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Results: 1-25 |
Results: 25
SYNTHESIS AND INHIBITORY ACTIVITY OF NOVEL TRICYCLIC AND TETRACYCLIC QUINOLINES AGAINST TOPOISOMERASES
Authors: SUI ZH ALTOM J NGUYEN V FERNANDEZ J BERNSTEIN JI HILIARD JJ BARRETT JF PODLOGAR BL OHEMENG KA
Citation: Zh. Sui et al., SYNTHESIS AND INHIBITORY ACTIVITY OF NOVEL TRICYCLIC AND TETRACYCLIC QUINOLINES AGAINST TOPOISOMERASES, Bioorganic & medicinal chemistry, 6(6), 1998, pp. 735-742
NOVEL INHIBITORS OF BACTERIAL 2-COMPONENT SYSTEMS WITH GRAM-POSITIVE ANTIBACTERIAL ACTIVITY - PHARMACOPHORE IDENTIFICATION BASED ON THE SCREENING HIT CLOSANTEL
Authors: HLASTA DJ DEMERS JP FOLENO BD FRAGASPANO SA GUAN JH HILLIARD JJ MACIELAG MJ OHEMENG KA SHEPPARD CM SUI ZH WEBB GC WEIDNERWELLS MA WERBLOOD H BARRETT JF
Citation: Dj. Hlasta et al., NOVEL INHIBITORS OF BACTERIAL 2-COMPONENT SYSTEMS WITH GRAM-POSITIVE ANTIBACTERIAL ACTIVITY - PHARMACOPHORE IDENTIFICATION BASED ON THE SCREENING HIT CLOSANTEL, Bioorganic & medicinal chemistry letters, 8(14), 1998, pp. 1923-1928
SAR STUDIES OF DIARYLTRIAZOLES AGAINST BACTERIAL 2-COMPONENT REGULATORY SYSTEMS AND THEIR ANTIBACTERIAL ACTIVITIES
Authors: SUI ZH GUAN JH HLASTA DJ MACIELAG MJ FOLENO BD GOLDSCHMIDT RM LOELOFF MJ WEBB GC BARRETT JF
Citation: Zh. Sui et al., SAR STUDIES OF DIARYLTRIAZOLES AGAINST BACTERIAL 2-COMPONENT REGULATORY SYSTEMS AND THEIR ANTIBACTERIAL ACTIVITIES, Bioorganic & medicinal chemistry letters, 8(14), 1998, pp. 1929-1934
DNA GYRASE INHIBITORY ACTIVITY OF ELLAGIC ACID-DERIVATIVES
Authors: WEIDNERWELLS MA ALTOM J FERNANDEZ J FRAGASPANO SA HILLIARD J OHEMENG K BARRETT JF
Citation: Ma. Weidnerwells et al., DNA GYRASE INHIBITORY ACTIVITY OF ELLAGIC ACID-DERIVATIVES, Bioorganic & medicinal chemistry letters, 8(1), 1998, pp. 97-100
2-COMPONENT SIGNAL-TRANSDUCTION AS A TARGET FOR MICROBIAL ANTIINFECTIVE THERAPY
Authors: BARRETT JF HOCH JA
Citation: Jf. Barrett et Ja. Hoch, 2-COMPONENT SIGNAL-TRANSDUCTION AS A TARGET FOR MICROBIAL ANTIINFECTIVE THERAPY, Antimicrobial agents and chemotherapy, 42(7), 1998, pp. 1529-1536
ANTIBACTERIAL AGENTS THAT INHIBIT 2-COMPONENT SIGNAL-TRANSDUCTION SYSTEMS
Authors: BARRETT JF GOLDSCHMIDT RM LAWRENCE LE FOLENO B CHEN R DEMERS JP JOHNSON S KANOJIA R FERNANDEZ J BERNSTEIN J LICATA L DONETZ A HUANG S HLASTA DJ MACIELAG MJ OHEMENG K FRECHETTE R FROSCO MB KLAUBERT DH WHITELEY JM WANG L HOCH JA
Citation: Jf. Barrett et al., ANTIBACTERIAL AGENTS THAT INHIBIT 2-COMPONENT SIGNAL-TRANSDUCTION SYSTEMS, Proceedings of the National Academy of Sciences of the United Statesof America, 95(9), 1998, pp. 5317-5322
