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Results: 1-15 |
Results: 15
ACAT INHIBITORS - EVOLUTION FROM CHOLESTEROL-ABSORPTION INHIBITORS TOANTIATHEROSCLEROTIC AGENTS
Authors: ROTH BD
Citation: Bd. Roth, ACAT INHIBITORS - EVOLUTION FROM CHOLESTEROL-ABSORPTION INHIBITORS TOANTIATHEROSCLEROTIC AGENTS, Drug discovery today, 3(1), 1998, pp. 19-25
INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS - SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF NOVEL SERIES OF SULFONAMIDES, ACYLPHOSPHONAMIDES AND ACYLPHOSPHORAMIDATES
Authors: LEE HT ROARK WH PICARD JA SLISKOVIC DR ROTH BD STANFIELD RL HAMELEHLE KL BOUSLEY RF KRAUSE BR
Citation: Ht. Lee et al., INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYLTRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS - SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF NOVEL SERIES OF SULFONAMIDES, ACYLPHOSPHONAMIDES AND ACYLPHOSPHORAMIDATES, Bioorganic & medicinal chemistry letters, 8(3), 1998, pp. 289-294
INSTALLATION OF 12B-SUBSTITUENTS ONTO INDOLO[2,3-A]QUINOLIZIDIN-2-ONES AND APPLICATION TO PENTACYCLIC ALKALOID SYNTHESIS
Authors: LI JJ TRIVEDI BK RUBIN JR ROTH BD
Citation: Jj. Li et al., INSTALLATION OF 12B-SUBSTITUENTS ONTO INDOLO[2,3-A]QUINOLIZIDIN-2-ONES AND APPLICATION TO PENTACYCLIC ALKALOID SYNTHESIS, Tetrahedron letters, 39(34), 1998, pp. 6111-6114
NOVEL NONPEPTIDE CCK-B ANTAGONISTS - DESIGN AND DEVELOPMENT OF QUINAZOLINONE DERIVATIVES AS POTENT, SELECTIVE, AND ORALLY-ACTIVE CCK-E ANTAGONISTS
Authors: PADIA JK FIELD M HINTON J MEECHAM K PABLO J PINNOCK R ROTH BD SINGH L SUMANCHAUHAN N TRIVEDI BK WEBDALE L
Citation: Jk. Padia et al., NOVEL NONPEPTIDE CCK-B ANTAGONISTS - DESIGN AND DEVELOPMENT OF QUINAZOLINONE DERIVATIVES AS POTENT, SELECTIVE, AND ORALLY-ACTIVE CCK-E ANTAGONISTS, Journal of medicinal chemistry, 41(7), 1998, pp. 1042-1049
ALPHA-SUBSTITUTED MALONESTER AMIDES - TOOLS TO DEFINE THE RELATIONSHIP BETWEEN ACAT INHIBITION AND ADRENAL TOXICITY
Authors: SLISKOVIC DR PICARD JA OBRIEN PM LIAO P ROARK WH ROTH BD ANDERSON MA MUELLER SB BOCAN TMA BOUSLEY RF HAMELEHLE KL HOMAN R REINDEL JF STANFIELD RL TURLUCK D KRAUSE BR
Citation: Dr. Sliskovic et al., ALPHA-SUBSTITUTED MALONESTER AMIDES - TOOLS TO DEFINE THE RELATIONSHIP BETWEEN ACAT INHIBITION AND ADRENAL TOXICITY, Journal of medicinal chemistry, 41(5), 1998, pp. 682-690
SAR STUDY OF THE INDOLE MOIETY OF CI-988, A POTENT AND SELECTIVE CCK-B ANTAGONIST
Authors: AUGELLISZAFRAN CE PURCHASE TS ROTH BD TAIT B TRIVEDI BK WILSON M SUMANCHAUHAN N WEBDALE L
Citation: Ce. Augelliszafran et al., SAR STUDY OF THE INDOLE MOIETY OF CI-988, A POTENT AND SELECTIVE CCK-B ANTAGONIST, Bioorganic & medicinal chemistry letters, 7(15), 1997, pp. 2009-2014
CATECHOL BASED INHIBITORS OF 15-LIPOXYGENASE
Authors: TAIT BD DYER RD AUERBACH BJ BORNEMEIER D GUILDSZAMARKA L OXENDER M ROTH BD TRIVEDI BK CORNICELLI JA
Citation: Bd. Tait et al., CATECHOL BASED INHIBITORS OF 15-LIPOXYGENASE, Bioorganic & medicinal chemistry letters, 6(1), 1996, pp. 93-96
INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS - CI-1011 - AN ACYL SULFAMATE WITH UNIQUE CHOLESTEROL-LOWERING ACTIVITY IN ANIMALS FED NONCHOLESTEROL-SUPPLEMENTED DIETS
Authors: LEE HT SLISKOVIC DR PICARD JA ROTH BD WIERENGA W HICKS JL BOUSLEY RF HAMELEHLE KL HOMAN R SPEYER C STANFIELD RL KRAUSE BR
Citation: Ht. Lee et al., INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS - CI-1011 - AN ACYL SULFAMATE WITH UNIQUE CHOLESTEROL-LOWERING ACTIVITY IN ANIMALS FED NONCHOLESTEROL-SUPPLEMENTED DIETS, Journal of medicinal chemistry, 39(26), 1996, pp. 5031-5034
