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Results: 1-25 | 26-31
Results: 1-25/31
STRUCTURE-ACTIVITY-RELATIONSHIPS OF A SERIES OF 1-SUBSTITUTED-4-METHYLBENZIMIDAZOLE NEUROPEPTIDE Y-1 RECEPTOR ANTAGONISTS
Authors: ZIMMERMAN DM CANTRELL BE SMITH ECR NIXON JA BRUNS RF GITTER B HIPSKIND PA ORNSTEIN PL ZARRINMAYEH H BRITTON TC SCHOBER DA GEHLERT DR
Citation: Dm. Zimmerman et al., STRUCTURE-ACTIVITY-RELATIONSHIPS OF A SERIES OF 1-SUBSTITUTED-4-METHYLBENZIMIDAZOLE NEUROPEPTIDE Y-1 RECEPTOR ANTAGONISTS, Bioorganic & medicinal chemistry letters, 8(5), 1998, pp. 473-476
HETEROATOM-SUBSTITUTION AS A STRATEGY FOR INCREASING THE POTENCY OF COMPETITIVE NMDA ANTAGONISTS
Authors: ORNSTEIN PL ARNOLD MB LUNN WHW HEINZ LJ LEANDER JD LODGE D SCHOEPP DD
Citation: Pl. Ornstein et al., HETEROATOM-SUBSTITUTION AS A STRATEGY FOR INCREASING THE POTENCY OF COMPETITIVE NMDA ANTAGONISTS, Bioorganic & medicinal chemistry letters, 8(4), 1998, pp. 389-394
[H-3]LY341495, A HIGHLY POTENT, SELECTIVE AND NOVEL RADIOLIGAND FOR LABELING GROUP-II METABOTROPIC GLUTAMATE RECEPTORS
Authors: ORNSTEIN PL ARNOLD MB BLEISCH TJ WRIGHT RA WHEELER WJ SCHOEPP DD
Citation: Pl. Ornstein et al., [H-3]LY341495, A HIGHLY POTENT, SELECTIVE AND NOVEL RADIOLIGAND FOR LABELING GROUP-II METABOTROPIC GLUTAMATE RECEPTORS, Bioorganic & medicinal chemistry letters, 8(14), 1998, pp. 1919-1922
ACTIONS OF THE POTENT MGLU RECEPTOR ANTAGONIST LY341495 ON HIPPOCAMPAL LTD AND DEPOTENTIATION
Authors: FITZJOHN SM ORNSTEIN PL SCHOEPP DD KINGSTON AE LODGE D COLLINGRIDGE GL
Citation: Sm. Fitzjohn et al., ACTIONS OF THE POTENT MGLU RECEPTOR ANTAGONIST LY341495 ON HIPPOCAMPAL LTD AND DEPOTENTIATION, European journal of neuroscience, 10, 1998, pp. 5418-5418
ACTIONS OF LY341495, A POTENT MGLU RECEPTOR ANTAGONIST, ON HIPPOCAMPAL LTP
Authors: BERTOLOTTO ZA ORNSTEIN PL SCHOEPP DD KINGSTON AE LODGE D COLLINGRIDGE GL
Citation: Za. Bertolotto et al., ACTIONS OF LY341495, A POTENT MGLU RECEPTOR ANTAGONIST, ON HIPPOCAMPAL LTP, European journal of neuroscience, 10, 1998, pp. 9116-9116
DECAHYDROISOQUINOLINES - NOVEL COMPETITIVE AMPA KAINATE ANTAGONISTS WITH NEUROPROTECTIVE EFFECTS IN GLOBAL CEREBRAL-ISCHEMIA/
Authors: ONEILL MJ BOND A ORNSTEIN PL WARD MA HICKS CA HOO K BLEAKMAN D LODGE D
Citation: Mj. Oneill et al., DECAHYDROISOQUINOLINES - NOVEL COMPETITIVE AMPA KAINATE ANTAGONISTS WITH NEUROPROTECTIVE EFFECTS IN GLOBAL CEREBRAL-ISCHEMIA/, Neuropharmacology, 37(10-11), 1998, pp. 1211-1222
THE GLUR5 SUBTYPE OF KAINATE RECEPTOR REGULATES EXCITATORY SYNAPTIC TRANSMISSION IN AREAS CA1 AND CA3 OF THE RAT HIPPOCAMPUS
Authors: VIGNES M CLARKE VRJ PARRY MJ BLEAKMAN D LODGE D ORNSTEIN PL COLLINGRIDGE GL
Citation: M. Vignes et al., THE GLUR5 SUBTYPE OF KAINATE RECEPTOR REGULATES EXCITATORY SYNAPTIC TRANSMISSION IN AREAS CA1 AND CA3 OF THE RAT HIPPOCAMPUS, Neuropharmacology, 37(10-11), 1998, pp. 1269-1277
