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Synthesis of the tBuSATE pronucleotide of AZT by two different synthetic approaches
Authors: Lannuzel, M Egron, D Imbach, JL Gosselin, G Perigaud, C
Citation: M. Lannuzel et al., Synthesis of the tBuSATE pronucleotide of AZT by two different synthetic approaches, NUCLEOS NUC, 18(4-5), 1999, pp. 1001-1002
Synthesis of new PMEA diphosphate mimics
Authors: Laux, WHG Perigaud, C Imbach, JL Gosselin, G
Citation: Whg. Laux et al., Synthesis of new PMEA diphosphate mimics, NUCLEOS NUC, 18(4-5), 1999, pp. 1003-1004
Comparison of anti-HBV activity of beta-D- and beta-L-DDA-5 ' monophosphate prodrugs and effectiveness in combination with lamivudine.
Authors: Loi, AG Faraj, A Pierra, C Gosselin, G Imbach, JL Locarnini, SA Groman, EV Schinazi, RF Sommadossi, JP
Citation: Ag. Loi et al., Comparison of anti-HBV activity of beta-D- and beta-L-DDA-5 ' monophosphate prodrugs and effectiveness in combination with lamivudine., NUCLEOS NUC, 18(4-5), 1999, pp. 1005-1006
New series of mixed pronucleotides. Synthesis and anti-HIV activities of mononucleoside phenyl SATE phosphotriesters
Authors: Schlienger, N Peyrottes, S Aubertin, AM Gosselin, G Imbach, JL Perigaud, C
Citation: N. Schlienger et al., New series of mixed pronucleotides. Synthesis and anti-HIV activities of mononucleoside phenyl SATE phosphotriesters, NUCLEOS NUC, 18(4-5), 1999, pp. 1025-1026
Proceedings of the XIII International Round Table - Preface
Authors: Gosselin, G
Citation: G. Gosselin, Proceedings of the XIII International Round Table - Preface, NUCLEOS NUC, 18(4-5), 1999, pp. XXXIX-XL
Synthesis and biological evaluation of 9-(beta-L-arabinofuranosyl)adenine
Authors: Boudou, V Imbach, JL Gosselin, G
Citation: V. Boudou et al., Synthesis and biological evaluation of 9-(beta-L-arabinofuranosyl)adenine, NUCLEOS NUC, 18(11-12), 1999, pp. 2463-2473
Synthesis and anti-retroviral activity of O,O '-bis(3 '-azido-2 ',3 '-dideoxythymidin-5 '-yl) phosphoramidate derivatives
Authors: Kers, I Stawinski, J Girardet, JL Imbach, JL Perigaud, C Gosselin, G Aubertin, AM
Citation: I. Kers et al., Synthesis and anti-retroviral activity of O,O '-bis(3 '-azido-2 ',3 '-dideoxythymidin-5 '-yl) phosphoramidate derivatives, NUCLEOS NUC, 18(10), 1999, pp. 2317-2325
Richard P. Goldthwait
Authors: Gosselin, G
Citation: G. Gosselin, Richard P. Goldthwait, GEOGR PHYS, 53(1), 1999, pp. 5-6
Molecular basis for the enantioselectivity of HIV-1 reverse transcriptase:role of the 3 '-hydroxyl group of the L-(beta)-ribose in chiral discrimination between D- and L-enantiomers of deoxy- and dideoxy-nucleoside triphosphate analogs
Authors: Maga, G Amacker, M Hubscher, U Gosselin, G Imbach, JL Mathe, C Faraj, A Sommadossi, JP Spadari, S
Citation: G. Maga et al., Molecular basis for the enantioselectivity of HIV-1 reverse transcriptase:role of the 3 '-hydroxyl group of the L-(beta)-ribose in chiral discrimination between D- and L-enantiomers of deoxy- and dideoxy-nucleoside triphosphate analogs, NUCL ACID R, 27(4), 1999, pp. 972-978
Stereospecific synthesis of unnatural beta-L-enantiomers of 2-chloroadenine pentofuranonucleoside derivatives
Authors: Marchand, A Lioux, T Mathe, C Imbach, JL Gosselin, G
Citation: A. Marchand et al., Stereospecific synthesis of unnatural beta-L-enantiomers of 2-chloroadenine pentofuranonucleoside derivatives, J CHEM S P1, (16), 1999, pp. 2249-2254
Low enantioselectivities of human deoxycytidine kinase and human deoxyguanosine kinase with respect to 2 '-deoxyadenosine, 2 '-deoxyguanosine and their analogs
Authors: Gaubert, G Gosselin, G Boudou, V Imbach, JL Eriksson, S Maury, G
Citation: G. Gaubert et al., Low enantioselectivities of human deoxycytidine kinase and human deoxyguanosine kinase with respect to 2 '-deoxyadenosine, 2 '-deoxyguanosine and their analogs, BIOCHIMIE, 81(11), 1999, pp. 1041-1047
L-ATP is recognized by some cellular and viral enzymes: does chance drive enzymic enantioselectivity?
