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Results: 1-19 |
Results: 19
INHIBITION OF STROMELYSIN-1 (MMP-3) BY P-1'-BIPHENYLYLETHYL CARBOXYALKYL DIPEPTIDES
Authors: ESSER CK BUGIANESI RL CALDWELL CG CHAPMAN KT DURETTE PL GIROTRA NN KOPKA IE LANZA TJ LEVORSE DA MACCROSS M OWENS KA PONPIPOM MM SIMEONE JP HARRISON RK NIEDZWIECKI L BECKER JW MARCY AI AXEL MG CHRISTEN AJ MCDONNELL J MOORE VL OLSZEWSKI JM SAPHOS C VISCO DM SHEN F COLLETTI A KRIETER PA HAGMANN WK
Citation: Ck. Esser et al., INHIBITION OF STROMELYSIN-1 (MMP-3) BY P-1'-BIPHENYLYLETHYL CARBOXYALKYL DIPEPTIDES, Journal of medicinal chemistry, 40(6), 1997, pp. 1026-1040
ORALLY-ACTIVE INHIBITORS OF STROMELYSIN-1 (MMP-3)
Authors: CHAPMAN KT DURETTE PL CALDWELL CG SPEROW KM NIEDZWIECKI LM HARRISON RK SAPHOS C CHRISTEN AJ OLSZEWSKI JM MOORE VL MACCOSS M HAGMANN WK
Citation: Kt. Chapman et al., ORALLY-ACTIVE INHIBITORS OF STROMELYSIN-1 (MMP-3), Bioorganic & medicinal chemistry letters, 6(7), 1996, pp. 803-806
PHOSPHINIC ACID INHIBITORS OF MATRIX METALLOPROTEINASES
Authors: CALDWELL CG SAHOO SP POLO SA EVERSOLE RR LANZA TJ MILLS SG NIEDZWIECKI LM IZQUIERDOMARTIN M CHANG BC HARRISON RK KUO DW LIN TY STEIN RL DURETTE PL HAGMANN WK
Citation: Cg. Caldwell et al., PHOSPHINIC ACID INHIBITORS OF MATRIX METALLOPROTEINASES, Bioorganic & medicinal chemistry letters, 6(3), 1996, pp. 323-328
INHIBITION OF MATRIX METALLOPROTEINASES BY P-1 SUBSTITUTED N-CARBOXYALKYL DIPEPTIDES
Authors: CHAPMAN KT WALES J SAHOO SP NIEDZWIECKI LM IZQUIERDOMARTIN M CHANG BC HARRISON RK STEIN RL HAGMANN WK
Citation: Kt. Chapman et al., INHIBITION OF MATRIX METALLOPROTEINASES BY P-1 SUBSTITUTED N-CARBOXYALKYL DIPEPTIDES, Bioorganic & medicinal chemistry letters, 6(3), 1996, pp. 329-332
COMPARISON OF THE STRUCTURE OF HUMAN RECOMBINANT SHORT-FORM STROMELYSIN BY MULTIDIMENSIONAL HETERONUCLEAR NMR AND X-RAY CRYSTALLOGRAPHY
Authors: GOOLEY PR OCONNELL JF MARCY AI CUCA GC AXEL MG CALDWELL CG HAGMANN WK BECKER JW
Citation: Pr. Gooley et al., COMPARISON OF THE STRUCTURE OF HUMAN RECOMBINANT SHORT-FORM STROMELYSIN BY MULTIDIMENSIONAL HETERONUCLEAR NMR AND X-RAY CRYSTALLOGRAPHY, Journal of biomolecular NMR, 7(1), 1996, pp. 8-28
PROTEOGLYCAN-DEGRADING ACTIVITY OF HUMAN STROMELYSIN-1 AND LEUKOCYTE ELASTASE IN RABBIT JOINTS - QUANTITATION OF PROTEOGLYCAN AND A STROMELYSIN-INDUCED HABR FRAGMENT OF AGGRECAN IN SYNOVIAL-FLUID AND CARTILAGE
Authors: OLSZEWSKI JM MOORE VL MCDONNELL J WILLIAMS H SAPHOS CA GREEN BG KNIGHT WB CHAPMAN KT HAGMANN WK DORN CP HALE JJ MUMFORD RA
Citation: Jm. Olszewski et al., PROTEOGLYCAN-DEGRADING ACTIVITY OF HUMAN STROMELYSIN-1 AND LEUKOCYTE ELASTASE IN RABBIT JOINTS - QUANTITATION OF PROTEOGLYCAN AND A STROMELYSIN-INDUCED HABR FRAGMENT OF AGGRECAN IN SYNOVIAL-FLUID AND CARTILAGE, Connective tissue research, 33(4), 1996, pp. 291-299
STROMELYSIN-1 - 3-DIMENSIONAL STRUCTURE OF THE INHIBITED CATALYTIC DOMAIN AND OF THE C-TRUNCATED PROENZYME
