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Results: 1-22 |
Results: 22
INVOLVEMENT OF HUMAN AND MURINE TUMOR CYTOCHROME-P450 IN BIOREDUCTIONOF AQ4N
Authors: RALEIGH SM MURRAY MM ROBSON T GALLAGHER R MCKEOWN S PATTERSON LH
Citation: Sm. Raleigh et al., INVOLVEMENT OF HUMAN AND MURINE TUMOR CYTOCHROME-P450 IN BIOREDUCTIONOF AQ4N, Annals of oncology, 9, 1998, pp. 515-515
INVOLVEMENT OF HUMAN CYTOCHROMES P450 (CYP) IN THE REDUCTIVE METABOLISM OF AQ4N, A HYPOXIA ACTIVATED ANTHRAQUINONE DI-N-OXIDE PRODRUG
Authors: RALEIGH SM WANOGHO E BURKE MD MCKEOWN SR PATTERSON LH
Citation: Sm. Raleigh et al., INVOLVEMENT OF HUMAN CYTOCHROMES P450 (CYP) IN THE REDUCTIVE METABOLISM OF AQ4N, A HYPOXIA ACTIVATED ANTHRAQUINONE DI-N-OXIDE PRODRUG, International journal of radiation oncology, biology, physics, 42(4), 1998, pp. 763-767
ENHANCEMENT OF CYCLOPHOSPHAMIDE ANTITUMOR-ACTIVITY WITH BIOREDUCTIVE DRUGS AQ4N AND TIRAPAZAMINE
Authors: MCKEOWN SR FRIERY O GALLAGHER R MURRAY M CLARKE C PATTERSON LH HIRST DG
Citation: Sr. Mckeown et al., ENHANCEMENT OF CYCLOPHOSPHAMIDE ANTITUMOR-ACTIVITY WITH BIOREDUCTIVE DRUGS AQ4N AND TIRAPAZAMINE, British Journal of Cancer, 78, 1998, pp. 45-45
INCREASED EXPRESSION OF CYTOCHROME-P450 ISOFORMS IN MOUSE-TUMORS AND THEIR ROLE IN THE ENHANCED ACTIVATION OF THE BIOREDUCTIVE DRUG, AQ4N
Authors: MURRAY MM ROBSON T GALLAGHER R PATTERSON LH HIRST DG MCKEOWN SR
Citation: Mm. Murray et al., INCREASED EXPRESSION OF CYTOCHROME-P450 ISOFORMS IN MOUSE-TUMORS AND THEIR ROLE IN THE ENHANCED ACTIVATION OF THE BIOREDUCTIVE DRUG, AQ4N, British Journal of Cancer, 78, 1998, pp. 710-710
REDUCTION OF THE INDOLOQUINONE ANTICANCER DRUG EO9 BY PURIFIED DT-DIAPHORASE - A DETAILED KINETIC-STUDY AND ANALYSIS OF METABOLITES
Authors: BAILEY SM LEWIS AD KNOX RJ PATTERSON LH FISHER GR WORKMAN P
Citation: Sm. Bailey et al., REDUCTION OF THE INDOLOQUINONE ANTICANCER DRUG EO9 BY PURIFIED DT-DIAPHORASE - A DETAILED KINETIC-STUDY AND ANALYSIS OF METABOLITES, Biochemical pharmacology, 56(5), 1998, pp. 613-621
DNA TOPOISOMERASE II-DEPENDENT CYTOTOXICITY OF ALKYLAMINOANTHRAQUINONES AND THEIR N-OXIDES
Authors: SMITH PJ BLUNT NJ DESNOYERS R GILES Y PATTERSON LH
Citation: Pj. Smith et al., DNA TOPOISOMERASE II-DEPENDENT CYTOTOXICITY OF ALKYLAMINOANTHRAQUINONES AND THEIR N-OXIDES, Cancer chemotherapy and pharmacology, 39(5), 1997, pp. 455-461
FLOW CYTOMETRIC ANALYSIS AND CONFOCAL IMAGING OF ANTICANCER ALKYLAMINOANTHRAQUINONES AND THEIR N-OXIDES IN INTACT HUMAN-CELLS USING 647-NM KRYPTON LASER EXCITATION
Authors: SMITH PJ DESNOYERS R BLUNT N GILES Y PATTERSON LH WATSON JV
Citation: Pj. Smith et al., FLOW CYTOMETRIC ANALYSIS AND CONFOCAL IMAGING OF ANTICANCER ALKYLAMINOANTHRAQUINONES AND THEIR N-OXIDES IN INTACT HUMAN-CELLS USING 647-NM KRYPTON LASER EXCITATION, Cytometry, 27(1), 1997, pp. 43-53
