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Results: 1-20 |
Results: 20
Immucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytes
Authors: Kicska, GA Long, L Horig, H Fairchild, C Tyler, PC Furneaux, RH Schramm, VL Kaufman, HL
Citation: Ga. Kicska et al., Immucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytes, P NAS US, 98(8), 2001, pp. 4593-4598
Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine: Convergent synthesis of the aza-C-nucleoside immucillins
Authors: Evans, GB Furneaux, RH Hutchison, TL Kezar, HS Morris, PE Schramm, VL Tyler, PC
Citation: Gb. Evans et al., Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine: Convergent synthesis of the aza-C-nucleoside immucillins, J ORG CHEM, 66(17), 2001, pp. 5723-5730
Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis
Authors: Fedorov, A Shi, W Kicska, G Fedorov, E Tyler, PC Furneaux, RH Hanson, JC Gainsford, GJ Larese, JZ Schramm, VL Almo, SC
Citation: A. Fedorov et al., Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis, BIOCHEM, 40(4), 2001, pp. 853-860
Purine nucleoside phosphorylase from Mycobacterium tuberculosis. Analysis of inhibition by a transition-state analogue and dissection by parts
Authors: Basso, LA Santos, DS Shi, WX Furneaux, RH Tyler, PC Schramm, VL Blanchard, JS
Citation: La. Basso et al., Purine nucleoside phosphorylase from Mycobacterium tuberculosis. Analysis of inhibition by a transition-state analogue and dissection by parts, BIOCHEM, 40(28), 2001, pp. 8196-8203
Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces
Authors: Shi, WX Basso, LA Santos, DS Tyler, PC Furneaux, RH Blanchard, JS Almo, SC Schramm, VL
Citation: Wx. Shi et al., Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces, BIOCHEM, 40(28), 2001, pp. 8204-8215
Ricin A-chain inhibitors resembling the oxacarbenium ion transition state
Authors: Tanaka, KSE Chen, XY Ishikawa, Y Tyler, PC Furneaux, RH Schramm, VL
Citation: Kse. Tanaka et al., Ricin A-chain inhibitors resembling the oxacarbenium ion transition state, BIOCHEM, 40(23), 2001, pp. 6845-6851
Stereoselective total synthesis of (+/-)-thielocin Al beta
Authors: Genisson, Y Tyler, PC Ball, RG Young, RN
Citation: Y. Genisson et al., Stereoselective total synthesis of (+/-)-thielocin Al beta, J AM CHEM S, 123(46), 2001, pp. 11381-11387
1,7,8-tri-O-acetyl-6-O-benzoyl-castanospermine
Authors: Gainsford, GJ Tyler, PC Furneaux, RH
Citation: Gj. Gainsford et al., 1,7,8-tri-O-acetyl-6-O-benzoyl-castanospermine, ACT CRYST C, 56, 2000, pp. E394-E395
1,2,7,8-Tetra-O-acetylaustraline
Authors: Gainsford, GJ Furneaux, RH Mason, JM Tyler, PC
Citation: Gj. Gainsford et al., 1,2,7,8-Tetra-O-acetylaustraline, ACT CRYST C, 56, 2000, pp. E477-E478
Synthesis of transition state analogue inhibitors for purine nucleoside phosphorylase and N-riboside hydrolases
Authors: Evans, GB Furneaux, RH Gainsford, GJ Schramm, VL Tyler, PC
Citation: Gb. Evans et al., Synthesis of transition state analogue inhibitors for purine nucleoside phosphorylase and N-riboside hydrolases, TETRAHEDRON, 56(19), 2000, pp. 3053-3062
New syntheses of 1D-and 1L-1,2-anhydromo-myo-inositol and assessment of their glycosidase inhibitory activities
Authors: Falshaw, A Hart, JB Tyler, PC
Citation: A. Falshaw et al., New syntheses of 1D-and 1L-1,2-anhydromo-myo-inositol and assessment of their glycosidase inhibitory activities, CARBOHY RES, 329(2), 2000, pp. 301-308
Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at1.75 angstrom
Authors: Shi, WX Munagala, NR Wang, CC Li, CM Tyler, PC Furneaux, RH Grubmeyer, C Schramm, VL Almo, SC
Citation: Wx. Shi et al., Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at1.75 angstrom, BIOCHEM, 39(23), 2000, pp. 6781-6790
Transition-state analogs as inhibitors of human and malarial hypoxanthine-guanine phosphoribosyltransferases
Authors: Li, CM Tyler, PC Furneaux, RH Kicska, G Xu, YM Grubmeyer, C Girvin, ME Schramm, VL
Citation: Cm. Li et al., Transition-state analogs as inhibitors of human and malarial hypoxanthine-guanine phosphoribosyltransferases, NAT ST BIOL, 6(6), 1999, pp. 582-587
The 2.0 angstrom structure of human hypoxanthineguanine phosphoribosyltransferase in complex with a transition-state analog inhibitor
Authors: Shi, WX Li, CM Tyler, PC Furneaux, RH Grubmeyer, C Schramm, VL Almo, SC
Citation: Wx. Shi et al., The 2.0 angstrom structure of human hypoxanthineguanine phosphoribosyltransferase in complex with a transition-state analog inhibitor, NAT ST BIOL, 6(6), 1999, pp. 588-593
Prostaglandin E-2-bisphosphonate conjugates: Potential agents for treatment of osteoporosis
Authors: Gil, L Han, YX Opas, EE Rodan, GA Ruel, R Seedor, JG Tyler, PC Young, RN
Citation: L. Gil et al., Prostaglandin E-2-bisphosphonate conjugates: Potential agents for treatment of osteoporosis, BIO MED CH, 7(5), 1999, pp. 901-919
Transition state analogue inhibitors of protozoan nucleoside hydrolases
Authors: Furneaux, RH Schramm, VL Tyler, PC
Citation: Rh. Furneaux et al., Transition state analogue inhibitors of protozoan nucleoside hydrolases, BIO MED CH, 7(11), 1999, pp. 2599-2606
Development of a tetrazolium salt assay for rapid determination of viability of BCG vaccines
Authors: Kairo, SK Bedwell, J Tyler, PC Carter, A Corbel, MJ
Citation: Sk. Kairo et al., Development of a tetrazolium salt assay for rapid determination of viability of BCG vaccines, VACCINE, 17(19), 1999, pp. 2423-2428
Improved syntheses of 3H,5H-pyrrolo[3,2-d]pyrimidines
Authors: Furneaux, RH Tyler, PC
Citation: Rh. Furneaux et Pc. Tyler, Improved syntheses of 3H,5H-pyrrolo[3,2-d]pyrimidines, J ORG CHEM, 64(22), 1999, pp. 8411-8412
Iminoribitol transition state analogue inhibitors of protozoan nucleoside hydrolases
Authors: Miles, RW Tyler, PC Evans, GB Furneaux, RH Parkin, DW Schramm, VL
Citation: Rw. Miles et al., Iminoribitol transition state analogue inhibitors of protozoan nucleoside hydrolases, BIOCHEM, 38(40), 1999, pp. 13147-13154
The 2.0 angstrom structure of malarial purine phosphoribosyltransferase incomplex with a transition-state analogue inhibitor
Authors: Shi, WX Li, CM Tyler, PC Furneaux, RH Cahill, SM Girvin, ME Grubmeyer, C Schramm, VL Almo, SC
Citation: Wx. Shi et al., The 2.0 angstrom structure of malarial purine phosphoribosyltransferase incomplex with a transition-state analogue inhibitor, BIOCHEM, 38(31), 1999, pp. 9872-9880
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