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Results: 1-25 | 26-28
Results: 1-25/28
THE NUCLEAR RECEPTOR PPAR-GAMMA - BIGGER THAN FAT
Authors: KLIEWER SA WILLSON TM
Citation: Sa. Kliewer et Tm. Willson, THE NUCLEAR RECEPTOR PPAR-GAMMA - BIGGER THAN FAT, Current opinion in genetics & development, 8(5), 1998, pp. 576-581
AN ORPHAN NUCLEAR RECEPTOR-ACTIVATED BY PREGNANES DEFINES A NOVEL STEROID SIGNALING PATHWAY
Authors: KLIEWER SA MOORE JT WADE L STAUDINGER JL WATSON MA JONES SA MCKEE DD OLIVER BB WILLSON TM ZETTERSTROM RH PERLMANN T LEHMANN JM
Citation: Sa. Kliewer et al., AN ORPHAN NUCLEAR RECEPTOR-ACTIVATED BY PREGNANES DEFINES A NOVEL STEROID SIGNALING PATHWAY, Cell, 92(1), 1998, pp. 73-82
LIGAND-BINDING AND COACTIVATOR ASSEMBLY OF THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA
Authors: NOLTE RT WISELY GB WESTIN S COBB JE LAMBERT MH KUROKAWA R ROSENFELD MG WILLSON TM GLASS CK MILBURN MV
Citation: Rt. Nolte et al., LIGAND-BINDING AND COACTIVATOR ASSEMBLY OF THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA, Nature, 395(6698), 1998, pp. 137-143
THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA IS A NEGATIVE REGULATOR OF MACROPHAGE ACTIVATION
Authors: RICOTE M LI AC WILLSON TM KELLY CJ GLASS CK
Citation: M. Ricote et al., THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA IS A NEGATIVE REGULATOR OF MACROPHAGE ACTIVATION, Nature, 391(6662), 1998, pp. 79-82
THE HUMAN ORPHAN NUCLEAR RECEPTOR PXR IS ACTIVATED BY COMPOUNDS THAT REGULATE CYP3A4 GENE-EXPRESSION AND CAUSE DRUG-INTERACTIONS
Authors: LEHMANN JM MCKEE DD WATSON MA WILLSON TM MOORE JT KLIEWER SA
Citation: Jm. Lehmann et al., THE HUMAN ORPHAN NUCLEAR RECEPTOR PXR IS ACTIVATED BY COMPOUNDS THAT REGULATE CYP3A4 GENE-EXPRESSION AND CAUSE DRUG-INTERACTIONS, The Journal of clinical investigation, 102(5), 1998, pp. 1016-1023
CLONING AND CHARACTERIZATION OF HUMAN ESTROGEN-RECEPTOR BETA-ISOFORMS
Authors: MOORE JT MCKEE DD SLENTZKESLER K MOORE LB JONES SA HORNE EL SU JL KLIEWER SA LEHMANN JM WILLSON TM
Citation: Jt. Moore et al., CLONING AND CHARACTERIZATION OF HUMAN ESTROGEN-RECEPTOR BETA-ISOFORMS, Biochemical and biophysical research communications, 247(1), 1998, pp. 75-78
PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONISTS
Authors: WILLSON TM WAHLI W
Citation: Tm. Willson et W. Wahli, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONISTS, CURRENT OPINION IN CHEMICAL BIOLOGY, 1(2), 1997, pp. 235-241
IDENTIFICATION OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR LIGANDS FROM A BIASED CHEMICAL LIBRARY
Authors: BROWN PJ SMITHOLIVER TA CHARIFSON PS TOMKINSON NCO FIVUSH AM STERNBACH DD WADE LE ORBANDMILLER L PARKS DJ BLANCHARD SG KLIEWER SA LEHMANN JM WILLSON TM
Citation: Pj. Brown et al., IDENTIFICATION OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR LIGANDS FROM A BIASED CHEMICAL LIBRARY, Chemistry & biology, 4(12), 1997, pp. 909-918
CONVERSION OF ACYCLIC NONPEPTIDE CCK ANTAGONISTS INTO CCK AGONISTS
Authors: HIRST GC QUEEN KL SUGG EE WILLSON TM
Citation: Gc. Hirst et al., CONVERSION OF ACYCLIC NONPEPTIDE CCK ANTAGONISTS INTO CCK AGONISTS, Bioorganic & medicinal chemistry letters, 7(5), 1997, pp. 511-514
SOLID-PHASE SYNTHESIS OF HYBRID THIAZOLIDINEDIONE-FATTY ACID PPAR-GAMMA LIGANDS
Authors: TOMKINSON NCO SEFLER AM PLUNKET KD BLANCHARD SG PARKS DJ WILLSON TM