RATIONALIZATION OF THE C-S LYASE ACTIVITY OF ASPARTATE AMINO TRANSFERASE
Authors: TEESDALESPITTLE PH ADCOCK HJ PATTERSON LH BUCKBERRY LD
Citation: Ph. Teesdalespittle et al., RATIONALIZATION OF THE C-S LYASE ACTIVITY OF ASPARTATE AMINO TRANSFERASE, Biochemical Society transactions, 24(1), 1996, pp. 141-141
INTERACTION OF THE NOVEL BIOREDUCTIVE DRUG AQ4N WITH RADIATION IN BDFMICE IMPLANTED WITH THE T50 80 TUMOR/
Authors: FRIERY OP HEJMADI MV MCINTYRE IA MCALEER JJA PATTERSON LH MCKEOWN SR
Citation: Op. Friery et al., INTERACTION OF THE NOVEL BIOREDUCTIVE DRUG AQ4N WITH RADIATION IN BDFMICE IMPLANTED WITH THE T50 80 TUMOR/, Irish journal of medical science, 165(4), 1996, pp. 310-310
COMPARISON OF THE CARDIOTOXICITY OF NEW ANTHRAQUINONE ANTITUMOR AGENTS AND THEIR N-OXIDES PRODRUGS WITH DOXORUBICIN AND EPIRUBICIN USING ISOLATED RAT CARDIAC MYOCYTES
Authors: RAHAL MK IRVING G PATTERSON LH BROWN JE
Citation: Mk. Rahal et al., COMPARISON OF THE CARDIOTOXICITY OF NEW ANTHRAQUINONE ANTITUMOR AGENTS AND THEIR N-OXIDES PRODRUGS WITH DOXORUBICIN AND EPIRUBICIN USING ISOLATED RAT CARDIAC MYOCYTES, British Journal of Pharmacology, 117, 1996, pp. 274-274
EVIDENCE FOR A THERAPEUTIC GAIN WHEN AQ4N OR TIRAPAZAMINE IS COMBINEDWITH RADIATION
Authors: MCKEOWN SR FRIERY OP MCINTYRE IA HEJMADI MV PATTERSON LH HIRST DG
Citation: Sr. Mckeown et al., EVIDENCE FOR A THERAPEUTIC GAIN WHEN AQ4N OR TIRAPAZAMINE IS COMBINEDWITH RADIATION, British Journal of Cancer, 74, 1996, pp. 39-42
TERTIARY AMINE N-OXIDES AS BIOREDUCTIVE DRUGS - DACA N-OXIDE, NITRACRINE N-OXIDE AND AQ4N
Authors: WILSON WR DENNY WA PULLEN SM THOMPSON KM LI AE PATTERSON LH LEE HH
Citation: Wr. Wilson et al., TERTIARY AMINE N-OXIDES AS BIOREDUCTIVE DRUGS - DACA N-OXIDE, NITRACRINE N-OXIDE AND AQ4N, British Journal of Cancer, 74, 1996, pp. 43-47
DNA-DAMAGE FOLLOWING COMBINATION OF RADIATION WITH THE BIOREDUCTIVE DRUG AQ4N - POSSIBLE SELECTIVE TOXICITY TO OXIC AND HYPOXIC TUMOR-CELLS
Authors: HEJMADI MV MCKEOWN SR FRIERY OP MCINTYRE IA PATTERSON LH HIRST DG
Citation: Mv. Hejmadi et al., DNA-DAMAGE FOLLOWING COMBINATION OF RADIATION WITH THE BIOREDUCTIVE DRUG AQ4N - POSSIBLE SELECTIVE TOXICITY TO OXIC AND HYPOXIC TUMOR-CELLS, British Journal of Cancer, 73(4), 1996, pp. 499-505
GENERATION OF A FREE-RADICAL FROM CALPHOSTIN-C BY MICROSOMAL CYTOCHROME-P450 REDUCTASE IN RAT AND HUMAN LIVER
Authors: PATTERSON LH JONES S GESCHER A
Citation: Lh. Patterson et al., GENERATION OF A FREE-RADICAL FROM CALPHOSTIN-C BY MICROSOMAL CYTOCHROME-P450 REDUCTASE IN RAT AND HUMAN LIVER, Biochemical pharmacology, 51(5), 1996, pp. 599-603
