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Results: 1-13 |
Results: 13
THE DESIGN OF POTENT AND STABLE BENZISOTHIAZOLONE INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE
Authors: HLASTA DJ BELL MR COURT JJ CUNDY KC DESAI RC FERGUSON EW GORDON RJ KUMAR V MAYCOCK AL SUBRAMANYAM C
Citation: Dj. Hlasta et al., THE DESIGN OF POTENT AND STABLE BENZISOTHIAZOLONE INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE, Bioorganic & medicinal chemistry letters, 5(4), 1995, pp. 331-336
CHARACTERIZATION OF A CONTINUOUS FLUOROGENIC ASSAY FOR CALPAIN-I - KINETIC EVALUATION OF PEPTIDE ALDEHYDES, HALOMETHYL KETONES AND (ACYLOXY)METHYL KETONES AS INHIBITORS OF THE ENZYME
Authors: HARRIS AL GREGORY JS MAYCOCK AL GRAYBILL TL OSIFO IK SCHMIDT SJ DOLLE RE
Citation: Al. Harris et al., CHARACTERIZATION OF A CONTINUOUS FLUOROGENIC ASSAY FOR CALPAIN-I - KINETIC EVALUATION OF PEPTIDE ALDEHYDES, HALOMETHYL KETONES AND (ACYLOXY)METHYL KETONES AS INHIBITORS OF THE ENZYME, Bioorganic & medicinal chemistry letters, 5(4), 1995, pp. 393-398
BIOLOGICAL-ACTIVITY OF WIN-63759, AN ORALLY BIOAVAILABLE INHIBITOR OFHUMAN NEUTROPHIL ELASTASE
Authors: SILVER PJ GORDON RJ PAGANI ED JOHNSON JA MAYCOCK AL DUNLAP RP FERGUSON EW FRANKE CA DROZD ML ROBINSON DT EICKHOFF WM BAIZMAN ER SUBRAMANYAM C DESAI RC HLASTA DJ NEWTON JF
Citation: Pj. Silver et al., BIOLOGICAL-ACTIVITY OF WIN-63759, AN ORALLY BIOAVAILABLE INHIBITOR OFHUMAN NEUTROPHIL ELASTASE, Drug development research, 34(3), 1995, pp. 306-316
ORALLY BIOAVAILABLE BENZISOTHIAZOLONE INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE
Authors: HLASTA DJ SUBRAMANYAM C BELL MR CARABATEAS PM COURT JJ DESAI RC DROZD ML EICKHOFF WM FERGUSON EW GORDON RJ JOHNSON JA KUMAR V MAYCOCK AL MUELLER KR PAGANI ED ROBINSON DT SAINDANE MT SILVER PJ SUBRAMANIAN S DUNLAP RP FRANKE CA MURA AJ ROWLANDS AG
Citation: Dj. Hlasta et al., ORALLY BIOAVAILABLE BENZISOTHIAZOLONE INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE, Journal of medicinal chemistry, 38(5), 1995, pp. 739-744
ORALLY-ACTIVE BETA-LACTAM INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE .3. STEREOSPECIFIC SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS FOR 3,3-DIALKYLAZETIDIN-2-ONES
Authors: FINKE PE SHAH SK FLETCHER DS ASHE BM BRAUSE KA CHANDLER GO DELLEA PS HAND KM MAYCOCK AL OSINGA DG UNDERWOOD DJ WESTON H DAVIES P DOHERTY JB
Citation: Pe. Finke et al., ORALLY-ACTIVE BETA-LACTAM INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE .3. STEREOSPECIFIC SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS FOR 3,3-DIALKYLAZETIDIN-2-ONES, Journal of medicinal chemistry, 38(13), 1995, pp. 2449-2462
MECHANISM OF INHIBITION OF HUMAN-LEUKOCYTE ELASTASE BY BETA-LACTAMS .2. STABILITY, REACTIVATION KINETICS, AND PRODUCTS OF BETA-LACTAM-DERIVED E-I COMPLEXES
Authors: GREEN BG CHABIN R MILLS S UNDERWOOD DJ SHAH SK KUO D GALE P MAYCOCK AL LIESCH J BURGEY CS DOHERTY JB DORN CP FINKE PE HAGMANN WK HALE JJ MACCOSS M WESTLER WM KNIGHT WB
Citation: Bg. Green et al., MECHANISM OF INHIBITION OF HUMAN-LEUKOCYTE ELASTASE BY BETA-LACTAMS .2. STABILITY, REACTIVATION KINETICS, AND PRODUCTS OF BETA-LACTAM-DERIVED E-I COMPLEXES, Biochemistry, 34(44), 1995, pp. 14331-14343
