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Results: 1-17 |
Results: 17
WHOLE-BODY DISPOSITION AND POLYGLUTAMATE DISTRIBUTION OF THE GAR FORMYLTRANSFERASE INHIBITORS LY309887 AND LOMETREXOL IN MICE - EFFECT OF LOW-FOLATE DIET
Authors: HABECK LL CHAY SH POHLAND RC WORZALLA JF SHIH CA MENDELSOHN LG
Citation: Ll. Habeck et al., WHOLE-BODY DISPOSITION AND POLYGLUTAMATE DISTRIBUTION OF THE GAR FORMYLTRANSFERASE INHIBITORS LY309887 AND LOMETREXOL IN MICE - EFFECT OF LOW-FOLATE DIET, Cancer chemotherapy and pharmacology, 41(3), 1998, pp. 201-209
THE ANTIPROLIFERATIVE AND CELL-CYCLE EFFECTS OF 5,6,7,8-TETRAHYDRO-N-5,N-10-CARBONYLFOLIC ACID, AN INHIBITOR OF METHYLENETETRAHYDROFOLATE DEHYDROGENASE, ARE POTENTIATED BY HYPOXANTHINE
Authors: TONKINSON JL HABECK LL TOTH JE MENDELSOHN LG BEWLEY J SHACKELFORD KA GATES SB RAY J CHEN VJ
Citation: Jl. Tonkinson et al., THE ANTIPROLIFERATIVE AND CELL-CYCLE EFFECTS OF 5,6,7,8-TETRAHYDRO-N-5,N-10-CARBONYLFOLIC ACID, AN INHIBITOR OF METHYLENETETRAHYDROFOLATE DEHYDROGENASE, ARE POTENTIATED BY HYPOXANTHINE, The Journal of pharmacology and experimental therapeutics, 287(1), 1998, pp. 315-321
PRECLINICAL CELLULAR PHARMACOLOGY OF LY231514 (MTA) - A COMPARISON WITH METHOTREXATE, LY309887 AND RALTITREXED FOR THEIR EFFECTS ON INTRACELLULAR FOLATE AND NUCLEOSIDE TRIPHOSPHATE POOLS IN CCRF-CEM CELLS
Authors: CHEN VJ BEWLEY JR ANDIS SL SCHULTZ RM IVERSEN PW SHIH C MENDELSOHN LG SEITZ DE TONKINSON JL
Citation: Vj. Chen et al., PRECLINICAL CELLULAR PHARMACOLOGY OF LY231514 (MTA) - A COMPARISON WITH METHOTREXATE, LY309887 AND RALTITREXED FOR THEIR EFFECTS ON INTRACELLULAR FOLATE AND NUCLEOSIDE TRIPHOSPHATE POOLS IN CCRF-CEM CELLS, British Journal of Cancer, 78, 1998, pp. 27-34
EFFECTS OF MTA (MULTITARGETED ANTIFOLATE, LY231514) ON INTRACELLULAR FOLATE AND NUCLEOSIDE TRIPHOSPHATE POOLS IN CCRF-CEM CELLS
Authors: CHEN VJ BEWLEY JR ANDIS SL SCHULTZ RM SHIH C MENDELSOHN LG SEITZ DE TONKINSON JL
Citation: Vj. Chen et al., EFFECTS OF MTA (MULTITARGETED ANTIFOLATE, LY231514) ON INTRACELLULAR FOLATE AND NUCLEOSIDE TRIPHOSPHATE POOLS IN CCRF-CEM CELLS, European journal of cancer, 33, 1997, pp. 803-803
CELL-CYCLE EFFECTS OF ANTIFOLATE ANTIMETABOLITES - IMPLICATIONS FOR CYTOTOXICITY AND CYTOSTASIS
Authors: TONKINSON JL MARDER P ANDIS SL SCHULTZ RM GOSSETT LS SHIH C MENDELSOHN LG
Citation: Jl. Tonkinson et al., CELL-CYCLE EFFECTS OF ANTIFOLATE ANTIMETABOLITES - IMPLICATIONS FOR CYTOTOXICITY AND CYTOSTASIS, Cancer chemotherapy and pharmacology, 39(6), 1997, pp. 521-531
