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Results: 1-7 |
Results: 7
Synthesis of certain 2 '-deoxyuridine derivatives containing substituted phenoxy groups attached to C-5 '; Evaluation as potential dUTP analogues
Authors: Marriott, JH Aherne, GW Hardcastle, A Jarman, M
Citation: Jh. Marriott et al., Synthesis of certain 2 '-deoxyuridine derivatives containing substituted phenoxy groups attached to C-5 '; Evaluation as potential dUTP analogues, NUCLEOS NUC, 20(9), 2001, pp. 1691-1704
Cyclopenta[g]quinazoline-based antifolates: The effect of the chirality atthe 6-position on the inhibition of thymidylate synthase (TS)
Authors: Bavetsias, V Marriott, JH Theti, DS Melin, JC Wilson, SC Jackman, AL
Citation: V. Bavetsias et al., Cyclopenta[g]quinazoline-based antifolates: The effect of the chirality atthe 6-position on the inhibition of thymidylate synthase (TS), BIOORG MED, 11(23), 2001, pp. 3015-3017
Polymer-assisted solution-phase library synthesis of 4-alkoxy-2-hydroxy-3,5,6-trifluorobenzoic acids
Authors: Hardcastle, IR Barber, AM Marriott, JH Jarman, M
Citation: Ir. Hardcastle et al., Polymer-assisted solution-phase library synthesis of 4-alkoxy-2-hydroxy-3,5,6-trifluorobenzoic acids, TETRAHEDR L, 42(7), 2001, pp. 1363-1365
Synthesis of the farnesyl ether 2,3,5-trifluoro-6-hydroxy-4-[(E,E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yloxy]nitrobenzene, and related compounds containing a substituted hydroxytrifluorophenyl residue: novel inhibitors of protein farnesyltransferase, geranylgeranyltransferase I and squalene synthase
Authors: Marriott, JH Barber, AMM Hardcastle, IR Rowlands, MG Grimshaw, RM Neidle, S Jarman, M
Citation: Jh. Marriott et al., Synthesis of the farnesyl ether 2,3,5-trifluoro-6-hydroxy-4-[(E,E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yloxy]nitrobenzene, and related compounds containing a substituted hydroxytrifluorophenyl residue: novel inhibitors of protein farnesyltransferase, geranylgeranyltransferase I and squalene synthase, J CHEM S P1, (24), 2000, pp. 4265-4278
Design and synthesis of cyclopenta[g]quinazoline-based antifolates as inhibitors of thymidylate synthase and potential antitumor agents
Authors: Bavetsias, V Marriott, JH Melin, C Kimbell, R Matusiak, ZS Boyle, FT Jackman, AL
Citation: V. Bavetsias et al., Design and synthesis of cyclopenta[g]quinazoline-based antifolates as inhibitors of thymidylate synthase and potential antitumor agents, J MED CHEM, 43(10), 2000, pp. 1910-1926
Solid-phase synthesis of novel inhibitors of farnesyl transferase
Authors: Barber, AM Hardcastle, IR Rowlands, MG Nutley, BP Marriott, JH Jarman, M
Citation: Am. Barber et al., Solid-phase synthesis of novel inhibitors of farnesyl transferase, BIOORG MED, 9(4), 1999, pp. 623-626
Chemoenzymatic preparation of the novel antifolate thymidylate synthase inhibitor N-(4-{N-[(6S)-2-methyl-4-oxo-3,4,7,8-tetrahydro-6H-cyclopenta [g]quinazolin-6-yl]-N-(prop-2-ynyl)amino}-benzoyl)-L-glutamic acid and its glutamyl cleavage product
Authors: Marriott, JH Neidle, S Matusiak, Z Bavetsias, V Jackman, AL Melin, C Boyle, FT
Citation: Jh. Marriott et al., Chemoenzymatic preparation of the novel antifolate thymidylate synthase inhibitor N-(4-{N-[(6S)-2-methyl-4-oxo-3,4,7,8-tetrahydro-6H-cyclopenta [g]quinazolin-6-yl]-N-(prop-2-ynyl)amino}-benzoyl)-L-glutamic acid and its glutamyl cleavage product, J CHEM S P1, (11), 1999, pp. 1495-1503
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