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Results: 1-25 | 26-39
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SYNTHESIS AND PROPERTIES OF PRODRUGS ACTIVATED IN HYPOXIA TO GIVE BLEOMYCIN ANALOGS
Authors: HIGHFIELD JA MEHTA LK PARRICK J CANDEIAS LP WARDMAN P
Citation: Ja. Highfield et al., SYNTHESIS AND PROPERTIES OF PRODRUGS ACTIVATED IN HYPOXIA TO GIVE BLEOMYCIN ANALOGS, Bioorganic & medicinal chemistry letters, 8(18), 1998, pp. 2609-2614
RATIONAL DESIGN OF NOVEL BIOREDUCTIVELY-ACTIVATED PRODRUGS FOR THE TARGETED DELIVERY OF EFFECTOR MOLECULES TO TUMORS
Authors: EVERETT SA HUDNOTT AR MOODY CJ NAYLOR MA NOLAN J PATEL KB STRATFORD MRL SWANN E WARDMAN P
Citation: Sa. Everett et al., RATIONAL DESIGN OF NOVEL BIOREDUCTIVELY-ACTIVATED PRODRUGS FOR THE TARGETED DELIVERY OF EFFECTOR MOLECULES TO TUMORS, Annals of oncology, 9, 1998, pp. 111-111
REACTIVITY OF NITROGEN-DIOXIDE TOWARDS HYDROPHILIC ANTIOXIDANTS - THERADICAL SINK
Authors: WARDMAN P ATSIPAPA E HUGHES MN
Citation: P. Wardman et al., REACTIVITY OF NITROGEN-DIOXIDE TOWARDS HYDROPHILIC ANTIOXIDANTS - THERADICAL SINK, Free radical biology & medicine, 25, 1998, pp. 6-6
OXIDATIVE DENITRIFICATION OF THE ANTITUMOR DRUG HYDROXYGUANIDINE
Authors: EVERETT SA PATEL KB DENNIS MF SMITH KA STRATFORD MRL WARDMAN P
Citation: Sa. Everett et al., OXIDATIVE DENITRIFICATION OF THE ANTITUMOR DRUG HYDROXYGUANIDINE, Free radical biology & medicine, 24(1), 1998, pp. 1-10
TOWARD TARGETED OXIDATION THERAPY OF CANCER - PEROXIDASE-CATALYZED CYTOTOXICITY OF INDOLE-3-ACETIC ACIDS
Authors: FOLKES LK CANDEIAS LP WARDMAN P
Citation: Lk. Folkes et al., TOWARD TARGETED OXIDATION THERAPY OF CANCER - PEROXIDASE-CATALYZED CYTOTOXICITY OF INDOLE-3-ACETIC ACIDS, International journal of radiation oncology, biology, physics, 42(4), 1998, pp. 917-920
EVALUATION OF THE RADICAL SINK HYPOTHESIS FROM A CHEMICAL-KINETIC VIEWPOINT
Authors: WARDMAN P
Citation: P. Wardman, EVALUATION OF THE RADICAL SINK HYPOTHESIS FROM A CHEMICAL-KINETIC VIEWPOINT, Journal of radioanalytical and nuclear chemistry, 232(1-2), 1998, pp. 23-27
INDOLEQUINONE ANTITUMOR AGENTS - REDUCTIVE ACTIVATION AND ELIMINATIONFROM (5-METHOXY-1-METHYL-4,7-DIOXOINDOL-3-YL)METHYL DERIVATIVES AND HYPOXIA-SELECTIVE CYTOTOXICITY IN-VITRO
Authors: NAYLOR MA SWANN E EVERETT SA JAFFAR M NOLAN J ROBERTSON N LOCKYER SD PATEL KB DENNIS MF STRATFORD MRL WARDMAN P ADAMS GE MOODY CJ STRATFORD IJ
Citation: Ma. Naylor et al., INDOLEQUINONE ANTITUMOR AGENTS - REDUCTIVE ACTIVATION AND ELIMINATIONFROM (5-METHOXY-1-METHYL-4,7-DIOXOINDOL-3-YL)METHYL DERIVATIVES AND HYPOXIA-SELECTIVE CYTOTOXICITY IN-VITRO, Journal of medicinal chemistry, 41(15), 1998, pp. 2720-2731
HIGH-PERFORMANCE ION CHROMATOGRAPHY APPLIED TO FREE-RADICAL MECHANISMS IN DRUG DESIGN - THE PROBLEM OF ION ANALYSIS AT HIGH IONIC STRENGTHS
Authors: EVERETT SA DENNIS MF PATEL KB WARDMAN P STRATFORD MRL
Citation: Sa. Everett et al., HIGH-PERFORMANCE ION CHROMATOGRAPHY APPLIED TO FREE-RADICAL MECHANISMS IN DRUG DESIGN - THE PROBLEM OF ION ANALYSIS AT HIGH IONIC STRENGTHS, Journal of chromatography, 770(1-2), 1997, pp. 273-279