ACTIONS OF KAINATE AND AMPA SELECTIVE GLUTAMATE-RECEPTOR LIGANDS ON NOCICEPTIVE PROCESSING IN THE SPINAL-CORD
Authors: PROCTER MJ HOUGHTON AK FABER ESL CHIZH BA ORNSTEIN PL LODGE D HEADLEY PM
Citation: Mj. Procter et al., ACTIONS OF KAINATE AND AMPA SELECTIVE GLUTAMATE-RECEPTOR LIGANDS ON NOCICEPTIVE PROCESSING IN THE SPINAL-CORD, Neuropharmacology, 37(10-11), 1998, pp. 1287-1297
LY341495 IS A NANOMOLAR POTENT AND SELECTIVE ANTAGONIST OF GROUP-II METABOTROPIC GLUTAMATE RECEPTORS
Authors: KINGSTON AE ORNSTEIN PL WRIGHT RA JOHNSON BG MAYNE NG BURNETT JP BELAGAJE R WU S SCHOEPP DD
Citation: Ae. Kingston et al., LY341495 IS A NANOMOLAR POTENT AND SELECTIVE ANTAGONIST OF GROUP-II METABOTROPIC GLUTAMATE RECEPTORS, Neuropharmacology, 37(1), 1998, pp. 1-12
KAINATE GLUR5 RECEPTOR SUBTYPE MEDIATES THE NOCICEPTIVE RESPONSE TO FORMALIN IN THE RAT
Authors: SIMMONS RMA LI DL HOO KH DEVERILL M ORNSTEIN PL IYENGAR S
Citation: Rma. Simmons et al., KAINATE GLUR5 RECEPTOR SUBTYPE MEDIATES THE NOCICEPTIVE RESPONSE TO FORMALIN IN THE RAT, Neuropharmacology, 37(1), 1998, pp. 25-36
CURRENT PHARMACOLOGY OF METABOTROPIC GLUTAMATE-RECEPTOR SUBTYPES
Authors: SCHOEPP DD WRIGHT RA JOHNSON BG SALHOFF CR MAYNE NG BURNETT JP WU S MONN JA ORNSTEIN PL
Citation: Dd. Schoepp et al., CURRENT PHARMACOLOGY OF METABOTROPIC GLUTAMATE-RECEPTOR SUBTYPES, Naunyn-Schmiedeberg's archives of pharmacology, 358(1), 1998, pp. 73-73
2-SUBSTITUTED MINO-2-((1SR,2SR)-2-CARBOXYCYCLOPROP-1-YL)GLYCINES AS POTENT AND SELECTIVE ANTAGONISTS OF GROUP-II METABOTROPIC GLUTAMATE RECEPTORS - 1 - EFFECTS OF ALKYL, ARYLALKYL, AND DIARYLALKYL SUBSTITUTION
Authors: ORNSTEIN PL BLEISCH TJ ARNOLD MB WRIGHT RA JOHNSON BG SCHOEPP DD
Citation: Pl. Ornstein et al., 2-SUBSTITUTED MINO-2-((1SR,2SR)-2-CARBOXYCYCLOPROP-1-YL)GLYCINES AS POTENT AND SELECTIVE ANTAGONISTS OF GROUP-II METABOTROPIC GLUTAMATE RECEPTORS - 1 - EFFECTS OF ALKYL, ARYLALKYL, AND DIARYLALKYL SUBSTITUTION, Journal of medicinal chemistry, 41(3), 1998, pp. 346-357
2-SUBSTITUTED MINO-2-((1SR,2SR)-2-CARBOXYCYCLOPROP-1-YL)GLYCINES AS POTENT AND SELECTIVE ANTAGONISTS OF GROUP-II METABOTROPIC GLUTAMATE RECEPTORS - 2 - EFFECTS OF AROMATIC-SUBSTITUTION, PHARMACOLOGICAL CHARACTERIZATION, AND BIOAVAILABILITY
Authors: ORNSTEIN PL BLEISCH TJ ARNOLD MB KENNEDY JH WRIGHT RA JOHNSON BG TIZZANO JP HELTON DR KALLMAN MJ SCHOEPP DD HERIN M
Citation: Pl. Ornstein et al., 2-SUBSTITUTED MINO-2-((1SR,2SR)-2-CARBOXYCYCLOPROP-1-YL)GLYCINES AS POTENT AND SELECTIVE ANTAGONISTS OF GROUP-II METABOTROPIC GLUTAMATE RECEPTORS - 2 - EFFECTS OF AROMATIC-SUBSTITUTION, PHARMACOLOGICAL CHARACTERIZATION, AND BIOAVAILABILITY, Journal of medicinal chemistry, 41(3), 1998, pp. 358-378
SYNTHESIS AND EVALUATION OF A SERIES OF NOVEL 2-[(4-CHLOROPHENOXY)METHYL]BENZIMIDAZOLES AS SELECTIVE NEUROPEPTIDE-Y Y1 RECEPTOR ANTAGONISTS
Authors: ZARRINMAYEH H NUNES AM ORNSTEIN PL ZIMMERMAN DM ARNOLD MB SCHOBER DA GACKENHEIMER SL BRUNS RF HIPSKIND PA BRITTON TC CANTRELL BE GEHLERT DR
