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Results: 1-17 |
Results: 17
INTERACTION OF A NOVEL GDP EXCHANGE INHIBITOR WITH THE RAS PROTEIN
Authors: GANGULY AK WANG YS PRAMANIK BN DOLL RJ SNOW ME TAVERAS AG REMISZEWSKI S CESARZ D DELROSARIO J VIBULBHAN B BROWN JE KIRSCHMEIER P HUANG EC HEIMARK L TSARBOPOULOS A GIRIJAVALLABHAN VM AUST RM BROWN EL DELISLE DM FUHRMAN SA HENDRICKSON TF KISSINGER CR LOVE RA SISSON WA VILLAFRANCA JE WEBBER SE
Citation: Ak. Ganguly et al., INTERACTION OF A NOVEL GDP EXCHANGE INHIBITOR WITH THE RAS PROTEIN, Biochemistry (Easton), 37(45), 1998, pp. 15631-15637
STRUCTURE-BASED DESIGN OF NOVEL CALCINEURIN (PP2B) INHIBITORS
Authors: TATLOCK JH LINTON MA HOU XJ KISSINGER CR PELLETIER LA SHOWALTER RE TEMPCZYK A VILLAFRANCA JE
Citation: Jh. Tatlock et al., STRUCTURE-BASED DESIGN OF NOVEL CALCINEURIN (PP2B) INHIBITORS, Bioorganic & medicinal chemistry letters, 7(8), 1997, pp. 1007-1012
FROM HERESY TO SUPERSTITION - THE POWER AND LIMITS OF STRUCTURE-BASEDDRUG DESIGN
Authors: VILLAFRANCA JE
Citation: Je. Villafranca, FROM HERESY TO SUPERSTITION - THE POWER AND LIMITS OF STRUCTURE-BASEDDRUG DESIGN, The FASEB journal, 11(9), 1997, pp. 47-47
KINETIC SCHEME FOR THYMIDYLATE SYNTHASE FROM ESCHERICHIA-COLI - DETERMINATION FROM MEASUREMENTS OF LIGAND-BINDING, PRIMARY AND SECONDARY ISOTOPE EFFECTS, AND PRE-STEADY-STATE CATALYSIS
Authors: SPENCER HT VILLAFRANCA JE APPLEMAN JR
Citation: Ht. Spencer et al., KINETIC SCHEME FOR THYMIDYLATE SYNTHASE FROM ESCHERICHIA-COLI - DETERMINATION FROM MEASUREMENTS OF LIGAND-BINDING, PRIMARY AND SECONDARY ISOTOPE EFFECTS, AND PRE-STEADY-STATE CATALYSIS, Biochemistry, 36(14), 1997, pp. 4212-4222
STRUCTURE-BASED DESIGN OF NOVEL, UREA-CONTAINING FKBP12 INHIBITORS
Authors: DRAGOVICH PS BARKER JE FRENCH J IMBACUAN M KALISH VJ KISSINGER CR KNIGHTON DR LEWIS CT MOOMAW EW PARGE HE PELLETIER LAK PRINS TJ SHOWALTER RE TATLOCK JH TUCKER KD VILLAFRANCA JE
Citation: Ps. Dragovich et al., STRUCTURE-BASED DESIGN OF NOVEL, UREA-CONTAINING FKBP12 INHIBITORS, Journal of medicinal chemistry, 39(9), 1996, pp. 1872-1884
STRUCTURE-BASED DESIGN OF LIPOPHILIC QUINAZOLINE INHIBITORS OF THYMIDYLATE SYNTHASE
Authors: JONES TR VARNEY MD WEBBER SE LEWIS KK MARZONI GP PALMER CL KATHARDEKAR V WELSH KM WEBBER S MATTHEWS DA APPELT K SMITH WW JANSON CA VILLAFRANCA JE BACQUET RJ HOWLAND EF BOOTH CLJ HERRMANN SM WARD RW WHITE J MOOMAW EW BARTLETT CA MORSE CA