THE REACTION OF OXYGEN WITH RADICALS FROM OXIDATION OF TRYPTOPHAN ANDINDOLE-3-ACETIC-ACID
Authors: CANDEIAS LP WARDMAN P MASON RP
Citation: Lp. Candeias et al., THE REACTION OF OXYGEN WITH RADICALS FROM OXIDATION OF TRYPTOPHAN ANDINDOLE-3-ACETIC-ACID, Biophysical chemistry, 67(1-3), 1997, pp. 229-237
RATES OF DECARBOXYLATION OF THE RADICAL CATIONS OF INDOL-3-YLACETIC ACIDS AND COMPARISON WITH INDOLIZIN-1-YLACETIC ACIDS
Authors: MEHTA LK PORSSA M PARRICK J CANDEIAS LP WARDMAN P
Citation: Lk. Mehta et al., RATES OF DECARBOXYLATION OF THE RADICAL CATIONS OF INDOL-3-YLACETIC ACIDS AND COMPARISON WITH INDOLIZIN-1-YLACETIC ACIDS, Perkin transactions. 2, (8), 1997, pp. 1487-1491
MEASUREMENT OF TUMOR OXYGENATION - A COMPARISON BETWEEN POLAROGRAPHICNEEDLE ELECTRODES AND A TIME-RESOLVED LUMINESCENCE-BASED OPTICAL SENSOR
Authors: COLLINGRIDGE DR YOUNG WK VOJNOVIC B WARDMAN P LYNCH EM HILL SA CHAPLIN DJ
Citation: Dr. Collingridge et al., MEASUREMENT OF TUMOR OXYGENATION - A COMPARISON BETWEEN POLAROGRAPHICNEEDLE ELECTRODES AND A TIME-RESOLVED LUMINESCENCE-BASED OPTICAL SENSOR, Radiation research, 147(3), 1997, pp. 329-334
HYPOXIA-SELECTIVE ANTITUMOR AGENTS .15. MODIFICATION OF RATE OF NITROREDUCTION AND EXTENT OF LYSOSOMAL UPTAKE BY POLYSUBSTITUTION OF 4-(ALKYLAMINO)-5-NITROQUINOLINE BIOREDUCTIVE DRUGS
Authors: SIIM BG ATWELL GJ ANDERSON RF WARDMAN P PULLEN SM WILSON WR DENNY WA
Citation: Bg. Siim et al., HYPOXIA-SELECTIVE ANTITUMOR AGENTS .15. MODIFICATION OF RATE OF NITROREDUCTION AND EXTENT OF LYSOSOMAL UPTAKE BY POLYSUBSTITUTION OF 4-(ALKYLAMINO)-5-NITROQUINOLINE BIOREDUCTIVE DRUGS, Journal of medicinal chemistry, 40(9), 1997, pp. 1381-1390
FACTORS CONTROLLING THE SUBSTRATE-SPECIFICITY OF PEROXIDASES - KINETICS AND THERMODYNAMICS OF THE REACTION OF HORSERADISH-PEROXIDASE COMPOUND-I WITH PHENOLS AND INDOLE-3-ACETIC ACIDS
Authors: CANDEIAS LP FOLKES LK WARDMAN P
Citation: Lp. Candeias et al., FACTORS CONTROLLING THE SUBSTRATE-SPECIFICITY OF PEROXIDASES - KINETICS AND THERMODYNAMICS OF THE REACTION OF HORSERADISH-PEROXIDASE COMPOUND-I WITH PHENOLS AND INDOLE-3-ACETIC ACIDS, Biochemistry, 36(23), 1997, pp. 7081-7085
ENHANCEMENT OF PEROXIDASE-INDUCED LIPID-PEROXIDATION BY INDOLE-3-ACETIC-ACID - EFFECT OF ANTIOXIDANTS
Authors: CANDEIAS LP FOLKES LK WARDMAN P
Citation: Lp. Candeias et al., ENHANCEMENT OF PEROXIDASE-INDUCED LIPID-PEROXIDATION BY INDOLE-3-ACETIC-ACID - EFFECT OF ANTIOXIDANTS, Redox report, 2(2), 1996, pp. 141-147
THE ONE-ELECTRON REDUCTION POTENTIAL OF 3-AMINO-1,2,4-BENZOTRIAZINE 1,4-DIOXIDE (TIRAPAZAMINE) - A HYPOXIA-SELECTIVE BIOREDUCTIVE DRUG
Authors: PRIYADARSINI KI TRACY M WARDMAN P
Citation: Ki. Priyadarsini et al., THE ONE-ELECTRON REDUCTION POTENTIAL OF 3-AMINO-1,2,4-BENZOTRIAZINE 1,4-DIOXIDE (TIRAPAZAMINE) - A HYPOXIA-SELECTIVE BIOREDUCTIVE DRUG, Free radical research, 25(5), 1996, pp. 393-399
ELECTRON-TRANSFER REACTIONS IN RB90745, A BIOREDUCTIVE DRUG HAVING BOTH AROMATIC N-OXIDE AND NITROARENE MOIETIES
Authors: PRIYADARSINI KI NAYLOR MA STRATFORD MRL WARDMAN P