Citation: Nco. Tomkinson et al., SOLID-PHASE SYNTHESIS OF HYBRID THIAZOLIDINEDIONE-FATTY ACID PPAR-GAMMA LIGANDS, Bioorganic & medicinal chemistry letters, 7(19), 1997, pp. 2491-2496
PROBING THE STRUCTURE AND FUNCTION OF THE ESTROGEN-RECEPTOR LIGAND-BINDING DOMAIN BY ANALYSIS OF MUTANTS WITH ALTERED TRANSACTIVATION CHARACTERISTICS
Authors: ENG FCS LEE HS FERRARA J WILLSON TM WHITE JH
Citation: Fcs. Eng et al., PROBING THE STRUCTURE AND FUNCTION OF THE ESTROGEN-RECEPTOR LIGAND-BINDING DOMAIN BY ANALYSIS OF MUTANTS WITH ALTERED TRANSACTIVATION CHARACTERISTICS, Molecular and cellular biology, 17(8), 1997, pp. 4644-4653
AMEBA - AN ACID-SENSITIVE ALDEHYDE RESIN FOR SOLID-PHASE SYNTHESIS
Authors: FIVUSH AM WILLSON TM
Citation: Am. Fivush et Tm. Willson, AMEBA - AN ACID-SENSITIVE ALDEHYDE RESIN FOR SOLID-PHASE SYNTHESIS, Tetrahedron letters, 38(41), 1997, pp. 7151-7154
GENERATION OF SECONDARY ALKYL AMINES ON SOLID SUPPORT BY BORANE REDUCTION - APPLICATION TO THE PARALLEL SYNTHESIS OF PPAR LIGANDS
Authors: BROWN PJ HURLEY KP STUART LW WILLSON TM
Citation: Pj. Brown et al., GENERATION OF SECONDARY ALKYL AMINES ON SOLID SUPPORT BY BORANE REDUCTION - APPLICATION TO THE PARALLEL SYNTHESIS OF PPAR LIGANDS, Synthesis, (7), 1997, pp. 778
FATTY-ACIDS AND EICOSANOIDS REGULATE GENE-EXPRESSION THROUGH DIRECT INTERACTIONS WITH PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-ALPHA AND RECEPTOR-GAMMA
Authors: KLIEWER SA SUNDSETH SS JONES SA BROWN PJ WISELY GB KOBLE CS DEVCHAND P WAHLI W WILLSON TM LENHARD JM LEHMANN JM
Citation: Sa. Kliewer et al., FATTY-ACIDS AND EICOSANOIDS REGULATE GENE-EXPRESSION THROUGH DIRECT INTERACTIONS WITH PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-ALPHA AND RECEPTOR-GAMMA, Proceedings of the National Academy of Sciences of the United Statesof America, 94(9), 1997, pp. 4318-4323
ACTIVATION OF THE ORPHAN RECEPTOR RIP14 BY RETINOIDS
Authors: ZAVACKI AM LEHMANN JM SEOL W WILLSON TM KLIEWER SA MOORE DD
Citation: Am. Zavacki et al., ACTIVATION OF THE ORPHAN RECEPTOR RIP14 BY RETINOIDS, Proceedings of the National Academy of Sciences of the United Statesof America, 94(15), 1997, pp. 7909-7914
OPTIMIZATION OF 3-(1H-INDAZOL-3-YLMETHYL)-1,5-BENZODIAZEPINES AS POTENT, ORALLY-ACTIVE CCK-A AGONISTS
Authors: HENKE BR AQUINO CJ BIRKEMO LS CROOM DK DOUGHERTY RW ERVIN GN GRIZZLE MK HIRST GC JAMES MK JOHNSON MF QUEEN KL SHERRILL RG SUGG EE SUH EM SZEWCZYK JW UNWALLA RJ YINGLING J WILLSON TM
Citation: Br. Henke et al., OPTIMIZATION OF 3-(1H-INDAZOL-3-YLMETHYL)-1,5-BENZODIAZEPINES AS POTENT, ORALLY-ACTIVE CCK-A AGONISTS, Journal of medicinal chemistry, 40(17), 1997, pp. 2706-2725
ACTIVATION OF THE NUCLEAR RECEPTOR LXR BY OXYSTEROLS DEFINES A NEW HORMONE RESPONSE PATHWAY
Authors: LEHMANN JM KLIEWER SA MOORE LB SMITHOLIVER TA OLIVER BB SU JL SUNDSETH SS WINEGAR DA BLANCHARD DE SPENCER TA WILLSON TM
Citation: Jm. Lehmann et al., ACTIVATION OF THE NUCLEAR RECEPTOR LXR BY OXYSTEROLS DEFINES A NEW HORMONE RESPONSE PATHWAY, The Journal of biological chemistry, 272(6), 1997, pp. 3137-3140
DISSECTION OF THE MOLECULAR MECHANISM OF ACTION OF GW5638, A NOVEL ESTROGEN-RECEPTOR LIGAND, PROVIDES INSIGHTS INTO THE ROLE OF ESTROGEN-RECEPTOR IN BONE
Authors: WILLSON TM NORRIS JD WAGNER BL ASPLIN I BAER P BROWN HR JONES SA HENKE B SAULS H WOLFE S MORRIS DC MCDONNELL DP
