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Results: 1-25/31
Authors:
Wolfe, MS
Citation: Ms. Wolfe, gamma-secretase inhibitors as molecular probes of presenilin function, J MOL NEURO, 17(2), 2001, pp. 199-204
Authors:
Jack, C
Berezovska, O
Wolfe, MS
Hyman, BT
Citation: C. Jack et al., Effect of PS1 deficiency and an APP gamma-secretase inhibitor on Notch1 signaling in primary mammalian neurons, MOL BRAIN R, 87(2), 2001, pp. 166-174
Authors:
Stockdale, EA
Lampkin, NH
Hovi, M
Keatinge, R
Lennartsson, EKM
Macdonald, DW
Padel, S
Tattersall, FH
Wolfe, MS
Watson, CA
Citation: Ea. Stockdale et al., Agronomic and environmental implications of organic farming systems, ADV AGRON, 70, 2001, pp. 261-327
Authors:
Esler, WP
Wolfe, MS
Citation: Wp. Esler et Ms. Wolfe, Biomedicine - A portrait of Alzheimer secretases - New features and familiar faces, SCIENCE, 293(5534), 2001, pp. 1449-1454
Authors:
Hadland, BK
Manley, NR
Su, DM
Longmore, GD
Moore, CL
Wolfe, MS
Schroeter, EH
Kopan, R
Citation: Bk. Hadland et al., gamma-secretase inhibitors repress thymocyte development, P NAS US, 98(13), 2001, pp. 7487-7491
Authors:
Wolfe, MS
Citation: Ms. Wolfe, Presenilin and gamma-secretase: structure meets function, J NEUROCHEM, 76(6), 2001, pp. 1615-1620
Authors:
Wolfe, MS
Citation: Ms. Wolfe, Secretase targets for Alzheimer's disease: Identification and therapeutic potential, J MED CHEM, 44(13), 2001, pp. 2039-2060
Authors:
Wolfe, MS
Haass, C
Citation: Ms. Wolfe et C. Haass, The role of presenilins in gamma-secretase activity, J BIOL CHEM, 276(8), 2001, pp. 5413-5416
Authors:
Selkoe, DJ
Xia, W
Kimberly, WT
Vekrellis, K
Walsh, D
Esler, WP
Wolfe, MS
Citation: Dj. Selkoe et al., Mechanisms of A beta production and A beta degradation: Routes to the treatment of Alzheimer's disease, ALZHEIMER'S DISEASE, 2001, pp. 421-432
Authors:
Esler, WP
Kimberly, WT
Ostaszewski, BL
Xia, WM
Selkoe, DJ
Wolfe, MS
Citation: Wp. Esler et al., Toward the identification of gamma-secretase: Using transition state analog inhibitors, ALZHEIMER'S DISEASE, 2001, pp. 777-788
Authors:
Esler, WP
Kimberly, WT
Ostaszewski, BL
Diehl, TS
Moore, CL
Tsai, JY
Rahmati, T
Xia, WM
Selkoe, DJ
Wolfe, MS
Citation: Wp. Esler et al., Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1, NAT CELL BI, 2(7), 2000, pp. 428-434
Authors:
Xia, WM
Ostaszewski, BL
Kimberly, WT
Rahmati, T
Moore, CL
Wolfe, MS
Selkoe, DJ
Citation: Wm. Xia et al., FAD mutations in presenilin-1 or amyloid precursor protein decrease the efficacy of a gamma-secretase inhibitor: Evidence for direct involvement of PS1 in the gamma-secretase cleavage complex, NEUROBIOL D, 7(6), 2000, pp. 673-681
Authors:
Johnson, JA
Akers, WS
Herring, VL
Wolfe, MS
Sullivan, JM
Citation: Ja. Johnson et al., Gender differences in labetalol kinetics: Importance of determining stereoisomer kinetics for racemic drugs, PHARMACOTHE, 20(6), 2000, pp. 622-628
Authors:
Finckh, MR
Gacek, ES
Goyeau, H
Lannou, C
Merz, U
Mundt, CC
Munk, L
Nadziak, J
Newton, AC
de Vallavieille-Pope, C
Wolfe, MS
Citation: Mr. Finckh et al., Cereal variety and species mixtures in practice, with emphasis on disease resistance, AGRONOMIE, 20(7), 2000, pp. 813-837
Authors:
Wolfe, MS
Citation: Ms. Wolfe, Crop strength through diversity, NATURE, 406(6797), 2000, pp. 681-682
Authors:
Xia, WM
Ray, WJ
Ostaszewski, BL
Rahmati, T
Kimberly, WT
Wolfe, MS
Zhang, JM
Goate, AM
Selkoe, DJ
Citation: Wm. Xia et al., Presenilin complexes with the C-terminal fragments of amyloid precursor protein at the sites of amyloid beta-protein generation, P NAS US, 97(16), 2000, pp. 9299-9304
Authors:
Selkoe, DJ
Wolfe, MS
Citation: Dj. Selkoe et Ms. Wolfe, In search of gamma-secretase: Presenilin at the cutting edge, P NAS US, 97(11), 2000, pp. 5690-5692
Authors:
Johnson, JA
Herring, VL
Wolfe, MS
Relling, MV
Citation: Ja. Johnson et al., CYP1A2 and CYP2D6 4-hydroxylate propranolol and both reactions exhibit racial differences, J PHARM EXP, 294(3), 2000, pp. 1099-1105
Authors:
Berezovska, O
Jack, C
McLean, P
Aster, JC
Hicks, C
Xia, WM
Wolfe, MS
Kimberly, WT
Weinmaster, G
Selkoe, DJ
Hyman, BT
Citation: O. Berezovska et al., Aspartate mutations in presenilin and gamma-secretase inhibitors both impair Notch1 proteolysis and nuclear translocation with relative preservation of Notch1 signaling, J NEUROCHEM, 75(2), 2000, pp. 583-593
Authors:
Moore, CL
Leatherwood, DD
Diehl, TS
Selkoe, DJ
Wolfe, MS
Citation: Cl. Moore et al., Difluoro ketone peptidomimetics suggest a large S1 pocket for Alzheimer's gamma-secretase: Implications for inhibitor design, J MED CHEM, 43(18), 2000, pp. 3434-3442
Authors:
Kimberly, WT
Xia, WM
Rahmati, T
Wolfe, MS
Selkoe, DJ
Citation: Wt. Kimberly et al., The transmembrane aspartates in presenilin 1 and 2 are obligatory for gamma-secretase activity and amyloid beta-protein generation, J BIOL CHEM, 275(5), 2000, pp. 3173-3178
Authors:
Moore, CL
Wolfe, MS
Citation: Cl. Moore et Ms. Wolfe, Inhibition of beta-amyloid formation as a therapeutic strategy, EXPERT OP T, 9(2), 1999, pp. 135-146
Authors:
Wolfe, MS
Citation: Ms. Wolfe, Re: Letter an quinacrine for treatment of Giardiasis - J Travel Med 1998;5: 228. Reply, J TRAVEL M, 6(4), 1999, pp. 265-265
Authors:
Wolfe, MS
Citation: Ms. Wolfe, Travel medicine, CURR OPIN I, 12(5), 1999, pp. 433-438
Authors:
Finckh, MR
Gacek, ES
Czembor, HJ
Wolfe, MS
Citation: Mr. Finckh et al., Host frequency and density effects on powdery mildew and yield in mixturesof barley cultivars, PLANT PATH, 48(6), 1999, pp. 807-816