INHIBITORS OF ACYL-COA-CHOLESTEROL ACYLTRANSFERASE (ACAT) .15. SULFONYLUREA INHIBITORS WITH EXCELLENT HYPOCHOLESTEROLEMIC ACTIVITY IN-VIVO
Authors: ROTH BD ROARK WH PICARD JA STANFIELD RL BOUSLEY RF ANDERSON MK HAMELEHLE KL HOMAN R KRAUSE BR
Citation: Bd. Roth et al., INHIBITORS OF ACYL-COA-CHOLESTEROL ACYLTRANSFERASE (ACAT) .15. SULFONYLUREA INHIBITORS WITH EXCELLENT HYPOCHOLESTEROLEMIC ACTIVITY IN-VIVO, Bioorganic & medicinal chemistry letters, 5(20), 1995, pp. 2367-2370
INHIBITORS OF ACYL-COA-CHOLESTEROL ACYLTRANSFERASE .10. IMIDAZOLIDINONES AND PYRAZOLONES AS NOVEL ACAT INHIBITORS - CHEMISTRY AND BIOLOGICAL-ACTIVITY
Authors: AUGELLISZAFRAN CE ROTH BD ESSENBURG A HAMELEHLE KL KRAUSE BR STANFIELD RL
Citation: Ce. Augelliszafran et al., INHIBITORS OF ACYL-COA-CHOLESTEROL ACYLTRANSFERASE .10. IMIDAZOLIDINONES AND PYRAZOLONES AS NOVEL ACAT INHIBITORS - CHEMISTRY AND BIOLOGICAL-ACTIVITY, Bioorganic & medicinal chemistry letters, 4(9), 1994, pp. 1095-1100
INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS .8. INCORPORATION OF AMIDE OR AMINE FUNCTIONALITIES INTO A SERIES OF DISUBSTITUTED UREAS AND CARBAMATES - EFFECTS ON ACAT INHIBITION IN-VITRO AND EFFICACY IN-VIVO
Authors: OBRIEN PM SLISKOVIC DR BLANKLEY CJ ROTH BD WILSON MW HAMELEHLE KL KRAUSE BR STANFIELD RL
Citation: Pm. Obrien et al., INHIBITORS OF ACYL-COA-CHOLESTEROL O-ACYL TRANSFERASE (ACAT) AS HYPOCHOLESTEROLEMIC AGENTS .8. INCORPORATION OF AMIDE OR AMINE FUNCTIONALITIES INTO A SERIES OF DISUBSTITUTED UREAS AND CARBAMATES - EFFECTS ON ACAT INHIBITION IN-VITRO AND EFFICACY IN-VIVO, Journal of medicinal chemistry, 37(12), 1994, pp. 1810-1822
ANTIATHEROSCLEROTIC ACTIVITY OF INHIBITORS OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME-A REDUCTASE IN CHOLESTEROL-FED RABBITS - A BIOCHEMICAL AND MORPHOLOGICAL EVALUATION
Authors: BOCAN TMA MAZUR MJ MUELLER SB BROWN EQ SLISKOVIC DR OBRIEN PM CRESWELL MW LEE H UHLENDORF PD ROTH BD NEWTON RS
Citation: Tma. Bocan et al., ANTIATHEROSCLEROTIC ACTIVITY OF INHIBITORS OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME-A REDUCTASE IN CHOLESTEROL-FED RABBITS - A BIOCHEMICAL AND MORPHOLOGICAL EVALUATION, Atherosclerosis, 111(1), 1994, pp. 127-142
SYNTHESIS AND SAR STUDY OF NOVEL CCK-B ANTAGONISTS
Authors: PADIA JK BOLTON GL HILL D HORWELL DC ROTH BD TRIVEDI BK
Citation: Jk. Padia et al., SYNTHESIS AND SAR STUDY OF NOVEL CCK-B ANTAGONISTS, Bioorganic & medicinal chemistry letters, 3(12), 1993, pp. 2805-2810
INHIBITORS OF ACYL-COA CHOLESTEROL ACYLTRANSFERASE .5. IDENTIFICATIONAND STRUCTURE-ACTIVITY-RELATIONSHIPS OF NOVEL BETA-KETOAMIDES AS HYPOCHOLESTEROLEMIC AGENTS
Authors: AUGELLISZAFRAN CE BLANKLEY CJ ROTH BD TRIVEDI BK BOUSLEY RF ESSENBURG AD HAMELEHLE KL KRAUSE BR STANFIELD RL
Citation: Ce. Augelliszafran et al., INHIBITORS OF ACYL-COA CHOLESTEROL ACYLTRANSFERASE .5. IDENTIFICATIONAND STRUCTURE-ACTIVITY-RELATIONSHIPS OF NOVEL BETA-KETOAMIDES AS HYPOCHOLESTEROLEMIC AGENTS, Journal of medicinal chemistry, 36(20), 1993, pp. 2943-2949
INHIBITORS OF ACYL-COA CHOLESTEROL ACYLTRANSFERASE (ACAT) .2. MODIFICATION OF FATTY-ACID ANILIDE ACAT INHIBITORS - BIOISOSTERIC REPLACEMENTOF THE AMIDE BOND
Authors: ROARK WH ROTH BD HOLMES A TRIVEDI BK KIEFT KA ESSENBURG AD KRAUSE BR STANFIELD RL
Citation: Wh. Roark et al., INHIBITORS OF ACYL-COA CHOLESTEROL ACYLTRANSFERASE (ACAT) .2. MODIFICATION OF FATTY-ACID ANILIDE ACAT INHIBITORS - BIOISOSTERIC REPLACEMENTOF THE AMIDE BOND, Journal of medicinal chemistry, 36(11), 1993, pp. 1662-1668
Risultati: 1-15 |