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Results: 1-18 |
Results: 18
Oligonucleotides and their analogues - Preface
Authors: Torrence, PF
Citation: Pf. Torrence, Oligonucleotides and their analogues - Preface, CURR MED CH, 8(10), 2001, pp. NIL_2-NIL_2
Chemistry and biochemistry of 2 ',5 '-oligoadenylate-based antisense strategy
Authors: Adah, SA Bayly, SF Cramer, H Silverman, RH Torrence, PF
Citation: Sa. Adah et al., Chemistry and biochemistry of 2 ',5 '-oligoadenylate-based antisense strategy, CURR MED CH, 8(10), 2001, pp. 1189-1212
Accelerating RNA decay through intervention of RNase L: Alternative synthesis of composite 2 ',5 '-oligoadenylate-antisense
Authors: Torrence, PF Wang, ZF
Citation: Pf. Torrence et Zf. Wang, Accelerating RNA decay through intervention of RNase L: Alternative synthesis of composite 2 ',5 '-oligoadenylate-antisense, METH ENZYM, 342, 2001, pp. 20-28
Synthesis and RNase L binding and activation of a 2-5A-(5 ')-DNA-(3 ')-PNAchimera, a novel potential antisense molecule
Authors: Verheijen, JC Chen, L Bayly, SF Torrence, PF van der Marel, GA van Boom, JH
Citation: Jc. Verheijen et al., Synthesis and RNase L binding and activation of a 2-5A-(5 ')-DNA-(3 ')-PNAchimera, a novel potential antisense molecule, NUCLEOS NUC, 19(10-12), 2000, pp. 1821-1830
Replacement of the phosphodiester linkage in DNA with sulfamide and 3 '-N-sulfamate groups
Authors: Fettes, KJ Howard, N Hickman, DT Adah, SA Player, MR Torrence, PF Micklefield, J
Citation: Kj. Fettes et al., Replacement of the phosphodiester linkage in DNA with sulfamide and 3 '-N-sulfamate groups, CHEM COMMUN, (9), 2000, pp. 765-766
Fluorescence resonance energy transfer analysis of RNase L-catalyzed oligonucleotide cleavage
Authors: Geselowitz, DA Cramer, H Wondrak, EM Player, MR Torrence, PF
Citation: Da. Geselowitz et al., Fluorescence resonance energy transfer analysis of RNase L-catalyzed oligonucleotide cleavage, ANTISENSE N, 10(1), 2000, pp. 45-51
Incorporation of a 4-hydroxy-N-acetylprolinol nucleotide analogue improvesthe 3 '-exonuclease stability of 2 '-5 '-oligoadenylate-antisense conjugates
Authors: Verheijen, JC van Roon, AMM Meeuwenoord, NJ Stuivenberg, HR Bayly, SF Chen, L van der Marel, GA Torrence, PF van Boom, JH
Citation: Jc. Verheijen et al., Incorporation of a 4-hydroxy-N-acetylprolinol nucleotide analogue improvesthe 3 '-exonuclease stability of 2 '-5 '-oligoadenylate-antisense conjugates, BIOORG MED, 10(8), 2000, pp. 801-804
2-methyladenosine-substituted 2 ',5 '-oligoadenylates: Conformations, 2-5Abinding and catalytic activities with human ribonuclease L
Authors: Kitade, Y Wakana, M Tsuboi, T Yatome, C Bayly, SF Player, MR Torrence, PF
Citation: Y. Kitade et al., 2-methyladenosine-substituted 2 ',5 '-oligoadenylates: Conformations, 2-5Abinding and catalytic activities with human ribonuclease L, BIOORG MED, 10(4), 2000, pp. 329-331
Convergent synthesis of ribonuclease L-active 2 ',5 '- oligoadenylate-peptide nucleic acids
Authors: Wang, ZF Chen, L Bayly, SF Torrence, PF
Citation: Zf. Wang et al., Convergent synthesis of ribonuclease L-active 2 ',5 '- oligoadenylate-peptide nucleic acids, BIOORG MED, 10(12), 2000, pp. 1357-1360
