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Results: 1-25 | 26-31
Results: 1-25/31
WHAT ARE THE PRACTICAL LIMITS FOR DETECTION OF MINOR NUCLEOSIDE REACTION-PRODUCTS WITH HPLC (UV DETECTION), 1H NMR, AND TLC (UV DETECTION)
Authors: ROBINS MJ SARKER S WNUK SF
Citation: Mj. Robins et al., WHAT ARE THE PRACTICAL LIMITS FOR DETECTION OF MINOR NUCLEOSIDE REACTION-PRODUCTS WITH HPLC (UV DETECTION), 1H NMR, AND TLC (UV DETECTION), Nucleosides & nucleotides, 17(4), 1998, pp. 785-790
SYNTHESIS OF HOMOLOGATED HALOVINYL DERIVATIVES FROM ARISTEROMYCIN ANDTHEIR INHIBITION OF HUMAN PLACENTAL S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE
Authors: WNUK SF YUAN CS BORCHARDT RT ROBINS MJ
Citation: Sf. Wnuk et al., SYNTHESIS OF HOMOLOGATED HALOVINYL DERIVATIVES FROM ARISTEROMYCIN ANDTHEIR INHIBITION OF HUMAN PLACENTAL S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE, Nucleosides & nucleotides, 17(1-3), 1998, pp. 99-113
NUCLEIC-ACID RELATED-COMPOUNDS - 101 - S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE DOES NOT HYDRATE (5'-FLUORO)VINYL OR (6'-HALO)HOMOVINYL ANALOGS DERIVED FROM 3'-DEOXYADENOSINE OR 3'-(CHLORO OR FLUORO)-3'-DEOXYADENOSINE
Authors: ROBINS MJ NESCHADIMENKO V RO BO YUAN CS BORCHARDT RT WNUK SF
Citation: Mj. Robins et al., NUCLEIC-ACID RELATED-COMPOUNDS - 101 - S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE DOES NOT HYDRATE (5'-FLUORO)VINYL OR (6'-HALO)HOMOVINYL ANALOGS DERIVED FROM 3'-DEOXYADENOSINE OR 3'-(CHLORO OR FLUORO)-3'-DEOXYADENOSINE, Journal of organic chemistry, 63(4), 1998, pp. 1205-1211
NUCLEIC-ACID RELATED-COMPOUNDS - 105 - SYNTHESIS OF 2',3'-DIDEHYDRO-2',3'-DIDEOXYNUCLEOSIDES FROM RIBONUCLEOSIDE CYCLIC 2',3'-(SULFATES OR PHOSPHATES) OR 2',3'-DIMESYLATES VIA REDUCTIVE ELIMINATION WITH SODIUMNAPHTHALENIDE
Authors: ROBINS MJ LEWANDOWSKA E WNUK SF
Citation: Mj. Robins et al., NUCLEIC-ACID RELATED-COMPOUNDS - 105 - SYNTHESIS OF 2',3'-DIDEHYDRO-2',3'-DIDEOXYNUCLEOSIDES FROM RIBONUCLEOSIDE CYCLIC 2',3'-(SULFATES OR PHOSPHATES) OR 2',3'-DIMESYLATES VIA REDUCTIVE ELIMINATION WITH SODIUMNAPHTHALENIDE, Journal of organic chemistry, 63(21), 1998, pp. 7375-7381
INACTIVATION OF S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE AND ANTIVIRAL ACTIVITY WITH ',6',6'-TETRADEHYDRO-6'-DEOXY-6'-HALOHOMOADENOSINE ANALOGS (4'-HALOACETYLENE ANALOGS DERIVED FROM ADENOSINE)
Authors: ROBINS MJ WNUK SF YANG XD YUAN CS BORCHARDT RT BALZARINI J DECLERCQ E
