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Results: 1-25 | 26-27
Results: 1-25/27
PREDICTION OF ANTISENSE OLIGONUCLEOTIDE EFFICACY BY IN-VITRO METHODS
Authors: MATVEEVA O FELDEN B TSODIKOV A JOHNSTON J MONIA BP ATKINS JF GESTELAND RF FREIER SM
Citation: O. Matveeva et al., PREDICTION OF ANTISENSE OLIGONUCLEOTIDE EFFICACY BY IN-VITRO METHODS, Nature biotechnology, 16(13), 1998, pp. 1374-1375
BIOPHYSICAL AND ANTISENSE PROPERTIES OF OLIGODEOXYNUCLEOTIDES CONTAINING 7-PROPYNYL-7-DEAZA-2-AMINO-2'-DEOXYADENOSINES, 7-IODO-7-DEAZA-2-AMINO-2'-DEOXYADENOSINES AND 7-CYANO-7-DEAZA-2-AMINO-2'-DEOXYADENOSINES
Authors: BALOW G MOHAN V LESNIK EA JOHNSTON JF MONIA BP ACEVEDO OL
Citation: G. Balow et al., BIOPHYSICAL AND ANTISENSE PROPERTIES OF OLIGODEOXYNUCLEOTIDES CONTAINING 7-PROPYNYL-7-DEAZA-2-AMINO-2'-DEOXYADENOSINES, 7-IODO-7-DEAZA-2-AMINO-2'-DEOXYADENOSINES AND 7-CYANO-7-DEAZA-2-AMINO-2'-DEOXYADENOSINES, Nucleic acids research, 26(14), 1998, pp. 3350-3357
EXPOSURE OF HUMAN VASCULAR SMOOTH-MUSCLE CELLS TO RAF-1 ANTISENSE OLIGODEOXYNUCLEOTIDES - CELLULAR-RESPONSES AND PHARMACODYNAMIC IMPLICATIONS
Authors: SCHUMACHER C CIOFFI CL SHARIF H HASTON W MONIA BP WENNOGLE L
Citation: C. Schumacher et al., EXPOSURE OF HUMAN VASCULAR SMOOTH-MUSCLE CELLS TO RAF-1 ANTISENSE OLIGODEOXYNUCLEOTIDES - CELLULAR-RESPONSES AND PHARMACODYNAMIC IMPLICATIONS, Molecular pharmacology, 53(1), 1998, pp. 97-104
CHARACTERIZATION AND MODULATION OF IMMUNE STIMULATION BY MODIFIED OLIGONUCLEOTIDES
Authors: BOGGS RT MCGRAW K CONDON T FLOURNOY S VILLIET P BENNETT CF MONIA BP
Citation: Rt. Boggs et al., CHARACTERIZATION AND MODULATION OF IMMUNE STIMULATION BY MODIFIED OLIGONUCLEOTIDES, ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT, 7(5), 1997, pp. 461-471
ANTITUMOR-ACTIVITY OF A C-RAF ANTISENSE OLIGONUCLEOTIDE IN COMBINATION WITH STANDARD CHEMOTHERAPEUTIC-AGENTS AGAINST VARIOUS HUMAN TUMORS TRANSPLANTED SUBCUTANEOUSLY INTO NUDE-MICE
Authors: GEIGER T MULLER M MONIA BP FABBRO D
Citation: T. Geiger et al., ANTITUMOR-ACTIVITY OF A C-RAF ANTISENSE OLIGONUCLEOTIDE IN COMBINATION WITH STANDARD CHEMOTHERAPEUTIC-AGENTS AGAINST VARIOUS HUMAN TUMORS TRANSPLANTED SUBCUTANEOUSLY INTO NUDE-MICE, Clinical cancer research, 3(7), 1997, pp. 1179-1185
2ND-GENERATION ANTISENSE OLIGONUCLEOTIDES-INHIBITION OF PKC-ALPHA ANDC-RAF KINASE EXPRESSION BY CHIMERIC OLIGONUCLEOTIDES INCORPORATING 6'-SUBSTITUTED CARBOCYCLIC NUCLEOSIDES AND 2'-O-ETHYLENE GLYCOL SUBSTITUTED RIBONUCLEOSIDES
Authors: ALTMANN KH MARTIN P DEAN NM MONIA BP
Citation: Kh. Altmann et al., 2ND-GENERATION ANTISENSE OLIGONUCLEOTIDES-INHIBITION OF PKC-ALPHA ANDC-RAF KINASE EXPRESSION BY CHIMERIC OLIGONUCLEOTIDES INCORPORATING 6'-SUBSTITUTED CARBOCYCLIC NUCLEOSIDES AND 2'-O-ETHYLENE GLYCOL SUBSTITUTED RIBONUCLEOSIDES, Nucleosides & nucleotides, 16(7-9), 1997, pp. 917-926
