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Results: 1-13 |
Results: 13
DESIGN AND CONSTRUCTION OF NOVEL THROMBIN INHIBITORS FEATURING P-3-P-4 QUATERNARY LACTAM DIPEPTIDE SURROGATES
Authors: SEMPLE JE
Citation: Je. Semple, DESIGN AND CONSTRUCTION OF NOVEL THROMBIN INHIBITORS FEATURING P-3-P-4 QUATERNARY LACTAM DIPEPTIDE SURROGATES, Bioorganic & medicinal chemistry letters, 8(18), 1998, pp. 2501-2506
EFFICIENT CONSTRUCTION OF NOVEL QUATERNARY LACTAM DIPEPTIDE SURROGATES
Authors: SEMPLE JE
Citation: Je. Semple, EFFICIENT CONSTRUCTION OF NOVEL QUATERNARY LACTAM DIPEPTIDE SURROGATES, Tetrahedron letters, 39(37), 1998, pp. 6645-6648
A PRACTICAL AND EFFICIENT SYNTHETIC ROUTE TO DIHYDROPIPERCIDE AND PIPERCIDE
Authors: ROTHERHAM LW SEMPLE JE
Citation: Lw. Rotherham et Je. Semple, A PRACTICAL AND EFFICIENT SYNTHETIC ROUTE TO DIHYDROPIPERCIDE AND PIPERCIDE, Journal of organic chemistry, 63(19), 1998, pp. 6667-6672
HIGHLY SELECTIVE MECHANISM-BASED THROMBIN INHIBITORS - STRUCTURES OF THROMBIN AND TRYPSIN INHIBITED WITH RIGID PEPTIDYL ALDEHYDES
Authors: KRISHNAN R ZHANG E HAKANSSON K ARNI RK TULINSKY A LIMWILBY MSL LEVY OE SEMPLE JE BRUNCK TK
Citation: R. Krishnan et al., HIGHLY SELECTIVE MECHANISM-BASED THROMBIN INHIBITORS - STRUCTURES OF THROMBIN AND TRYPSIN INHIBITED WITH RIGID PEPTIDYL ALDEHYDES, Biochemistry, 37(35), 1998, pp. 12094-12103
SYNTHESIS AND BIOLOGICAL-ACTIVITY OF P-2-P-4 AZAPEPTIDOMIMETIC P-1-ARGININAL AND P-1-KETOARGININAMIDE DERIVATIVES - A NOVEL CLASS OF SERINE-PROTEASE INHIBITORS
Authors: SEMPLE JE ROWLEY DC BRUNCK TK RIPKA WC
Citation: Je. Semple et al., SYNTHESIS AND BIOLOGICAL-ACTIVITY OF P-2-P-4 AZAPEPTIDOMIMETIC P-1-ARGININAL AND P-1-KETOARGININAMIDE DERIVATIVES - A NOVEL CLASS OF SERINE-PROTEASE INHIBITORS, Bioorganic & medicinal chemistry letters, 7(3), 1997, pp. 315-320
RATIONAL DESIGN, SYNTHESIS, AND SERINE-PROTEASE INHIBITORY ACTIVITY OF A NOVEL P-1-ARGININAL DERIVATIVE FEATURING A CONFORMATIONALLY CONSTRAINED P-2-P-3-BICYCLIC LACTAM MOIETY
Authors: TAMURA SY GOLDMAN EA BRUNCK TK RIPKA WC SEMPLE JE
Citation: Sy. Tamura et al., RATIONAL DESIGN, SYNTHESIS, AND SERINE-PROTEASE INHIBITORY ACTIVITY OF A NOVEL P-1-ARGININAL DERIVATIVE FEATURING A CONFORMATIONALLY CONSTRAINED P-2-P-3-BICYCLIC LACTAM MOIETY, Bioorganic & medicinal chemistry letters, 7(3), 1997, pp. 331-336
RATIONAL DESIGN AND SYNTHESIS OF A NOVEL, SELECTIVE CLASS OF THROMBININHIBITORS - P-1-ARGININAL DERIVATIVES INCORPORATING P-3-P-4 QUATERNARY LACTAM DIPEPTIDE SURROGATES
Authors: SEMPLE JE MINAMI NK TAMURA SY BRUNCK TK NUTT RF RIPKA WC
