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Results: 1-20 |
Results: 20
DESIGN AND SELECTION OF DMP-850 AND DMP-851 - THE NEXT-GENERATION OF CYCLIC UREA HIV PROTEASE INHIBITORS (VOL 5, PG 597, 1998)
Authors: RODGERS JD LAM PYS JOHNSON BL WANG HS LI RH RU Y KO SS SEITZ SP TRAINOR GL ANDERSON PS KLABE RM BACHELER LT CORDOVA B GARBER S REID C WRIGHT MR CHANG CH ERICKSONVIITANEN S
Citation: Jd. Rodgers et al., DESIGN AND SELECTION OF DMP-850 AND DMP-851 - THE NEXT-GENERATION OF CYCLIC UREA HIV PROTEASE INHIBITORS (VOL 5, PG 597, 1998), Chemistry & biology, 5(11), 1998, pp. 312-312
DESIGN AND SELECTION OF DMP-850 AND DMP-851 - THE NEXT-GENERATION OF CYCLIC UREA HIV PROTEASE INHIBITORS
Authors: RODGERS JD LAM PYS JOHNSON BL WANG HS KO SS SEITZ SP TRAINOR GL ANDERSON PS KLABE RM BACHELER LT CORDOVA B GARBER S REID C WRIGHT MR CHANG CH ERICKSONVIITANEN S
Citation: Jd. Rodgers et al., DESIGN AND SELECTION OF DMP-850 AND DMP-851 - THE NEXT-GENERATION OF CYCLIC UREA HIV PROTEASE INHIBITORS, Chemistry & biology, 5(10), 1998, pp. 597-608
THE SYNTHESIS OF SYMMETRICAL AND UNSYMMETRICAL P1 P1' CYCLIC UREAS ASHIV PROTEASE INHIBITORS/
Authors: PATEL M KALTENBACH RF NUGIEL DA MCHUGH RJ JADHAV PK BACHELER LT CORDOVA BC KLABE RM ERICKSONVIITANEN S GARBER S REID C SEITZ SP
Citation: M. Patel et al., THE SYNTHESIS OF SYMMETRICAL AND UNSYMMETRICAL P1 P1' CYCLIC UREAS ASHIV PROTEASE INHIBITORS/, Bioorganic & medicinal chemistry letters, 8(9), 1998, pp. 1077-1082
POTENT CYCLIC UREA HIV PROTEASE INHIBITORS WITH 3-AMINOINDAZOLE P2 P2' GROUPS/
Authors: RODGERS JD JOHNSON BL WANG HS ERICKSONVIITANEN S KLABE RM BACHELER L CORDOVA BC CHANG CH
Citation: Jd. Rodgers et al., POTENT CYCLIC UREA HIV PROTEASE INHIBITORS WITH 3-AMINOINDAZOLE P2 P2' GROUPS/, Bioorganic & medicinal chemistry letters, 8(7), 1998, pp. 715-720
THE SYNTHESIS AND EVALUATION OF CYCLIC UREAS AS HIV PROTEASE INHIBITORS - MODIFICATIONS OF THE P1 P1' RESIDUES/
Authors: PATEL M BACHELER LT RAYNER MM CORDOVA BC KLABE RM ERICKSONVIITANEN S SEITZ SP
Citation: M. Patel et al., THE SYNTHESIS AND EVALUATION OF CYCLIC UREAS AS HIV PROTEASE INHIBITORS - MODIFICATIONS OF THE P1 P1' RESIDUES/, Bioorganic & medicinal chemistry letters, 8(7), 1998, pp. 823-828
NONSYMMETRIC P2 P2' CYCLIC UREA HIV PROTEASE INHIBITORS - STRUCTURE-ACTIVITY RELATIONSHIP, BIOAVAILABILITY, AND RESISTANCE PROFILE OF MONOINDAZOLE-SUBSTITUTED P2 ANALOGS/
Authors: DELUCCA GV KIM UT LIANG J CORDOVA B KLABE RM GARBER S BACHELER LT LAM GN WRIGHT MR LOGUE KA ERICKSONVIITANEN S KO SS TRAINOR GL
Citation: Gv. Delucca et al., NONSYMMETRIC P2 P2' CYCLIC UREA HIV PROTEASE INHIBITORS - STRUCTURE-ACTIVITY RELATIONSHIP, BIOAVAILABILITY, AND RESISTANCE PROFILE OF MONOINDAZOLE-SUBSTITUTED P2 ANALOGS/, Journal of medicinal chemistry, 41(13), 1998, pp. 2411-2423
COUNTERACTING HIV-1 PROTEASE DRUG-RESISTANCE - STRUCTURAL-ANALYSIS OFMUTANT PROTEASES COMPLEXED WITH XV638 AND SD146, CYCLIC UREA AMIDES WITH BROAD SPECIFICITIES
Authors: ALA PJ HUSTON EE KLABE RM JADHAV PK LAM PYS CHANG CH
