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Results: 101-125/154
High-level expression and purification of biologically active recombinant pokeweed antiviral protein
Authors:
Rajamohan, F
Engstrom, CR
Denton, TJ
Engen, LA
Kourinov, I
Uckun, FM
Citation: F. Rajamohan et al., High-level expression and purification of biologically active recombinant pokeweed antiviral protein, PROT EX PUR, 16(2), 1999, pp. 359-368
Authors:
Messinger, Y
Uckun, FM
Citation: Y. Messinger et Fm. Uckun, A critical risk-benefit assessment argues against the use of anthracyclines in induction regimens for newly diagnosed childhood acute lymphoblastic leukemia, LEUK LYMPH, 34(5-6), 1999, pp. 415-432
Authors:
Messinger, Y
Reaman, GH
Ek, O
Uckun, FM
Citation: Y. Messinger et al., Evaluation of temozolomide in a SCID mouse model of human B-cell precursorleukemia, LEUK LYMPH, 33(3-4), 1999, pp. 289-293
Authors:
Uckun, FM
Nachman, JB
Sather, HN
Sensel, MG
Kraft, P
Steinherz, PG
Lange, B
Hutchinson, R
Reaman, GH
Gaynon, PS
Heerema, NA
Citation: Fm. Uckun et al., Poor treatment outcome of Philadelphia chromosome-positive pediatric acutelymphoblastic leukemia despite intensive chemotherapy, LEUK LYMPH, 33(1-2), 1999, pp. 101-106
Authors:
Uckun, FM
Waurzyniak, BJ
Sather, HN
Sensel, MG
Chelstrom, L
Nachman, J
Gaynon, PS
Bostrom, B
Ek, O
Sarquis, M
Steinherz, PG
Reaman, GH
Citation: Fm. Uckun et al., Prognostic significance of T-lineage leukemic cell growth in SCID mice: A children's cancer group study, LEUK LYMPH, 32(5-6), 1999, pp. 475
Authors:
Witthuhn, BA
Williams, MD
Kerawalla, H
Uckun, FM
Citation: Ba. Witthuhn et al., Differential substrate recognition capabilities of Janus family protein tyrosine kinases within the interleukin 2 receptor (Il2R) system: Jak3 as a potential molecular target for treatment of leukemias with a hyperactive Jak-STAT signaling machinery, LEUK LYMPH, 32(3-4), 1999, pp. 289-297
Authors:
Kurinov, IV
Myers, DE
Irvin, JD
Uckun, FM
Citation: Iv. Kurinov et al., X-ray crystallographic analysis of the structural basis for the interactions of pokeweed antiviral protein with its active site inhibitor and ribosomal RNA substrate analogs, PROTEIN SCI, 8(9), 1999, pp. 1765-1772
Authors:
Kurinov, IV
Rajamohan, F
Venkatachalam, TK
Uckun, FM
Citation: Iv. Kurinov et al., X-ray crystallographic analysis of the structural basis for the interaction of pokeweed antiviral protein with guanine residues of ribosomal RNA, PROTEIN SCI, 8(11), 1999, pp. 2399-2405
Authors:
Uckun, FM
Pendergrass, S
Maher, D
Zhu, D
Tuel-Ahlgren, L
Mao, C
Venkatachalam, TK
Citation: Fm. Uckun et al., N '-[2-(2-thiophene)ethyl]-N '-[2-(5-bromopyridyl)] thiourea as a potent inhibitor of NNI-resistant and multidrug-resistant human immunodeficiency virus-1, BIOORG MED, 9(24), 1999, pp. 3411-3416
Authors:
Uckun, FM
Mao, C
Pendergrass, S
Maher, D
Zhu, D
Tuel-Ahlgren, L
Venkatachalam, TK
Citation: Fm. Uckun et al., N-[2-(1-cyclohexenyl)ethyl]-N '-[2-(5-bromopyridyl)]-thiourea and N '-[2-(1-cyclohexenyl)ethyl]-N '-[2-(5-chloropyridyl)]- thiourea as potent inhibitors of multidrug-resistant human immunodeficiency virus-1, BIOORG MED, 9(18), 1999, pp. 2721-2726
Authors:
Mao, C
Sudbeck, EA
Venkatachalam, TK
Uckun, FM
Citation: C. Mao et al., Rational design of N-[2-(2,5-dimethoxyphenylethyl)]-N '-[2-(5-bromopyridyl)]-thiourea (HI-236) as a potent non-nucleoside inhibitor of drug-resistanthuman immunodeficiency virus, BIOORG MED, 9(11), 1999, pp. 1593-1598
Authors:
Mao, C
Sudbeck, EA
Venkatachalam, TK
Uckun, FM
Citation: C. Mao et al., Structure-based design of non-nucleoside reverse transcriptase inhibitors of drug-resistant human immunodeficiency virus, ANTIVIR CHE, 10(5), 1999, pp. 233-240