SUBSTITUTED SALICYLANILIDES AS INHIBITORS OF 2-COMPONENT REGULATORY SYSTEMS IN BACTERIA
Authors: MACIELAG MJ DEMERS JP FRAGASPANO SA HLASTA DJ JOHNSON SG KANOJIA RM RUSSEL RK SUI ZH WEIDNERWELLS MA WERBLOOD H FOLENO BD GOLDSCHMIDT RM LOELOFF MJ WEBB GC BARRETT JF
Citation: Mj. Macielag et al., SUBSTITUTED SALICYLANILIDES AS INHIBITORS OF 2-COMPONENT REGULATORY SYSTEMS IN BACTERIA, Journal of medicinal chemistry, 41(16), 1998, pp. 2939-2945
ASSESSMENT OF THE SYNERGISTIC INTERACTIONS OF LEVOFLOXACIN AND AMPICILLIN AGAINST ENTEROCOCCUS-FAECIUM BY THE CHECKERBOARD AGAR DILUTION AND TIME-KILL METHODS
Authors: SMITH CE FOLENO BE BARRETT JF FROSCO MB
Citation: Ce. Smith et al., ASSESSMENT OF THE SYNERGISTIC INTERACTIONS OF LEVOFLOXACIN AND AMPICILLIN AGAINST ENTEROCOCCUS-FAECIUM BY THE CHECKERBOARD AGAR DILUTION AND TIME-KILL METHODS, Diagnostic microbiology and infectious disease, 27(3), 1997, pp. 85-92
COMPARISON OF THE POSTANTIBIOTIC AND POSTANTIBIOTIC SUB-MIC EFFECTS OF LEVOFLOXACIN AND CIPROFLOXACIN ON STAPHYLOCOCCUS-AUREUS AND STREPTOCOCCUS-PNEUMONIAE
Authors: LICATA L SMITH CE GOLDSCHMIDT RM BARRETT JF FROSCO M
Citation: L. Licata et al., COMPARISON OF THE POSTANTIBIOTIC AND POSTANTIBIOTIC SUB-MIC EFFECTS OF LEVOFLOXACIN AND CIPROFLOXACIN ON STAPHYLOCOCCUS-AUREUS AND STREPTOCOCCUS-PNEUMONIAE, Antimicrobial agents and chemotherapy, 41(5), 1997, pp. 950-955
PROTEIN STRUCTURE DETERMINATION USING A COMBINATION OF COMPARATIVE MODELING AND NMR-SPECTROSCOPY - APPLICATION TO THE RESPONSE REGULATOR PROTEIN, SPO0F
Authors: PODLOGAR BL LEO GC MCDONNELL PA LOUGHNEY DA CALDWELL GW BARRETT JF
Citation: Bl. Podlogar et al., PROTEIN STRUCTURE DETERMINATION USING A COMBINATION OF COMPARATIVE MODELING AND NMR-SPECTROSCOPY - APPLICATION TO THE RESPONSE REGULATOR PROTEIN, SPO0F, Journal of medicinal chemistry, 40(21), 1997, pp. 3453-3455
DNA GYRASE INHIBITORY AND ANTIMICROBIAL ACTIVITIES OF SOME DIPHENIC ACID MONOHYDROXAMIDES
Authors: OHEMENG KA PODLOGAR BL NGUYEN VN BERNSTEIN JI KRAUSE HM HILLIARD JJ BARRETT JF
Citation: Ka. Ohemeng et al., DNA GYRASE INHIBITORY AND ANTIMICROBIAL ACTIVITIES OF SOME DIPHENIC ACID MONOHYDROXAMIDES, Journal of medicinal chemistry, 40(20), 1997, pp. 3292-3296
SYNTHESIS OF 2-SUBSTITUTED 4-QUINAZOLONE-5-CARBOXYLIC ACIDS AS INHIBITORS OF DNA-GYRASE
Authors: SUI ZH NGUYEN VN FERNANDEZ J BARRETT JF OHEMENG KA
Citation: Zh. Sui et al., SYNTHESIS OF 2-SUBSTITUTED 4-QUINAZOLONE-5-CARBOXYLIC ACIDS AS INHIBITORS OF DNA-GYRASE, Journal of heterocyclic chemistry, 34(1), 1997, pp. 153-156
