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Results: 1-22 |
Results: 22
Synthesis and unusual chemical reactivity of certain novel 4,5-disubstituted 7-benzylpyrrolo[2,3-d][1,2,3]triazines
Authors: Migawa, MT Townsend, LB
Citation: Mt. Migawa et Lb. Townsend, Synthesis and unusual chemical reactivity of certain novel 4,5-disubstituted 7-benzylpyrrolo[2,3-d][1,2,3]triazines, J ORG CHEM, 66(14), 2001, pp. 4776-4782
Dimetalation of pyrazines. A one-pot synthesis of multisubstituted pyrazine C-nucleosides
Authors: Liu, WM Wise, DS Townsend, LB
Citation: Wm. Liu et al., Dimetalation of pyrazines. A one-pot synthesis of multisubstituted pyrazine C-nucleosides, J ORG CHEM, 66(14), 2001, pp. 4783-4786
Acid-catalyzed dehydrative cyclization of 4-(D-galacto-pentitol-1-yl)-2-phenyl-2H-1,2,3-triazole. Synthesis and anomeric configuration of D-lyxo-C-nucleoside analogs
Authors: Sallam, MAE Megid, SMEA Townsend, LB
Citation: Mae. Sallam et al., Acid-catalyzed dehydrative cyclization of 4-(D-galacto-pentitol-1-yl)-2-phenyl-2H-1,2,3-triazole. Synthesis and anomeric configuration of D-lyxo-C-nucleoside analogs, CARBOHY RES, 330(1), 2001, pp. 53-63
Synthesis of 4-substituted imidazo[4,5-d][1,2,3]triazine (2-azapurine)nucleosides
Authors: Krawczyk, S Migawa, MT Drach, JC Townsend, LB
Citation: S. Krawczyk et al., Synthesis of 4-substituted imidazo[4,5-d][1,2,3]triazine (2-azapurine)nucleosides, NUCLEOS NUC, 19(1-2), 2000, pp. 39-68
Synthesis and evaluation of a series of 2 '-deoxy analogues of the antiviral agent 5,6-dichloro-2-isopropylamino-1-(beta-L-ribofuranosyl)-1H-benzimidazole (1263W94)
Authors: Chan, JH Chamberlain, SD Biron, KK Davis, MG Harvey, RJ Selleseth, DW Dornsife, RE Dark, EH Frick, LW Townsend, LB Drach, JC Koszalka, GW
Citation: Jh. Chan et al., Synthesis and evaluation of a series of 2 '-deoxy analogues of the antiviral agent 5,6-dichloro-2-isopropylamino-1-(beta-L-ribofuranosyl)-1H-benzimidazole (1263W94), NUCLEOS NUC, 19(1-2), 2000, pp. 101-123
Design, synthesis, and antiviral evaluation of 2-deoxy-D-ribosides of substituted benzimidazoles as potential agents for human cytomegalovirus infections
Authors: Zou, RM Kawashima, E Freeman, GA Koszalke, GW Drach, JC Townsend, LB
Citation: Rm. Zou et al., Design, synthesis, and antiviral evaluation of 2-deoxy-D-ribosides of substituted benzimidazoles as potential agents for human cytomegalovirus infections, NUCLEOS NUC, 19(1-2), 2000, pp. 125-153
Differences in DNA packaging genes and sensitivity to benzimidazole ribonucleosides between human cytomegalovirus strains AD169 and Towne
Authors: Krosky, PM Ptak, RG Underwood, MR Biron, KK Townsend, LB Drach, JC
Citation: Pm. Krosky et al., Differences in DNA packaging genes and sensitivity to benzimidazole ribonucleosides between human cytomegalovirus strains AD169 and Towne, ANTIVIR CHE, 11(5), 2000, pp. 349-352
Design, synthesis, and biological evaluation of tricyclic nucleosides (dimensional probes) as analogues of certain antiviral polyhalogenated benzimidazole ribonucleosides
Authors: Zhu, ZJ Lippa, B Drach, JC Townsend, LB
Citation: Zj. Zhu et al., Design, synthesis, and biological evaluation of tricyclic nucleosides (dimensional probes) as analogues of certain antiviral polyhalogenated benzimidazole ribonucleosides, J MED CHEM, 43(12), 2000, pp. 2430-2437
Deoxy sugar analogues of triciribine: Correlation of antiviral and antiproliferative activity with intracellular phosphorylation
Authors: Porcari, AR Ptak, RG Borysko, KZ Breitenbach, JM Vittori, S Wotring, LL Drach, JC Townsend, LB
Citation: Ar. Porcari et al., Deoxy sugar analogues of triciribine: Correlation of antiviral and antiproliferative activity with intracellular phosphorylation, J MED CHEM, 43(12), 2000, pp. 2438-2448
Synthesis and antiviral evaluation of trisubstituted indole N-nucleosides as analogues of 2,5,6-trichloro-1-(beta-D-ribofuranosyl)benzimidazole (TCRB)
Authors: Chen, JJ Wei, Y Drach, JC Townsend, LB
Citation: Jj. Chen et al., Synthesis and antiviral evaluation of trisubstituted indole N-nucleosides as analogues of 2,5,6-trichloro-1-(beta-D-ribofuranosyl)benzimidazole (TCRB), J MED CHEM, 43(12), 2000, pp. 2449-2456
6-N-acyltriciribine analogues: Structure-activity relationship between acyl carbon chain length and activity against HIV-1