Selective RNA cleavage by isolated RNase L activated with 2-5A antisense chimeric oligonucleotides
Authors: Silverman, RH Dong, BH Maitra, RK Player, MR Torrence, PF
Citation: Rh. Silverman et al., Selective RNA cleavage by isolated RNase L activated with 2-5A antisense chimeric oligonucleotides, METH ENZYM, 313, 2000, pp. 522-533
Abstracts from the Third Annual NIH Symposium on Therapeutic Oligonucleotides: Discovery and Milestone Achievements - December 4, 1998 - Bethesda, Maryland
Authors: Cho-Chung, YS Beaucag, S Marquez, V Neckers, L Torrence, PF
Citation: Ys. Cho-chung et al., Abstracts from the Third Annual NIH Symposium on Therapeutic Oligonucleotides: Discovery and Milestone Achievements - December 4, 1998 - Bethesda, Maryland, ANTISENSE N, 9(4), 1999, pp. 359-359
2 ',5 '-oligoadenylate-antisense chimeras as experimental therapeutic agents for cancer and viral infections
Authors: Silverman, RH Cowell, JK Torrence, PF
Citation: Rh. Silverman et al., 2 ',5 '-oligoadenylate-antisense chimeras as experimental therapeutic agents for cancer and viral infections, ANTISENSE N, 9(4), 1999, pp. 409-414
2 ',5 '-oligoadenylate-peptide nucleic acids (2-5A-PNAs) activate RNase L
Authors: Verheijen, JC van der Marel, GA van Boom, JH Bayly, SF Player, MR Torrence, PF
Citation: Jc. Verheijen et al., 2 ',5 '-oligoadenylate-peptide nucleic acids (2-5A-PNAs) activate RNase L, BIO MED CH, 7(3), 1999, pp. 449-455
Discrimination between ribonuclease H- and ribonuclease L-mediated RNA degradation by 2 '-O-methylated 2-5A-antisense oligonucleotides
Authors: Cramer, H Player, MR Torrence, PF
Citation: H. Cramer et al., Discrimination between ribonuclease H- and ribonuclease L-mediated RNA degradation by 2 '-O-methylated 2-5A-antisense oligonucleotides, BIOORG MED, 9(7), 1999, pp. 1049-1054
Phosphorothioate oligodeoxyribonucleotides inhibit ribonuclease L thereby disabling a mechanism of interferon action.
Authors: Player, MR Torrence, PF
Citation: Mr. Player et Pf. Torrence, Phosphorothioate oligodeoxyribonucleotides inhibit ribonuclease L thereby disabling a mechanism of interferon action., BIOORG MED, 9(6), 1999, pp. 891-894
2-5A-PNA complexes: A novel class of antisense compounds
Authors: Verheijen, JC Bayly, SF Player, MR Torrence, PF van der Marel, GA van Boom, JH
Citation: Jc. Verheijen et al., 2-5A-PNA complexes: A novel class of antisense compounds, NUCLEOS NUC, 18(6-7), 1999, pp. 1485-1486
Using fluorescence resonance energy transfer (FRET) for measuring 2-5A analogues ability to activate RNase L
Authors: Cramer, H Geselowitz, DA Torrence, PF
Citation: H. Cramer et al., Using fluorescence resonance energy transfer (FRET) for measuring 2-5A analogues ability to activate RNase L, NUCLEOS NUC, 18(6-7), 1999, pp. 1523-1525
2-5A-DNA conjugate inhibition of respiratory syncytial virus replication: effects of oligonucleotide structure modifications and RNA target site selection
Authors: Barnard, DL Sidwell, RW Xiao, W Player, MR Adah, SA Torrence, PF
Citation: Dl. Barnard et al., 2-5A-DNA conjugate inhibition of respiratory syncytial virus replication: effects of oligonucleotide structure modifications and RNA target site selection, ANTIVIR RES, 41(3), 1999, pp. 119-134
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