKOVIC DR PICARD JA ROARK WH ESSENBURG AD KRAUSE BR MINTON LL REINDEL JF STANFIELD RL
Citation: Dr. Sliskovic et al., INHIBITORS OF ACYL-COA - CHOLESTEROL O-ACYL TRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS - THE SYNTHESIS AND BIOLOGICAL-ACTIVITY OF A SERIES OF MALONESTER AMIDES, Bioorganic & medicinal chemistry letters, 6(6), 1996, pp. 713-718
TETRAZOLE-SUBSTITUTED UREAS AS INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE (ACAT) - A NOVEL PREPARATION OF UREAS FROM WEAKLY NUCLEOPHILIC AMINES
Authors: PURCHASE CF WHITE AD ANDERSON MK BOCAN TMA BOUSLEY RF HAMELEHLE KL HOMAN R KRAUSE BR LEE P MUELLER SB SPEYER C STANFIELD RL REINDEL JF
Citation: Cf. Purchase et al., TETRAZOLE-SUBSTITUTED UREAS AS INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE (ACAT) - A NOVEL PREPARATION OF UREAS FROM WEAKLY NUCLEOPHILIC AMINES, Bioorganic & medicinal chemistry letters, 6(15), 1996, pp. 1753-1758
THE ACAT INHIBITOR, CI-1011 IS EFFECTIVE IN THE PREVENTION AND REGRESSION OF ATHEROGENESIS IN HAMSTERS
Authors: LAITINEN L NICOLOSI RJ KRAUSE BR
Citation: L. Laitinen et al., THE ACAT INHIBITOR, CI-1011 IS EFFECTIVE IN THE PREVENTION AND REGRESSION OF ATHEROGENESIS IN HAMSTERS, The FASEB journal, 10(3), 1996, pp. 2943-2943
INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE .17. STRUCTURE-ACTIVITY-RELATIONSHIPS OF SEVERAL SERIES OF COMPOUNDS DERIVED FROM N-CHLOROSULFONYL ISOCYANATE
Authors: PICARD JA OBRIEN PM SLISKOVIC DR ANDERSON MK BOUSLEY RF HAMELEHLE KL KRAUSE BR STANFIELD RL
Citation: Ja. Picard et al., INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE .17. STRUCTURE-ACTIVITY-RELATIONSHIPS OF SEVERAL SERIES OF COMPOUNDS DERIVED FROM N-CHLOROSULFONYL ISOCYANATE, Journal of medicinal chemistry, 39(6), 1996, pp. 1243-1252
INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS - CI-1011 - AN ACYL SULFAMATE WITH UNIQUE CHOLESTEROL-LOWERING ACTIVITY IN ANIMALS FED NONCHOLESTEROL-SUPPLEMENTED DIETS
Authors: LEE HT SLISKOVIC DR PICARD JA ROTH BD WIERENGA W HICKS JL BOUSLEY RF HAMELEHLE KL HOMAN R SPEYER C STANFIELD RL KRAUSE BR
Citation: Ht. Lee et al., INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS - CI-1011 - AN ACYL SULFAMATE WITH UNIQUE CHOLESTEROL-LOWERING ACTIVITY IN ANIMALS FED NONCHOLESTEROL-SUPPLEMENTED DIETS, Journal of medicinal chemistry, 39(26), 1996, pp. 5031-5034
HETEROCYCLIC UREAS - INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE AS HYPOCHOLESTEROLEMIC AGENTS
Authors: WHITE AD CRESWELL MW CHUCHOLOWSKI AW BLANKLEY CJ WILSON MW BOUSLEY RF ESSENBURG AD HAMELEHLE KL KRAUSE BR STANFIELD RL DOMINICK MA NEUB M
Citation: Ad. White et al., HETEROCYCLIC UREAS - INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE AS HYPOCHOLESTEROLEMIC AGENTS, Journal of medicinal chemistry, 39(22), 1996, pp. 4382-4395
HETEROCYCLIC AMIDES - INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE WITH HYPOCHOLESTEROLEMIC ACTIVITY IN SEVERAL SPECIES AND ANTIATHEROSCLEROTIC ACTIVITY IN THE RABBIT
Authors: WHITE AD PURCHASE CF PICARD JA ANDERSON MK MUELLER SB BOCAN TMA BOUSLEY RF HAMELEHLE KL KRAUSE BR LEE P STANFIELD RL REINDEL JF
Citation: Ad. White et al., HETEROCYCLIC AMIDES - INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE WITH HYPOCHOLESTEROLEMIC ACTIVITY IN SEVERAL SPECIES AND ANTIATHEROSCLEROTIC ACTIVITY IN THE RABBIT, Journal of medicinal chemistry, 39(20), 1996, pp. 3908-3919
HYPOCHOLESTEROLEMIC ACTIONS OF ATORVASTATIN ARE ASSOCIATED WITH ALTERATIONS ON HEPATIC CHOLESTEROL-METABOLISM AND LIPOPROTEIN COMPOSITION IN THE GUINEA-PIG
Authors: CONDE K VERGARAJIMENEZ M KRAUSE BR NEWTON RS FERNANDEZ ML
