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Results: 1-15 |
Results: 15
NANOMOLAR INHIBITORS FOR 2 DISTINCT BIOLOGICAL TARGET FAMILIES FROM ASINGLE SYNTHETIC SEQUENCE - A NEXT STEP IN COMBINATORIAL LIBRARY DESIGN
Authors: BURNS CJ GRONEBERG RD SALVINO JM MCGEEHAN G CONDON SM MORRIS R MORRISSETTE M MATHEW R DARNBROUGH S NEUENSCHWANDER K SCOTESE A DJURIC SW ULLRICH J LABAUDINIERE R
Citation: Cj. Burns et al., NANOMOLAR INHIBITORS FOR 2 DISTINCT BIOLOGICAL TARGET FAMILIES FROM ASINGLE SYNTHETIC SEQUENCE - A NEXT STEP IN COMBINATORIAL LIBRARY DESIGN, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 37(20), 1998, pp. 2848-2850
NOVEL SAFETY-CATCH LINKER AND ITS APPLICATION WITH A UGI DE-BOC/CYCLIZATION (UDC) STRATEGY TO ACCESS CARBOXYLIC-ACIDS, 1,4-BENZODIAZEPINES,DIKETOPIPERAZINES, KETOPIPERAZINES AND DIHYDROQUINOXALINONES/
Authors: HULME C PENG J MORTON G SALVINO JM HERPIN T LABAUDINIERE R
Citation: C. Hulme et al., NOVEL SAFETY-CATCH LINKER AND ITS APPLICATION WITH A UGI DE-BOC/CYCLIZATION (UDC) STRATEGY TO ACCESS CARBOXYLIC-ACIDS, 1,4-BENZODIAZEPINES,DIKETOPIPERAZINES, KETOPIPERAZINES AND DIHYDROQUINOXALINONES/, Tetrahedron letters, 39(40), 1998, pp. 7227-7230
PYRIDAZINODIAZEPINES AS A HIGH-AFFINITY, P-2-P-3 PEPTIDOMIMETIC CLASSOF INTERLEUKIN-1-BETA-CONVERTING ENZYME-INHIBITOR
Authors: DOLLE RE PRASAD CVC PROUTY CP SALVINO JM AWAD MMA SCHMIDT SJ HOYER D ROSS TM GRAYBILL TL SPEIER GJ UHL J MILLER BE HELASZEK CT ATOR MA
Citation: Re. Dolle et al., PYRIDAZINODIAZEPINES AS A HIGH-AFFINITY, P-2-P-3 PEPTIDOMIMETIC CLASSOF INTERLEUKIN-1-BETA-CONVERTING ENZYME-INHIBITOR, Journal of medicinal chemistry, 40(13), 1997, pp. 1941-1946
FIRST EXAMPLES OF PEPTIDOMIMETIC INHIBITORS OF INTERLEUKIN-1-BETA CONVERTING-ENZYME
Authors: DOLLE RE PROUTY CP PRASAD CVC COOK E SAHA A ROSS TM SALVINO JM HELASZEK CT ATOR MA
Citation: Re. Dolle et al., FIRST EXAMPLES OF PEPTIDOMIMETIC INHIBITORS OF INTERLEUKIN-1-BETA CONVERTING-ENZYME, Journal of medicinal chemistry, 39(13), 1996, pp. 2438-2440
STRUCTURAL AND STEREOCHEMICAL REQUIREMENTS OF TIME-DEPENDENT INACTIVATORS OF THE INTERLEUKIN-1-BETA CONVERTING-ENZYME
Authors: PRASAD CVC PROUTY CP HOYER D ROSS TM SALVINO JM AWAD M GRAYBILL TL SCHMIDT SJ OSIFO IK DOLLE RE HELASZEK CT MILLER RE ATOR MA
Citation: Cvc. Prasad et al., STRUCTURAL AND STEREOCHEMICAL REQUIREMENTS OF TIME-DEPENDENT INACTIVATORS OF THE INTERLEUKIN-1-BETA CONVERTING-ENZYME, Bioorganic & medicinal chemistry letters, 5(4), 1995, pp. 315-318
STRUCTURE-ACTIVITY-RELATIONSHIPS OF NONPEPTIDE BRADYKININ B-2 RECEPTOR ANTAGONISTS
Authors: SALVINO JM SEOANE PR DOUTY BD AWAD MA HOYER D ROSS TM DOLLE RE HOUCK WT FAUNCE DM SAWUTZ DG
Citation: Jm. Salvino et al., STRUCTURE-ACTIVITY-RELATIONSHIPS OF NONPEPTIDE BRADYKININ B-2 RECEPTOR ANTAGONISTS, Bioorganic & medicinal chemistry letters, 5(4), 1995, pp. 357-362
SYNTHESIS OF NONPEPTIDE BRADYKININ B-2 RECEPTOR ANTAGONISTS
Authors: DOUTY BD SALVINO JM SEOANE PR DOLLE RE
Citation: Bd. Douty et al., SYNTHESIS OF NONPEPTIDE BRADYKININ B-2 RECEPTOR ANTAGONISTS, Bioorganic & medicinal chemistry letters, 5(4), 1995, pp. 363-366
ACE-INHIBITORS AS A TEMPLATE FOR THE DESIGN OF BRADYKININ B-2 RECEPTOR ANTAGONISTS
