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Results: 1-23 |
Results: 23
Synthesis of anticonvulsive AMPA antagonists: 4-oxo-10-substituted-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic acid derivatives
Authors: Stutzmann, JM Bohme, GA Boireau, A Damour, D Debono, MW Genevois-Borella, A Jimonet, P Pratt, J Randle, JCR Ribeill, Y Vuilhorgne, M Mignani, S
Citation: Jm. Stutzmann et al., Synthesis of anticonvulsive AMPA antagonists: 4-oxo-10-substituted-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic acid derivatives, BIOORG MED, 11(9), 2001, pp. 1205-1210
Bioisosteres of 9-carboxymethyl-4-oxo-imidazo[1,2-a]indeno-[1,2-e]pyrazin-2-carboxylic acid derivatives. Progress towards selective, potent in vivo AMPA antagonists with longer durations of action
Authors: Jimonet, P Bohme, GA Bouquerel, J Boireau, A Damour, D Debono, MW Genevois-Borella, A Hardy, JC Hubert, P Manfre, F Nemecek, P Pratt, J Randle, JCR Ribeill, Y Stutzmann, JM Vuilhorgne, M Mignani, S
Citation: P. Jimonet et al., Bioisosteres of 9-carboxymethyl-4-oxo-imidazo[1,2-a]indeno-[1,2-e]pyrazin-2-carboxylic acid derivatives. Progress towards selective, potent in vivo AMPA antagonists with longer durations of action, BIOORG MED, 11(2), 2001, pp. 127-132
A preparative route to ethyl 3-(2-ethoxycarbonyl-1H-imidazol-4-yl) propenoate and propanoate
Authors: Vuilhorgne, M Bouquerel, J Hardy, JC Mignani, S
Citation: M. Vuilhorgne et al., A preparative route to ethyl 3-(2-ethoxycarbonyl-1H-imidazol-4-yl) propenoate and propanoate, SYNLETT, (1), 2001, pp. 135-137
Markov chain Monte Carlo in statistical mechanics: The problem of accuracy
Authors: Mignani, S Rosa, R
Citation: S. Mignani et R. Rosa, Markov chain Monte Carlo in statistical mechanics: The problem of accuracy, TECHNOMET, 43(3), 2001, pp. 347-355
RPR 119990, a novel alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid antagonist: Synthesis, pharmacological properties, and activity in an animal model of amyotrophic lateral sclerosis
Authors: Canton, T Bohme, GA Boireau, A Bordier, F Mignani, S Jimonet, P Jahn, G Alavijeh, M Stygall, J Roberts, S Brealey, C Vuilhorgne, M Debono, MW Le Guern, S Laville, M Briet, D Roux, M Stutzmann, JM Pratt, J
Citation: T. Canton et al., RPR 119990, a novel alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid antagonist: Synthesis, pharmacological properties, and activity in an animal model of amyotrophic lateral sclerosis, J PHARM EXP, 299(1), 2001, pp. 314-322
8-Methylureido-10-amino-10-methyl-imidazo[1,2-a]indeno[1,2-e] pyrazine-4-ones: Highly in vivo potent and selective AMPA receptor antagonists
Authors: Jimonet, P Cheve, M Bohme, GA Boireau, A Damour, D Debono, MW Genevois-Borella, A Imperato, A Pratt, J Randle, JCR Ribeill, Y Stutzmann, JM Vuilhorgne, M Mignani, S
Citation: P. Jimonet et al., 8-Methylureido-10-amino-10-methyl-imidazo[1,2-a]indeno[1,2-e] pyrazine-4-ones: Highly in vivo potent and selective AMPA receptor antagonists, BIO MED CH, 8(8), 2000, pp. 2211-2217