Citation: Mj. Robins et al., INACTIVATION OF S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE AND ANTIVIRAL ACTIVITY WITH ',6',6'-TETRADEHYDRO-6'-DEOXY-6'-HALOHOMOADENOSINE ANALOGS (4'-HALOACETYLENE ANALOGS DERIVED FROM ADENOSINE), Journal of medicinal chemistry, 41(20), 1998, pp. 3857-3864
DISCOVERY OF TYPE-II (COVALENT) INACTIVATION OF S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE INVOLVING ITS HYDROLYTIC ACTIVITY - SYNTHESIS AND EVALUATION OF DIHALOHOMOVINYL NUCLEOSIDE ANALOGS DERIVED FROM ADENOSINE
Authors: WNUK SF MAO Y YUAN CS BORCHARDT RT ANDREI G BALZARINI J DECLERCQ E ROBINS MJ
Citation: Sf. Wnuk et al., DISCOVERY OF TYPE-II (COVALENT) INACTIVATION OF S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE INVOLVING ITS HYDROLYTIC ACTIVITY - SYNTHESIS AND EVALUATION OF DIHALOHOMOVINYL NUCLEOSIDE ANALOGS DERIVED FROM ADENOSINE, Journal of medicinal chemistry, 41(16), 1998, pp. 3078-3083
A NOVEL MECHANISM-BASED INHIBITOR O-5',6'-DIDEHYDRO-6'-DEOXY-6'-FLUOROHOMOADENOSINE) THAT COVALENTLY MODIFIES HUMAN PLACENTAL S-ADENOSYLHOMOCYSTEINE HYDROLASE
Authors: YUAN CS WNUK SF ROBINS MJ BORCHARDT RT
Citation: Cs. Yuan et al., A NOVEL MECHANISM-BASED INHIBITOR O-5',6'-DIDEHYDRO-6'-DEOXY-6'-FLUOROHOMOADENOSINE) THAT COVALENTLY MODIFIES HUMAN PLACENTAL S-ADENOSYLHOMOCYSTEINE HYDROLASE, The Journal of biological chemistry, 273(29), 1998, pp. 18191-18197
A NOVEL MECHANISM-BASED INHIBITOR ROMO-5',6'-DIDEHYDRO-DEOXY-6'-FLUOROHOMOADENOSINE) THAT COVALENTLY MODIFIES HUMAN PLACENTAL S-ADENOSYLHOMOCYSTEINE HYDROLASE
Authors: YUAN CS WNUK SF ROBINS MJ BORCHARDT RT
Citation: Cs. Yuan et al., A NOVEL MECHANISM-BASED INHIBITOR ROMO-5',6'-DIDEHYDRO-DEOXY-6'-FLUOROHOMOADENOSINE) THAT COVALENTLY MODIFIES HUMAN PLACENTAL S-ADENOSYLHOMOCYSTEINE HYDROLASE, The FASEB journal, 11(9), 1997, pp. 949-949
NUCLEIC-ACID RELATED-COMPOUNDS .94. REMARKABLY HIGH STEREOSELECTIVE REDUCTIONS OF 2'-KETONUCLEOSIDE AND 3'-KETONUCLEOSIDE DERIVATIVES TO GIVE ARABINO, RIBO, AND XYLOFURANOSYL NUCLEOSIDES WITH HYDROGEN ISOTOPESAT C2' AND C3'
Authors: ROBINS MJ SARKER S SAMANO V WNUK SF
Citation: Mj. Robins et al., NUCLEIC-ACID RELATED-COMPOUNDS .94. REMARKABLY HIGH STEREOSELECTIVE REDUCTIONS OF 2'-KETONUCLEOSIDE AND 3'-KETONUCLEOSIDE DERIVATIVES TO GIVE ARABINO, RIBO, AND XYLOFURANOSYL NUCLEOSIDES WITH HYDROGEN ISOTOPESAT C2' AND C3', Tetrahedron, 53(2), 1997, pp. 447-456
EFFICIENT REMOVAL OF SUGAR O-TOSYL GROUPS AND HETEROCYCLE HALOGENS FROM PURINE NUCLEOSIDES WITH SODIUM NAPHTHALENIDE
Authors: LEWANDOWSKA E NESCHADIMENKO V WNUK SF ROBINS MJ
