Authors:
GOULET MT
MCALPINE SR
STARUCH MJ
KOPRAK S
DUMONT FJ
CRYAN JG
WIEDERRECHT GJ
ROSA R
WILUSZ MB
PETERSON LB
WYVRATT MJ
PARSONS WH
Citation: Mt. Goulet et al., C32-O-IMIDAZOL-2-YL-METHYL ETHER DERIVATIVES OF THE IMMUNOSUPPRESSANTASCOMYCIN WITH IMPROVED THERAPEUTIC POTENTIAL, Bioorganic & medicinal chemistry letters, 8(16), 1998, pp. 2253-2258
Authors:
DUMONT FJ
KOPRAK S
STARUCH MJ
TALENTO A
KOO G
DASILVA C
SINCLAIR PJ
WONG F
WOODS J
BARKER J
PIVNICHNY J
SINGER I
SIGAL NH
WILLIAMSON AR
PARSONS WH
WYVRATT M
Citation: Fj. Dumont et al., A TACROLIMUS-RELATED IMMUNOSUPPRESSANT WITH REDUCED TOXICITY, Transplantation, 65(1), 1998, pp. 18-26
Authors:
DUMONT FJ
STARUCH MJ
FISCHER P
DASILVA C
CAMACHO R
Citation: Fj. Dumont et al., INHIBITION OF T-CELL ACTIVATION BY PHARMACOLOGICAL DISRUPTION OF THE MEK1 ERK MAP KINASE OR CALCINEURIN SIGNALING PATHWAYS RESULTS IN DIFFERENTIAL MODULATION OF CYTOKINE PRODUCTION/, The Journal of immunology, 160(6), 1998, pp. 2579-2589
Citation: Fj. Dumont, FK506 ENHANCES IL-13 PRODUCTION BY T-CELLS ACTIVATED THROUGH CD3 CD28/, International archives of allergy and immunology, 114(3), 1997, pp. 300-301
Authors:
OK HO
SZUMILOSKI JL
BEATTIE TR
GOULET MT
STARUCH MJ
DUMONT FJ
WYVRATT MJ
Citation: Ho. Ok et al., C32-AMINO DERIVATIVES OF THE IMMUNOSUPPRESSANT ASCOMYCIN, Bioorganic & medicinal chemistry letters, 7(17), 1997, pp. 2199-2204
Authors:
STARUCH MJ
SU OX
DASILVA C
FISCHER P
DUMONT FJ
Citation: Mj. Staruch et al., ISOLATION OF T-CELL MUTANTS WITH ALTERED CALCIUM SIGNALING, Journal of allergy and clinical immunology, 99(1), 1997, pp. 847-847
Authors:
SHAFIEE A
MOTAMEDI H
DUMONT FJ
ARISON BH
MILLER RR
Citation: A. Shafiee et al., CHEMICAL AND BIOLOGICAL CHARACTERIZATION OF 2 FK506 ANALOGS PRODUCED BY TARGETED GENE DISRUPTION IN STREPTOMYCES SP MA6548, Journal of antibiotics, 50(5), 1997, pp. 418-423
Citation: Fj. Dumont et O. Su, CALCINEURIN DOWN-REGULATES IL-1-INDUCED INTERFERON-GAMMA (IFN-GAMMA) PRODUCTION, The FASEB journal, 10(6), 1996, pp. 942-942
Citation: S. Koprak et al., DEPLETION OF THE MATURE CD4(-) THYMOCYTE SUBSET BY FK506 ANALOGS CORRELATES WITH THEIR IMMUNOSUPPRESSIVE AND CALCINEURIN INHIBITORY ACTIVITIES()8(), Transplantation, 61(6), 1996, pp. 926-932
Authors:
DUMONT FJ
OK H
LIN S
KASTNER CA
CRYAN J
MARTIN MM
WIEDERRECHT G
STARUCH MJ
Citation: Fj. Dumont et al., MIXED AGONIST-ANTAGONIST ACTIVITY OF AN FK-506-RELATED IMMUNOSUPPRESSANT - BIOLOGICAL AND BIOCHEMICAL-CHARACTERIZATION, The Journal of pharmacology and experimental therapeutics, 276(3), 1996, pp. 1078-1088
Citation: Qx. Su et al., CYCLOSPORINE-A ENHANCES THE CALCIUM-DEPENDENT INDUCTION OF AP-1 COMPLEX AND C-FOS MESSENGER-RNA IN A T-CELL LYMPHOMA, Biochemical and biophysical research communications, 229(1), 1996, pp. 249-256