8-Methylureido-4,5-dihyro-4-oxo-10H-imidazo[1,2-a]indeno[1,2-e]pyrazines: Highly potent in vivo AMPA antagonists
Authors: Mignani, S Bohme, GA Boireau, A Cheve, M Damour, D Debono, MW Genevois-Borella, A Imperato, A Jimonet, P Pratt, J Randle, JCR Ribeill, Y Vuilhorgne, M Stutzmann, JM
Citation: S. Mignani et al., 8-Methylureido-4,5-dihyro-4-oxo-10H-imidazo[1,2-a]indeno[1,2-e]pyrazines: Highly potent in vivo AMPA antagonists, BIOORG MED, 10(6), 2000, pp. 591-596
Synthesis and potent anticonvulsant activities of 4-oxo-imidazo[1,2-a]indeno[1,2-e]pyrazin-8-and-9-carboxylic (acetic) acid AMPA antagonists
Authors: Pratt, J Jimonet, P Bohme, GA Boireau, A Damour, D Debono, MW Genevois-Borella, A Randle, JCR Ribeill, Y Stutzmann, JM Vuilhorgne, M Mignani, S
Citation: J. Pratt et al., Synthesis and potent anticonvulsant activities of 4-oxo-imidazo[1,2-a]indeno[1,2-e]pyrazin-8-and-9-carboxylic (acetic) acid AMPA antagonists, BIOORG MED, 10(24), 2000, pp. 2749-2754
4,10-dihydro-4-oxo-4H-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic acidderivatives: Highly potent and selective AMPA receptors antagonists with in vivo activity
Authors: Stutzmann, JM Bohme, GA Boireau, A Damour, D Debono, MW Genevois-Borella, A Imperato, A Jimonet, P Pratt, J Randle, JCR Ribeill, Y Vuilhorgne, M Mignani, S
Citation: Jm. Stutzmann et al., 4,10-dihydro-4-oxo-4H-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic acidderivatives: Highly potent and selective AMPA receptors antagonists with in vivo activity, BIOORG MED, 10(10), 2000, pp. 1133-1137
Stereoselective cycloaddition of monosubstituted ketene to a methyl glyoxylate- and threonine-derived imine: Synthesis of optically pure beta-lactamic alpha-amino ester with high functionality.
Authors: Mignani, S Mouysset, D Le Roy, I Stella, L
Citation: S. Mignani et al., Stereoselective cycloaddition of monosubstituted ketene to a methyl glyoxylate- and threonine-derived imine: Synthesis of optically pure beta-lactamic alpha-amino ester with high functionality., SYN COMMUN, 30(20), 2000, pp. 3685-3691
Indeno[1,2-b]pyrazin-2,3-diones: A new class of antagonists at the glycinesite of the NMDA receptor with potent in vivo activity
Authors: Jimonet, P Ribeill, Y Bohme, GA Boireau, A Cheve, M Damour, D Doble, A Genevois-Borella, A Herman, F Imperato, A Le Guern, S Manfre, F Pratt, J Randle, JCR Stutzmann, JM Mignani, S
Citation: P. Jimonet et al., Indeno[1,2-b]pyrazin-2,3-diones: A new class of antagonists at the glycinesite of the NMDA receptor with potent in vivo activity, J MED CHEM, 43(12), 2000, pp. 2371-2381
Synthesis of six-membered silaheterocycles by the ring enlargement of 1,1-diphenyl-1-silacyclopent-3-ene
Authors: Keglevich, G Trecska, M Ujszaszy, K Ludanyi, K Szollosy, A Toke, L Mignani, S
Citation: G. Keglevich et al., Synthesis of six-membered silaheterocycles by the ring enlargement of 1,1-diphenyl-1-silacyclopent-3-ene, HETEROAT CH, 10(2), 1999, pp. 171-175
Spiro-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one derivatives are mixed AMPAand NMDA glycine-site antagonists active in vivo.
