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Results: 1-25 | 26-50 | 51-72
Results: 1-25/72
Design of new mononucleotide prodrugs: Aryl (SATE) phosphotriester derivatives
Authors: Peyrottes, S Schlienger, N Beltran, T Lefebvre, I Pompon, A Gosselin, G Aubertin, AM Imbach, JL Perigaud, C
Citation: S. Peyrottes et al., Design of new mononucleotide prodrugs: Aryl (SATE) phosphotriester derivatives, NUCLEOS NUC, 20(4-7), 2001, pp. 315-321
Anti-HBV specific beta-L-2 '-deoxynucleosides
Authors: Bryant, ML Bridges, EG Placidi, L Faraj, A Loi, AG Pierra, C Dukhan, D Gosselin, G Imbach, JL Hernandez, B Juodawlkis, A Tennant, B Korba, B Cote, P Cretton-Scott, E Schinazi, RF Sommadossi, JP
Citation: Ml. Bryant et al., Anti-HBV specific beta-L-2 '-deoxynucleosides, NUCLEOS NUC, 20(4-7), 2001, pp. 597-607
Synthesis and study of a new series of phosphoramidate derivatives as mononucleotide prodrugs
Authors: Egron, D Perigaud, C Gosselin, G Aubertin, AM Imbach, JL
Citation: D. Egron et al., Synthesis and study of a new series of phosphoramidate derivatives as mononucleotide prodrugs, NUCLEOS NUC, 20(4-7), 2001, pp. 751-754
Synthesis and antiviral evaluation of 3 '-C-trifluoromethyl nucleoside derivatives bearing adenine as the base
Authors: Jeannot, F Mathe, C Gosselin, G
Citation: F. Jeannot et al., Synthesis and antiviral evaluation of 3 '-C-trifluoromethyl nucleoside derivatives bearing adenine as the base, NUCLEOS NUC, 20(4-7), 2001, pp. 755-758
Unnatural enantiomers of 5-azacytidine analogues: Syntheses and enzymatic properties
Authors: Gaubert, G Gosselin, G Eriksson, S Vita, A Maury, G
Citation: G. Gaubert et al., Unnatural enantiomers of 5-azacytidine analogues: Syntheses and enzymatic properties, NUCLEOS NUC, 20(4-7), 2001, pp. 837-840
Simultaneous HPLC analysis of hydrophobic prodrugs and their hydrophilic metabolites in biological media without sample preparation. Application to the biotransformation studies of pronucleotides derived from 5-fluorouracil
Authors: Coussot, G Lefebvre-Tournier, I Hollecker, L Gosselin, G Imbach, JL Pompon, A
Citation: G. Coussot et al., Simultaneous HPLC analysis of hydrophobic prodrugs and their hydrophilic metabolites in biological media without sample preparation. Application to the biotransformation studies of pronucleotides derived from 5-fluorouracil, NUCLEOS NUC, 20(4-7), 2001, pp. 855-858
Synthesis and antiviral evaluation of C-4-hydrazide derivatives of 2 ',3 '-dideoxycytidine
Authors: Boudou-Vivet, V Mathe, C Gosselin, G
Citation: V. Boudou-vivet et al., Synthesis and antiviral evaluation of C-4-hydrazide derivatives of 2 ',3 '-dideoxycytidine, NUCLEOS NUC, 20(4-7), 2001, pp. 1029-1032
Synthesis and in vitro activity of D- and L-enantiomers of 5-(trifluoromethyl)uracil nucleoside derivatives
Authors: Salvetti, R Pregnolato, M Verri, A Focher, F Spadari, S Marchand, A Mathe, C Gosselin, G
Citation: R. Salvetti et al., Synthesis and in vitro activity of D- and L-enantiomers of 5-(trifluoromethyl)uracil nucleoside derivatives, NUCLEOS NUC, 20(4-7), 2001, pp. 1123-1125
Complications of cardiac catheterization in the current era: A single-center experience
Authors: Chandrasekar, B Doucet, S Bilodeau, L Crepeau, J deGuise, P Gregoire, J Gallo, R Cote, G Bonan, R Joyal, M Gosselin, G Tanguay, JF Dyrda, I Bois, M Pasternac, A
Citation: B. Chandrasekar et al., Complications of cardiac catheterization in the current era: A single-center experience, CATHET C IN, 52(3), 2001, pp. 289-295