Citation: Ki. Priyadarsini et al., ELECTRON-TRANSFER REACTIONS IN RB90745, A BIOREDUCTIVE DRUG HAVING BOTH AROMATIC N-OXIDE AND NITROARENE MOIETIES, Free radical research, 25(2), 1996, pp. 99-107
OXIDATIVE DENITRIFICATION OF N-OMEGA-HYDROXY-L-ARGININE BY THE SUPEROXIDE RADICAL-ANION
Authors: EVERETT SA DENNIS MF PATEL KB STRATFORD MRL WARDMAN P
Citation: Sa. Everett et al., OXIDATIVE DENITRIFICATION OF N-OMEGA-HYDROXY-L-ARGININE BY THE SUPEROXIDE RADICAL-ANION, Biochemical journal, 317, 1996, pp. 17-21
FENTON CHEMISTRY - AN INTRODUCTION
Authors: WARDMAN P CANDEIAS LP
Citation: P. Wardman et Lp. Candeias, FENTON CHEMISTRY - AN INTRODUCTION, Radiation research, 145(5), 1996, pp. 523-531
CHEMICAL-PROPERTIES WHICH CONTROL SELECTIVITY AND EFFICACY OF AROMATIC N-OXIDE BIOREDUCTIVE DRUGS
Authors: WARDMAN P PRIYADARSINI KI DENNIS MF EVERETT SA NAYLOR MA PATEL KB STRATFORD IJ STRATFORD MRL TRACY M
Citation: P. Wardman et al., CHEMICAL-PROPERTIES WHICH CONTROL SELECTIVITY AND EFFICACY OF AROMATIC N-OXIDE BIOREDUCTIVE DRUGS, British Journal of Cancer, 74, 1996, pp. 70-74
NITRIC-OXIDE INVOLVEMENT IN THE TOXICITY OF HYDROXYGUANIDINE IN LEUKEMIA HL-60 CELLS
Authors: EVERETT SA SMITH KA PATEL KB DENNIS MF STRATFORD MRL WARDMAN P
Citation: Sa. Everett et al., NITRIC-OXIDE INVOLVEMENT IN THE TOXICITY OF HYDROXYGUANIDINE IN LEUKEMIA HL-60 CELLS, British Journal of Cancer, 74, 1996, pp. 172-176
MEASUREMENT OF OXYGEN-TENSION IN TUMORS BY TIME-RESOLVED FLUORESCENCE
Authors: YOUNG WK VOJNOVIC B WARDMAN P
Citation: Wk. Young et al., MEASUREMENT OF OXYGEN-TENSION IN TUMORS BY TIME-RESOLVED FLUORESCENCE, British Journal of Cancer, 74, 1996, pp. 256-259
RATES OF REACTION OF INDOLEACETIC ACIDS WITH HORSERADISH-PEROXIDASE COMPOUND-I AND THEIR DEPENDENCE ON THE REDOX POTENTIALS
Authors: CANDEIAS LP FOLKES LK PORSSA M PARRICK J WARDMAN P
Citation: Lp. Candeias et al., RATES OF REACTION OF INDOLEACETIC ACIDS WITH HORSERADISH-PEROXIDASE COMPOUND-I AND THEIR DEPENDENCE ON THE REDOX POTENTIALS, Biochemistry, 35(1), 1996, pp. 102-108
FREE-RADICAL INTERMEDIATES IN THE REDUCTION OF QUINOXALINE N-OXIDE ANTITUMOR DRUGS - REDOX AND PROTOTROPIC REACTIONS
Authors: PRIYADARSINI KI DENNIS MF NAYLOR MA STRATFORD MRL WARDMAN P
Citation: Ki. Priyadarsini et al., FREE-RADICAL INTERMEDIATES IN THE REDUCTION OF QUINOXALINE N-OXIDE ANTITUMOR DRUGS - REDOX AND PROTOTROPIC REACTIONS, Journal of the American Chemical Society, 118(24), 1996, pp. 5648-5654
NITRIC-OXIDE IN BIOLOGICAL-FLUIDS - ANALYSIS OF NITRITE AND NITRATE BY HIGH-PERFORMANCE ION CHROMATOGRAPHY
Authors: EVERETT SA DENNIS MF TOZER GM PRISE VE WARDMAN P STRATFORD MRL
Citation: Sa. Everett et al., NITRIC-OXIDE IN BIOLOGICAL-FLUIDS - ANALYSIS OF NITRITE AND NITRATE BY HIGH-PERFORMANCE ION CHROMATOGRAPHY, Journal of chromatography, 706(1-2), 1995, pp. 437-442
ENHANCEMENT OF LIPID-PEROXIDATION BY INDOLE-3-ACETIC-ACID AND DERIVATIVES - SUBSTITUENT EFFECTS
Authors: CANDEIAS LP FOLKES LK PORSSA M PARRICK J WARDMAN P
Citation: Lp. Candeias et al., ENHANCEMENT OF LIPID-PEROXIDATION BY INDOLE-3-ACETIC-ACID AND DERIVATIVES - SUBSTITUENT EFFECTS, Free radical research, 23(5), 1995, pp. 403-418
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