Citation: Tm. Willson et al., DISSECTION OF THE MOLECULAR MECHANISM OF ACTION OF GW5638, A NOVEL ESTROGEN-RECEPTOR LIGAND, PROVIDES INSIGHTS INTO THE ROLE OF ESTROGEN-RECEPTOR IN BONE, Endocrinology, 138(9), 1997, pp. 3901-3911
BONE TARGETED DRUGS .1. IDENTIFICATION OF HETEROCYCLES WITH HYDROXYAPATITE AFFINITY
Authors: WILLSON TM CHARIFSON PS BAXTER AD GEDDIE NG
Citation: Tm. Willson et al., BONE TARGETED DRUGS .1. IDENTIFICATION OF HETEROCYCLES WITH HYDROXYAPATITE AFFINITY, Bioorganic & medicinal chemistry letters, 6(9), 1996, pp. 1043-1046
BONE TARGETED DRUGS .2. SYNTHESIS OF ESTROGENS WITH HYDROXYAPATITE AFFINITY
Authors: WILLSON TM HENKE BR MOMTAHEN TM GARRISON DT MOORE LB GEDDIE NG BAER PG
Citation: Tm. Willson et al., BONE TARGETED DRUGS .2. SYNTHESIS OF ESTROGENS WITH HYDROXYAPATITE AFFINITY, Bioorganic & medicinal chemistry letters, 6(9), 1996, pp. 1047-1050
THE STRUCTURE-ACTIVITY RELATIONSHIP BETWEEN PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA AGONISM AND THE ANTIHYPERGLYCEMIC ACTIVITY OF THIAZOLIDINEDIONES
Authors: WILLSON TM COBB JE COWAN DJ WIETHE RW CORREA ID PRAKASH SR BECK KD MOORE LB KLIEWER SA LEHMANN JM
Citation: Tm. Willson et al., THE STRUCTURE-ACTIVITY RELATIONSHIP BETWEEN PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA AGONISM AND THE ANTIHYPERGLYCEMIC ACTIVITY OF THIAZOLIDINEDIONES, Journal of medicinal chemistry, 39(3), 1996, pp. 665-668
DISCOVERY OF 1,5-BENZODIAZEPINES WITH PERIPHERAL CHOLECYSTOKININ (CCK-A) RECEPTOR AGONIST ACTIVITY .2. OPTIMIZATION OF THE C3 AMINO SUBSTITUENT
Authors: HIRST GC AQUINO C BIRKEMO L CROOM DK DEZUBE M DOUGHERTY RW ERVIN GN GRIZZLE MK HENKE B JAMES MK JOHNSON MF MOMTAHEN T QUEEN KL SHERRILL RG SZEWCZYK J WILLSON TM SUGG EE
Citation: Gc. Hirst et al., DISCOVERY OF 1,5-BENZODIAZEPINES WITH PERIPHERAL CHOLECYSTOKININ (CCK-A) RECEPTOR AGONIST ACTIVITY .2. OPTIMIZATION OF THE C3 AMINO SUBSTITUENT, Journal of medicinal chemistry, 39(26), 1996, pp. 5236-5245
3-[2-(N-PHENYLACETAMIDE)]-1,5-BENZODIAZEPINES - ORALLY-ACTIVE, BINDING SELECTIVE CCK-A AGONISTS
Authors: WILLSON TM HENKE BR MOMTAHEN TM MYERS PL SUGG EE UNWALLA RJ CROOM DK DOUGHERTY RW GRIZZLE MK JOHNSON MF QUEEN KL RIMELE TJ YINGLING JD JAMES MK
Citation: Tm. Willson et al., 3-[2-(N-PHENYLACETAMIDE)]-1,5-BENZODIAZEPINES - ORALLY-ACTIVE, BINDING SELECTIVE CCK-A AGONISTS, Journal of medicinal chemistry, 39(15), 1996, pp. 3030-3034
3-(1H-INDAZOL-3-YLMETHYL)-1,5-BENZODIAZEPINES - CCK-A AGONISTS THAT DEMONSTRATE ORAL ACTIVITY AS SATIETY AGENTS
Authors: HENKE BR WILLSON TM SUGG EE CROOM DK DOUGHERTY RW QUEEN KL BIRKEMO LS ERVIN GN GRIZZLE MK JOHNSON MF JAMES MK
Citation: Br. Henke et al., 3-(1H-INDAZOL-3-YLMETHYL)-1,5-BENZODIAZEPINES - CCK-A AGONISTS THAT DEMONSTRATE ORAL ACTIVITY AS SATIETY AGENTS, Journal of medicinal chemistry, 39(14), 1996, pp. 2655-2658
A PROSTAGLANDIN J(2) METABOLITE BINDS PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA AND PROMOTES ADIPOCYTE DIFFERENTIATION
Authors: KLIEWER SA LENHARD JM WILLSON TM PATEL I MORRIS DC LEHMANN JM
Citation: Sa. Kliewer et al., A PROSTAGLANDIN J(2) METABOLITE BINDS PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA AND PROMOTES ADIPOCYTE DIFFERENTIATION, Cell, 83(5), 1995, pp. 813-819
Risultati: 1-25 | 26-28