5-(trifluoromethyl)-beta-L-2 '-deoxyuridine, the L-enantiomer of trifluorothymidine: Stereospecific synthesis and antiherpetic evaluations
Authors: Salvetti, R Marchand, A Pregnolato, M Verri, A Spadari, S Focher, F Briant, M Sommadossi, JP Mathe, C Gosselin, G
Citation: R. Salvetti et al., 5-(trifluoromethyl)-beta-L-2 '-deoxyuridine, the L-enantiomer of trifluorothymidine: Stereospecific synthesis and antiherpetic evaluations, BIO MED CH, 9(7), 2001, pp. 1731-1738
Rational design of a new series of pronucleotide
Authors: Beltran, T Egron, D Pompon, A Lefebvre, I Perigaud, C Gosselin, G Aubertin, AM Imbach, JL
Citation: T. Beltran et al., Rational design of a new series of pronucleotide, BIOORG MED, 11(13), 2001, pp. 1775-1777
Impact of residual plaque burden after balloon angioplasty in the MultiVitamins and Probucol (MVP) trial
Authors: Tardif, JC Cote, G Lesperance, J Gosselin, G Joyal, M de Guise, P Bilodeau, L Doucet, S Harel, F Couturier, A Gallo, R Gregoire, J
Citation: Jc. Tardif et al., Impact of residual plaque burden after balloon angioplasty in the MultiVitamins and Probucol (MVP) trial, CAN J CARD, 17(1), 2001, pp. 49-55
Stereospecific synthesis and biological evaluations of beta-L-pentofuranonucleoside derivatives of 5-fluorouracil and 5-fluorocytosine
Authors: Griffon, JF Mathe, C Faraj, A Aubertin, AM De Clercq, E Balzarini, J Sommadossi, JP Gosselin, G
Citation: Jf. Griffon et al., Stereospecific synthesis and biological evaluations of beta-L-pentofuranonucleoside derivatives of 5-fluorouracil and 5-fluorocytosine, EUR J MED C, 36(5), 2001, pp. 447-460
Evaluation of the mutagenic and genotoxic activities of anti-hepatitis B analogs of beta-L-adenosine by the Ames test and the Comet assay
Authors: Placidi, L De Meo, M Gosselin, G Imbach, JL Bryant, ML Dumenil, G Sommadossi, JP
Citation: L. Placidi et al., Evaluation of the mutagenic and genotoxic activities of anti-hepatitis B analogs of beta-L-adenosine by the Ames test and the Comet assay, ANTIVIR RES, 50(2), 2001, pp. 139-145
Maedi-visna virus, a model for in vitro testing of potential anti-HIV drugs
Authors: Salvatori, D Vincenzetti, S Maury, G Gosselin, G Gaubert, G Vita, A
Citation: D. Salvatori et al., Maedi-visna virus, a model for in vitro testing of potential anti-HIV drugs, COMPAR IMM, 24(2), 2001, pp. 113-122
Potentiation of inhibition of wild-type and mutant human immunodeficiency virus type 1 reverse transcriptases by combinations of nonnucleoside inhibitors and D- and L-(beta)-dideoxynucleoside triphosphate analogs
Authors: Maga, C Hubscher, U Pregnolato, M Ubiali, D Gosselin, G Spadari, S
Citation: C. Maga et al., Potentiation of inhibition of wild-type and mutant human immunodeficiency virus type 1 reverse transcriptases by combinations of nonnucleoside inhibitors and D- and L-(beta)-dideoxynucleoside triphosphate analogs, ANTIM AG CH, 45(4), 2001, pp. 1192-1200
Antiviral L-nucleosides specific for hepatitis B virus infection
Authors: Bryant, ML Bridges, EG Placidi, L Faraj, A Loi, AG Pierra, C Dukhan, D Gosselin, G Imbach, JL Hernandez, B Juodawlkis, A Tennant, B Korba, B Cote, P Marion, P Cretton-Scott, E Schinazi, RF Sommadossi, JP
Citation: Ml. Bryant et al., Antiviral L-nucleosides specific for hepatitis B virus infection, ANTIM AG CH, 45(1), 2001, pp. 229-235
Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation.
