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Results: 1-25/31
Authors:
Kakolyris, S
Giatromanolaki, A
Koukourakis, M
Powis, G
Souglakos, J
Sivridis, E
Georgoulias, V
Gatter, KC
Harris, AL
Citation: S. Kakolyris et al., Thioredoxin expression is associated with lymph node status and prognosis in early operable non-small cell lung cancer, CLIN CANC R, 7(10), 2001, pp. 3087-3091
Authors:
Powis, G
Montfort, WR
Citation: G. Powis et Wr. Montfort, Properties and biological activities of thioredoxins, ANN R BIO B, 30, 2001, pp. 421-455
Authors:
Xie, W
Peng, HR
Kim, DI
Kunkel, M
Powis, G
Zalkow, LH
Citation: W. Xie et al., Structure-activity relationship of aza-steroids as PI-PLC inhibitors, BIO MED CH, 9(5), 2001, pp. 1073-1083
Authors:
Hu, YH
Meuillet, EJ
Berggren, M
Powis, G
Kozikowski, AP
Citation: Yh. Hu et al., 3-deoxy-3-substituted-D-myo-inositol imidazolyl ether lipid phosphates andcarbonate as inhibitors of the phosphatidylinositol 3-kinase pathway and cancer cell growth, BIOORG MED, 11(2), 2001, pp. 173-176
Authors:
Wipf, P
Hopkins, TD
Jung, JK
Rodriguez, S
Birmingham, A
Southwick, EC
Lazo, JS
Powis, G
Citation: P. Wipf et al., New inhibitors of the thioredoxin-thioredoxin reductase system based on a naphthoquinone spiroketal natural product lead, BIOORG MED, 11(19), 2001, pp. 2637-2641
Authors:
Powis, G
Montfort, WR
Citation: G. Powis et Wr. Montfort, Properties and biological activities of thioredoxins, ANN R PHARM, 41, 2001, pp. 261-295
Authors:
Rong, SB
Hu, YH
Enyedy, I
Powis, G
Meuillet, EJ
Wu, XW
Wang, RX
Wang, SM
Kozikowski, AP
Citation: Sb. Rong et al., Molecular modeling studies of the Akt PH domain and its interaction with phosphoinositides, J MED CHEM, 44(6), 2001, pp. 898-908
Authors:
Peng, HR
Xie, WG
Otterness, DM
Cogswell, JP
McConnell, RT
Carter, HL
Powis, G
Abraham, RT
Zalkow, LH
Citation: Hr. Peng et al., Syntheses and biological activities of a novel group of steroidal derived inhibitors for human CDC25A protein phosphatase, J MED CHEM, 44(5), 2001, pp. 834-848
Authors:
Tome, ME
Baker, AF
Powis, G
Payne, CM
Briehl, MM
Citation: Me. Tome et al., Catalase-overexpressing thymocytes are resistant to glucocorticoid-inducedapoptosis and exhibit increased net tumor growth, CANCER RES, 61(6), 2001, pp. 2766-2773
Authors:
Berggren, MI
Husbeck, B
Samulitis, B
Baker, AF
Gallegos, A
Powis, G
Citation: Mi. Berggren et al., Thioredoxin peroxidase-1 (peroxiredoxin-1) is increased in thioredoxin-1 transfected cells and results in enhanced protection against apoptosis caused by hydrogen peroxide but not by other agents including dexamethasone, etoposide, and doxorubicin, ARCH BIOCH, 392(1), 2001, pp. 103-109
Authors:
Berggren, MM
Powis, G
Citation: Mm. Berggren et G. Powis, Alternative splicing is associated with decreased expression of the redox proto-oncogene thioredoxin-1 in human cancers, ARCH BIOCH, 389(1), 2001, pp. 144-149
Authors:
Qiao, LX
Hu, YH
Nan, FJ
Powis, G
Kozikowski, AP
Citation: Lx. Qiao et al., A versatile approach to PI(3,4)P-2, PI(4,5)P-2, and PI(3,4,5)P-3 from L-(-)-quebrachitol, ORG LETT, 2(2), 2000, pp. 115-117