Citation: H. Zarrinmayeh et al., SYNTHESIS AND EVALUATION OF A SERIES OF NOVEL 2-[(4-CHLOROPHENOXY)METHYL]BENZIMIDAZOLES AS SELECTIVE NEUROPEPTIDE-Y Y1 RECEPTOR ANTAGONISTS, Journal of medicinal chemistry, 41(15), 1998, pp. 2709-2719
STRUCTURE-ACTIVITY STUDIES OF ARYL-SPACED DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AMPA RECEPTOR ANTAGONISTS
Authors: BLEISCH TJ ORNSTEIN PL ALLEN NK WRIGHT RA LODGE D SCHOEPP DD
Citation: Tj. Bleisch et al., STRUCTURE-ACTIVITY STUDIES OF ARYL-SPACED DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AMPA RECEPTOR ANTAGONISTS, Bioorganic & medicinal chemistry letters, 7(9), 1997, pp. 1161-1166
A HIPPOCAMPAL GLUR5 KAINATE RECEPTOR REGULATING INHIBITORY SYNAPTIC TRANSMISSION
Authors: CLARKE VRJ BALLYK BA HOO KH MANDELZYS A PELLIZZARI A BATH CP THOMAS J SHARPE EF DAVIES CH ORNSTEIN PL SCHOEPP DD KAMBOJ RK COLLINGRIDGE GL LODGE D BLEAKMAN D
Citation: Vrj. Clarke et al., A HIPPOCAMPAL GLUR5 KAINATE RECEPTOR REGULATING INHIBITORY SYNAPTIC TRANSMISSION, Nature, 389(6651), 1997, pp. 599-603
SELECTIVE PROTECTION AGAINST AMPA-EVOKED AND KAINATE-EVOKED NEUROTOXICITY BY ZOLE-5-YL)ETHYL]DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID (LY293558) AND ITS RACEMATE (LY215490)
Authors: SCHOEPP DD SALHOFF CR FUSON KS SACAAN AI TIZZANO JP ORNSTEIN PL MAY PC
Citation: Dd. Schoepp et al., SELECTIVE PROTECTION AGAINST AMPA-EVOKED AND KAINATE-EVOKED NEUROTOXICITY BY ZOLE-5-YL)ETHYL]DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID (LY293558) AND ITS RACEMATE (LY215490), Journal of neural transmission, 103(8-9), 1996, pp. 905-916
PHARMACOLOGICAL DISCRIMINATION OF GLUR5 AND GLUR6 KAINATE RECEPTOR SUBTYPES BY 1(2)H-TETRAZOLE-5-YL)ETHYL]DECAHYDROISOQUINOLINE-3 CARBOXYLIC-ACID
Authors: BLEAKMAN D SCHOEPP DD BALLYK B BUFTON H SHARPE EF THOMAS K ORNSTEIN PL KAMBOJ RK
Citation: D. Bleakman et al., PHARMACOLOGICAL DISCRIMINATION OF GLUR5 AND GLUR6 KAINATE RECEPTOR SUBTYPES BY 1(2)H-TETRAZOLE-5-YL)ETHYL]DECAHYDROISOQUINOLINE-3 CARBOXYLIC-ACID, Molecular pharmacology, 49(4), 1996, pp. 581-585
DISCRIMINATION OF GLUR5 AND GLUR6 IONOTROPIC GLUTAMATE RECEPTOR-MEDIATED RESPONSES BY LY293558 ON SINGLE CELLS IN-VITRO
Authors: BLEAKMAN D SCHOEPP DD LODGE D ORNSTEIN PL BUFTON H SHARPE EF THOMAS K BALLYK B KAMBOJ R
Citation: D. Bleakman et al., DISCRIMINATION OF GLUR5 AND GLUR6 IONOTROPIC GLUTAMATE RECEPTOR-MEDIATED RESPONSES BY LY293558 ON SINGLE CELLS IN-VITRO, Journal of physiology, 493P, 1996, pp. 51-51
STRUCTURE-ACTIVITY STUDIES OF 6-(TETRAZOLYLALKYL)-SUBSTITUTED DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AMPA RECEPTOR ANTAGONISTS .1. EFFECTSOF STEREOCHEMISTRY, CHAIN-LENGTH, AND CHAIN SUBSTITUTION
Authors: ORNSTEIN PL ARNOLD MB ALLEN NK BLEISCH T BORROMEO PS LUGAR CW LEANDER JD LODGE D SCHOEPP DD
