Authors:
Marriott, JH
Aherne, GW
Hardcastle, A
Jarman, M
Citation: Jh. Marriott et al., Synthesis of certain 2 '-deoxyuridine derivatives containing substituted phenoxy groups attached to C-5 '; Evaluation as potential dUTP analogues, NUCLEOS NUC, 20(9), 2001, pp. 1691-1704
Authors:
Bavetsias, V
Marriott, JH
Theti, DS
Melin, JC
Wilson, SC
Jackman, AL
Citation: V. Bavetsias et al., Cyclopenta[g]quinazoline-based antifolates: The effect of the chirality atthe 6-position on the inhibition of thymidylate synthase (TS), BIOORG MED, 11(23), 2001, pp. 3015-3017
Authors:
Marriott, JH
Barber, AMM
Hardcastle, IR
Rowlands, MG
Grimshaw, RM
Neidle, S
Jarman, M
Citation: Jh. Marriott et al., Synthesis of the farnesyl ether 2,3,5-trifluoro-6-hydroxy-4-[(E,E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yloxy]nitrobenzene, and related compounds containing a substituted hydroxytrifluorophenyl residue: novel inhibitors of protein farnesyltransferase, geranylgeranyltransferase I and squalene synthase, J CHEM S P1, (24), 2000, pp. 4265-4278
Authors:
Bavetsias, V
Marriott, JH
Melin, C
Kimbell, R
Matusiak, ZS
Boyle, FT
Jackman, AL
Citation: V. Bavetsias et al., Design and synthesis of cyclopenta[g]quinazoline-based antifolates as inhibitors of thymidylate synthase and potential antitumor agents, J MED CHEM, 43(10), 2000, pp. 1910-1926
Authors:
Marriott, JH
Neidle, S
Matusiak, Z
Bavetsias, V
Jackman, AL
Melin, C
Boyle, FT
Citation: Jh. Marriott et al., Chemoenzymatic preparation of the novel antifolate thymidylate synthase inhibitor N-(4-{N-[(6S)-2-methyl-4-oxo-3,4,7,8-tetrahydro-6H-cyclopenta [g]quinazolin-6-yl]-N-(prop-2-ynyl)amino}-benzoyl)-L-glutamic acid and its glutamyl cleavage product, J CHEM S P1, (11), 1999, pp. 1495-1503