Citation: K. Conde et al., HYPOCHOLESTEROLEMIC ACTIONS OF ATORVASTATIN ARE ASSOCIATED WITH ALTERATIONS ON HEPATIC CHOLESTEROL-METABOLISM AND LIPOPROTEIN COMPOSITION IN THE GUINEA-PIG, Journal of lipid research, 37(11), 1996, pp. 2372-2382
OPPOSITE EFFECTS OF BEZAFIBRATE AND GEMFIBROZIL IN BOTH NORMAL AND HYPERTRIGLYCERIDEMIC RATS
Authors: KRAUSE BR BARNETT BC ESSENBURG AD KIEFT KA AUERBACH BJ BOUSLEY R STANFIELD R NEWTON RS BISGAIER CL
Citation: Br. Krause et al., OPPOSITE EFFECTS OF BEZAFIBRATE AND GEMFIBROZIL IN BOTH NORMAL AND HYPERTRIGLYCERIDEMIC RATS, Atherosclerosis, 127(1), 1996, pp. 91-101
HIGH CORRELATION BUT LACK OF AGREEMENT BETWEEN DIRECT HIGH-PERFORMANCE GEL CHROMATOGRAPHY ANALYSIS AND CONVENTIONAL INDIRECT METHODS FOR DETERMINING LIPOPROTEIN CHOLESTEROL
Authors: KRAUSE BR SCHORK NJ KIEFT KA SMITH MP MACIEJKO JJ
Citation: Br. Krause et al., HIGH CORRELATION BUT LACK OF AGREEMENT BETWEEN DIRECT HIGH-PERFORMANCE GEL CHROMATOGRAPHY ANALYSIS AND CONVENTIONAL INDIRECT METHODS FOR DETERMINING LIPOPROTEIN CHOLESTEROL, Clinical chemistry, 42(12), 1996, pp. 1996-2001
INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS .12. SYNTHESES AND BIOLOGICAL-ACTIVITY OF STRUCTURALLY NOVEL TETRAZOLE AMIDES
Authors: OBRIEN PM SLISKOVIC DR ANDERSON MK BOUSLEY RF KRAUSE BR STANFIELD RL
Citation: Pm. Obrien et al., INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS .12. SYNTHESES AND BIOLOGICAL-ACTIVITY OF STRUCTURALLY NOVEL TETRAZOLE AMIDES, Bioorganic & medicinal chemistry letters, 5(3), 1995, pp. 289-294
INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS .13. DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATIONOF TETRAZOLE ANILIDES AS POTENT INHIBITORS OF ACAT IN-VITRO AND HYPOCHOLESTEROLEMIC AGENTS IN-VITRO
Authors: OBRIEN PM SLISKOVIC DR BERNABEI A HURLEY T ANDERSON MK BOUSLEY RF KRAUSE BR STANFIELD RL
Citation: Pm. Obrien et al., INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS .13. DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATIONOF TETRAZOLE ANILIDES AS POTENT INHIBITORS OF ACAT IN-VITRO AND HYPOCHOLESTEROLEMIC AGENTS IN-VITRO, Bioorganic & medicinal chemistry letters, 5(3), 1995, pp. 295-300
INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS .14. SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF A NOVEL SERIES OF SULFONAMIDE TETRAZOLES
Authors: LEE HT SLISKOVIC DR STANFIELD RL HAMELEHLE KL BOUSLEY RF KRAUSE BR
Citation: Ht. Lee et al., INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS .14. SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF A NOVEL SERIES OF SULFONAMIDE TETRAZOLES, Bioorganic & medicinal chemistry letters, 5(3), 1995, pp. 301-306
INHIBITORS OF ACYL-COA-CHOLESTEROL ACYLTRANSFERASE (ACAT) .15. SULFONYLUREA INHIBITORS WITH EXCELLENT HYPOCHOLESTEROLEMIC ACTIVITY IN-VIVO
Authors: ROTH BD ROARK WH PICARD JA STANFIELD RL BOUSLEY RF ANDERSON MK HAMELEHLE KL HOMAN R KRAUSE BR
Citation: Bd. Roth et al., INHIBITORS OF ACYL-COA-CHOLESTEROL ACYLTRANSFERASE (ACAT) .15. SULFONYLUREA INHIBITORS WITH EXCELLENT HYPOCHOLESTEROLEMIC ACTIVITY IN-VIVO, Bioorganic & medicinal chemistry letters, 5(20), 1995, pp. 2367-2370
A SERIES OF CONFORMATIONALLY AND STERICALLY CONSTRAINED ANALOGS OF N-PHENYL-N'-ARALKYLUREA ACAT INHIBITORS
Authors: TRIVEDI BK HOLMES A PURCHASE TS ESSENBURG AD HAMELEHLE KL KRAUSE BR HES MS STANFIELD RL
Citation: Bk. Trivedi et al., A SERIES OF CONFORMATIONALLY AND STERICALLY CONSTRAINED ANALOGS OF N-PHENYL-N'-ARALKYLUREA ACAT INHIBITORS, Bioorganic & medicinal chemistry letters, 5(19), 1995, pp. 2229-2234
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