Citation: Pl. Ornstein et al., STRUCTURE-ACTIVITY STUDIES OF 6-(TETRAZOLYLALKYL)-SUBSTITUTED DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AMPA RECEPTOR ANTAGONISTS .1. EFFECTSOF STEREOCHEMISTRY, CHAIN-LENGTH, AND CHAIN SUBSTITUTION, Journal of medicinal chemistry, 39(11), 1996, pp. 2219-2231
STRUCTURE-ACTIVITY STUDIES OF 6-SUBSTITUTED DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AMPA RECEPTOR ANTAGONISTS .2. EFFECTS OF DISTAL ACID BIOISOSTERIC SUBSTITUTION, ABSOLUTE STEREOCHEMICAL PREFERENCES, AND IN-VIVO ACTIVITY
Authors: ORNSTEIN PL ARNOLD MB ALLEN NK BLEISCH T BORROMEO PS LUGAR CW LEANDER JD LODGE D SCHOEPP DD
Citation: Pl. Ornstein et al., STRUCTURE-ACTIVITY STUDIES OF 6-SUBSTITUTED DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AMPA RECEPTOR ANTAGONISTS .2. EFFECTS OF DISTAL ACID BIOISOSTERIC SUBSTITUTION, ABSOLUTE STEREOCHEMICAL PREFERENCES, AND IN-VIVO ACTIVITY, Journal of medicinal chemistry, 39(11), 1996, pp. 2232-2244
IN-VITRO AND IN-VIVO ANTAGONISM OF AMPA RECEPTOR ACTIVATION BY ZOLE-5-YL)ETHYL]DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID
Authors: SCHOEPP DD LODGE D BLEAKMAN D LEANDER JD TIZZANO JP WRIGHT RA PALMER AJ SALHOFF CR ORNSTEIN PL
Citation: Dd. Schoepp et al., IN-VITRO AND IN-VIVO ANTAGONISM OF AMPA RECEPTOR ACTIVATION BY ZOLE-5-YL)ETHYL]DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID, Neuropharmacology, 34(9), 1995, pp. 1159-1168
SCHEDULE-CONTROLLED BEHAVIORAL-EFFECTS OF THE SELECTIVE AMINO-3-(5-METHYL-3-HYDROXYISOXAZOL-4-YL)PROPANOIC ACID ANTAGONIST LY293558 IN PIGEONS
Authors: BENVENGA MJ ORNSTEIN PL LEANDER JD
Citation: Mj. Benvenga et al., SCHEDULE-CONTROLLED BEHAVIORAL-EFFECTS OF THE SELECTIVE AMINO-3-(5-METHYL-3-HYDROXYISOXAZOL-4-YL)PROPANOIC ACID ANTAGONIST LY293558 IN PIGEONS, The Journal of pharmacology and experimental therapeutics, 275(1), 1995, pp. 164-170
CYCLOTHIAZIDE ACTS AT A SITE ON THE ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLE PROPIONIC-ACID RECEPTOR COMPLEX THAT DOES NOT RECOGNIZE COMPETITIVE OR NONCOMPETITIVE AMPA RECEPTOR ANTAGONISTS
Authors: DESAI MA BURNETT JP ORNSTEIN PL SCHOEPP DD
Citation: Ma. Desai et al., CYCLOTHIAZIDE ACTS AT A SITE ON THE ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLE PROPIONIC-ACID RECEPTOR COMPLEX THAT DOES NOT RECOGNIZE COMPETITIVE OR NONCOMPETITIVE AMPA RECEPTOR ANTAGONISTS, The Journal of pharmacology and experimental therapeutics, 272(1), 1995, pp. 38-43
H-TETRAZOL-5-YL)DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID, A NOVEL, COMPETITIVE, SYSTEMICALLY ACTIVE NMDA AND AMPA RECEPTOR ANTAGONIST
Authors: ORNSTEIN PL ARNOLD MB ALLEN NK LEANDER JD TIZZANO JP LODGE D SCHOEPP DD
Citation: Pl. Ornstein et al., H-TETRAZOL-5-YL)DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID, A NOVEL, COMPETITIVE, SYSTEMICALLY ACTIVE NMDA AND AMPA RECEPTOR ANTAGONIST, Journal of medicinal chemistry, 38(25), 1995, pp. 4885-4890
Risultati: 1-25 | 26-31