Authors: Jimonet, P Boireau, A Cheve, M Damour, D Genevois-Borella, A Imperato, A Pratt, J Randle, JCR Ribeill, Y Stutzmann, JM Mignani, S
Citation: P. Jimonet et al., Spiro-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one derivatives are mixed AMPAand NMDA glycine-site antagonists active in vivo., BIOORG MED, 9(20), 1999, pp. 2921-2926
cis- and trans-3-(3-indolyl)proline derivatives as conformationally restricted analogues of tryptophan
Authors: Damour, D Pulicani, JP Vuilhorgne, M Mignani, S
Citation: D. Damour et al., cis- and trans-3-(3-indolyl)proline derivatives as conformationally restricted analogues of tryptophan, SYNLETT, (6), 1999, pp. 786-788
A convenient synthetic route to macrocyclic cis-3-phenylproline derivatives as mimics of sandostatin (R)
Authors: Damour, D Doerflinger, G Pantel, G Labaudiniere, R Leconte, JP Sable, S Vuilhorgne, M Mignani, S
Citation: D. Damour et al., A convenient synthetic route to macrocyclic cis-3-phenylproline derivatives as mimics of sandostatin (R), SYNLETT, (2), 1999, pp. 189-192
A preparative route to fused indeno[1,2-e][1,2,4]-triazolo[4,3-a]pyrazin-4-ones
Authors: Ribeill, Y Genevois-Borella, A Vuilhorgne, M Mignani, S
Citation: Y. Ribeill et al., A preparative route to fused indeno[1,2-e][1,2,4]-triazolo[4,3-a]pyrazin-4-ones, HETEROCYCLE, 51(12), 1999, pp. 2977-2982
An efficient preparative route to fused imidazo[1,2-a]pyrazin-4-one derivatives
Authors: Damour, D Aloup, JC Barreau, M Genevois-Borella, A Jimonet, P Leconte, JP Ribeill, Y Vuilhorgne, M Mignani, S
Citation: D. Damour et al., An efficient preparative route to fused imidazo[1,2-a]pyrazin-4-one derivatives, HETEROCYCLE, 50(1), 1999, pp. 259-267
A convenient method for the preparation of 3-azetidinylidene acetic acid
Authors: Vuilhorgne, M Commercon, A Mignani, S
Citation: M. Vuilhorgne et al., A convenient method for the preparation of 3-azetidinylidene acetic acid, CHEM LETT, (7), 1999, pp. 605-606
Synthesis and pharmacological properties of 5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, a new competitive AMPA/KA receptor antagonist
Authors: Mignani, S Aloup, JC Barreau, M Blanchard, JC Bohme, GA Boireau, A Damour, D Debono, MW Dubroeucq, MC Genevois-Borella, A Imperato, A Jimonet, P Pratt, J Randle, JCR Reibaud, M Ribeill, Y Stutzmann, JM
Citation: S. Mignani et al., Synthesis and pharmacological properties of 5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, a new competitive AMPA/KA receptor antagonist, DRUG DEV R, 48(3), 1999, pp. 121-129
Synthesis of azepane scaffolds on solid support for combinatorial chemistry
Authors: Gauzy, L Le Merrer, Y Depezay, JC Clerc, F Mignani, S
Citation: L. Gauzy et al., Synthesis of azepane scaffolds on solid support for combinatorial chemistry, TETRAHEDR L, 40(33), 1999, pp. 6005-6008
Synthesis of C-2-symmetric bis(cyclic isothioureas) as potent inhibitors of glycosidases
Authors: Gauzy, L Le Merrer, Y Depezay, JC Damour-Barbalat, D Mignani, S
Citation: L. Gauzy et al., Synthesis of C-2-symmetric bis(cyclic isothioureas) as potent inhibitors of glycosidases, TETRAHEDR L, 40(19), 1999, pp. 3705-3708
Synthesis of novel proline and gamma-lactam derivatives as non-peptide mimics of Somatostatin/Sandostatin (R)
Authors: Damour, D Herman, F Labaudiniere, R Pantel, G Vuilhorgne, M Mignani, S
Citation: D. Damour et al., Synthesis of novel proline and gamma-lactam derivatives as non-peptide mimics of Somatostatin/Sandostatin (R), TETRAHEDRON, 55(33), 1999, pp. 10135-10154
Riluzole Series. Synthesis and in vivo "antiglutamate" activity of 6-substituted-2-benzothiazolamines and 3-substituted-2-imino-benzothiazalines
Authors: Jimonet, P Audiau, F Barreau, M Blanchard, JC Boireau, A Bour, Y Coleno, MA Doble, A Doerflinger, G Hu, CD Donat, MH Duchesne, JM Ganil, P Gueremy, C Honore, E Just, B Kerphirique, R Gontier, S Hubert, P Laduron, PM Le Blevec, J Meunier, R Miquet, JM Nemecek, C Pasquet, M Piot, O Pratt, J Rataud, J Reibaud, N Stutzmann, JM Mignani, S
Citation: P. Jimonet et al., Riluzole Series. Synthesis and in vivo "antiglutamate" activity of 6-substituted-2-benzothiazolamines and 3-substituted-2-imino-benzothiazalines, J MED CHEM, 42(15), 1999, pp. 2828-2843
Risultati: 1-23 |