Citation: Je. Semple et al., RATIONAL DESIGN AND SYNTHESIS OF A NOVEL, SELECTIVE CLASS OF THROMBININHIBITORS - P-1-ARGININAL DERIVATIVES INCORPORATING P-3-P-4 QUATERNARY LACTAM DIPEPTIDE SURROGATES, Bioorganic & medicinal chemistry letters, 7(18), 1997, pp. 2421-2426
DESIGN AND SYNTHESIS OF A NOVEL CLASS OF THROMBIN INHIBITORS INCORPORATING HETEROCYCLIC DIPEPTIDE SURROGATES
Authors: TAMURA SY SEMPLE JE REINER JE GOLDMAN EA BRUNCK TK LIMWILBY MS CARPENTER SH ROTE WE OLDESHULTE GL RICHARD BM NUTT RF RIPKA WC
Citation: Sy. Tamura et al., DESIGN AND SYNTHESIS OF A NOVEL CLASS OF THROMBIN INHIBITORS INCORPORATING HETEROCYCLIC DIPEPTIDE SURROGATES, Bioorganic & medicinal chemistry letters, 7(12), 1997, pp. 1543-1548
FACILE ACCESS TO NOVEL 1,4-DIHYDROXYNAPHTHALENE-2,3-DICARBOXIMIDES AND HETEROFUSED ANALOGS
Authors: MURRAY WM SEMPLE JE
Citation: Wm. Murray et Je. Semple, FACILE ACCESS TO NOVEL 1,4-DIHYDROXYNAPHTHALENE-2,3-DICARBOXIMIDES AND HETEROFUSED ANALOGS, Synthesis, (10), 1996, pp. 1180
AN EFFICIENT SYNTHETIC ROUTE TO ETHYL YDROXY-1,3(2H,4H)-DIOXOISOQUINOLINE-4-CARBOXYLATES
Authors: SEMPLE JE RYDZEWSKI RM GARDNER G
Citation: Je. Semple et al., AN EFFICIENT SYNTHETIC ROUTE TO ETHYL YDROXY-1,3(2H,4H)-DIOXOISOQUINOLINE-4-CARBOXYLATES, Journal of organic chemistry, 61(22), 1996, pp. 7967-7972
POTENT AND SELECTIVE THROMBIN INHIBITORS INCORPORATING THE CONSTRAINED ARGININE MIMIC L-3-PIPERIDYL(N-GUANIDINO)ALANINE AT P-1
Authors: LEVY OE SEMPLE JE LIM ML REINER J ROTE WE DEMPSEY E RICHARD BM ZHANG E TULINSKY A RIPKA WC NUTT RF
Citation: Oe. Levy et al., POTENT AND SELECTIVE THROMBIN INHIBITORS INCORPORATING THE CONSTRAINED ARGININE MIMIC L-3-PIPERIDYL(N-GUANIDINO)ALANINE AT P-1, Journal of medicinal chemistry, 39(23), 1996, pp. 4527-4530
DESIGN, SYNTHESIS, AND EVOLUTION OF A NOVEL, SELECTIVE, AND ORALLY BIOAVAILABLE CLASS OF THROMBIN INHIBITORS - P1-ARGININAL DERIVATIVES INCORPORATING P3-P4 LACTAM SULFONAMIDE MOIETIES
Authors: SEMPLE JE ROWLEY DC BRUNCK TK HAUONG T MINAMI NK OWENS TD TAMURA SY GOLDMAN EA SIEV DV ARDECKY RJ CARPENTER SH GE Y RICHARD BM NOLAN TG HAKANSON K TULINSKY A NUTT RF RIPKA WC
Citation: Je. Semple et al., DESIGN, SYNTHESIS, AND EVOLUTION OF A NOVEL, SELECTIVE, AND ORALLY BIOAVAILABLE CLASS OF THROMBIN INHIBITORS - P1-ARGININAL DERIVATIVES INCORPORATING P3-P4 LACTAM SULFONAMIDE MOIETIES, Journal of medicinal chemistry, 39(23), 1996, pp. 4531-4536
A CONCISE SYNTHESIS OF PELLITORINE
Authors: SEMPLE JE
Citation: Je. Semple, A CONCISE SYNTHESIS OF PELLITORINE, Organic preparations and procedures international, 27(5), 1995, pp. 582-586
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