Authors: Verri, A Montecucco, A Gosselin, G Boudou, V Imbach, JL Spadari, S Focher, F
Citation: A. Verri et al., L-ATP is recognized by some cellular and viral enzymes: does chance drive enzymic enantioselectivity?, BIOCHEM J, 337, 1999, pp. 585-590
Study of human deoxycytidine kinase binding properties using intrinsic fluorescence or new fluorescent ligands
Authors: Shafiee, M Gosselin, G Imbach, JL Divita, G Eriksson, S Maury, G
Citation: M. Shafiee et al., Study of human deoxycytidine kinase binding properties using intrinsic fluorescence or new fluorescent ligands, EUR J MED C, 34(5), 1999, pp. 423-431
The S-acyl-2-thioethyl pronucleotide approach applied to acyclovir - Part I. Synthesis and in vitro anti-hepatitis B virus activity of bis(S-acyl-2-thioethyl)phosphotriester derivatives of acyclovir
Authors: Perigaud, C Gosselin, G Girardet, JL Korba, BE Imbach, JL
Citation: C. Perigaud et al., The S-acyl-2-thioethyl pronucleotide approach applied to acyclovir - Part I. Synthesis and in vitro anti-hepatitis B virus activity of bis(S-acyl-2-thioethyl)phosphotriester derivatives of acyclovir, ANTIVIR RES, 40(3), 1999, pp. 167-178
The SATE pronucleotide approach applied to acyclovir - Part II. Effects ofbis(SATE)phosphotriester derivatives of acyclovir on duck hepatitis B virus replication in vitro and in vivo
Authors: Hantz, O Perigaud, C Borel, C Jamard, C Zoulim, F Trepo, C Imbach, JL Gosselin, G
Citation: O. Hantz et al., The SATE pronucleotide approach applied to acyclovir - Part II. Effects ofbis(SATE)phosphotriester derivatives of acyclovir on duck hepatitis B virus replication in vitro and in vivo, ANTIVIR RES, 40(3), 1999, pp. 179-187
Pharmacokinetics of beta-L-2 ',3 '-dideoxy-5-fluorocytidine in rhesus monkeys
Authors: Martin, LT Cretton-Scott, E Schinazi, RF Zhou, XJ McClure, HM Mathe, C Gosselin, G Imbach, JL Sommadossi, JP
Citation: Lt. Martin et al., Pharmacokinetics of beta-L-2 ',3 '-dideoxy-5-fluorocytidine in rhesus monkeys, ANTIM AG CH, 43(4), 1999, pp. 920-924
Two-metal-ion catalysis in adenylyl cyclase
Authors: Tesmer, JJG Sunahara, RK Johnson, RA Gosselin, G Gilman, AG Sprang, SR
Citation: Jjg. Tesmer et al., Two-metal-ion catalysis in adenylyl cyclase, SCIENCE, 285(5428), 1999, pp. 756-760
Enzymatic synthesis of unlabeled and beta-P-32-labeled beta-L-2 ',3 '-dideoxyadenosine-5 '-triphosphate as a potent inhibitor of adenylyl cyclases and its use as reversible binding ligand
Authors: Shoshani, I Boudou, V Pierra, C Gosselin, G Johnson, RA
Citation: I. Shoshani et al., Enzymatic synthesis of unlabeled and beta-P-32-labeled beta-L-2 ',3 '-dideoxyadenosine-5 '-triphosphate as a potent inhibitor of adenylyl cyclases and its use as reversible binding ligand, J BIOL CHEM, 274(49), 1999, pp. 34735-34741
Inhibition of adenylyl cyclase by acyclic nucleoside phosphonate antiviralagents
Authors: Shoshani, I Laux, WHG Perigaud, C Gosselin, G Johnson, RA
Citation: I. Shoshani et al., Inhibition of adenylyl cyclase by acyclic nucleoside phosphonate antiviralagents, J BIOL CHEM, 274(49), 1999, pp. 34742-34744
2-(glucosylthio)ethyl groups as potential biolabile phosphate-protecting groups of mononucleotides
Authors: Schlienger, N Perigaud, C Aubertin, AM Thumann, C Gosselin, G Imbach, JL
Citation: N. Schlienger et al., 2-(glucosylthio)ethyl groups as potential biolabile phosphate-protecting groups of mononucleotides, HELV CHIM A, 82(11), 1999, pp. 2044-2051
Effects of probucol on vascular remodeling after coronary angioplasty
Authors: Cote, G Tardif, JC Lesperance, J Lambert, J Bourassa, M Bonan, R Gosselin, G Joyal, M Tanguay, JF Nattel, S Gallo, R Crepeau, J
Citation: G. Cote et al., Effects of probucol on vascular remodeling after coronary angioplasty, CIRCULATION, 99(1), 1999, pp. 30-35
A rational strategy for the design of anti-hepatitis B virus nucleotide derivatives
Authors: Perigaud, C Gosselin, G Imbach, JL
Citation: C. Perigaud et al., A rational strategy for the design of anti-hepatitis B virus nucleotide derivatives, THERAPIES FOR VIRAL HEPATITIS, 1998, pp. 313-319
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