OFFENSIVE SECRETORY SODS
Authors: BROPHY PM PATTERSON LH PRITCHARD DI
Citation: Pm. Brophy et al., OFFENSIVE SECRETORY SODS, Parasitology today, 11(3), 1995, pp. 112-112
SECRETORY NEMATODE SOD - OFFENSIVE OR DEFENSIVE
Authors: BROPHY PM PATTERSON LH PRITCHARD DL
Citation: Pm. Brophy et al., SECRETORY NEMATODE SOD - OFFENSIVE OR DEFENSIVE, International journal for parasitology, 25(7), 1995, pp. 865-866
AQ4N - AN ALKYLAMINOANTHRAQUINONE N-OXIDE SHOWING BIOREDUCTIVE POTENTIAL AND POSITIVE INTERACTION WITH RADIATION IN-VIVO
Authors: MCKEOWN SR HEJMADI MV MCINTYRE IA MCALEER JJA PATTERSON LH
Citation: Sr. Mckeown et al., AQ4N - AN ALKYLAMINOANTHRAQUINONE N-OXIDE SHOWING BIOREDUCTIVE POTENTIAL AND POSITIVE INTERACTION WITH RADIATION IN-VIVO, British Journal of Cancer, 72(1), 1995, pp. 76-81
GLUTATHIONE-S-TRANSFERASE (GST) EXPRESSION IN THE HUMAN HOOKWORM NECATOR-AMERICANUS - POTENTIAL ROLES FOR EXCRETORY-SECRETORY FORMS OF GST
Authors: BROPHY PM PATTERSON LH BROWN A PRITCHARD DI
Citation: Pm. Brophy et al., GLUTATHIONE-S-TRANSFERASE (GST) EXPRESSION IN THE HUMAN HOOKWORM NECATOR-AMERICANUS - POTENTIAL ROLES FOR EXCRETORY-SECRETORY FORMS OF GST, Acta Tropica, 59(3), 1995, pp. 259-263
ALIPHATIC AMINE N-OXIDES OF DNA-BINDING AGENTS AS BIOREDUCTIVE DRUGS
Authors: PATTERSON LH CRAVEN MR FISHER GR TEESDALESPITTLE P
Citation: Lh. Patterson et al., ALIPHATIC AMINE N-OXIDES OF DNA-BINDING AGENTS AS BIOREDUCTIVE DRUGS, Oncology research, 6(10-11), 1994, pp. 533-538
PREPARATION AND STABILITY OF LIPOSOME-ENCAPSULATED DOXORUBICIN AND MITOXANTRONE AND THEIR INTERNALIZATION BY MURINE PERITONEAL-MACROPHAGES
Authors: LILLEY JC PATTERSON LH TAYLOR MJ
Citation: Jc. Lilley et al., PREPARATION AND STABILITY OF LIPOSOME-ENCAPSULATED DOXORUBICIN AND MITOXANTRONE AND THEIR INTERNALIZATION BY MURINE PERITONEAL-MACROPHAGES, International journal of pharmaceutics, 107(2), 1994, pp. 149-157
UPTAKE AND INTRACELLULAR-DISTRIBUTION OF ANTICANCER DRUGS STUDIED BY DIRECT IMAGING AND FLOW-CYTOMETRY
Authors: SMITH PJ FOX ME PATTERSON LH
Citation: Pj. Smith et al., UPTAKE AND INTRACELLULAR-DISTRIBUTION OF ANTICANCER DRUGS STUDIED BY DIRECT IMAGING AND FLOW-CYTOMETRY, Bone marrow transplantation, 12, 1993, pp. 190000156-190000157
A COMPARISON OF FREE-RADICAL FORMATION BY QUINONE ANTITUMOR AGENTS INMCF-7 CELLS AND THE ROLE OF NAD(P)H (QUINONE-ACCEPTOR) OXIDOREDUCTASE(DT-DIAPHORASE)
Authors: FISHER GR PATTERSON LH GUTIERREZ PL
Citation: Gr. Fisher et al., A COMPARISON OF FREE-RADICAL FORMATION BY QUINONE ANTITUMOR AGENTS INMCF-7 CELLS AND THE ROLE OF NAD(P)H (QUINONE-ACCEPTOR) OXIDOREDUCTASE(DT-DIAPHORASE), Chemico-biological interactions, 88(2-3), 1993, pp. 137-153
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