LY231514, A PYRROLO[2,3-D]PYRIMIDINE-BASED ANTIFOLATE THAT INHIBITS MULTIPLE FOLATE-REQUIRING ENZYMES
Authors: SHIH C CHEN VJ GOSSETT LS GATES SB MACKELLAR WC HABECK LL SHACKELFORD KA MENDELSOHN LG SOOSE DJ PATEL VF ANDIS SL BEWLEY JR RAYL EA MOROSON BA BEARDSLEY GP KOHLER W RATNAM M SCHULTZ RM
Citation: C. Shih et al., LY231514, A PYRROLO[2,3-D]PYRIMIDINE-BASED ANTIFOLATE THAT INHIBITS MULTIPLE FOLATE-REQUIRING ENZYMES, Cancer research, 57(6), 1997, pp. 1116-1123
CHARACTERIZATION OF FOLATE RECEPTOR FROM NORMAL AND NEOPLASTIC MURINETISSUE - INFLUENCE OF DIETARY-FOLATE ON FOLATE RECEPTOR EXPRESSION
Authors: GATES SB MENDELSOHN LG SHACKELFORD KA HABECK LL KURSAR JD GOSSETT LS WORZALLA JF SHIH C GRINDEY GB
Citation: Sb. Gates et al., CHARACTERIZATION OF FOLATE RECEPTOR FROM NORMAL AND NEOPLASTIC MURINETISSUE - INFLUENCE OF DIETARY-FOLATE ON FOLATE RECEPTOR EXPRESSION, Clinical cancer research, 2(7), 1996, pp. 1135-1141
SYNTHESIS AND BIOLOGICAL EVALUATION OF A NEW SERIES OF DIHYDROFOLATE-REDUCTASE INHIBITORS BASED ON THE 4-(2,6-DIAMINO-5-PYRIMIDINYL)ALKYL-L-GLUTAMIC ACID STRUCTURE
Authors: GOSSETT LS HABECK LL GATES SB ANDIS SL WORZALLA JF SCHULTZ RM MENDELSOHN LG KOHLER W RATNAM M GRINDEY GB SHIH CA
Citation: Ls. Gossett et al., SYNTHESIS AND BIOLOGICAL EVALUATION OF A NEW SERIES OF DIHYDROFOLATE-REDUCTASE INHIBITORS BASED ON THE 4-(2,6-DIAMINO-5-PYRIMIDINYL)ALKYL-L-GLUTAMIC ACID STRUCTURE, Bioorganic & medicinal chemistry letters, 6(4), 1996, pp. 473-476
BIOCHEMISTRY AND PHARMACOLOGY OF GLYCINAMIDE RIBONUCLEOTIDE FORMYLTRANSFERASE INHIBITORS - LY309887 AND LOMETREXOL
Authors: MENDELSOHN LG SHIH CA SCHULTZ RM WORZALLA JF
Citation: Lg. Mendelsohn et al., BIOCHEMISTRY AND PHARMACOLOGY OF GLYCINAMIDE RIBONUCLEOTIDE FORMYLTRANSFERASE INHIBITORS - LY309887 AND LOMETREXOL, Investigational new drugs, 14(3), 1996, pp. 287-294
DIETARY-FOLATE AND FOLYLPOLYGLUTAMATE SYNTHETASE-ACTIVITY IN NORMAL AND NEOPLASTIC MURINE TISSUES AND HUMAN TUMOR XENOGRAFTS
Authors: GATES SB WORZALLA JF SHIH C GRINDEY GB MENDELSOHN LG
Citation: Sb. Gates et al., DIETARY-FOLATE AND FOLYLPOLYGLUTAMATE SYNTHETASE-ACTIVITY IN NORMAL AND NEOPLASTIC MURINE TISSUES AND HUMAN TUMOR XENOGRAFTS, Biochemical pharmacology, 52(9), 1996, pp. 1477-1479
ROLE OF MEMBRANE-ASSOCIATED FOLATE BINDING-PROTEIN IN THE CYTOTOXICITY OF ANTIFOLATES IN KB, IGROV1, AND L1210A CELLS
Authors: SCHULTZ RM ANDIS SL SHACKELFORD KA GATES SB RATNAM M MENDELSOHN LG SHIH C GRINDEY GB
Citation: Rm. Schultz et al., ROLE OF MEMBRANE-ASSOCIATED FOLATE BINDING-PROTEIN IN THE CYTOTOXICITY OF ANTIFOLATES IN KB, IGROV1, AND L1210A CELLS, Oncology research, 7(2), 1995, pp. 97-102