Authors:
SALITURO GM
ZINK DL
DAHL A
NIELSEN J
WU E
HUANG LY
KASTNER C
DUMONT FJ
Citation: Gm. Salituro et al., MERIDAMYCIN - A NOVEL NONIMMUNOSUPPRESSIVE FKBP12 LIGAND FROM STREPTOMYCES-HYGROSCOPICUS, Tetrahedron letters, 36(7), 1995, pp. 997-1000
Authors:
SABERS CJ
MARTIN MM
BRUNN GJ
WILLIAMS JM
DUMONT FJ
WIEDERRECHT G
ABRAHAM RT
Citation: Cj. Sabers et al., ISOLATION OF A PROTEIN TARGET OF THE FKBP12-RAPAMYCIN COMPLEX IN MAMMALIAN-CELLS, The Journal of biological chemistry, 270(2), 1995, pp. 815-822
Citation: Fj. Dumont et al., INCREASED LFA-1-MEDIATED HOMOTYPIC CELL-ADHESION IS ASSOCIATED WITH THE G(1) GROWTH ARREST INDUCED BY RAPAMYCIN IN A T-CELL LYMPHOMA, Experimental cell research, 219(1), 1995, pp. 146-158
Authors:
DUMONT FJ
STARUCH MJ
GRAMMER T
BLENIS J
KASTNER CA
RUPPRECHT KM
Citation: Fj. Dumont et al., DOMINANT MUTATIONS CONFER RESISTANCE TO THE IMMUNOSUPPRESSANT, RAPAMYCIN, IN VARIANTS OF A T-CELL LYMPHOMA, Cellular immunology, 163(1), 1995, pp. 70-79
Authors:
PETUCH BR
ARISON B
HSU A
MONAGHAN R
DUMONT FJ
CHEN TS
Citation: Br. Petuch et al., MICROBIAL TRANSFORMATION OF IMMUNOSUPPRESSIVE COMPOUNDS .3. GLUCOSYLATION OF IMMUNOMYCIN (FR-900520) AND FK-506 BY BACILLUS-SUBTILIS ATCC-55060, Journal of industrial microbiology, 13(2), 1994, pp. 131-135
Authors:
DUMONT FJ
KASTNER C
IACOVONE F
FISCHER PA
Citation: Fj. Dumont et al., QUANTITATIVE AND TEMPORAL ANALYSIS OF THE CELLULAR INTERACTION OF FK-506 AND RAPAMYCIN IN T-LYMPHOCYTES, The Journal of pharmacology and experimental therapeutics, 268(1), 1994, pp. 32-41
Authors:
DUMONT FJ
ALTMEYER A
KASTNER C
FISCHER PA
LEMON KP
CHUNG JK
BLENIS J
STARUCH MJ
Citation: Fj. Dumont et al., RELATIONSHIP BETWEEN MULTIPLE BIOLOGIC EFFECTS OF RAPAMYCIN AND THE INHIBITION OF PP70S6 PROTEIN-KINASE ACTIVITY - ANALYSIS IN MUTANT CLONES OF A T-CELL LYMPHOMA, The Journal of immunology, 152(3), 1994, pp. 992-1003
Citation: Fj. Dumont et Ca. Kastner, TRANSFORMING GROWTH-FACTOR BETA(1) INHIBITS INTERLEUKIN-1-INDUCED BUTENHANCES IONOMYCIN-INDUCED INTERFERON-GAMMA PRODUCTION IN A T-CELL LYMPHOMA - COMPARISON WITH THE EFFECTS OF RAPAMYCIN, Journal of cellular physiology, 160(1), 1994, pp. 141-153
Citation: A. Altmeyer et Fj. Dumont, RAPAMYCIN INHIBITS IL-1-MEDIATED INTERFERON-GAMMA PRODUCTION IN THE YAC-1 T-CELL LYMPHOMA, Cytokine, 5(2), 1993, pp. 133-143
Authors:
SHAFIEE A
CHEN TS
ARISON BS
DUMONT FJ
COLWELL L
KAPLAN L
Citation: A. Shafiee et al., ENZYMATIC-SYNTHESIS AND IMMUNOSUPPRESSIVE ACTIVITY OF NOVEL DESMETYLATED IMMUNOMYCINS (ASCOMYCINS), Journal of antibiotics, 46(9), 1993, pp. 1397-1405