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Results: 1-25/28
Authors:
Prhavc, M
Bhat, B
Just, G
Cook, PD
Manoharan, M
Citation: M. Prhavc et al., Chimeric RNA with modified backbones: Alternating methylene(methylimino) linked phosphodiester backbone oligonucleotides with 2 '-OH and 2 '-OME groups, NUCLEOS NUC, 20(4-7), 2001, pp. 995-997
Authors:
An, HY
Wang, TM
Maier, MA
Manoharan, M
Ross, BS
Cook, PD
Citation: Hy. An et al., Synthesis of novel 3 '-C-methylene thymidine and 5-methyluridine/cytidine H-phosphonates and phosphonamidites for new backbone modification of oligonucleotides, J ORG CHEM, 66(8), 2001, pp. 2789-2801
Authors:
Cook, PD
Citation: Pd. Cook, Medicinal chemistry of antisense oligonucleotides, ANTISENSE DRUG TECHNOLOGY: PRINCIPLES, STRATEGIES, AND APPLICATIONS, 2001, pp. 29-56
Authors:
Kertesz, V
Whittemore, NA
Inamati, GB
Manoharan, M
Cook, PD
Baker, DC
Chambers, JQ
Citation: V. Kertesz et al., Electrochemical detection of surface hybridization of oligodeoxynucleotides bearing anthraquinone tags at gold electrodes, ELECTROANAL, 12(12), 2000, pp. 889-894
Authors:
Filikov, AV
Mohan, V
Vickers, TA
Griffey, RH
Cook, PD
Abagyan, RA
James, TL
Citation: Av. Filikov et al., Identification of ligands for RNA targets via structure-based virtual screening: HIV-1 TAR, J COMPUT A, 14(6), 2000, pp. 593-610
Authors:
Prhavc, M
Just, G
Bhat, B
Cook, PD
Manoharan, M
Citation: M. Prhavc et al., A new approach for the synthesis of 3 '-deoxy-3 '-C-formyl-ribonucleosidesand the synthesis of alternating methylene(methylimino) linked phosphodiester backbone oligonucleotides with 2 '-OH and 2 '-OMe groups, TETRAHEDR L, 41(51), 2000, pp. 9967-9971
Authors:
An, HY
Wang, TM
Cook, PD
Citation: Hy. An et al., Synthesis of novel 3 '-methylene H-phosphonate thymidines, TETRAHEDR L, 41(41), 2000, pp. 7813-7816
Authors:
Wang, TM
An, HY
Haly, BD
Cook, PD
Citation: Tm. Wang et al., Synthesis of polyazacyclophane-intercalator conjugates for combinatorial chemistry and RNA interaction studies, J HETERO CH, 37(4), 2000, pp. 687-696
Authors:
An, HY
Cook, PD
Citation: Hy. An et Pd. Cook, Methodologies for generating solution-phase combinatorial libraries, CHEM REV, 100(9), 2000, pp. 3311-3340
Authors:
Bennett, CF
Butler, M
Cook, PD
Geary, RS
Levin, AA
Mehta, R
Teng, CL
Deshmukh, H
Tillman, L
Hardee, G
Citation: Cf. Bennett et al., Antisense oligonucleotide-based therapeutics, GENE THERAPY, 2000, pp. 305-332
Authors:
Manoharan, M
Andrade, LK
Cook, PD
Citation: M. Manoharan et al., Site-specific cross-linking of nucleic acids using the abasic site, ORG LETT, 1(2), 1999, pp. 311-314
Authors:
Teplova, M
Minasov, G
Tereshko, V
Inamati, GB
Cook, PD
Manoharan, M
Egli, M
Citation: M. Teplova et al., Crystal structure and improved antisense properties of 2 '-O-(2-methoxyethyl)-RNA, NAT ST BIOL, 6(6), 1999, pp. 535-539
Authors:
Whittemore, NA
Mullenix, AN
Inamati, GB
Manoharan, M
Cook, PD
Tuinman, AA
Baker, DC
Chambers, JQ
Citation: Na. Whittemore et al., Synthesis and electrochemistry of anthraquinone-oligodeoxynucleotide conjugates, BIOCONJ CHE, 10(2), 1999, pp. 261-270