CHOLESTEROL CONJUGATED UNIFORM AND GAPMER PHOSPHOROTHIOATE OLIGONUCLEOTIDES TARGETED AGAINST PKC-ALPHA AND C-RAF GENE-EXPRESSION
Authors: MANOHARAN M TIVEL KL INAMATI G MONIA BP DEAN N COOK PD
Citation: M. Manoharan et al., CHOLESTEROL CONJUGATED UNIFORM AND GAPMER PHOSPHOROTHIOATE OLIGONUCLEOTIDES TARGETED AGAINST PKC-ALPHA AND C-RAF GENE-EXPRESSION, Nucleosides & nucleotides, 16(7-9), 1997, pp. 1139-1140
PRECLINICAL PROFILING OF MODIFIED OLIGONUCLEOTIDES - ANTICOAGULATION AND PHARMACOKINETIC PROPERTIES
Authors: NICKLIN PL AMBLER J MITCHELSON A BAYLEY D PHILLIPS JA CRAIG SJ MONIA BP
Citation: Pl. Nicklin et al., PRECLINICAL PROFILING OF MODIFIED OLIGONUCLEOTIDES - ANTICOAGULATION AND PHARMACOKINETIC PROPERTIES, Nucleosides & nucleotides, 16(7-9), 1997, pp. 1145-1153
FIRST-GENERATION AND 2ND-GENERATION ANTISENSE INHIBITORS TARGETED TO HUMAN C-RAF KINASE - IN-VITRO AND IN-VIVO STUDIES
Authors: MONIA BP
Citation: Bp. Monia, FIRST-GENERATION AND 2ND-GENERATION ANTISENSE INHIBITORS TARGETED TO HUMAN C-RAF KINASE - IN-VITRO AND IN-VIVO STUDIES, Anti-cancer drug design, 12(5), 1997, pp. 327-339
SELECTIVE-INHIBITION OF A-RAF AND C-RAF MESSENGER-RNA EXPRESSION BY ANTISENSE OLIGODEOXYNUCLEOTIDES IN RAT VASCULAR SMOOTH-MUSCLE CELLS - ROLE OF A-RAF AND C-RAF IN SERUM-INDUCED PROLIFERATION
Authors: CIOFFI CL GARAY M JOHNSTON JF MCGRAW K BOGGS RT HRENIUK D MONIA BP
Citation: Cl. Cioffi et al., SELECTIVE-INHIBITION OF A-RAF AND C-RAF MESSENGER-RNA EXPRESSION BY ANTISENSE OLIGODEOXYNUCLEOTIDES IN RAT VASCULAR SMOOTH-MUSCLE CELLS - ROLE OF A-RAF AND C-RAF IN SERUM-INDUCED PROLIFERATION, Molecular pharmacology, 51(3), 1997, pp. 383-389
PKC-EPSILON IS REQUIRED FOR MECANOSENSITIVE ACTIVATION OF ERK1 2 IN ENDOTHELIAL-CELLS/
Authors: TRAUB O MONIA BP DEAN NM BERK BC
Citation: O. Traub et al., PKC-EPSILON IS REQUIRED FOR MECANOSENSITIVE ACTIVATION OF ERK1 2 IN ENDOTHELIAL-CELLS/, The Journal of biological chemistry, 272(50), 1997, pp. 31251-31257
ANTITUMOR-ACTIVITY OF A PHOSPHOROTHIOATE ANTISENSE OLIGODEOXYNUCLEOTIDE TARGETED AGAINST C-RAF KINASE
Authors: MONIA BP JOHNSTON JF GEIGER T MULLER M FABBRO D
Citation: Bp. Monia et al., ANTITUMOR-ACTIVITY OF A PHOSPHOROTHIOATE ANTISENSE OLIGODEOXYNUCLEOTIDE TARGETED AGAINST C-RAF KINASE, Nature medicine, 2(6), 1996, pp. 668-675
C-RAF-1 KINASE ANTISENSE OLIGONUCLEOTIDE BLOCKS RAF-1 MESSENGER-RNA EXPRESSION AND ALLOGRAFT-REJECTION
Authors: STEPKOWSKI SM WANG ME MONIA BP
Citation: Sm. Stepkowski et al., C-RAF-1 KINASE ANTISENSE OLIGONUCLEOTIDE BLOCKS RAF-1 MESSENGER-RNA EXPRESSION AND ALLOGRAFT-REJECTION, The FASEB journal, 10(6), 1996, pp. 1143-1143