Citation: E. Lewandowska et al., EFFICIENT REMOVAL OF SUGAR O-TOSYL GROUPS AND HETEROCYCLE HALOGENS FROM PURINE NUCLEOSIDES WITH SODIUM NAPHTHALENIDE, Tetrahedron, 53(18), 1997, pp. 6295-6302
ANTICANCER AND ANTIVIRAL EFFECTS AND INACTIVATION OF S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE WITH 5'-CARBOXALDEHYDES AND OXIMES SYNTHESIZED FROM ADENOSINE AND SUGAR-MODIFIED ANALOGS
Authors: WNUK SF YUAN CS BORCHARDT RT BALZARINI J DECLERCQ E ROBINS MJ
Citation: Sf. Wnuk et al., ANTICANCER AND ANTIVIRAL EFFECTS AND INACTIVATION OF S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE WITH 5'-CARBOXALDEHYDES AND OXIMES SYNTHESIZED FROM ADENOSINE AND SUGAR-MODIFIED ANALOGS, Journal of medicinal chemistry, 40(11), 1997, pp. 1608-1618
SYNTHESIS OF SUGAR-MODIFIED 2,6-DIAMINOPURINE AND GUANINE NUCLEOSIDESFROM GUANOSINE VIA TRANSFORMATIONS OF 2-AMINOADENOSINE AND ENZYMATIC DEAMINATION WITH ADENOSINE-DEAMINASE
Authors: ROBINS MJ ZOU RM HANSSKE F WNUK SF
Citation: Mj. Robins et al., SYNTHESIS OF SUGAR-MODIFIED 2,6-DIAMINOPURINE AND GUANINE NUCLEOSIDESFROM GUANOSINE VIA TRANSFORMATIONS OF 2-AMINOADENOSINE AND ENZYMATIC DEAMINATION WITH ADENOSINE-DEAMINASE, Canadian journal of chemistry, 75(6), 1997, pp. 762-767
THE MECHANISM OF INACTIVATION OF HUMAN PLACENTAL S-ADENOSYLHOMOCYSTEINE HYDROLASE BY (E)-4',5'DIDEHYDRO-5'-METHOXYADENOSINE AND ADENOSINE 5'-CARBOXALDEHYDE OXIME
Authors: HUANG H YUAN CS WNUK SF ROBINS MJ BORCHARDT RT
Citation: H. Huang et al., THE MECHANISM OF INACTIVATION OF HUMAN PLACENTAL S-ADENOSYLHOMOCYSTEINE HYDROLASE BY (E)-4',5'DIDEHYDRO-5'-METHOXYADENOSINE AND ADENOSINE 5'-CARBOXALDEHYDE OXIME, Archives of biochemistry and biophysics, 343(1), 1997, pp. 109-117
ELIMINATION OF CHLORINE (RADICAL) OR TOSYLATE (ANION) FROM C2' OF NUCLEOSIDE C3' FREE-RADICALS AS MODEL REACTIONS POSTULATED TO OCCUR AT THE ACTIVE-SITE OF RIBONUCLEOTIDE REDUCTASES
Authors: ROBINS MJ GUO ZQ WNUK SF
Citation: Mj. Robins et al., ELIMINATION OF CHLORINE (RADICAL) OR TOSYLATE (ANION) FROM C2' OF NUCLEOSIDE C3' FREE-RADICALS AS MODEL REACTIONS POSTULATED TO OCCUR AT THE ACTIVE-SITE OF RIBONUCLEOTIDE REDUCTASES, Journal of the American Chemical Society, 119(15), 1997, pp. 3637-3638
THE MECHANISMS OF INACTIVATION OF HUMAN PLACENTAL S-ADENOSYLHOMOCYSTEINE HYDROLASE BY (E)-4',5'-DIDEHYDRO-5'-METHOXYADENOSINE (DMOA) AND ADENOSINE 5'-CARBOXALDEHYDE OXIME (ACAO)
Authors: HUANG H YUAN CS BORCHARDT RT WNUK SF ROBINS MJ
Citation: H. Huang et al., THE MECHANISMS OF INACTIVATION OF HUMAN PLACENTAL S-ADENOSYLHOMOCYSTEINE HYDROLASE BY (E)-4',5'-DIDEHYDRO-5'-METHOXYADENOSINE (DMOA) AND ADENOSINE 5'-CARBOXALDEHYDE OXIME (ACAO), The FASEB journal, 10(6), 1996, pp. 1415-1415