Authors: Yusuf, S Fox, KAA Tognoni, G Mehta, SR Chrolavicius, S Anand, S Avezum, A Awan, N Bertrand, M Budaj, A Ceremuzynski, L Col, J Commerford, PJ Diaz, R Flather, M Franzosi, MG Gersh, B Grossman, W Halon, DA Hunt, D Joyner, C Karatzas, N Keltai, M Kopecky, S Lewis, BS Maggioni, A Malmberg, K Moccetti, T Morais, J Natarajan, M Paolasso, E Peters, R Piegas, L Pipilis, A Pogue, J Ramos-Corrales, M Rupprecht, HJ Sitkei, E Valentin, V Varigos, J Widimsky, P Wittlinger, T Blumenthal, M Bouthier, J Gaudin, C Hess, T Khurmi, N Sotty, M Copland, I Cracknell, B Demers, C Eikelboom, J Morris, B Pasquale, J Yacyshyn, V Zhao, F Wyse, G Cairns, J Hart, R Hirsh, J Gent, M Ryan, T Wittes, J Guerrero, RA Arias, V Bello, FH Bono, JO Bujan, L Caccavo, A Fernandez, AA Fuselli, JJ Gambarte, AJ Hasbani, EG Marzetti, E Mon, G Nordaby, R Quijano, G Salvati, A San Martin, E Schygiel, P Liprandi, AS Torre, H Tuero, E Amerena, J Bett, JHN Botha, J Buncle, A Careless, D Ewart, A Fagan, A Fitzpatrick, D Garrahy, P Gunawardane, K Hamer, A Hill, A Jepson, N Lane, G LeGood, H Nelson, G Sallaberger, M Tulloch, G Owensby, D Padley, J Rees, D Roberts, K Rosen, D Sampson, J Singh, B Singh, C Taylor, R Thomson, A Walsh, W De Raedt, H Rankin, J Abrantes, JA de Albuquerque, DC Blacher, C Bodanese, LC Carvalho, AC Coutinho, M Dutra, O Esteves, JP Leaes, P Lima, NS Lobo, N Neto, JAM Marino, RL Nicolau, JC Pedrosa, RC Pereira, I Rabelo, W Rabelo, A Ramos, RF Rocha, RM Schramm, EC Serrano, CV Souza, VP Timerman, A Vaz, R Xavier, SS Auger, P Barbin, K Bata, I Bergeron, L Bhargava, RK Bogaty, P Bolduc, P Boyne, T Boyer, L Bozek, B Calmusky, T Chan, YK Cole, D D'Astous, M David, M Davies, T Desjardins, L Dohaney, PB Doody, M Dumont, F Fortin, C Fung, A Galdreault, G Gervais, PB Giannoccaro, JP Gosselin, G Grandmont, D Grover, A Gupta, M Hink, H Hiscock, JG Hutton, D Hynd, JWH Iless, A Kent, C Kitching, A Kouz, S Kwok, K LaForest, M Lee, H Lefkowitz, C Lubelsky, B Ma, P Marquis, JF McCallum, A Major, R May, B Mercier, M Montigny, M Morris, A Nawaz, S Norris, J Pallie, S Panju, A Parekh, P Patterson, C Pesant, Y Pilon, C Rajakumar, ARJ Rebane, T Ricci, J Ruel, M Schuld, R Starra, R Thornley, M Weeks, AS Winkler, LH Wisenberg, G Witt, I Woo, K Yu, E Zadra, R Zaniol, D Bocek, P Branny, M Cepelak, V Gregor, P Groch, L Jansky, P Svitil, P Vaclavicek, A Husted, S Ziegler, B Karhu, A Mustonen, J Nieminen, M Nissinen, K Peuhkurinen, K Tuomainen, P Ylitalo, A Adam, M Amat, G Asward, K Bessede, G Dambrine, P