PHOSPHOROTHIOATE ANTISENSE OLIGODEOXYNUCLEOTIDE INHIBITORS TARGETED SPECIFICALLY TO HUMAN C-RAF-1 OR HA-RAS DISPLAY POTENT ANTITUMOR-ACTIVITY
Authors: MONIA BP JOHNSTON JF GEIGER T MULLER M ALTMANN KH NICKLIN P PHILLIPS J FABBRO D
Citation: Bp. Monia et al., PHOSPHOROTHIOATE ANTISENSE OLIGODEOXYNUCLEOTIDE INHIBITORS TARGETED SPECIFICALLY TO HUMAN C-RAF-1 OR HA-RAS DISPLAY POTENT ANTITUMOR-ACTIVITY, The FASEB journal, 10(3), 1996, pp. 1058-1058
2ND-GENERATION ANTISENSE OLIGONUCLEOTIDES - STRUCTURE-ACTIVITY-RELATIONSHIPS AND THE DESIGN OF IMPROVED SIGNAL-TRANSDUCTION INHIBITORS
Authors: ALTMANN KH FABBRO D DEAN NM GEIGER T MONIA BP MULLER M NICKLIN P
Citation: Kh. Altmann et al., 2ND-GENERATION ANTISENSE OLIGONUCLEOTIDES - STRUCTURE-ACTIVITY-RELATIONSHIPS AND THE DESIGN OF IMPROVED SIGNAL-TRANSDUCTION INHIBITORS, Biochemical Society transactions, 24(3), 1996, pp. 630-637
DESTABILIZATION OF RAF-1 BY GELDANAMYCIN LEADS TO DISRUPTION OF THE RAF-1-MEK-MITOGEN-ACTIVATED PROTEIN-KINASE SIGNALING PATHWAY
Authors: SCHULTE TW BLAGOSKLONNY MV ROMANOVA L MUSHINSKI JF MONIA BP JOHNSTON JF NGUYEN P TREPEL J NECKERS LM
Citation: Tw. Schulte et al., DESTABILIZATION OF RAF-1 BY GELDANAMYCIN LEADS TO DISRUPTION OF THE RAF-1-MEK-MITOGEN-ACTIVATED PROTEIN-KINASE SIGNALING PATHWAY, Molecular and cellular biology, 16(10), 1996, pp. 5839-5845
SEQUENCE-SPECIFIC ANTITUMOR-ACTIVITY OF A PHOSPHOROTHIOATE OLIGODEOXYRIBONUCLEOTIDE TARGETED TO HUMAN C-RAF KINASE SUPPORTS AN ANTISENSE MECHANISM OF ACTION IN-VIVO
Authors: MONIA BP SASMOR H JOHNSTON JF FREIER SM LESNIK EA MULLER M GEIGER T ALTMANN KH MOSER H FABBRO D
Citation: Bp. Monia et al., SEQUENCE-SPECIFIC ANTITUMOR-ACTIVITY OF A PHOSPHOROTHIOATE OLIGODEOXYRIBONUCLEOTIDE TARGETED TO HUMAN C-RAF KINASE SUPPORTS AN ANTISENSE MECHANISM OF ACTION IN-VIVO, Proceedings of the National Academy of Sciences of the United Statesof America, 93(26), 1996, pp. 15481-15484
2'-O-AMINOPROPYL RIBONUCLEOTIDES - A ZWITTERIONIC MODIFICATION THAT ENHANCES THE EXONUCLEASE RESISTANCE AND BIOLOGICAL-ACTIVITY OF ANTISENSE OLIGONUCLEOTIDES
Authors: GRIFFEY RH MONIA BP CUMMINS LL FREIER S GREIG MJ GUINOSSO CJ LESNIK E MANALILI SM MOHAN V OWENS S ROSS BR SASMOR H WANCEWICZ E WEILER K WHEELER PD COOK PD
Citation: Rh. Griffey et al., 2'-O-AMINOPROPYL RIBONUCLEOTIDES - A ZWITTERIONIC MODIFICATION THAT ENHANCES THE EXONUCLEASE RESISTANCE AND BIOLOGICAL-ACTIVITY OF ANTISENSE OLIGONUCLEOTIDES, Journal of medicinal chemistry, 39(26), 1996, pp. 5100-5109
ANTISENSE OLIGONUCLEOTIDES DEMONSTRATE A DOMINANT ROLE OF C-KI-RAS PROTEINS IN REGULATING THE PROLIFERATION OF DIPLOID HUMAN FIBROBLASTS
Authors: CHEN G OH S MONIA BP STACEY DW
Citation: G. Chen et al., ANTISENSE OLIGONUCLEOTIDES DEMONSTRATE A DOMINANT ROLE OF C-KI-RAS PROTEINS IN REGULATING THE PROLIFERATION OF DIPLOID HUMAN FIBROBLASTS, The Journal of biological chemistry, 271(45), 1996, pp. 28259-28265