NUCLEIC-ACID RELATED-COMPOUNDS .93. A SOLUTION FOR THE HISTORIC PROBLEM OF REGIOSELECTIVE SUGAR-BASE COUPLING TO PRODUCE 9-GLYCOSYLGUANINESOR 7-GLYCOSYLGUANINES
Authors: ROBINS MJ ZOU RM GUO ZQ WNUK SF
Citation: Mj. Robins et al., NUCLEIC-ACID RELATED-COMPOUNDS .93. A SOLUTION FOR THE HISTORIC PROBLEM OF REGIOSELECTIVE SUGAR-BASE COUPLING TO PRODUCE 9-GLYCOSYLGUANINESOR 7-GLYCOSYLGUANINES, Journal of organic chemistry, 61(26), 1996, pp. 9207-9212
INACTIVATION OF S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE BY AMIDE AND ESTER DERIVATIVES OF ADENOSINE-5'-CARBOXYLIC ACID
Authors: WNUK SF LIU SM YUAN CS BORCHARDT RT ROBINS MJ
Citation: Sf. Wnuk et al., INACTIVATION OF S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE BY AMIDE AND ESTER DERIVATIVES OF ADENOSINE-5'-CARBOXYLIC ACID, Journal of medicinal chemistry, 39(21), 1996, pp. 4162-4166
NUCLEIC-ACID RELATED-COMPOUNDS .91. BIOMIMETIC REACTIONS ARE IN HARMONY WITH LOSS OF 2'-SUBSTITUENTS AS FREE-RADICALS (NOT ANIONS) DURING MECHANISM-BASED INACTIVATION OF RIBONUCLEOTIDE REDUCTASES - DIFFERENTIAL INTERACTIONS OF AZIDE, HALOGEN, AND ALKYLTHIO GROUPS WITH TRIBUTYLSTANNANE AND TRIPHENYLSILANE
Authors: ROBINS MJ WNUK SF HERNANDEZTHIRRING AE SAMANO MC
Citation: Mj. Robins et al., NUCLEIC-ACID RELATED-COMPOUNDS .91. BIOMIMETIC REACTIONS ARE IN HARMONY WITH LOSS OF 2'-SUBSTITUENTS AS FREE-RADICALS (NOT ANIONS) DURING MECHANISM-BASED INACTIVATION OF RIBONUCLEOTIDE REDUCTASES - DIFFERENTIAL INTERACTIONS OF AZIDE, HALOGEN, AND ALKYLTHIO GROUPS WITH TRIBUTYLSTANNANE AND TRIPHENYLSILANE, Journal of the American Chemical Society, 118(46), 1996, pp. 11341-11348
BIOMIMETIC MODELING OF THE DECOMPOSITION OF 2'-CHLORO-2'-DEOXYNUCLEOTIDES BY RIBONUCLEOTIDE REDUCTASES TO GIVE 3(2H)-FURANONES WHICH CAN EFFECT MECHANISM-BASED INACTIVATION BY MICHAEL-TYPE ALKYLATION
Authors: ROBINS MJ GUO ZQ SAMANO MC WNUK SF
Citation: Mj. Robins et al., BIOMIMETIC MODELING OF THE DECOMPOSITION OF 2'-CHLORO-2'-DEOXYNUCLEOTIDES BY RIBONUCLEOTIDE REDUCTASES TO GIVE 3(2H)-FURANONES WHICH CAN EFFECT MECHANISM-BASED INACTIVATION BY MICHAEL-TYPE ALKYLATION, Journal of the American Chemical Society, 118(45), 1996, pp. 11317-11318
STANNYL RADICAL-MEDIATED CLEAVAGE OF PI-DEFICIENT HETEROCYCLIC SULFONES - SYNTHESIS OF ALPHA-FLUORO ESTERS AND THE FIRST HOMONUCLEOSIDE ALPHA-FLUOROMETHYLENE PHOSPHONATE
Authors: WNUK SF ROBINS MJ
