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Results: 1-21 |
Results: 21
The synthesis of amino-acid functionalized beta-carbolines as topoisomerase II inhibitors
Authors: Deveau, AM Labroli, MA Dieckhaus, CM Barthen, MT Smith, KS Macdonald, TL
Citation: Am. Deveau et al., The synthesis of amino-acid functionalized beta-carbolines as topoisomerase II inhibitors, BIOORG MED, 11(10), 2001, pp. 1251-1255
The chemistry, toxicology, and identification in rat and human urine of 4-hydroxy-5-phenyl-1,3-oxazaperhydroin-2-one: A reactive metabolite in felbamate bioactivation
Authors: Dieckhaus, CM Santos, WL Sofia, RD Macdonald, TL
Citation: Cm. Dieckhaus et al., The chemistry, toxicology, and identification in rat and human urine of 4-hydroxy-5-phenyl-1,3-oxazaperhydroin-2-one: A reactive metabolite in felbamate bioactivation, CHEM RES T, 14(8), 2001, pp. 958-964
Role of glutathione S-transferases A1-1, M1-1, and P1-1 in the detoxification of 2-phenylpropenal, a reactive felbamate metabolite
Authors: Dieckhaus, CM Roller, SG Santos, WL Sofia, RD Macdonald, TL
Citation: Cm. Dieckhaus et al., Role of glutathione S-transferases A1-1, M1-1, and P1-1 in the detoxification of 2-phenylpropenal, a reactive felbamate metabolite, CHEM RES T, 14(5), 2001, pp. 511-516
Selective A(2A) adenosine receptor activation reduces skin pressure ulcer formation and inflammation
Authors: Peirce, SM Skalak, TC Rieger, JM Macdonald, TL Linden, J
Citation: Sm. Peirce et al., Selective A(2A) adenosine receptor activation reduces skin pressure ulcer formation and inflammation, AM J P-HEAR, 281(1), 2001, pp. H67-H74
Design, synthesis, and evaluation of novel A(2A) adenosine receptor agonists
Authors: Rieger, JM Brown, ML Sullivan, GW Linden, J Macdonald, TL
Citation: Jm. Rieger et al., Design, synthesis, and evaluation of novel A(2A) adenosine receptor agonists, J MED CHEM, 44(4), 2001, pp. 531-539
Lysophosphatidic acid-induced mitogenesis is regulated by lipid phosphate phosphatases and is Edg-receptor independent
Authors: Hooks, SB Santos, WL Im, DS Heise, CE Macdonald, TL Lynch, KR
Citation: Sb. Hooks et al., Lysophosphatidic acid-induced mitogenesis is regulated by lipid phosphate phosphatases and is Edg-receptor independent, J BIOL CHEM, 276(7), 2001, pp. 4611-4621
Accelerated S-nitrosothiol breakdown by amyotrophic lateral sclerosis mutant copper,zinc-superoxide dismutase
Authors: Johnson, MA Macdonald, TL Mannick, JB Conaway, MR Gaston, B
Citation: Ma. Johnson et al., Accelerated S-nitrosothiol breakdown by amyotrophic lateral sclerosis mutant copper,zinc-superoxide dismutase, J BIOL CHEM, 276(43), 2001, pp. 39872-39878
Molecular pharmacology of T-type Ca2+ channels
Authors: Heady, TN Gomora, JC Macdonald, TL Perez-Reyes, E
Citation: Tn. Heady et al., Molecular pharmacology of T-type Ca2+ channels, JPN J PHARM, 85(4), 2001, pp. 339-350
Pharmacological stress myocardial perfusion imaging with the potent and selective A(2A) adenosine receptor agonists ATL193 and ATL146e administered by either intravenous infusion or bolus injection
Authors: Glover, DK Ruiz, M Takehana, K Petruzella, FD Riou, LM Rieger, JM Macdonald, TL Watson, DD Linden, J Beller, GA
Citation: Dk. Glover et al., Pharmacological stress myocardial perfusion imaging with the potent and selective A(2A) adenosine receptor agonists ATL193 and ATL146e administered by either intravenous infusion or bolus injection, CIRCULATION, 104(10), 2001, pp. 1181-1187
Cyclic AMP-dependent inhibition of human neutrophil oxidative activity by substituted 2-propynylcyclohexyl adenosine A(2A) receptor agonists
Authors: Sullivan, GW Rieger, JM Scheld, WM Macdonald, TL Linden, J
Citation: Gw. Sullivan et al., Cyclic AMP-dependent inhibition of human neutrophil oxidative activity by substituted 2-propynylcyclohexyl adenosine A(2A) receptor agonists, BR J PHARM, 132(5), 2001, pp. 1017-1026