SYNTHESIS OF A SERIES OF CYTOTOXIC 2-ACYL-1,2-DIHYDROELLIPTICINES WHICH INHIBIT TOPOISOMERASE-II
Authors: DEVRAJ R JURAYJ J FERNANDEZ JA BARRETT JF CUSHMAN M
Citation: R. Devraj et al., SYNTHESIS OF A SERIES OF CYTOTOXIC 2-ACYL-1,2-DIHYDROELLIPTICINES WHICH INHIBIT TOPOISOMERASE-II, Anti-cancer drug design, 11(4), 1996, pp. 311-324
IN-VIVO ORAL EFFICACY OF LEVOFLOXACIN FOR TREATMENT OF SYSTEMIC PSEUDOMONAS-AERUGINOSA INFECTIONS IN A MURINE MODEL OF SEPTICEMIA
Authors: YAGEL SK BARRETT JF AMARATUNGA DJ FROSCO MB
Citation: Sk. Yagel et al., IN-VIVO ORAL EFFICACY OF LEVOFLOXACIN FOR TREATMENT OF SYSTEMIC PSEUDOMONAS-AERUGINOSA INFECTIONS IN A MURINE MODEL OF SEPTICEMIA, Antimicrobial agents and chemotherapy, 40(12), 1996, pp. 2894-2897
IN-VIVO EFFICACIES OF LEVOFLOXACIN AND CIPROFLOXACIN IN ACUTE MURINE HEMATOGENOUS PYELONEPHRITIS INDUCED BY METHICILLIN-SUSCEPTIBLE AND METHICILLIN-RESISTANT STAPHYLOCOCCUS-AUREUS STRAINS
Authors: FROSCO MB MELTON JL STEWART FP KULWICH BA LICATA L BARRETT JF
Citation: Mb. Frosco et al., IN-VIVO EFFICACIES OF LEVOFLOXACIN AND CIPROFLOXACIN IN ACUTE MURINE HEMATOGENOUS PYELONEPHRITIS INDUCED BY METHICILLIN-SUSCEPTIBLE AND METHICILLIN-RESISTANT STAPHYLOCOCCUS-AUREUS STRAINS, Antimicrobial agents and chemotherapy, 40(11), 1996, pp. 2529-2534
DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION OF ELLIPTICINE-ESTRADIOLCONJUGATES
Authors: DEVRAJ R BARRETT JF FERNANDEZ JA KATZENELLENBOGEN JA CUSHMAN M
Citation: R. Devraj et al., DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION OF ELLIPTICINE-ESTRADIOLCONJUGATES, Journal of medicinal chemistry, 39(17), 1996, pp. 3367-3374
HUMAN T-CELL LEUKEMIA-VIRUS TYPE-I TAX MASKS C-MYC FUNCTION THROUGH ACAMP-DEPENDENT PATHWAY
Authors: SEMMES OJ BARRETT JF DANG CV JEANG KT
Citation: Oj. Semmes et al., HUMAN T-CELL LEUKEMIA-VIRUS TYPE-I TAX MASKS C-MYC FUNCTION THROUGH ACAMP-DEPENDENT PATHWAY, The Journal of biological chemistry, 271(16), 1996, pp. 9730-9738
A LINK BETWEEN INCREASED TRANSFORMING ACTIVITY OF LYMPHOMA-DERIVED MYC MUTANT ALLELES, THEIR DEFECTIVE REGULATION BY P107, AND ALTERED PHOSPHORYLATION OF THE C-MYC TRANSACTIVATION DOMAIN
Authors: HOANG AT LUTTERBACH B LEWIS BC YANO T CHOU TY BARRETT JF RAFFELD M HANN SR DANG CV
Citation: At. Hoang et al., A LINK BETWEEN INCREASED TRANSFORMING ACTIVITY OF LYMPHOMA-DERIVED MYC MUTANT ALLELES, THEIR DEFECTIVE REGULATION BY P107, AND ALTERED PHOSPHORYLATION OF THE C-MYC TRANSACTIVATION DOMAIN, Molecular and cellular biology, 15(8), 1995, pp. 4031-4042
SYNTHESIS OF THE DIAZA ANALOG OF ELLAGIC ACID