Citation: Sf. Wnuk et Mj. Robins, STANNYL RADICAL-MEDIATED CLEAVAGE OF PI-DEFICIENT HETEROCYCLIC SULFONES - SYNTHESIS OF ALPHA-FLUORO ESTERS AND THE FIRST HOMONUCLEOSIDE ALPHA-FLUOROMETHYLENE PHOSPHONATE, Journal of the American Chemical Society, 118(10), 1996, pp. 2519-2520
RATIONAL APPROACHES TO THE DESIGN OF MECHANISM-BASED INHIBITORS OF S-ADENOSYLHOMOCYSTEINE HYDROLASE
Authors: YUAN CS LIU SM WNUK SF ROBINS MJ BORCHARDT RT
Citation: Cs. Yuan et al., RATIONAL APPROACHES TO THE DESIGN OF MECHANISM-BASED INHIBITORS OF S-ADENOSYLHOMOCYSTEINE HYDROLASE, Nucleosides & nucleotides, 14(3-5), 1995, pp. 439-447
NUCLEIC-ACID RELATED-COMPOUNDS .88. EFFICIENT CONVERSIONS OF RIBONUCLEOSIDES INTO THEIR 2',3'-ANHYDRO, 2'(AND 3')-DEOXY, 2',3'-DIDEHYDRO-2',3'-DIDEOXY, AND 2',3'-DIDEOXYNUCLEOSIDE ANALOGS
Authors: ROBINS MJ WILSON JS MADEJ D LOW NH HANSSKE F WNUK SF
Citation: Mj. Robins et al., NUCLEIC-ACID RELATED-COMPOUNDS .88. EFFICIENT CONVERSIONS OF RIBONUCLEOSIDES INTO THEIR 2',3'-ANHYDRO, 2'(AND 3')-DEOXY, 2',3'-DIDEHYDRO-2',3'-DIDEOXY, AND 2',3'-DIDEOXYNUCLEOSIDE ANALOGS, Journal of organic chemistry, 60(24), 1995, pp. 7902-7908
SELECTED ASPECTS OF THE CHEMISTRY AND BIOCHEMISTRY OF SULFUR-CONTAINING NUCLEOSIDES
Authors: ROBINS MJ WNUK SF
Citation: Mj. Robins et Sf. Wnuk, SELECTED ASPECTS OF THE CHEMISTRY AND BIOCHEMISTRY OF SULFUR-CONTAINING NUCLEOSIDES, Phosphorus, sulfur and silicon and the related elements, 95-6(1-4), 1994, pp. 71-88
)-5',6'-DIDEHYDRO-6'-DEOXY-6'-FLUORO-HOMOADENOSINE (EDDFHA) - A SUBSTRATE THAT MEASURES THE HYDROLYTIC ACTIVITY OF S-ADENOSYL-L-HOMOCYSTEINE (ADOHCY) HYDROLASE
Authors: YUAN CS WNUK SF LIU S ROBINS MJ BORCHARDT RT
Citation: Cs. Yuan et al., )-5',6'-DIDEHYDRO-6'-DEOXY-6'-FLUORO-HOMOADENOSINE (EDDFHA) - A SUBSTRATE THAT MEASURES THE HYDROLYTIC ACTIVITY OF S-ADENOSYL-L-HOMOCYSTEINE (ADOHCY) HYDROLASE, The FASEB journal, 8(7), 1994, pp. 10001412-10001412
NUCLEIC-ACID RELATED-COMPOUNDS .82. CONVERSIONS OF ADENOSINE TO INOSINE 5-BETA-THIOETHER DERIVATIVES WITH ASPERGILLUS-ORYZAE ADENOSINE-DEAMINASE OR ALKYL NITRATES - SUBSTRATE AND INHIBITORY ACTIVITIES OF INOSINE 5'-THIOETHER DERIVATIVES WITH PURINE NUCLEOSIDE PHOSPHORYLASE
Authors: WNUK SF STOECKLER JD ROBINS MJ
Citation: Sf. Wnuk et al., NUCLEIC-ACID RELATED-COMPOUNDS .82. CONVERSIONS OF ADENOSINE TO INOSINE 5-BETA-THIOETHER DERIVATIVES WITH ASPERGILLUS-ORYZAE ADENOSINE-DEAMINASE OR ALKYL NITRATES - SUBSTRATE AND INHIBITORY ACTIVITIES OF INOSINE 5'-THIOETHER DERIVATIVES WITH PURINE NUCLEOSIDE PHOSPHORYLASE, Nucleosides & nucleotides, 13(1-3), 1994, pp. 389-403
Risultati: 1-25 | 26-31