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Results: 1-15 |
Results: 15
Crystal structure of Staphylococcus aureus tyrosyl-tRNA synthetase in complex with a class of potent and specific inhibitors
Authors: Qiu, XY Janson, CA Smith, WW Green, SM McDevitt, P Johanson, K Carter, P Hibbs, M Lewis, C Chalker, A Fosberry, A Lalonde, J Berge, J Brown, P Houge-Frydrych, CSV Jarvest, RL
Citation: Xy. Qiu et al., Crystal structure of Staphylococcus aureus tyrosyl-tRNA synthetase in complex with a class of potent and specific inhibitors, PROTEIN SCI, 10(10), 2001, pp. 2008-2016
Inhibitors of bacterial enoyl acyl carrier protein reductase (FabI): 2,9-disubstituted 1,2,3,4-tetrahydropyrido[3,4-b]indoles as potential antibacterial agents
Authors: Seefeld, MA Miller, WH Newlander, KA Burgess, WJ Payne, DJ Rittenhouse, SF Moore, TD DeWolf, WE Keller, PM Qiu, XY Janson, CA Vaidya, K Fosberry, AP Smyth, MG Jaworski, DD Slater-Radosti, C Huffman, WF
Citation: Ma. Seefeld et al., Inhibitors of bacterial enoyl acyl carrier protein reductase (FabI): 2,9-disubstituted 1,2,3,4-tetrahydropyrido[3,4-b]indoles as potential antibacterial agents, BIOORG MED, 11(17), 2001, pp. 2241-2244
1,4-disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI)
Authors: Heerding, DA Chan, G DeWolf, WE Fosberry, AP Janson, CA Jaworski, DD McManus, E Miller, WH Moore, TD Payne, DJ Qiu, XY Rittenhouse, SF Slater-Radosti, C Smith, W Takata, DT Vaidya, KS Yuan, CCK Huffman, WF
Citation: Da. Heerding et al., 1,4-disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI), BIOORG MED, 11(16), 2001, pp. 2061-2065
Refined structures of beta-ketoacyl-acyl carrier protein synthase III
Authors: Qiu, XY Janson, CA Smith, WW Head, M Lonsdale, J Konstantinidis, AK
Citation: Xy. Qiu et al., Refined structures of beta-ketoacyl-acyl carrier protein synthase III, J MOL BIOL, 307(1), 2001, pp. 341-356
Azepanone-based inhibitors of human and rat cathepsin K
Authors: Marquis, RW Ru, Y LoCastro, SM Zeng, J Yamashita, DS Oh, HJ Erhard, KF Davis, LD Tomaszek, TA Tew, D Salyers, K Proksch, J Ward, K Smith, B Levy, M Cummings, MD Haltiwanger, RC Trescher, G Wang, B Hemling, ME Quinn, CJ Cheng, HY Lin, F Smith, WW Janson, CA Zhao, BG McQueney, MS D'Alessio, K Lee, CP Marzulli, A Dodds, RA Blake, S Hwang, SM James, IE Gress, CJ Bradley, BR Lark, MW Gowen, M Veber, DF
Citation: Rw. Marquis et al., Azepanone-based inhibitors of human and rat cathepsin K, J MED CHEM, 44(9), 2001, pp. 1380-1395
Cyclic ketone inhibitors of the cysteine protease cathepsin K
Authors: Marquis, RW Ru, Y Zeng, J Trout, REL LoCastro, SM Gribble, AD Witherington, J Fenwick, AE Garnier, B Tomaszek, T Tew, D Hemling, ME Quinn, CJ Smith, WW Zhao, BG McQueney, MS Janson, CA D'Alessio, K Veber, DF
Citation: Rw. Marquis et al., Cyclic ketone inhibitors of the cysteine protease cathepsin K, J MED CHEM, 44(5), 2001, pp. 725-736
Crystallization of Escherichia coli beta-ketoacyl-ACP synthase III and theuse of a dry flash-cooling technique for data collection
Authors: Janson, CA Konstantinidis, AK Lonsdale, JT Qiu, XY
Citation: Ca. Janson et al., Crystallization of Escherichia coli beta-ketoacyl-ACP synthase III and theuse of a dry flash-cooling technique for data collection, ACT CRYST D, 56, 2000, pp. 747-748
Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality
Authors: Lee, D Long, SA Adams, JL Chan, G Vaidya, KS Francis, TA Kikly, K Winkler, JD Sung, CM Debouck, C Richardson, S Levy, MA DeWolf, WE Keller, PM Tomaszek, T Head, MS Ryan, MD Haltiwanger, RC Liang, PH Janson, CA McDevitt, PJ Johanson, K Concha, NO Chan, W Abdel-Meguid, SS Badger, AM Lark, MW Nadeau, DP Suva, LJ Gowen, M Nuttall, ME
Citation: D. Lee et al., Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality, J BIOL CHEM, 275(21), 2000, pp. 16007-16014
Crystal structure of the IMP-1 metallo beta-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor: Binding determinants of a potent, broad-spectrum inhibitor
Authors: Concha, NO Janson, CA Rowling, P Pearson, S Cheever, CA Clarke, BP Lewis, C Galleni, M Frere, JM Payne, DJ Bateson, JH Abdel-Meguid, SS
Citation: No. Concha et al., Crystal structure of the IMP-1 metallo beta-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor: Binding determinants of a potent, broad-spectrum inhibitor, BIOCHEM, 39(15), 2000, pp. 4288-4298
Expression, purification, and crystallization of the Escherichia coli selenomethionyl beta-ketoacyl-acyl carrier protein synthase III
Authors: Khandekar, SS Konstantinidis, AK Silverman, C Janson, CA McNulty, DE Nwagwu, S Van Aller, GS Doyle, ML Kane, JF Qiu, XY Lonsdale, J
Citation: Ss. Khandekar et al., Expression, purification, and crystallization of the Escherichia coli selenomethionyl beta-ketoacyl-acyl carrier protein synthase III, BIOC BIOP R, 270(1), 2000, pp. 100-107
Potent dipeptidylketone inhibitors of the cysteine protease cathepsin K
Authors: Marquis, RW Ru, Y Yamashita, DS Oh, HJ Yen, J Thompson, SK Carr, TJ Levy, MA Tomaszek, TA Ijames, CF Smith, WW Zhao, BG Janson, CA Abdel-Meguid, SS D'Alessio, KJ McQueney, MS Veber, DF
Citation: Rw. Marquis et al., Potent dipeptidylketone inhibitors of the cysteine protease cathepsin K, BIO MED CH, 7(4), 1999, pp. 581-588
Molecular basis for triclosan activity involves a flipping loop in the active site
Authors: Qiu, XY Janson, CA Court, RI Smyth, MG Payne, DJ Abdel-Meguid, SS
Citation: Xy. Qiu et al., Molecular basis for triclosan activity involves a flipping loop in the active site, PROTEIN SCI, 8(11), 1999, pp. 2529-2532
Crystal structure of beta-ketoacyl-acyl carrier protein synthase III - A key condensing enzyme in bacterial fatty acid biosynthesis
Authors: Qiu, XY Janson, CA Konstantinidis, AK Nwagwu, S Silverman, C Smith, WW Khandekar, S Lonsdale, J Abdel-Meguid, SS
Citation: Xy. Qiu et al., Crystal structure of beta-ketoacyl-acyl carrier protein synthase III - A key condensing enzyme in bacterial fatty acid biosynthesis, J BIOL CHEM, 274(51), 1999, pp. 36465-36471
Cooperative structural dynamics and a novel fidelity mechanism in histidyl-tRNA synthetases
Authors: Qiu, XY Janson, CA Blackburn, MN Chhohan, IK Hibbs, M Abdel-Meguid, SS
Citation: Xy. Qiu et al., Cooperative structural dynamics and a novel fidelity mechanism in histidyl-tRNA synthetases, BIOCHEM, 38(38), 1999, pp. 12296-12304
The crystal structure of human procathepsin K
Authors: LaLonde, JM Zhao, BG Janson, CA D'Alessio, KJ McQueney, MS Orsini, MJ Debouck, CM Smith, WW
Citation: Jm. Lalonde et al., The crystal structure of human procathepsin K, BIOCHEM, 38(3), 1999, pp. 862-869
Risultati: 1-15 |