Authors: BECKER JW MARCY AI ROKOSZ LL AXEL MG BURBAUM JJ FITZGERALD PMD CAMERON PM ESSER CK HAGMANN WK HERMES JD SPRINGER JP
Citation: Jw. Becker et al., STROMELYSIN-1 - 3-DIMENSIONAL STRUCTURE OF THE INHIBITED CATALYTIC DOMAIN AND OF THE C-TRUNCATED PROENZYME, Protein science, 4(10), 1995, pp. 1966-1976
INHIBITION OF MATRIX METALLOPROTEINASES BY N-CARBOXYALKYL PEPTIDES CONTAINING EXTENDED ALKYL RESIDUES AT P-1
Authors: ESSER CK KOPKA IE DURETTE PL HARRISON RK NIEDZWIECKI LM IZQUIERDOMARTIN M STEIN RL HAGMANN WK
Citation: Ck. Esser et al., INHIBITION OF MATRIX METALLOPROTEINASES BY N-CARBOXYALKYL PEPTIDES CONTAINING EXTENDED ALKYL RESIDUES AT P-1, Bioorganic & medicinal chemistry letters, 5(6), 1995, pp. 539-542
INHIBITION OF MATRIX METALLOPROTEINASES BY N-CARBOXYALKYL DIPEPTIDES - ENHANCED POTENCY AND SELECTIVITY WITH SUBSTITUTED P-1' HOMOPHENYLALANINES
Authors: SAHOO SP CALDWELL CG CHAPMAN KT DURETTE PL ESSER CK KOPKA IE POLO SA SPEROW KM NIEDZWIECKI LM IZQUIERDOMARTIN M CHANG BC HARRISON RK STEIN RL MACCOSS M HAGMANN WK
Citation: Sp. Sahoo et al., INHIBITION OF MATRIX METALLOPROTEINASES BY N-CARBOXYALKYL DIPEPTIDES - ENHANCED POTENCY AND SELECTIVITY WITH SUBSTITUTED P-1' HOMOPHENYLALANINES, Bioorganic & medicinal chemistry letters, 5(20), 1995, pp. 2441-2446
INHIBITION OF INTERLEUKIN-1-BETA CONVERTING-ENZYME BY N-ACYL-ASPARTYLARYLOXYMETHYL KETONES
Authors: MJALLI AMM ZHAO JJ CHAPMAN KT THORNBERRY NA PETERSON EP MACCOSS M HAGMANN WK
Citation: Amm. Mjalli et al., INHIBITION OF INTERLEUKIN-1-BETA CONVERTING-ENZYME BY N-ACYL-ASPARTYLARYLOXYMETHYL KETONES, Bioorganic & medicinal chemistry letters, 5(13), 1995, pp. 1409-1414
4-AZASTEROIDS AS 5-ALPHA-REDUCTASE INHIBITORS - IDENTIFICATION OF 4,7-BETA-DIMETHYL-4-AZA-5-ALPHA-CHOLESTAN-3-ONE (MK-386) AS A SCALP ISOZYME-SELECTIVE INHIBITOR
Authors: TOLMAN RL ASTER S BAKSHI RK BERGMAN JP BULL HG CHANG B CIMIS G DOLENGA MP DURETTE P ELLSWORTH K ESSER C GRAHAM DW HAGMANN WK HARRIS G KOPKA I LANZA T PATEL G POLO S RASMUSSON GH SAHOO S TONEY JH VONLANGEN D WITZEL B
Citation: Rl. Tolman et al., 4-AZASTEROIDS AS 5-ALPHA-REDUCTASE INHIBITORS - IDENTIFICATION OF 4,7-BETA-DIMETHYL-4-AZA-5-ALPHA-CHOLESTAN-3-ONE (MK-386) AS A SCALP ISOZYME-SELECTIVE INHIBITOR, European journal of medicinal chemistry, 30, 1995, pp. 311-316
MECHANISM OF INHIBITION OF HUMAN-LEUKOCYTE ELASTASE BY BETA-LACTAMS .2. STABILITY, REACTIVATION KINETICS, AND PRODUCTS OF BETA-LACTAM-DERIVED E-I COMPLEXES
Authors: GREEN BG CHABIN R MILLS S UNDERWOOD DJ SHAH SK KUO D GALE P MAYCOCK AL LIESCH J BURGEY CS DOHERTY JB DORN CP FINKE PE HAGMANN WK HALE JJ MACCOSS M WESTLER WM KNIGHT WB
Citation: Bg. Green et al., MECHANISM OF INHIBITION OF HUMAN-LEUKOCYTE ELASTASE BY BETA-LACTAMS .2. STABILITY, REACTIVATION KINETICS, AND PRODUCTS OF BETA-LACTAM-DERIVED E-I COMPLEXES, Biochemistry, 34(44), 1995, pp. 14331-14343
THE NMR STRUCTURE OF THE INHIBITED CATALYTIC DOMAIN OF HUMAN STROMELYSIN-1
Authors: GOOLEY PR OCONNELL JF MARCY AI CUCA GC SALOWE SP BUSH BL HERMES JD ESSER CK HAGMANN WK SPRINGER JP JOHNSON BA
