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Results: 1-25/70
Authors:
NEIDLE S
Citation: S. Neidle, NEW INSIGHTS INTO SEQUENCE-DEPENDENT DNA-STRUCTURE, Nature structural biology, 5(9), 1998, pp. 754-756
Authors:
KELLAND LR
GOWAN SM
PERRY PJ
NEIDLE S
Citation: Lr. Kelland et al., INHIBITION OF HUMAN TELOMERASE AND GROWTH OF HUMAN OVARIAN-CARCINOMA CELL-LINES BY 2,6-DISUBSTITUTED AMIDO-ANTHRACENE-9,10 DIONES, Annals of oncology, 9, 1998, pp. 540-540
Authors:
NUNN CM
NEIDLE S
Citation: Cm. Nunn et S. Neidle, STRUCTURE OF THE DNA DECAMER D(GGCAATTGCG) CONTAINS BOTH MAJOR-GROOVEAND MINOR-GROOVE BINDING G.(G.C) BASE TRIPLETS, Acta crystallographica. Section D, Biological crystallography, 54, 1998, pp. 577-583
Authors:
GUERRI A
SIMPSON IJ
NEIDLE S
Citation: A. Guerri et al., VISUALIZATION OF EXTENSIVE WATER RIBBONS AND NETWORKS IN A DNA MINOR-GROOVE DRUG COMPLEX, Nucleic acids research, 26(12), 1998, pp. 2873-2878
Authors:
ADZHUBEI IA
ADZHUBEI AA
NEIDLE S
Citation: Ia. Adzhubei et al., AN INTEGRATED SEQUENCE-STRUCTURE DATABASE INCORPORATING MATCHING MESSENGER-RNA SEQUENCE, AMINO-ACID-SEQUENCE AND PROTEIN 3-DIMENSIONAL STRUCTURE DATA, Nucleic acids research, 26(1), 1998, pp. 327-331
Authors:
MIAH A
REESE CB
SONG QL
STURDY Z
NEIDLE S
SIMPSON IJ
READ M
RAYNER E
Citation: A. Miah et al., 2',3'-ANHYDROURIDINE - A USEFUL SYNTHETIC INTERMEDIATE, Journal of the Chemical Society. Perkin transactions. I (Print), (19), 1998, pp. 3277-3283
Authors:
NEIDLE S
NUNN CM
Citation: S. Neidle et Cm. Nunn, CRYSTAL-STRUCTURES OF NUCLEIC-ACIDS AND THEIR DRUG COMPLEXES, Natural product reports, 15(1), 1998, pp. 1-15
Authors:
NEIDLE S
GAFFNEY PRJ
REESE CB
Citation: S. Neidle et al., MYOINOSITOL 1,3,5-BICYCLIC PHOSPHATE, Acta crystallographica. Section C, Crystal structure communications, 54, 1998, pp. 1191-1192
Authors:
PERRY PJ
RESZKA AP
WOOD AA
READ MA
GOWAN SM
DOSANJH HS
TRENT JO
JENKINS TC
KELLAND LR
NEIDLE S
Citation: Pj. Perry et al., HUMAN TELOMERASE INHIBITION BY REGIOISOMERIC DISUBSTITUTED AMIDOANTHRACENE-9,10-DIONES, Journal of medicinal chemistry, 41(24), 1998, pp. 4873-4884
Authors:
VENITT S
CROFTONSLEIGH C
AGBANDJE M
JENKINS TC
NEIDLE S
Citation: S. Venitt et al., ANTHRACENE-9,10-DIONES AS POTENTIAL ANTICANCER AGENTS - BACTERIAL MUTATION STUDIES OF AMIDO-SUBSTITUTED DERIVATIVES REVEAL AN UNEXPECTED LACK OF MUTAGENICITY, Journal of medicinal chemistry, 41(19), 1998, pp. 3748-3752
Authors:
PERRY PJ
GOWAN SM
RESZKA AP
POLUCCI P
JENKINS TC
KELLAND LR
NEIDLE S
Citation: Pj. Perry et al., 1,4-DISUBSTITUTED AND 2,6-DISUBSTITUTED AMIDOANTHRACENE-9,10-DIONE DERIVATIVES AS INHIBITORS OF HUMAN TELOMERASE, Journal of medicinal chemistry, 41(17), 1998, pp. 3253-3260
Authors:
KELLAND LR
GOWAN SM
PERRY PJ
NEIDLE S
Citation: Lr. Kelland et al., 2.6-DISUBSTITUTED AMIDO-ANTHRACENE-9,10 DIONES - SMALL-MOLECULE INHIBITORS OF HUMAN TELOMERASE, British Journal of Cancer, 78, 1998, pp. 64-64
Authors:
JONES DM
SUEIRASDIAZ J
SZELKE M
LECKIE BJ
BEATTIE SR
MORTON J
NEIDLE S
KURODA R