2ND GENERATION OF ANTISENSE OLIGONUCLEOTIDES - FROM NUCLEASE RESISTANCE TO BIOLOGICAL EFFICACY IN ANIMALS
Authors: ALTMANN KH DEAN NM FABBRO D FREIER SM GEIGER T HANER R HUSKEN D MARTIN P MONIA BP MULLER M NATT F NICKLIN P PHILLIPS J PIELES U SASMOR H MOSER HE
Citation: Kh. Altmann et al., 2ND GENERATION OF ANTISENSE OLIGONUCLEOTIDES - FROM NUCLEASE RESISTANCE TO BIOLOGICAL EFFICACY IN ANIMALS, Chimia, 50(4), 1996, pp. 168-176
MODIFIED OLIGONUCLEOTIDES - HYBRIDIZATION PROPERTIES, PHARMACOKINETICPROPERTIES AND PHARMACOLOGICAL ACTIVITY
Authors: FREIER SM BENNETT CF COOK PD CROOKE ST CUMMINS LL DEAN NM ECKER DJ GRIFFEY RH GUINOSSO CJ KORNBRUST D LEEDS J LESNIK EA MONIA BP SANGHVI YS ZUCKERMAN JE
Citation: Sm. Freier et al., MODIFIED OLIGONUCLEOTIDES - HYBRIDIZATION PROPERTIES, PHARMACOKINETICPROPERTIES AND PHARMACOLOGICAL ACTIVITY, Journal of cellular biochemistry, 1995, pp. 205-205
KINETIC CHARACTERISTICS OF ESCHERICHIA-COLI RNASE H1 - CLEAVAGE OF VARIOUS ANTISENSE OLIGONUCLEOTIDE-RNA DUPLEXES
Authors: CROOKE ST LEMONIDIS KM NEILSON L GRIFFEY R LESNIK EA MONIA BP
Citation: St. Crooke et al., KINETIC CHARACTERISTICS OF ESCHERICHIA-COLI RNASE H1 - CLEAVAGE OF VARIOUS ANTISENSE OLIGONUCLEOTIDE-RNA DUPLEXES, Biochemical journal, 312, 1995, pp. 599-608
MITOGEN-ACTIVATED PROTEIN (MAP) KINASE IS REGULATED BY THE MAP KINASEPHOSPHATASE (MKP-1) IN VASCULAR SMOOTH-MUSCLE CELLS
Authors: DUFF JL MONIA BP BERK BC
Citation: Jl. Duff et al., MITOGEN-ACTIVATED PROTEIN (MAP) KINASE IS REGULATED BY THE MAP KINASEPHOSPHATASE (MKP-1) IN VASCULAR SMOOTH-MUSCLE CELLS, The Journal of biological chemistry, 270(13), 1995, pp. 7161-7166
INHIBITION OF PROTEOLYSIS AND CELL-CYCLE PROGRESSION IN A MULTIUBIQUITINATION-DEFICIENT YEAST MUTANT
Authors: FINLEY D SADIS S MONIA BP BOUCHER P ECKER DJ CROOKE ST CHAU V
Citation: D. Finley et al., INHIBITION OF PROTEOLYSIS AND CELL-CYCLE PROGRESSION IN A MULTIUBIQUITINATION-DEFICIENT YEAST MUTANT, Molecular and cellular biology, 14(8), 1994, pp. 5501-5509
REMARKABLE ENHANCEMENT OF BINDING-AFFINITY OF HETEROCYCLE-MODIFIED DNA TO DNA AND RNA - SYNTHESIS, CHARACTERIZATION AND BIOPHYSICAL EVALUATION OF N-2-IMIDAZOLYLPROPYLGUANINE AND N-2-IMIDAZOLYLPROPYL-2-AMINOADENINE MODIFIED OLIGONUCLEOTIDES
Authors: RAMASAMY KS ZOUNES M GONZALEZ C FREIER SM LESNIK EA CUMMINS LL GRIFFEY RH MONIA BP COOK PD
Citation: Ks. Ramasamy et al., REMARKABLE ENHANCEMENT OF BINDING-AFFINITY OF HETEROCYCLE-MODIFIED DNA TO DNA AND RNA - SYNTHESIS, CHARACTERIZATION AND BIOPHYSICAL EVALUATION OF N-2-IMIDAZOLYLPROPYLGUANINE AND N-2-IMIDAZOLYLPROPYL-2-AMINOADENINE MODIFIED OLIGONUCLEOTIDES, Tetrahedron letters, 35(2), 1994, pp. 215-218
Risultati: 1-25 | 26-27