Authors: Porcari, AR Ptak, RG Borysko, KZ Breitenbach, JM Drach, JC Townsend, LB
Citation: Ar. Porcari et al., 6-N-acyltriciribine analogues: Structure-activity relationship between acyl carbon chain length and activity against HIV-1, J MED CHEM, 43(12), 2000, pp. 2457-2463
Synthesis and antiviral evaluation of halogenated beta-D- and -L-erythrofuranosylbenzimidazoles
Authors: Gudmundsson, KS Tidwell, J Lippa, N Koszalka, GW van Draanen, N Ptak, RG Drach, JC Townsend, LB
Citation: Ks. Gudmundsson et al., Synthesis and antiviral evaluation of halogenated beta-D- and -L-erythrofuranosylbenzimidazoles, J MED CHEM, 43(12), 2000, pp. 2464-2472
Synthesis of fluorosugar analogues of 2,5,6-trichloro-1-(beta-D-ribofuranosyl)benzimidazole as antivirals with potentially increased glycosidic bond stability
Authors: Gudmundsson, KS Freeman, GA Drach, JC Townsend, LB
Citation: Ks. Gudmundsson et al., Synthesis of fluorosugar analogues of 2,5,6-trichloro-1-(beta-D-ribofuranosyl)benzimidazole as antivirals with potentially increased glycosidic bond stability, J MED CHEM, 43(12), 2000, pp. 2473-2478
An unprecedented nitrogen elimination reaction: Mechanistic studies using N-15-labeled 4-amino-7-benzylpyrrolo[2,3-d][1,2,3]triazine-5-carbonitrile
Authors: Migawa, MT Townsend, LB
Citation: Mt. Migawa et Lb. Townsend, An unprecedented nitrogen elimination reaction: Mechanistic studies using N-15-labeled 4-amino-7-benzylpyrrolo[2,3-d][1,2,3]triazine-5-carbonitrile, ORG LETT, 1(4), 1999, pp. 537-539
Studies designed to increase the stability and antiviral activity (HCMV) of the active benzimidazole nucleoside, TCRB
Authors: Townsend, LB Gudmundsson, KS Daluge, SM Chen, JJ Zhu, ZJ Koszalka, GW Boyd, L Chamberlain, SD Freeman, GA Biron, KK Drach, JC
Citation: Lb. Townsend et al., Studies designed to increase the stability and antiviral activity (HCMV) of the active benzimidazole nucleoside, TCRB, NUCLEOS NUC, 18(4-5), 1999, pp. 509-519
Total synthesis of the naturally occurring antibiotic toyocamycin using new and improved synthetic procedures
Authors: Porcari, AR Townsend, LB
Citation: Ar. Porcari et Lb. Townsend, Total synthesis of the naturally occurring antibiotic toyocamycin using new and improved synthetic procedures, NUCLEOS NUC, 18(2), 1999, pp. 153-159
Analogs of AICA- and isoAICA ribosides and their methylated base counterparts.
Authors: Panzica, RP Townsend, LB
Citation: Rp. Panzica et Lb. Townsend, Analogs of AICA- and isoAICA ribosides and their methylated base counterparts., NUCLEOS NUC, 18(11-12), 1999, pp. 2345-2356
Acyclic sugar analogs of triciribine: Lack of antiviral and antiproliferative activity correlate with low intracellular phosphorylation
Authors: Porcari, AR Borysko, KZ Ptak, RG Breitenbach, JM Wotring, LL Drach, JC Townsend, LB
Citation: Ar. Porcari et al., Acyclic sugar analogs of triciribine: Lack of antiviral and antiproliferative activity correlate with low intracellular phosphorylation, NUCLEOS NUC, 18(11-12), 1999, pp. 2475-2497
Nonnucleoside pyrrolopyrimidines with a unique mechanism of action againsthuman cytomegalovirus
Authors: Jacobson, JG Renau, TE Nassiri, MR Sweier, DG Breitenbach, JM Townsend, LB Drach, JC
Citation: Jg. Jacobson et al., Nonnucleoside pyrrolopyrimidines with a unique mechanism of action againsthuman cytomegalovirus, ANTIM AG CH, 43(8), 1999, pp. 1888-1894
An efficient synthesis of 2-nitropyrrole-3,4-dicarboxamide
Authors: Migawa, MT Townsend, LB
Citation: Mt. Migawa et Lb. Townsend, An efficient synthesis of 2-nitropyrrole-3,4-dicarboxamide, SYN COMMUN, 29(21), 1999, pp. 3757-3772
Synthesis and regioselective ribosylation of 6,7-dichloroimidazo[4,5-b]quinolin-2-one
Authors: Zhu, ZJ Lippa, B Townsend, LB
Citation: Zj. Zhu et al., Synthesis and regioselective ribosylation of 6,7-dichloroimidazo[4,5-b]quinolin-2-one, J ORG CHEM, 64(11), 1999, pp. 4159-4168
Synthesis of beta-L-lyxofuranosyl benzimidazoles by an unexpected intramolecular displacement reaction
Authors: Girardet, JL Townsend, LB
Citation: Jl. Girardet et Lb. Townsend, Synthesis of beta-L-lyxofuranosyl benzimidazoles by an unexpected intramolecular displacement reaction, J ORG CHEM, 64(11), 1999, pp. 4169-4172
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