Citation: Pr. Gooley et al., THE NMR STRUCTURE OF THE INHIBITED CATALYTIC DOMAIN OF HUMAN STROMELYSIN-1, Nature structural biology, 1(2), 1994, pp. 111-118
INHIBITION OF STROMELYSIN-1 (MMP-3) BY PEPTIDYL PHOSPHINIC ACIDS
Authors: GOULET JL KINNEARY JF DURETTE PL STEIN RL HARRISON RK IZQUIERDOMARTIN M KUO DW LIN TY HAGMANN WK
Citation: Jl. Goulet et al., INHIBITION OF STROMELYSIN-1 (MMP-3) BY PEPTIDYL PHOSPHINIC ACIDS, Bioorganic & medicinal chemistry letters, 4(10), 1994, pp. 1221-1224
STUDIES ON THE KINETIC AND CHEMICAL MECHANISM OF INHIBITION OF STROMELYSIN BY AN N-(CARBOXYALKYL)DIPEPTIDE
Authors: IZQUIERDOMARTIN M CHAPMAN KT HAGMANN WK STEIN RL
Citation: M. Izquierdomartin et al., STUDIES ON THE KINETIC AND CHEMICAL MECHANISM OF INHIBITION OF STROMELYSIN BY AN N-(CARBOXYALKYL)DIPEPTIDE, Biochemistry, 33(6), 1994, pp. 1356-1365
CHEMICAL, BIOCHEMICAL, PHARMACOKINETIC, AND BIOLOGICAL PROPERTIES OF L-680,833 - A POTENT, ORALLY-ACTIVE MONOCYCLIC BETA-LACTAM INHIBITOR OF HUMAN POLYMORPHONUCLEAR LEUKOCYTE ELASTASE
Authors: DOHERTY JB SHAH SK FINKE PE DORN CP HAGMANN WK HALE JJ KISSINGER AL THOMPSON KR BRAUSE K CHANDLER GO KNIGHT WB MAYCOCK AL AHSE BM WESTON H GALE P MUMFORD RA ANDERSEN OF WILLIAMS HR NOLAN TE FRANKENFIELD DL UNDERWOOD D VYAS KP KARI PH DAHLGREN ME MAO J FLETCHER DS DELLEA PS HAND KM OSINGA DG PETERSON LB WILLIAMS DT METZGER JM BONNEY RJ HUMES JL PACHOLOK SP HANLON WA OPAS E STOLK J DAVIES P
Citation: Jb. Doherty et al., CHEMICAL, BIOCHEMICAL, PHARMACOKINETIC, AND BIOLOGICAL PROPERTIES OF L-680,833 - A POTENT, ORALLY-ACTIVE MONOCYCLIC BETA-LACTAM INHIBITOR OF HUMAN POLYMORPHONUCLEAR LEUKOCYTE ELASTASE, Proceedings of the National Academy of Sciences of the United Statesof America, 90(18), 1993, pp. 8727-8731
INHIBITION OF MATRIX METALLOPROTEINASES BY N-CARBOXYALKYL PEPTIDES
Authors: CHAPMAN KT KOPKA IE DURETTE PL ESSER CK LANZA TJ IZQUIERDOMARTIN M NIEDZWIECKI L CHANG B HARRISON RK KUO DW LIN TY STEIN RL HAGMANN WK
Citation: Kt. Chapman et al., INHIBITION OF MATRIX METALLOPROTEINASES BY N-CARBOXYALKYL PEPTIDES, Journal of medicinal chemistry, 36(26), 1993, pp. 4293-4301
SECONDARY STRUCTURE AND ZINC LIGATION OF HUMAN RECOMBINANT SHORT-FORMSTROMELYSIN BY MULTIDIMENSIONAL HETERONUCLEAR NMR
Authors: GOOLEY PR JOHNSON BA MARCY AI CUCA GC SALOWE SP HAGMANN WK ESSER CK SPRINGER JP
Citation: Pr. Gooley et al., SECONDARY STRUCTURE AND ZINC LIGATION OF HUMAN RECOMBINANT SHORT-FORMSTROMELYSIN BY MULTIDIMENSIONAL HETERONUCLEAR NMR, Biochemistry, 32(48), 1993, pp. 13098-13108
MECHANISM OF INHIBITION OF HUMAN-LEUKOCYTE ELASTASE BY MONOCYCLIC BETA-LACTAMS
Authors: CHABIN R GREEN BG GALE P MAYCOCK AL WESTON H DORN CP FINKE PE HAGMANN WK HALE JJ MACCOSS M SHAH SK UNDERWOOD D DOHERTY JB KNIGHT WB
Citation: R. Chabin et al., MECHANISM OF INHIBITION OF HUMAN-LEUKOCYTE ELASTASE BY MONOCYCLIC BETA-LACTAMS, Biochemistry, 32(34), 1993, pp. 8970-8980
Risultati: 1-19 |