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Results: 1-8 |
Results: 8
Structural basis of the thrombin selectivity of a ligand that contains theconstrained arginine mimic (2S)-2-amino-(3S)-3-(1-carbamimidoyl-piperidin-3-yl)-propanoic acid at P1
Authors: Narasimhan, LS Rubin, JR Holland, DR Plummer, JS Rapundalo, ST Edmunds, JE St-Denis, Y Siddiqui, MA Humblet, C
Citation: Ls. Narasimhan et al., Structural basis of the thrombin selectivity of a ligand that contains theconstrained arginine mimic (2S)-2-amino-(3S)-3-(1-carbamimidoyl-piperidin-3-yl)-propanoic acid at P1, J MED CHEM, 43(3), 2000, pp. 361-368
Rational design, synthesis, and biological activity of benzoxazinones as novel factor Xa inhibitors
Authors: Dudley, DA Bunker, AM Chi, LG Cody, WL Holland, DR Ignasiak, DP Janiczek-Dolphin, N McClanahan, TB Mertz, TE Narasimhan, LS Rapundalo, ST Trautschold, JA Van Huis, CA Edmunds, JJ
Citation: Da. Dudley et al., Rational design, synthesis, and biological activity of benzoxazinones as novel factor Xa inhibitors, J MED CHEM, 43(22), 2000, pp. 4063-4070
Benzenesulfonamide derivatives of 2-substituted 4H-3,1-benzoxazin-4-ones and benzthiazin-4-ones as inhibitors of complement Clr protease
Authors: Plummer, JS Cai, CM Hays, SJ Gilmore, JL Emmerling, MR Michael, W Narasimhan, LS Watson, MD Wang, K Nath, R Evans, LM Jaen, JC
Citation: Js. Plummer et al., Benzenesulfonamide derivatives of 2-substituted 4H-3,1-benzoxazin-4-ones and benzthiazin-4-ones as inhibitors of complement Clr protease, BIOORG MED, 9(6), 1999, pp. 815-820
Potent and selective bicyclic lactam inhibitors of thrombin: Part 3: P1 ' modifications
Authors: Plummer, JS Berryman, KA Cai, CM Cody, WL DiMaio, J Doherty, AM Eaton, S Edmunds, JJ Holland, DR Lafleur, D Levesque, S Narasimhan, LS Rubin, JR Rapundalo, T Siddiqui, MA Susser, A St-Denis, Y Winocour, P
Citation: Js. Plummer et al., Potent and selective bicyclic lactam inhibitors of thrombin: Part 3: P1 ' modifications, BIOORG MED, 9(6), 1999, pp. 835-840
The design of potent and selective inhibitors of thrombin utilizing a piperazinedione template: Part 1
Authors: Cody, WL Cai, CM Doherty, AM Edmunds, JJ He, JX Narasimhan, LS Plummer, JS Rapundalo, ST Rubin, JR Van Huis, CA St-Denis, Y Winocour, PD Siddiqui, MA
Citation: Wl. Cody et al., The design of potent and selective inhibitors of thrombin utilizing a piperazinedione template: Part 1, BIOORG MED, 9(17), 1999, pp. 2497-2502
The design of potent and selective inhibitors of thrombin utilizing a piperazinedione template: Part 2
Authors: Cody, WL Augelli-Szafran, CE Berryman, KA Cai, CM Doherty, AM Edmunds, JJ He, JX Narasimhan, LS Penvose-Yi, J Plummer, JS Rapundalo, ST Rubin, JR Van Huis, CA Leblond, L Winocour, PD Siddiqui, MA
Citation: Wl. Cody et al., The design of potent and selective inhibitors of thrombin utilizing a piperazinedione template: Part 2, BIOORG MED, 9(17), 1999, pp. 2503-2508
Potent and selective bicyclic lactam inhibitors of thrombin: Part 2: P1 modifications
Authors: Plummer, JS Berryman, KA Cai, C Cody, WL DiMaio, J Doherty, AM Edmunds, JJ He, JX Holland, DR Levesque, S Kent, DR Narasimhan, LS Rubin, JR Rapundalo, ST Siddiqui, MA Susser, AJ St-Denis, Y Winocour, PD
Citation: Js. Plummer et al., Potent and selective bicyclic lactam inhibitors of thrombin: Part 2: P1 modifications, BIOORG MED, 8(23), 1998, pp. 3409-3414
Potent bicyclic lactam inhibitors of thrombin: Part I: P3 modifications
Authors: St-Denis, Y Augelli-Szafran, CE Bachand, B Berryman, KA DiMaio, J Doherty, AM Edmunds, JJ Leblond, L Levesque, S Narasimhan, LS Penvose-Yi, JR Rubin, JR Tarazi, M Winocour, PD Siddiqui, MA
Citation: Y. St-denis et al., Potent bicyclic lactam inhibitors of thrombin: Part I: P3 modifications, BIOORG MED, 8(22), 1998, pp. 3193-3198
Risultati: 1-8 |