Characterization of the human and mouse sphingosine 1-phosphate receptor, S1P(5) (Edg-8): Structure-activity relationship of sphingosine1-phosphate receptors
Authors: Im, DS Clemens, J Macdonald, TL Lynch, KR
Citation: Ds. Im et al., Characterization of the human and mouse sphingosine 1-phosphate receptor, S1P(5) (Edg-8): Structure-activity relationship of sphingosine1-phosphate receptors, BIOCHEM, 40(46), 2001, pp. 14053-14060
A facile, one-pot procedure for the preparation of 2-phenyl-1,3-propanediol monocarbamate, a metabolite of felbamate
Authors: Miller, TA Dieckhaus, CM Macdonald, TL
Citation: Ta. Miller et al., A facile, one-pot procedure for the preparation of 2-phenyl-1,3-propanediol monocarbamate, a metabolite of felbamate, ORG PROC R, 4(6), 2000, pp. 611-612
Comparative molecular field analysis of colchicine inhibition and tubulin polymerization for combretastatins binding to the colchicine binding site on beta-tubulin
Authors: Brown, ML Rieger, JM Macdonald, TL
Citation: Ml. Brown et al., Comparative molecular field analysis of colchicine inhibition and tubulin polymerization for combretastatins binding to the colchicine binding site on beta-tubulin, BIO MED CH, 8(6), 2000, pp. 1433-1441
5-HETE congeners as modulators of cell proliferation
Authors: Miller, TA Ghosh, J Myers, CE Macdonald, TL
Citation: Ta. Miller et al., 5-HETE congeners as modulators of cell proliferation, BIOORG MED, 10(17), 2000, pp. 1913-1916
A(2A) adenosine receptor-mediated inhibition of renal injury and neutrophil adhesion
Authors: Okusa, MD Linden, J Huang, LP Rieger, JM Macdonald, TL Huynh, LP
Citation: Md. Okusa et al., A(2A) adenosine receptor-mediated inhibition of renal injury and neutrophil adhesion, AM J P-REN, 279(5), 2000, pp. F809-F818
A mechanistic approach to understanding species differences in felbamate bioactivation: Relevance to drug-induced idiosyncratic reactions
Authors: Dieckhaus, CM Miller, TA Sofia, RD Macdonald, TL
Citation: Cm. Dieckhaus et al., A mechanistic approach to understanding species differences in felbamate bioactivation: Relevance to drug-induced idiosyncratic reactions, DRUG META D, 28(7), 2000, pp. 814-822
The synthesis, in vitro reactivity, and evidence for formation in humans of 5-phenyl-1,3-oxazinane-2,4-dione, a metabolite of felbamate
Authors: Thompson, CD Miller, TA Barthen, MT Dieckhaus, CM Sofia, RD Macdonald, TL
Citation: Cd. Thompson et al., The synthesis, in vitro reactivity, and evidence for formation in humans of 5-phenyl-1,3-oxazinane-2,4-dione, a metabolite of felbamate, DRUG META D, 28(4), 2000, pp. 434-439
Inhibition of human prostate cancer proliferation in vitro and in a mouse model by a compound synthesized to block Ca2+ entry
Authors: Haverstick, DM Heady, TN Macdonald, TL Lloyd, LS
Citation: Dm. Haverstick et al., Inhibition of human prostate cancer proliferation in vitro and in a mouse model by a compound synthesized to block Ca2+ entry, CANCER RES, 60(4), 2000, pp. 1002-1008
The synthesis and evaluation of temperature sensitive tubulin toxins
Authors: Miller, TA Bulman, AL Thompson, CD Macdonald, TL
Citation: Ta. Miller et al., The synthesis and evaluation of temperature sensitive tubulin toxins, BIOORG MED, 9(3), 1999, pp. 407-412
Structure-activity relationships of lysophosphatidic acid: Conformationally restricted backbone mimetics
Authors: Hopper, DW Ragan, SP Hooks, SB Lynch, KR Macdonald, TL
Citation: Dw. Hopper et al., Structure-activity relationships of lysophosphatidic acid: Conformationally restricted backbone mimetics, J MED CHEM, 42(6), 1999, pp. 963-970
Quantification in patient urine samples of felbamate and three metabolites: Acid carbamate and two mercapturic acids
Authors: Thompson, CD Barthen, MT Hopper, DW Miller, TA Quigg, M Hudspeth, C Montouris, G Marsh, L Perhach, JL Sofia, RD Macdonald, TL
Citation: Cd. Thompson et al., Quantification in patient urine samples of felbamate and three metabolites: Acid carbamate and two mercapturic acids, EPILEPSIA, 40(6), 1999, pp. 769-776
Risultati: 1-21 |