Authors:
McGuigan, C
Barucki, H
Carangio, A
Blewett, S
Srinivasan, S
Andrei, G
Snoeck, R
De Clercq, E
Balzarini, J
Citation: C. Mcguigan et al., Novel aryl substituted bicyclic furo nucleosides as extremely potent and selective anti-VZV agents, NUCLEOS NUC, 20(4-7), 2001, pp. 287-296
Authors:
Carangio, A
McGuigan, C
Cahard, D
Andrei, G
Snoeck, R
De Clercq, E
Balzarini, J
Citation: A. Carangio et al., Synthesis and in vitro evaluation of novel anti-varicella-zoster virus (VZV) nucleosides, NUCLEOS NUC, 20(4-7), 2001, pp. 653-656
Authors:
Srinivasan, S
McGuigan, C
Andrei, G
Snoeck, R
De Clercq, E
Balzarini, J
Citation: S. Srinivasan et al., Bicyclic nucleoside inhibitors of varicella-zoster virus (VZV): Effect of terminal unsaturation in the side-chain, NUCLEOS NUC, 20(4-7), 2001, pp. 763-766
Authors:
Blewett, S
McGuigan, C
Barucki, H
Andrei, G
Snoeck, R
De Clercq, E
Balzarini, J
Citation: S. Blewett et al., Bicyclic furo pyrimidine nucleosides with aryloxyphenyl and halophenyl substituted side chains as potent and selective Varicella-Zoster Virus inhibitors, NUCLEOS NUC, 20(4-7), 2001, pp. 1063-1066
Authors:
Srinivasan, S
McGuigan, C
Andrei, G
Snoeck, R
De Clercq, E
Balzarini, J
Citation: S. Srinivasan et al., Bicyclic nucleoside inhibitors of Varicella-Zoster virus (VZV): The effectof terminal unsaturation in the side chain, BIOORG MED, 11(3), 2001, pp. 391-393
Authors:
Allender, CJ
Brain, KR
Ballatore, C
Cahard, D
Siddiqui, A
McGuigan, C
Citation: Cj. Allender et al., Separation of individual antiviral nucleotide prodrugs from synthetic mixtures using cross-reactivity of a molecularly imprinted stationary phase, ANALYT CHIM, 435(1), 2001, pp. 107-113
Authors:
McGuigan, C
Slater, MJ
Parry, NR
Perry, A
Harris, S
Citation: C. Mcguigan et al., Synthesis and antiviral activity of acyclovir-5 '-(phenyl methoxy alaninyl) phosphate as a possible membrane-soluble nucleotide prodrug, BIOORG MED, 10(7), 2000, pp. 645-647
Authors:
Knaggs, MH
McGuigan, C
Harris, SA
Heshmati, P
Cahard, D
Gilbert, IH
Balzarini, J
Citation: Mh. Knaggs et al., A QSAR study investigating the effect of L-alanine ester variation on the anti-HIV activity of some phosphoramidate derivatives of d4T, BIOORG MED, 10(18), 2000, pp. 2075-2078
Authors:
Brancale, A
McGuigan, C
Andrei, G
Snoeck, R
De Clercq, E
Balzarini, J
Citation: A. Brancale et al., Bicyclic nucleoside inhibitors of varicella-zoster virus (VZV): The effectof a terminal halogen substitution in the side-chain, BIOORG MED, 10(11), 2000, pp. 1215-1217
Authors:
Brancale, A
Srinivasan, S
McGuigan, C
Andrei, G
Snoeck, R
De Clercq, E
Balzarini, J
Citation: A. Brancale et al., Synthesis and anti-varicella-zoster virus activity of some novel bicyclic nucleoside inhibitors: effect of enhanced aqueous solubility, ANTIVIR CHE, 11(6), 2000, pp. 383-393
Authors:
McGuigan, C
Pathirana, RN
Jones, G
Andrei, G
Snoeck, R
De Clercq, E
Balzarini, J