Authors:
Cook, PD
Citation: Pd. Cook, Making drugs out of oligonucleotides: A brief review and perspective, NUCLEOS NUC, 18(6-7), 1999, pp. 1141-1162
Authors:
Manoharan, M
Prakash, TP
Barber-Peoc'h, I
Bhat, B
Vasquez, G
Ross, BS
Cook, PD
Citation: M. Manoharan et al., A new protecting group strategy for amino groups in oligonucleotide chemistry: CEOC group, NUCLEOS NUC, 18(6-7), 1999, pp. 1199-1201
Authors:
Prakash, TP
Kawasaki, AM
Vasquez, G
Fraser, AS
Casper, MD
Cook, PD
Manoharan, M
Citation: Tp. Prakash et al., 2 '-DMAOE RNA: Emerging oligonucleotides with promising antisense properties, NUCLEOS NUC, 18(6-7), 1999, pp. 1381-1382
Authors:
Cowsert, LM
Ohashi, CT
Bhat, B
Peoc'h, D
Symons, AM
Cook, PD
Manoharan, M
Citation: Lm. Cowsert et al., MMI linkage modification increases potency and stability of H-ras antisense oligonucleotides, NUCLEOS NUC, 18(6-7), 1999, pp. 1383-1384
Authors:
Kawasaki, AM
Casper, MD
Prakash, TP
Manalili, S
Sasmor, H
Manoharan, M
Cook, PD
Citation: Am. Kawasaki et al., Synthesis, hybridization, and nuclease resistance properties of 2 '-O-aminooxyethyl modified oligonucleotides, NUCLEOS NUC, 18(6-7), 1999, pp. 1419-1420
Authors:
Bhat, B
Balow, G
Guzaev, A
Cook, PD
Manoharan, M
Citation: B. Bhat et al., Synthesis of fully protected nucleoside-folic acid conjugated phosphoramidites and their incorporation into antisense oligonuleotides, NUCLEOS NUC, 18(6-7), 1999, pp. 1471-1472
Authors:
Manoharan, M
Kawasaki, AM
Prakash, TP
Fraser, AS
Prhavc, M
Inamati, GB
Casper, MD
Cook, PD
Citation: M. Manoharan et al., Carbohydrate modifications in antisense oligonucleotide therapy: New kids on the block, NUCLEOS NUC, 18(6-7), 1999, pp. 1737-1746
Authors:
Kawasaki, AM
Casper, MD
Gaus, HJ
Herrmann, R
Griffey, RH
Cook, PD
Citation: Am. Kawasaki et al., Solution phase combinatorial chemistry. Purine- and pyrimidine-based libraries with antibacterial activity via solution phase simultaneous addition of functionalities, NUCLEOS NUC, 18(4-5), 1999, pp. 659-660
Authors:
Fraser, AS
Kawasaki, AM
Cook, PD
Citation: As. Fraser et al., Purine based combinatorial chemistry: Solution phase simultaneous additionof functionalities. Iterative deconvolution by orthogonal protection to a single compound with potent antibacterial activity., NUCLEOS NUC, 18(4-5), 1999, pp. 1087-1089
Authors:
Kawasaki, AM
Casper, MD
Prakash, TP
Manalili, S
Sasmor, H
Manoharan, M
Cook, PD
Citation: Am. Kawasaki et al., Synthesis, hybridization, and nuclease resistance properties of 2 '-O-aminooxyethyl (2 '-O-AOE) modified oligonucleotides, TETRAHEDR L, 40(4), 1999, pp. 661-664
Authors:
Teplova, M
Wallace, ST
Tereshko, V
Minasov, G
Symons, AM
Cook, PD
Manoharan, M
Egli, M
Citation: M. Teplova et al., Structural origins of the exonuclease resistance of a zwitterionic RNA, P NAS US, 96(25), 1999, pp. 14240-14245
Authors:
Manoharan, M
Prakash, TP
Barber-Peoc'h, I
Bhat, B
Vasquez, G
Ross, BS
Cook, PD
Citation: M. Manoharan et al., N-(2-cyanoethoxycarbonyloxy) succinimide: A new reagent for protection of amino groups in oligonucleotides, J ORG CHEM, 64(17), 1999, pp. 6468-6472