Citation: Dm. Jones et al., NEW RENIN INHIBITORS CONTAINING NOVEL ANALOGS OF STATINE, The journal of peptide research, 50(2), 1997, pp. 109-121
Authors:
BAXTER AD
BHOGAL R
BIRD JB
BUCKLEY GM
GREGORY DS
HEDGER PC
MANALLACK DT
MASSIL T
MINTON KJ
MONTANA JG
NEIDLE S
OWEN DA
WATSON RJ
Citation: Ad. Baxter et al., MERCAPTOACYL MATRIX METALLOPROTEINASE INHIBITORS - THE EFFECT OF SUBSTITUTION AT THE MERCAPTOACYL MOIETY, Bioorganic & medicinal chemistry letters, 7(21), 1997, pp. 2765-2770
Authors:
NEIDLE S
KELLAND LR
TRENT JO
SIMPSON IJ
BOYKIN DW
KUMAR A
WILSON WD
Citation: S. Neidle et al., CYTOTOXICITY OF BIS(PHENYLAMIDINIUM)FURAN ALKYL DERIVATIVES IN HUMAN TUMOR-CELL LINES - RELATION TO DNA MINOR-GROOVE BINDING, Bioorganic & medicinal chemistry letters, 7(11), 1997, pp. 1403-1408
Authors:
NUNN CM
NEIDLE S
Citation: Cm. Nunn et S. Neidle, STRUCTURE OF THE A-DNA OCTAMER D(GGCATGCC), Acta crystallographica. Section D, Biological crystallography, 53, 1997, pp. 269-273
Authors:
CLARK GR
BOYKIN DW
CZARNY A
NEIDLE S
Citation: Gr. Clark et al., STRUCTURE OF A BIS-AMIDINIUM DERIVATIVE OF HOECHST-33258 COMPLEXED TODODECANUCLEOTIDE D(CGCGAATTCGCG)2 - THE ROLE OF HYDROGEN-BONDING IN MINOR-GROOVE DRUG-DNA RECOGNITION, Nucleic acids research, 25(8), 1997, pp. 1510-1515
Authors:
CASSIDY SA
SLICKERS P
TRENT JO
CAPALDI DC
ROSELT PD
REESE CB
NEIDLE S
FOX KR
Citation: Sa. Cassidy et al., RECOGNITION OF GC BASE-PAIRS BY TRIPLEX FORMING OLIGONUCLEOTIDES CONTAINING NUCLEOSIDES DERIVED FROM 2-AMINOPYRIDINE, Nucleic acids research, 25(24), 1997, pp. 4891-4898
Authors:
NEIDLE S
Citation: S. Neidle, RECENT DEVELOPMENTS IN TRIPLE-HELIX REGULATION OF GENE-EXPRESSION, Anti-cancer drug design, 12(5), 1997, pp. 433-442
Authors:
BURKE DF
LAUGHTON CA
NEIDLE S
Citation: Df. Burke et al., HOMOLOGY MODELING OF THE ENZYME P450 17-ALPHA-HYDROXYLASE 17,2O-LYASE- A TARGET FOR PROSTATE-CANCER CHEMOTHERAPY - FROM THE CRYSTAL-STRUCTURE OF P450BM-3/, Anti-cancer drug design, 12(2), 1997, pp. 113-123
Authors:
WOOD AA
NUNN CM
TRENT JO
NEIDLE S
Citation: Aa. Wood et al., SEQUENCE-DEPENDENT CROSSED HELIX PACKING IN THE CRYSTAL-STRUCTURE OF A B-DNA DECAMER YIELDS A DETAILED MODEL FOR THE HOLLIDAY JUNCTION, Journal of Molecular Biology, 269(5), 1997, pp. 827-841
Authors:
SUN DY
THOMPSON B
CATHERS BE
SALAZAR M
KERWIN SM
TRENT JO
JENKINS TC
NEIDLE S
HURLEY LH
Citation: Dy. Sun et al., INHIBITION OF HUMAN TELOMERASE BY A G-QUADRUPLEX-INTERACTIVE COMPOUND, Journal of medicinal chemistry, 40(14), 1997, pp. 2113-2116
Authors:
NUNN CM
TRENT JO
NEIDLE S
Citation: Cm. Nunn et al., A MODEL FOR THE [C-G-CENTER-DOT-C](N) TRIPLE-HELIX DERIVED FROM OBSERVATION OF THE C+-G-CENTER-DOT-C BASE TRIPLET IN A CRYSTAL-STRUCTURE(), FEBS letters, 416(1), 1997, pp. 86-89
Authors:
NEIDLE S
Citation: S. Neidle, CRYSTALLOGRAPHIC INSIGHTS INTO DNA MINOR-GROOVE RECOGNITION BY DRUGS, Biopolymers, 44(1), 1997, pp. 105-121
Authors:
SCHNEIDER B
NEIDLE S
BERMAN HM
Citation: B. Schneider et al., CONFORMATIONS OF THE SUGAR-PHOSPHATE BACKBONE IN HELICAL DNA CRYSTAL-STRUCTURES, Biopolymers, 42(1), 1997, pp. 113-124