Authors:
Jan, ST
Shih, MJ
Venkatachalam, TK
D'Cruz, OJ
Chen, CL
Uckun, FM
Citation: St. Jan et al., Synthesis of dual function (5R,6R)- and (5S,6S)-5-bromo-6-methoxy-5,6-dihydro-AZT-5 '-(para-bromophenyl methoxyalaninyl phosphate) as novel spermicidal and anti-HIV agents, ANTIVIR CHE, 10(1), 1999, pp. 39-46
Authors:
Jan, ST
Zhu, Z
Tai, HL
Shih, MJ
Venkatachalam, TK
Uckun, FM
Citation: St. Jan et al., AZT-5 '-(p-bromophenyl methoxyalaninyl phosphate) as a potent and non-toxic anti-human immunodeficiency virus agent, ANTIVIR CHE, 10(1), 1999, pp. 47-52
Authors:
Reaman, GH
Sposto, R
Sensel, MG
Lange, BJ
Feusner, JH
Heerema, NA
Leonard, M
Holmes, EJ
Sather, HN
Pendergrass, TW
Johnstone, HS
O'Brien, RT
Steinherz, PG
Zeltzer, PM
Gaynon, PS
Trigg, ME
Uckun, FM
Citation: Gh. Reaman et al., Treatment outcome and prognostic factors for infants with acute lymphoblastic leukemia treated on two consecutive trials of the Children's Cancer Group, J CL ONCOL, 17(2), 1999, pp. 445-455
Expression of aberrantly spliced oncogenic Ikaros isoforms in childhood acute lymphoblastic leukemia
Authors:
Sun, L
Goodman, PA
Wood, CM
Crotty, ML
Sensel, M
Sather, H
Navara, C
Nachman, J
Steinherz, PG
Gaynon, PS
Seibel, N
Vassilev, A
Juran, BD
Reaman, GH
Uckun, FM
Citation: L. Sun et al., Expression of aberrantly spliced oncogenic Ikaros isoforms in childhood acute lymphoblastic leukemia, J CL ONCOL, 17(12), 1999, pp. 3753-3766
Authors:
Chen, CL
Uckun, FM
Citation: Cl. Chen et Fm. Uckun, Evaluation of the pharmacokinetic features and tissue distribution of the potent nonnucleoside inhibitor of HIV-1 reverse transcriptase, N-[2-(2-fluorophenethyl)]-N '-[2-(5-bromopyridyl)]-thiourea (HI-240) with an analyticalHPLC method, PHARM RES, 16(8), 1999, pp. 1226-1232
Authors:
Chen, CL
Tai, HL
Zhu, DM
Uckun, FM
Citation: Cl. Chen et al., Pharmacokinetic features and metabolism of calphostin C, a naturally occurring perylenequinone with antileukemic activity, PHARM RES, 16(7), 1999, pp. 1003-1009
Authors:
Chen, CL
Malaviya, R
Navara, C
Chen, H
Bechard, B
Mitcheltree, G
Liu, XP
Uckun, FM
Citation: Cl. Chen et al., Pharmacokinetics and biologic activity of the novel mast cell inhibitor, 4-(3 '-hydroxyphenyl)amino-6,7-dimethoxyquinazoline in mice, PHARM RES, 16(1), 1999, pp. 117-122
Authors:
Ghosh, S
Narla, RK
Zheng, YG
Liu, XP
Jun, X
Mao, C
Sudbeck, EA
Uckun, FM
Citation: S. Ghosh et al., Structure-based design of potent inhibitors of EGF-receptor tyrosine kinase as anti-cancer agents, ANTI-CAN DR, 14(5), 1999, pp. 403-410
Authors:
Ghosh, P
D'Cruz, OJ
DuMez, DD
Peitersen, J
Uckun, FM
Citation: P. Ghosh et al., Structural and functional characterization of seven spermicidal vanadium(IV) complexes: potentiation of activity by methyl substitution on the cyclopentadienyl rings, J INORG BIO, 75(2), 1999, pp. 135-143
Authors:
Ghosh, S
Uckun, FM
Citation: S. Ghosh et Fm. Uckun, alpha-cyano-N-(2,5-dibromophenyl)-beta-hydroxybut-2-enamide, ACT CRYST C, 55, 1999, pp. 1364-1365
Authors:
Ghosh, S
Zheng, YG
Uckun, FM
Citation: S. Ghosh et al., Five analogs of the active metabolite of leflunomide, ACT CRYST C, 55, 1999, pp. 2117-2122
Authors:
Chen, CL
Levine, A
Rao, A
O'Neill, K
Messinger, Y
Myers, DE
Goldman, F
Hurvitz, C
Casper, JT
Uckun, FM
Citation: Cl. Chen et al., Clinical pharmacokinetics of the CD19 receptor-directed tyrosine kinase inhibitor B43-Genistein in patients with B-lineage lymphoid malignancies, J CLIN PHAR, 39(12), 1999, pp. 1248-1255
Authors:
Aubrecht, J
Narla, RK
Ghosh, P
Stanek, J
Uckun, FM
Citation: J. Aubrecht et al., Molecular genotoxicity profiles of apoptosis-inducing vanadocene complexes, TOX APPL PH, 154(3), 1999, pp. 228-235