Citation: Tr. Jones et al., STRUCTURE-BASED DESIGN OF LIPOPHILIC QUINAZOLINE INHIBITORS OF THYMIDYLATE SYNTHASE, Journal of medicinal chemistry, 39(4), 1996, pp. 904-917
HIGH-AFFINITY FKBP-12 LIGANDS DERIVED FROM (R)-(-)-CARVONE - SYNTHESIS AND EVALUATION OF PK506 PYRANOSE RING REPLACEMENTS
Authors: TATLOCK JH KALISH VJ PARGE HE KNIGHTON DR SHOWALTER RE LEWIS CT FRENCH JV VILLAFRANCA JE
Citation: Jh. Tatlock et al., HIGH-AFFINITY FKBP-12 LIGANDS DERIVED FROM (R)-(-)-CARVONE - SYNTHESIS AND EVALUATION OF PK506 PYRANOSE RING REPLACEMENTS, Bioorganic & medicinal chemistry letters, 5(21), 1995, pp. 2489-2494
DESIGN, SYNTHESIS AND X-RAY CRYSTALLOGRAPHIC STUDIES OF NOVEL FKBP-12LIGANDS
Authors: BABINE RE BLECKMAN TM KISSINGER CR SHOWALTER R PELLETIER LA LEWIS C TUCKER K MOOMAW E PARGE HE VILLAFRANCA JE
Citation: Re. Babine et al., DESIGN, SYNTHESIS AND X-RAY CRYSTALLOGRAPHIC STUDIES OF NOVEL FKBP-12LIGANDS, Bioorganic & medicinal chemistry letters, 5(15), 1995, pp. 1719-1724
CHARACTERIZATION OF HUMAN RECOMBINANT CALCINEURIN HETERODIMER COEXPRESSED IN BACTERIA AND INSECT CELLS
Authors: LEWIS C GASTINEL L HABUKA N TUCKER K CHEN XH MALDONADO F VILLAFRANCA JE
Citation: C. Lewis et al., CHARACTERIZATION OF HUMAN RECOMBINANT CALCINEURIN HETERODIMER COEXPRESSED IN BACTERIA AND INSECT CELLS, The FASEB journal, 9(6), 1995, pp. 1346-1346
EMPIRICAL FREE-ENERGY CALCULATIONS OF LIGAND-PROTEIN CRYSTALLOGRAPHICCOMPLEXES .1. KNOWLEDGE-BASED LIGAND-PROTEIN INTERACTION POTENTIALS APPLIED TO THE PREDICTION OF HUMAN-IMMUNODEFICIENCY-VIRUS-1 PROTEASE BINDING-AFFINITY
Authors: VERKHIVKER G APPELT K FREER ST VILLAFRANCA JE
Citation: G. Verkhivker et al., EMPIRICAL FREE-ENERGY CALCULATIONS OF LIGAND-PROTEIN CRYSTALLOGRAPHICCOMPLEXES .1. KNOWLEDGE-BASED LIGAND-PROTEIN INTERACTION POTENTIALS APPLIED TO THE PREDICTION OF HUMAN-IMMUNODEFICIENCY-VIRUS-1 PROTEASE BINDING-AFFINITY, Protein engineering, 8(7), 1995, pp. 677-691
CRYSTAL-STRUCTURES OF HUMAN CALCINEURIN AND THE HUMAN FKBP12-FK506-CALCINEURIN COMPLEX
Authors: KISSINGER CR PARGE HE KNIGHTON DR LEWIS CT PELLETIER LA TEMPCZYK A KALISH VJ TUCKER KD SHOWALTER RE MOOMAW EW GASTINEL LN HABUKA N CHEN XH MALDONADO F BARKER JE BACQUET R VILLAFRANCA JE
Citation: Cr. Kissinger et al., CRYSTAL-STRUCTURES OF HUMAN CALCINEURIN AND THE HUMAN FKBP12-FK506-CALCINEURIN COMPLEX, Nature, 378(6557), 1995, pp. 641-644
STEREOELECTRONIC ACTIVATION OF METHYLENETETRAHYDROFOLATE BY THYMIDYLATE SYNTHASE - RESONANCE RAMAN-SPECTROSCOPIC EVIDENCE