Citation: C. Mcguigan et al., Anti-varicella-zoster virus bicyclic nucleosides: replacement of furo by pyrro base reduces antiviral potency, ANTIVIR CHE, 11(5), 2000, pp. 343-348
Authors:
McGuigan, C
Bidois, L
Hiouni, A
Ballatore, C
De Clercq, E
Balzarini, J
Citation: C. Mcguigan et al., Phosphoramidate derivatives of stavudine as inhibitors of HIV: unnatural amino acids may substitute for alanine, ANTIVIR CHE, 11(2), 2000, pp. 111-116
Authors:
McGuigan, C
Brancale, A
Barucki, H
Srinivasan, S
Jones, G
Pathirana, R
Blewett, S
Alvarez, R
Yarnold, CJ
Carangio, A
Velazquez, S
Andrei, G
Snoeck, R
De Clercq, E
Balzarini, J
Citation: C. Mcguigan et al., Fluorescent bicyclic furo pyrimidine deoxynucleoside analogs as potent andselective inhibitors of VZV and potential future drugs for the treatment of chickenpox and shingles, DRUG FUTURE, 25(11), 2000, pp. 1151-1161
Authors:
Aquaro, S
Wedgwood, O
Yarnold, C
Cahard, D
Pathinara, R
McGuigan, C
Calio', R
De Clercq, E
Balzarini, J
Perno, CF
Citation: S. Aquaro et al., Activities of masked 2 ',3 '-dideoxynucleoside monophosphate derivatives against human immunodeficiency virus in resting macrophages, ANTIM AG CH, 44(1), 2000, pp. 173-177
Authors:
McGuigan, C
Barucki, H
Blewett, S
Carangio, A
Erichsen, JT
Andrei, G
Snoeck, R
De Clercq, E
Balzarini, J
Citation: C. Mcguigan et al., Highly potent and selective inhibition of varicella-zoster virus by bicyclic furopyrimidine nucleosides bearing an aryl side chain, J MED CHEM, 43(26), 2000, pp. 4993-4997
Authors:
Siddiqui, AQ
McGuigan, C
Ballatore, C
Wedgwood, O
De Clercq, E
Balzarini, J
Citation: Aq. Siddiqui et al., Simple mono-derivatisation of the aryl moiety of d4A and ddA-based phosphoramidate prodrugs significantly enhances their anti-HIV potency in cell culture., BIOORG MED, 9(17), 1999, pp. 2555-2560
Authors:
Ballatore, C
McGuigan, C
De Clercq, E
Balzarini, J
Citation: C. Ballatore et al., An in situ pig liver esterase assay as a useful predictive tool for the likely in vitro anti viral activity of phosphoramidate pro-drugs., NUCLEOS NUC, 18(4-5), 1999, pp. 967-969
Authors:
Zeller, R
Haramis, AG
Zuniga, A
McGuigan, C
Dono, R
Davidson, G
Chabanis, S
Citation: R. Zeller et al., Formin defines a large family of morphoregulatory genes and functions in establishment of the polarising region, CELL TIS RE, 296(1), 1999, pp. 85-93
Authors:
Saboulard, D
Naesens, L
Cahard, D
Salgado, A
Pathirana, R
Velazquez, S
McGuigan, C
De Clercq, E
Balzarini, J
Citation: D. Saboulard et al., Characterization of the activation pathway of phosphoramidate triester prodrugs of stavudine and zidovudine, MOLEC PHARM, 56(4), 1999, pp. 693-704
Authors:
Siddiqui, AQ
Ballatore, C
McGuigan, C
De Clercq, E
Balzarini, J
Citation: Aq. Siddiqui et al., The presence of substituents on the aryl moiety of the aryl phosphoramidate derivative of d4T enhances anti-HIV efficacy in cell culture: A structure-activity relationship, J MED CHEM, 42(3), 1999, pp. 393-399