SUBSTRATE-SPECIFICITY OF MAMMALIAN FOLYLPOLYGLUTAMATE SYNTHETASE FOR 5,10-DIDEAZATETRAHYDROFOLATE ANALOGS
Authors: HABECK LL MENDELSOHN LG SHIH C TAYLOR EC COLMAN PD GOSSETT LS LEITNER TA SCHULTZ RM ANDIS SL MORAN RG
Citation: Ll. Habeck et al., SUBSTRATE-SPECIFICITY OF MAMMALIAN FOLYLPOLYGLUTAMATE SYNTHETASE FOR 5,10-DIDEAZATETRAHYDROFOLATE ANALOGS, Molecular pharmacology, 48(2), 1995, pp. 326-333
USE OF THE MOUSE VAS-DEFERENS TO DETERMINE MU-RECEPTOR, DELTA-RECEPTOR, AND KAPPA-RECEPTOR AFFINITIES OF OPIOID ANTAGONISTS
Authors: COHEN ML MENDELSOHN LG MITCH CH ZIMMERMAN DM
Citation: Ml. Cohen et al., USE OF THE MOUSE VAS-DEFERENS TO DETERMINE MU-RECEPTOR, DELTA-RECEPTOR, AND KAPPA-RECEPTOR AFFINITIES OF OPIOID ANTAGONISTS, Receptor, 4(1), 1994, pp. 43-53
NOVEL CLASS OF MONOGLUTAMATED ANTIFOLATES EXHIBITS TIGHT-BINDING INHIBITION OF HUMAN GLYCINAMIDE RIBONUCLEOTIDE FORMYLTRANSFERASE AND POTENT ACTIVITY AGAINST SOLID TUMORS
Authors: LEITNER TA SHACKELFORD KA GOSSETT LS SCHULTZ RM ANDIS SL SHIH C GRINDEY GB MENDELSOHN LG
Citation: Ta. Leitner et al., NOVEL CLASS OF MONOGLUTAMATED ANTIFOLATES EXHIBITS TIGHT-BINDING INHIBITION OF HUMAN GLYCINAMIDE RIBONUCLEOTIDE FORMYLTRANSFERASE AND POTENT ACTIVITY AGAINST SOLID TUMORS, Cancer research, 54(4), 1994, pp. 1021-1026
SYNTHESIS AND BIOLOGICAL-ACTIVITY OF 2-DESAMINO AND 4-DEOXY ANALOGS OF 5,10-DIDEAZATETRAHYDROFOLIC ACID (DDATHF)
Authors: SHIH C HU Y GOSSETT LS HABECK LL MENDELSOHN LG GRINDEY GB
Citation: C. Shih et al., SYNTHESIS AND BIOLOGICAL-ACTIVITY OF 2-DESAMINO AND 4-DEOXY ANALOGS OF 5,10-DIDEAZATETRAHYDROFOLIC ACID (DDATHF), Bioorganic & medicinal chemistry letters, 3(12), 1993, pp. 2657-2660
STRUCTURE-ACTIVITY-RELATIONSHIPS OF TRANS-3,4-DIMETHYL-4-(3-HYDROXYPHENYL)PIPERIDINE ANTAGONISTS FOR MU-OPIOID AND KAPPA-OPIOID RECEPTORS
Authors: ZIMMERMAN DM LEANDER JD CANTRELL BE REEL JK SNODDY J MENDELSOHN LG JOHNSON BG MITCH CH
Citation: Dm. Zimmerman et al., STRUCTURE-ACTIVITY-RELATIONSHIPS OF TRANS-3,4-DIMETHYL-4-(3-HYDROXYPHENYL)PIPERIDINE ANTAGONISTS FOR MU-OPIOID AND KAPPA-OPIOID RECEPTORS, Journal of medicinal chemistry, 36(20), 1993, pp. 2833-2841
3,4-DIMETHYL-4-(3-HYDROXYPHENYL)PIPERIDINES - OPIOID ANTAGONISTS WITHPOTENT ANORECTANT ACTIVITY
Authors: MITCH CH LEANDER JD MENDELSOHN LG SHAW WN WONG DT CANTRELL BE JOHNSON BG REEL JK SNODDY JD TAKEMORI AE ZIMMERMAN DM
Citation: Ch. Mitch et al., 3,4-DIMETHYL-4-(3-HYDROXYPHENYL)PIPERIDINES - OPIOID ANTAGONISTS WITHPOTENT ANORECTANT ACTIVITY, Journal of medicinal chemistry, 36(20), 1993, pp. 2842-2850
Risultati: 1-17 |