Decoulx, E D'Hautefeuille, B Dujardin, J Fouche, R Fournier, P Haftel, Y Ketelers, JY Lallemant, R Lang, M Leroy, F Richard, M Dippold, W Gronholz, J Harenberg, J Hilpert, C Horacek, T Moritz, A Neuss, H Nitsche, K Ochs, HR Plumer-Schmidt, M Pollock, B Post, G Sauer, M Schmidt, A Schmitt, H Schulze, HO Schuster, P von Leitner, ER Christakos, S Karidis, K Kifnidis, K Papadopoulos, K Symconidis, D Tirologos, A Garai, B Gesztesi, T Heltai, K Herczeg, B Janosi, A Kadar, A Kalo, E Karpati, P Kiss, B Nagy, A Okros, M Poor, F Regos, L Sebo, J Sitkei, E Soltesz, P Stefan, J Szaboki, F Timar, S Varallyay, Z Veres, K Daly, K Cotter, G Marmor, A Nazzal, D Omary, M Reisin, L Rosenfeld, T Shargorodsky, M Shasha, S Smulovitz, A Vered, Z Zimlichman, R Beria, G Bernardi, D Bonfanti, E Ceci, V De Caterina, R De Servi, S DelPinto, M Di Chiara, A Di Pasquale, G Filippucci, L Galli, M Gardinale, E Landoni, MT Martoni, A Mauri, F Maurea, N Meneghetti, P Mennuni, M Murrone, A Pani, A Paolini, E Passarelli, P Pettinati, G Pontillo, B Rossi, L Rossi, R Santini, M Sabino, G Tricoci, P Turazza, FM Diaz, AC Garcia-Sosa, A Santamaria, IH Pons, JL Medecigo, JN Rojo, FJR Diaz, CJS Castro, JT Morales, EV Baldew, S Basart, DCG Bijsterfeld, N Bronzwaer, P Chardon, A den Hartoog, M Heijmen, H Heijmeriks, J Jochemsen, G Klomps, H Landsaat, P Michels, H Moons, A Pieterse, M Sadee, A van Beek, G Van Hessen, M Verheul, J Viergever, E Audeau, M Hills, M Ikram, H Johnstone, M Smart, A Erikssen, J Morstel, T Winther, J Achremczyk, P Baranowska, A Burduk, P Cichon, D Czepiel, A Danielewicz, H Danielewicz, P Dworzanski, W Gessek, J Gorecki, A Gorny, J Janik, K Jedrzejowski, A Kania, G Kawka-Urbanek, T Klaudel, J Kopcik, D Kozlowski, A Krasowski, W Ladach, A Laniec, M Maciejewicz, J Maciejewski, P Majcher, Z Malinowski, S Marczyk, T Miekus, P Myczka, T Ogorek, M Piepiorka, M Religa, K Reszka, Z Rozwodowska, M Smielak-Korombel, W Smiglak, D Spyra, J Stec, S Susol, D Szpajer, M Szymanski, P Szymcyyk-Muszytowska, G Tomzynski, M Ujda, M Wasek, W Waszyrowski, T Wojewoda, P Wnorowska, A Wrobel, P Zadrozny, J Zebrowski, A Zielinski, Z Bastos, JM Cardoso, P Carrageta, M Catarino, C Ferreira, R Gomes, MV Aboo, A Bobak, L Brown, B Cassim, S Harripersadh, S Manga, P Maritz, F Marx, J Myburgh, D Nell, H Okreglicki, A Theron, H Orcajo, NA Colomina, F Echanove, I Guerrer, JG Gomez-Martinez, E Lekuona, I Miralles, L Pasaval, C Rovira, A San Jose, J Llorian, AR Valentin, V Abdon, N Bartholdson, B Basilier, E Johansson, I