Authors: KANOJIA RM OHEMENG KA SCHWENDER CF BARRETT JF
Citation: Rm. Kanojia et al., SYNTHESIS OF THE DIAZA ANALOG OF ELLAGIC ACID, Tetrahedron letters, 36(47), 1995, pp. 8553-8556
CYCLIN-A LINKS C-MYC TO ADHESION-INDEPENDENT CELL-PROLIFERATION
Authors: BARRETT JF LEWIS BC HOANG AT ALVAREZ RJ DANG CV
Citation: Jf. Barrett et al., CYCLIN-A LINKS C-MYC TO ADHESION-INDEPENDENT CELL-PROLIFERATION, The Journal of biological chemistry, 270(27), 1995, pp. 15923-15925
PARTICIPATION OF CYCLIN-A IN MYC-INDUCED APOPTOSIS
Authors: HOANG AT COHEN KJ BARRETT JF BERGSTROM DA DANG CV
Citation: At. Hoang et al., PARTICIPATION OF CYCLIN-A IN MYC-INDUCED APOPTOSIS, Proceedings of the National Academy of Sciences of the United Statesof America, 91(15), 1994, pp. 6875-6879
DESIGN AND SYNTHESIS OF ELLIPTICINIUM SALTS AND 1,2-DIHYDROELLIPTICINES WITH HIGH SELECTIVITIES AGAINST HUMAN CNS CANCERS IN-VITRO
Authors: JURAYJ J HAUGWITZ RD VARMA RK PAULL KD BARRETT JF CUSHMAN M
Citation: J. Jurayj et al., DESIGN AND SYNTHESIS OF ELLIPTICINIUM SALTS AND 1,2-DIHYDROELLIPTICINES WITH HIGH SELECTIVITIES AGAINST HUMAN CNS CANCERS IN-VITRO, Journal of medicinal chemistry, 37(14), 1994, pp. 2190-2197
INCREASED TRANSFORMING ACTIVITY OF LYMPHOMA-DERIVED MYC MUTANT ALLELES RESULTS FROM DEFECTIVE REGULATION BY THE GROWTH SUPPRESSOR P107 AND ALTERED PHOSPHORYLATION OF THE MYC TRANSACTIVATION DOMAIN
Authors: HOANG AT LEWIS BC LUTTERBACH B YANO T CHOU TY BARRETT JF RAFFELD M HANN SR DANG CV
Citation: At. Hoang et al., INCREASED TRANSFORMING ACTIVITY OF LYMPHOMA-DERIVED MYC MUTANT ALLELES RESULTS FROM DEFECTIVE REGULATION BY THE GROWTH SUPPRESSOR P107 AND ALTERED PHOSPHORYLATION OF THE MYC TRANSACTIVATION DOMAIN, Blood, 84(10), 1994, pp. 10000038-10000038
CYCLIN-A MEDIATES C-MYC INDUCED APOPTOSIS THAT IS ABROGATED BY BCL-2 WITH ALTERED G1 CYCLINS MESSENGER-RNA EXPRESSION
Authors: HOANG AT COHEN KJ BARRETT JF BERGSTROM DA DANG CV
Citation: At. Hoang et al., CYCLIN-A MEDIATES C-MYC INDUCED APOPTOSIS THAT IS ABROGATED BY BCL-2 WITH ALTERED G1 CYCLINS MESSENGER-RNA EXPRESSION, Blood, 82(10), 1993, pp. 10000441-10000441
TESTING POTENTIAL GYRASE INHIBITORS OF BACTERIAL-DNA GYRASE - A COMPARISON OF THE SUPERCOILING INHIBITION ASSAY AND CLEAVABLE COMPLEX ASSAY
Authors: BARRETT JF BERNSTEIN JI KRAUSE HM HILLIARD JJ OHEMENG KA
Citation: Jf. Barrett et al., TESTING POTENTIAL GYRASE INHIBITORS OF BACTERIAL-DNA GYRASE - A COMPARISON OF THE SUPERCOILING INHIBITION ASSAY AND CLEAVABLE COMPLEX ASSAY, Analytical biochemistry, 214(1), 1993, pp. 313-317
Risultati: 1-25 |