Citation: Pj. Ala et al., COUNTERACTING HIV-1 PROTEASE DRUG-RESISTANCE - STRUCTURAL-ANALYSIS OFMUTANT PROTEASES COMPLEXED WITH XV638 AND SD146, CYCLIC UREA AMIDES WITH BROAD SPECIFICITIES, Biochemistry (Easton), 37(43), 1998, pp. 15042-15049
RESISTANCE TO HIV PROTEASE INHIBITORS - A COMPARISON OF ENZYME-INHIBITION AND ANTIVIRAL POTENCY
Authors: KLABE RM BACHELER LT ALA PJ ERICKSONVIITANEN S MEEK JL
Citation: Rm. Klabe et al., RESISTANCE TO HIV PROTEASE INHIBITORS - A COMPARISON OF ENZYME-INHIBITION AND ANTIVIRAL POTENCY, Biochemistry, 37(24), 1998, pp. 8735-8742
FUNCTIONALIZED ALIPHATIC P2 P2' ANALOGS OF HIV-1 PROTEASE INHIBITOR DMP323/
Authors: SMALLHEER JM MCHUGH RJ CHANG CH KALTENBACH RF WORLEY TV KLABE RM BACHELER LT RAYNER MM ERICKSONVIITANEN S SEITZ SP
Citation: Jm. Smallheer et al., FUNCTIONALIZED ALIPHATIC P2 P2' ANALOGS OF HIV-1 PROTEASE INHIBITOR DMP323/, Bioorganic & medicinal chemistry letters, 7(11), 1997, pp. 1365-1370
MOLECULAR RECOGNITION OF CYCLIC HIV PROTEASE INHIBITORS - NONSYMMETRIC CYCLIC UREAS WITH EXCELLENT ORAL BIOAVAILABILITY AND LOW DRUG-RESISTANCE PROFILES
Authors: LAM PYS RODGERS JD LI R RU Y JADHAV PK CHANG CH CLARK CG SEITZ SP KO SS BACHELER LT KLABE RM LAM GN WRIGHT MR ERICKSONVIITANEN S TRAINOR GL ANDERSON PS
Citation: Pys. Lam et al., MOLECULAR RECOGNITION OF CYCLIC HIV PROTEASE INHIBITORS - NONSYMMETRIC CYCLIC UREAS WITH EXCELLENT ORAL BIOAVAILABILITY AND LOW DRUG-RESISTANCE PROFILES, The FASEB journal, 11(9), 1997, pp. 48-48
DESIGN, SYNTHESIS, AND EVALUATION OF TETRAHYDROPYRIMIDINONES AS AN EXAMPLE OF A GENERAL-APPROACH TO NONPEPTIDE HIV PROTEASE INHIBITORS
Authors: DELUCCA GV LIANG J ALDRICH PE CALABRESE J CORDOVA B KLABE RM RAYNER MM CHANG CH
Citation: Gv. Delucca et al., DESIGN, SYNTHESIS, AND EVALUATION OF TETRAHYDROPYRIMIDINONES AS AN EXAMPLE OF A GENERAL-APPROACH TO NONPEPTIDE HIV PROTEASE INHIBITORS, Journal of medicinal chemistry, 40(11), 1997, pp. 1707-1719
IMPROVED P1 P1' SUBSTITUENTS FOR CYCLIC UREA BASED HIV-1 PROTEASE INHIBITORS - SYNTHESIS, STRUCTURE-ACTIVITY RELATIONSHIP, AND X-RAY CRYSTAL-STRUCTURE ANALYSIS/
Authors: NUGIEL DA JACOBS K CORNELIUS L CHANG CH JADHAV PK HOLLER ER KLABE RM BACHELER LT CORDOVA B GARBER S REID C LOGUE KA GOREYFERET LJ LAM GN ERICKSONVIITANEN S SEITZ SP
Citation: Da. Nugiel et al., IMPROVED P1 P1' SUBSTITUENTS FOR CYCLIC UREA BASED HIV-1 PROTEASE INHIBITORS - SYNTHESIS, STRUCTURE-ACTIVITY RELATIONSHIP, AND X-RAY CRYSTAL-STRUCTURE ANALYSIS/, Journal of medicinal chemistry, 40(10), 1997, pp. 1465-1474
MOLECULAR-BASIS OF HIV-1 PROTEASE DRUG-RESISTANCE - STRUCTURAL-ANALYSIS OF MUTANT PROTEASES COMPLEXED WITH CYCLIC UREA INHIBITORS
Authors: ALA PJ HUSTON EE KLABE RM MCCABE DD DUKE JL RIZZO CJ KORANT BD DELOSKEY RJ LAM PYS HODGE CN CHANG CH
Citation: Pj. Ala et al., MOLECULAR-BASIS OF HIV-1 PROTEASE DRUG-RESISTANCE - STRUCTURAL-ANALYSIS OF MUTANT PROTEASES COMPLEXED WITH CYCLIC UREA INHIBITORS, Biochemistry, 36(7), 1997, pp. 1573-1580
MOLECULAR-BASIS OF HIV-1 PROTEASE DRUG-RESISTANCE - STRUCTURAL-ANALYSIS OF MUTANT PROTEASES COMPLEXED WITH CYCLIC UREA INHIBITORS (VOL 36, PG 1573, 1997)