Authors:
Xie, WG
Peng, HR
Zalkow, LH
Li, YH
Zhu, C
Powis, G
Kunkel, M
Citation: Wg. Xie et al., 3 beta-hydroxy-6-aza-cholestane and related analogues as phosphatidylinositol specific phospholipase C (PI-PLC) inhibitors with antitumor activity, BIO MED CH, 8(4), 2000, pp. 699-706
Authors:
Peng, HR
Xie, WG
Kim, DI
Zalkow, LH
Powis, G
Otterness, DM
Abraham, RT
Citation: Hr. Peng et al., Steroidal derived acids as inhibitors of human Cdc25A protein phosphatase, BIO MED CH, 8(2), 2000, pp. 299-306
Authors:
Powis, G
Mustacich, D
Coon, A
Citation: G. Powis et al., The role of the redox protein thioredoxin in cell growth and cancer, FREE RAD B, 29(3-4), 2000, pp. 312-322
Authors:
Engman, L
Kanda, T
Gallegos, A
Williams, R
Powis, G
Citation: L. Engman et al., Water-soluble organotellurium compounds inhibit thioredoxin reductase and the growth of human cancer cells, ANTI-CAN DR, 15(5), 2000, pp. 323-330
Authors:
Mustacich, D
Powis, G
Citation: D. Mustacich et G. Powis, Thioredoxin reductase, BIOCHEM J, 346, 2000, pp. 1-8
Authors:
Grogan, TM
Fenoglio-Prieser, C
Zeheb, R
Bellamy, W
Frutiger, Y
Vela, E
Stemmerman, G
Macdonald, J
Richter, L
Gallegos, A
Powis, G
Citation: Tm. Grogan et al., Thioredoxin, a putative oncogene product, is overexpressed in gastric carcinoma and associated with increased proliferation and increased cell survival, HUMAN PATH, 31(4), 2000, pp. 475-481
Authors:
Hu, YH
Meuillet, EJ
Qiao, LX
Berggren, MM
Powis, G
Kozikowski, AP
Citation: Yh. Hu et al., Synthesis and Akt inhibitory properties of a 1D-3,4-dideoxyphosphatidylinositol ether lipid, TETRAHEDR L, 41(39), 2000, pp. 7415-7418
Authors:
Hu, YH
Qiao, LX
Wang, SM
Rong, SB
Meuillet, EJ
Berggren, M
Gallegos, A
Powis, G
Kozikowski, AP
Citation: Yh. Hu et al., 3-(Hydroxymethyl)-bearing phosphatidylinositol ether lipid analogues and carbonate surrogates block PI3-K, Akt, and cancer cell growth, J MED CHEM, 43(16), 2000, pp. 3045-3051
Authors:
Freemerman, AJ
Powis, G
Citation: Aj. Freemerman et G. Powis, A redox-inactive thioredoxin reduces growth and enhances apoptosis in WEHI7.2 cells, BIOC BIOP R, 274(1), 2000, pp. 136-141
Authors:
Baker, A
Dos Santos, B
Powis, G
Citation: A. Baker et al., Redox control of caspase-3 activity by thioredoxin and other reduced proteins, BIOC BIOP R, 268(1), 2000, pp. 78-81
Authors:
Lemke, LE
Paine-Murrieta, GD
Taylor, CW
Powis, G
Citation: Le. Lemke et al., Wortmannin inhibits the growth of mammary tumors despite the existence of a novel wortmannin-insensitive phosphatidylinositol-3-kinase, CANC CHEMOT, 44(6), 1999, pp. 491-497
Authors:
Kirkpatrick, DL
Watson, S
Kunkel, M
Fletcher, S
Ulhaq, S
Powis, G
Citation: Dl. Kirkpatrick et al., Parallel syntheses of disulfide inhibitors of the thioredoxin redox systemas potential antitumor agents, ANTI-CAN DR, 14(5), 1999, pp. 421-432
Authors:
Yeates, LC
Gallegos, A
Kozikowski, AP
Powis, G
Citation: Lc. Yeates et al., Down regulation of the expression of the p110, p85 and p55 subunits of phosphatidylinositol 3-kinase during colon cancer cell anchorage-independent growth, ANTICANC R, 19(5B), 1999, pp. 4171-4176