Authors: AUSTIN JC FITZHUGH A VILLAFRANCA JE SPIRO TG
Citation: Jc. Austin et al., STEREOELECTRONIC ACTIVATION OF METHYLENETETRAHYDROFOLATE BY THYMIDYLATE SYNTHASE - RESONANCE RAMAN-SPECTROSCOPIC EVIDENCE, Biochemistry, 34(23), 1995, pp. 7678-7685
RESONANCE RAMAN CHARACTERIZATION OF THE BINARY AND TERNARY COMPLEXES OF THYMIDYLATE SYNTHASE WITH 5-NITRODEOXYURIDYLATE
Authors: AUSTIN JC LEPAR FH VILLAFRANCA JE SPIRO TG
Citation: Jc. Austin et al., RESONANCE RAMAN CHARACTERIZATION OF THE BINARY AND TERNARY COMPLEXES OF THYMIDYLATE SYNTHASE WITH 5-NITRODEOXYURIDYLATE, Biochemistry, 34(23), 1995, pp. 7686-7693
CRYSTAL-STRUCTURE OF HUMAN RHINOVIRUS TYPE-14 3C-PROTEASE
Authors: MATTHEWS D SMITH WW FERRE RA CONDON B BUDAHAZI G SISSON W VILLAFRANCA JE JANSON C MCELROY H GRIBSKOV C WORLAND S
Citation: D. Matthews et al., CRYSTAL-STRUCTURE OF HUMAN RHINOVIRUS TYPE-14 3C-PROTEASE, Journal of cellular biochemistry, 1994, pp. 170-170
STRUCTURE OF HUMAN RHINOVIRUS 3C PROTEASE REVEALS A TRYPSIN-LIKE POLYPEPTIDE FOLD, RNA-BINDING SITE, AND MEANS FOR CLEAVING PRECURSOR POLYPROTEIN
Authors: MATTHEWS DA SMITH WW FERRE RA CONDON B BUDAHAZI G SISSON W VILLAFRANCA JE JANSON CA MCELROY HE GRIBSKOV CL WORLAND S
Citation: Da. Matthews et al., STRUCTURE OF HUMAN RHINOVIRUS 3C PROTEASE REVEALS A TRYPSIN-LIKE POLYPEPTIDE FOLD, RNA-BINDING SITE, AND MEANS FOR CLEAVING PRECURSOR POLYPROTEIN, Cell, 77(5), 1994, pp. 761-771
HOW THE ANTI-(METAL CHELATE) ANTIBODY CHA255 IS SPECIFIC FOR THE METAL-ION OF ITS ANTIGEN - X-RAY STRUCTURES FOR 2 FAB' HAPTEN COMPLEXES WITH DIFFERENT METALS IN THE CHELATE
Authors: LOVE RA VILLAFRANCA JE AUST RM NAKAMURA KK JUE RA MAJOR JG RADHAKRISHNAN R BUTLER WF
Citation: Ra. Love et al., HOW THE ANTI-(METAL CHELATE) ANTIBODY CHA255 IS SPECIFIC FOR THE METAL-ION OF ITS ANTIGEN - X-RAY STRUCTURES FOR 2 FAB' HAPTEN COMPLEXES WITH DIFFERENT METALS IN THE CHELATE, Biochemistry, 32(41), 1993, pp. 10950-10959
SUBSTITUTION OF GLUTAMINE FOR GLUTAMIC ACID-58 IN ESCHERICHIA-COLI THYMIDYLATE SYNTHASE RESULTS IN PRONOUNCED DECREASES IN CATALYTIC ACTIVITY AND LIGAND-BINDING
Authors: ZAPF JW WEIR MS EMERICK V VILLAFRANCA JE DUNLAP RB
Citation: Jw. Zapf et al., SUBSTITUTION OF GLUTAMINE FOR GLUTAMIC ACID-58 IN ESCHERICHIA-COLI THYMIDYLATE SYNTHASE RESULTS IN PRONOUNCED DECREASES IN CATALYTIC ACTIVITY AND LIGAND-BINDING, Biochemistry, 32(36), 1993, pp. 9274-9281
Risultati: 1-17 |