Authors: ALA PJ HUSTON EE KLABE RM MCCABE DD DUKE JL RIZZO CJ KORANT BD DELOSKEY RJ LAM PYS HODGE CN CHANG CH
Citation: Pj. Ala et al., MOLECULAR-BASIS OF HIV-1 PROTEASE DRUG-RESISTANCE - STRUCTURAL-ANALYSIS OF MUTANT PROTEASES COMPLEXED WITH CYCLIC UREA INHIBITORS (VOL 36, PG 1573, 1997), Biochemistry, 36(21), 1997, pp. 6556-6556
POTENT CYCLIC UREA HIV PROTEASE INHIBITORS WITH BENZOFUSED HETEROCYCLES AS P2 P2' GROUPS/
Authors: RODGERS JD JOHNSON BL WANG HS GREENBERG RA ERICKSONVIITANEN S KLABE RM CORDOVA BC RAYNER MM LAM GN CHANG CH
Citation: Jd. Rodgers et al., POTENT CYCLIC UREA HIV PROTEASE INHIBITORS WITH BENZOFUSED HETEROCYCLES AS P2 P2' GROUPS/, Bioorganic & medicinal chemistry letters, 6(24), 1996, pp. 2919-2924
SYNTHESIS OF (-BIOTIN DERIVATIVES AS HIV-1 PROTEASE INHIBITORS())
Authors: HAN Q LAFONTAINE J BACHELER LT RAYNER MM KLABE RM ERICKSONVIITANEN S LAM PYS
Citation: Q. Han et al., SYNTHESIS OF (-BIOTIN DERIVATIVES AS HIV-1 PROTEASE INHIBITORS()), Bioorganic & medicinal chemistry letters, 6(12), 1996, pp. 1371-1374
CYCLIC HIV PROTEASE INHIBITORS - SYNTHESIS, CONFORMATIONAL-ANALYSIS, P2 P2' STRUCTURE-ACTIVITY RELATIONSHIP, AND MOLECULAR RECOGNITION OF CYCLIC UREAS/
Authors: LAM PYS RU Y JADHAV PK ALDRICH PE DELUCCA GV EYERMANN CJ CHANG CH EMMETT G HOLLER ER DANEKER WF LI LZ CONFALONE PN MCHUGH RJ HAN Q LI RH MARKWALDER JA SEITZ SP SHARPE TR BACHELER LT RAYNER MM KLABE RM SHUM LY WINSLOW DL KORNHAUSER DM JACKSON DA ERICKSONVIITANEN S HODGE CN
Citation: Pys. Lam et al., CYCLIC HIV PROTEASE INHIBITORS - SYNTHESIS, CONFORMATIONAL-ANALYSIS, P2 P2' STRUCTURE-ACTIVITY RELATIONSHIP, AND MOLECULAR RECOGNITION OF CYCLIC UREAS/, Journal of medicinal chemistry, 39(18), 1996, pp. 3514-3525
PREPARATION AND STRUCTURE-ACTIVITY RELATIONSHIP OF NOVEL P1 P1'-SUBSTITUTED CYCLIC UREA-BASED HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 PROTEASE INHIBITORS/
Authors: NUGIEL DA JACOBS K WORLEY T PATEL M KALTENBACH RF MEYER DT JADHAV PK DELUCCA GV SMYSER TE KLABE RM BACHELER LT RAYNER MM SEITZ SP
Citation: Da. Nugiel et al., PREPARATION AND STRUCTURE-ACTIVITY RELATIONSHIP OF NOVEL P1 P1'-SUBSTITUTED CYCLIC UREA-BASED HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 PROTEASE INHIBITORS/, Journal of medicinal chemistry, 39(11), 1996, pp. 2156-2169
A BIS-[N-3-(1-HYDROXY-1-METHYL-ETHYL)-BENZYL)-CYCLIC UREA AS A HIV PROTEASE INHIBITOR
Authors: WILKERSON WW HOLLIS AY CHEATHAM WW LAM GN ERICKSONVIITANEN S BACHELER L CORDOVA BC KLABE RM MEEK JL
Citation: Ww. Wilkerson et al., A BIS-[N-3-(1-HYDROXY-1-METHYL-ETHYL)-BENZYL)-CYCLIC UREA AS A HIV PROTEASE INHIBITOR, Bioorganic & medicinal chemistry letters, 5(24), 1995, pp. 3027-3032
POTENCY AND SELECTIVITY OF INHIBITION OF HUMAN-IMMUNODEFICIENCY-VIRUSPROTEASE BY A SMALL NONPEPTIDE C4 CYCLIC UREA, DMP-323
Authors: ERICKSONVIITANEN S KLABE RM CAWOOD PG ONEAL PL MEEK JL
Citation: S. Ericksonviitanen et al., POTENCY AND SELECTIVITY OF INHIBITION OF HUMAN-IMMUNODEFICIENCY-VIRUSPROTEASE BY A SMALL NONPEPTIDE C4 CYCLIC UREA, DMP-323, Antimicrobial agents and chemotherapy, 38(7), 1994, pp. 1628-1634
Risultati: 1-20 |