Authors: HOYER D AWAD MMA SALVINO JM SEOANE PR DOLLE RE HOUCK WT SAWUTZ DG
Citation: D. Hoyer et al., ACE-INHIBITORS AS A TEMPLATE FOR THE DESIGN OF BRADYKININ B-2 RECEPTOR ANTAGONISTS, Bioorganic & medicinal chemistry letters, 5(4), 1995, pp. 367-370
PHARMACOLOGY AND STRUCTURE ACTIVITY RELATIONSHIPS OF THE NONPEPTIDE BRADYKININ RECEPTOR ANTAGONIST WIN-64338
Authors: SAWUTZ DG SALVINO JM DOLLE RE SEOANE PR FARMER SG
Citation: Dg. Sawutz et al., PHARMACOLOGY AND STRUCTURE ACTIVITY RELATIONSHIPS OF THE NONPEPTIDE BRADYKININ RECEPTOR ANTAGONIST WIN-64338, Canadian journal of physiology and pharmacology, 73(7), 1995, pp. 805-811
THE NONPEPTIDE WIN-64338 IS A BRADYKININ B-2 RECEPTOR ANTAGONIST
Authors: SAWUTZ DG SALVINO JM DOLLE RE CASIANO F WARD SJ HOUCK WT FAUNCE DM DOUTY BD BAIZMAN E AWAD MMA MARCEAU F SEOANE PR
Citation: Dg. Sawutz et al., THE NONPEPTIDE WIN-64338 IS A BRADYKININ B-2 RECEPTOR ANTAGONIST, Proceedings of the National Academy of Sciences of the United Statesof America, 91(11), 1994, pp. 4693-4697
BRADYKININ RECEPTOR TYPES AND B-2 SUBTYPES
Authors: REGOLI D GOBEIL F NGUYEN QT JUKIC D SEOANE PR SALVINO JM SAWUTZ DG
Citation: D. Regoli et al., BRADYKININ RECEPTOR TYPES AND B-2 SUBTYPES, Life sciences, 55(10), 1994, pp. 735-749
EFFECTS OF PEPTIDE AND NONPEPTIDE ANTAGONISTS OF BRADYKININ B-2 RECEPTORS ON THE VENOCONSTRICTOR ACTION OF BRADYKININ
Authors: MARCEAU F LEVESQUE L DRAPEAU G RIOUX F SALVINO JM WOLFE HR SEOANE PR SAWUTZ DG
Citation: F. Marceau et al., EFFECTS OF PEPTIDE AND NONPEPTIDE ANTAGONISTS OF BRADYKININ B-2 RECEPTORS ON THE VENOCONSTRICTOR ACTION OF BRADYKININ, The Journal of pharmacology and experimental therapeutics, 269(3), 1994, pp. 1136-1143
ASPARTYL -PHENYL-3-(TRIFLUOROMETHYL)PYRAZOL-5-YL)OXY)METHYL KETONES AS INTERLEUKIN-1-BETA CONVERTING-ENZYME INHIBITORS - SIGNIFICANCE OF THE P-1 AND P-3 AMIDO NITROGENS FOR ENZYME-PEPTIDE INHIBITOR BINDING
Authors: DOLLE RE SINGH J RINKER J HOYER D PRASAD CVC GRAYBILL TL SALVINO JM HELASZEK CT MILLER RE ATOR MA
Citation: Re. Dolle et al., ASPARTYL -PHENYL-3-(TRIFLUOROMETHYL)PYRAZOL-5-YL)OXY)METHYL KETONES AS INTERLEUKIN-1-BETA CONVERTING-ENZYME INHIBITORS - SIGNIFICANCE OF THE P-1 AND P-3 AMIDO NITROGENS FOR ENZYME-PEPTIDE INHIBITOR BINDING, Journal of medicinal chemistry, 37(23), 1994, pp. 3863-3866
SYNTHESIS, CHARACTERIZATION, AND CONFORMATIONAL-ANALYSIS OF THE D L-TIC(7) STEREOISOMERS OF THE BRADYKININ RECEPTOR ANTAGONIST D-ARG(0)[HYP(3),THI(5),D-TIC(7),OIC(8)]BRADYKININ/
Authors: SAWUTZ DG SALVINO JM SEOANE PR DOUTY BD HOUCK WT BOBKO MA DOLEMAN MS DOLLE RE WOLFE HR
Citation: Dg. Sawutz et al., SYNTHESIS, CHARACTERIZATION, AND CONFORMATIONAL-ANALYSIS OF THE D L-TIC(7) STEREOISOMERS OF THE BRADYKININ RECEPTOR ANTAGONIST D-ARG(0)[HYP(3),THI(5),D-TIC(7),OIC(8)]BRADYKININ/, Biochemistry, 33(9), 1994, pp. 2373-2379
DESIGN OF POTENT NONPEPTIDE COMPETITIVE ANTAGONISTS OF THE HUMAN BRADYKININ-B2 RECEPTOR
Authors: SALVINO JM SEOANE PR DOUTY BD AWAD MMA DOLLE RE HOUCK WT FAUNCE DM SAWUTZ DG
Citation: Jm. Salvino et al., DESIGN OF POTENT NONPEPTIDE COMPETITIVE ANTAGONISTS OF THE HUMAN BRADYKININ-B2 RECEPTOR, Journal of medicinal chemistry, 36(17), 1993, pp. 2583-2584
Risultati: 1-15 |