INHIBITION OF HUMAN-LEUKOCYTE ELASTASE .5. INHIBITION BY 6-ALKYL SUBSTITUTED PENEM BENZYL-ESTERS
Authors: FINKE PE DAHLGREN ME WESTON H MAYCOCK AL DOHERTY JB
Citation: Pe. Finke et al., INHIBITION OF HUMAN-LEUKOCYTE ELASTASE .5. INHIBITION BY 6-ALKYL SUBSTITUTED PENEM BENZYL-ESTERS, Bioorganic & medicinal chemistry letters, 3(11), 1993, pp. 2277-2282
INHIBITION OF HUMAN-LEUKOCYTE ELASTASE .6. INHIBITION BY 6-SUBSTITUTED PENICILLIN ESTERS
Authors: THOMPSON KR FINKE PE SHAH SK ASHE BM DAHLGREN ME MAYCOCK AL DOHERTY JB
Citation: Kr. Thompson et al., INHIBITION OF HUMAN-LEUKOCYTE ELASTASE .6. INHIBITION BY 6-SUBSTITUTED PENICILLIN ESTERS, Bioorganic & medicinal chemistry letters, 3(11), 1993, pp. 2283-2288
INHIBITION OF HUMAN-LEUKOCYTE ELASTASE .7. INHIBITION BY 6-SUBSTITUTED PENICILLIN AMIDES
Authors: THOMPSON KR FINKE PE SHAH SK ASHE BM DAHLGREN ME DELLEA PS FLETCHER DS HAND KM MAYCOCK AL DOHERTY JB
Citation: Kr. Thompson et al., INHIBITION OF HUMAN-LEUKOCYTE ELASTASE .7. INHIBITION BY 6-SUBSTITUTED PENICILLIN AMIDES, Bioorganic & medicinal chemistry letters, 3(11), 1993, pp. 2289-2294
MONOCYCLIC BETA-LACTAM INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE - STEREOSPECIFIC SYNTHESIS AND ACTIVITY OF 3,4-DISUBSTITUTED-2-AZETIDINONES
Authors: SHAH SK FINKE PE BRAUSE KA CHANDLER GO ASHE BM WESTON H MAYCOCK AL MUMFORD RA DOHERTY JB
Citation: Sk. Shah et al., MONOCYCLIC BETA-LACTAM INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE - STEREOSPECIFIC SYNTHESIS AND ACTIVITY OF 3,4-DISUBSTITUTED-2-AZETIDINONES, Bioorganic & medicinal chemistry letters, 3(11), 1993, pp. 2295-2298
CHARACTERIZATION OF A CONTINUOUS ASSAY FOR CALPAIN
Authors: HARRIS AL GREGORY JS DOLLE RE MAYCOCK AL
Citation: Al. Harris et al., CHARACTERIZATION OF A CONTINUOUS ASSAY FOR CALPAIN, The FASEB journal, 7(7), 1993, pp. 1182-1182
CHEMICAL, BIOCHEMICAL, PHARMACOKINETIC, AND BIOLOGICAL PROPERTIES OF L-680,833 - A POTENT, ORALLY-ACTIVE MONOCYCLIC BETA-LACTAM INHIBITOR OF HUMAN POLYMORPHONUCLEAR LEUKOCYTE ELASTASE
Authors: DOHERTY JB SHAH SK FINKE PE DORN CP HAGMANN WK HALE JJ KISSINGER AL THOMPSON KR BRAUSE K CHANDLER GO KNIGHT WB MAYCOCK AL AHSE BM WESTON H GALE P MUMFORD RA ANDERSEN OF WILLIAMS HR NOLAN TE FRANKENFIELD DL UNDERWOOD D VYAS KP KARI PH DAHLGREN ME MAO J FLETCHER DS DELLEA PS HAND KM OSINGA DG PETERSON LB WILLIAMS DT METZGER JM BONNEY RJ HUMES JL PACHOLOK SP HANLON WA OPAS E STOLK J DAVIES P
Citation: Jb. Doherty et al., CHEMICAL, BIOCHEMICAL, PHARMACOKINETIC, AND BIOLOGICAL PROPERTIES OF L-680,833 - A POTENT, ORALLY-ACTIVE MONOCYCLIC BETA-LACTAM INHIBITOR OF HUMAN POLYMORPHONUCLEAR LEUKOCYTE ELASTASE, Proceedings of the National Academy of Sciences of the United Statesof America, 90(18), 1993, pp. 8727-8731
MECHANISM OF INHIBITION OF HUMAN-LEUKOCYTE ELASTASE BY MONOCYCLIC BETA-LACTAMS
Authors: CHABIN R GREEN BG GALE P MAYCOCK AL WESTON H DORN CP FINKE PE HAGMANN WK HALE JJ MACCOSS M SHAH SK UNDERWOOD D DOHERTY JB KNIGHT WB
Citation: R. Chabin et al., MECHANISM OF INHIBITION OF HUMAN-LEUKOCYTE ELASTASE BY MONOCYCLIC BETA-LACTAMS, Biochemistry, 32(34), 1993, pp. 8970-8980
Risultati: 1-13 |