Kristensson, B Larsson, K Lindell, P Moller, B Rasmanis, G Stjerna, A Tolhagen, K Caduff, B Noseda, G Rossi, A Schmidt, D Zerega, J Carr, K Detrano, R Geer, R Grewal, G Hermany, P Lakkis, N Lewis, WR Pacheco, TR Papuchis, G Puma, J Runckey, S Thadani, U Whitaker, J Adgey, YJA Blackman, D Brack, M Bridges, A Cohen, A Currie, P Duffy, S Findlay, I Goodfellow, J Gray, K Hogg, D Holdright, D Hughes, D Irvine, N Jennings, K Keeling, P Ludman, P Mathew, T McIntyre, P Oliver, R Palmer, N Rodrigues, E Smyth, L Sprigings, D Stephens, J Timmis, A Vincent, R
Citation: S. Yusuf et al., Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation., N ENG J MED, 345(7), 2001, pp. 494-502
New bis(SATE) prodrug of AZT 5 '-monophosphate: In vitro anti-HIV activity, stability, and potential oral absorption
Authors: Shafiee, M Deferme, S Villard, AL Egron, D Gosselin, G Imbach, JL Lioux, T Pompon, A Varray, S Aubertin, AM Van den Mooter, G Kinget, R Perigaud, C Augustijns, P
Citation: M. Shafiee et al., New bis(SATE) prodrug of AZT 5 '-monophosphate: In vitro anti-HIV activity, stability, and potential oral absorption, J PHARM SCI, 90(4), 2001, pp. 448-463
Hepatitis C virus NS3NTPase/helicase: Different stereoselectivity in nucleoside triphosphate utilisation suggests that NTPase and helicase activitiesare coupled by a nucleotide-dependent rate limiting step
Authors: Locatelli, GA Gosselin, G Spadari, S Maga, G
Citation: Ga. Locatelli et al., Hepatitis C virus NS3NTPase/helicase: Different stereoselectivity in nucleoside triphosphate utilisation suggests that NTPase and helicase activitiesare coupled by a nucleotide-dependent rate limiting step, J MOL BIOL, 313(4), 2001, pp. 683-694
Synthesis and antiviral evaluation of unnatural beta-L-enantiomers of 3 '-fluoro- and 3 '-azido-2 ',3 '-dideoxyguanosine derivatives
Authors: Marchand, A Mathe, C Imbach, JL Gosselin, G
Citation: A. Marchand et al., Synthesis and antiviral evaluation of unnatural beta-L-enantiomers of 3 '-fluoro- and 3 '-azido-2 ',3 '-dideoxyguanosine derivatives, NUCLEOS NUC, 19(1-2), 2000, pp. 205-217
In vitro and in vivo metabolism and pharmacokinetics of bis [(T-butyl)-S-acyl-2-thioethyl]-beta-1-2 ',3 '-dideoxy-5-fluorocytidine monophosphate
Authors: Martin, LT Cretton-Scott, E Placidi, L Faraj, A Loi, AG Schinazi, RF McClure, HM Gosselin, G Imbach, JL Sommadossi, JP
Citation: Lt. Martin et al., In vitro and in vivo metabolism and pharmacokinetics of bis [(T-butyl)-S-acyl-2-thioethyl]-beta-1-2 ',3 '-dideoxy-5-fluorocytidine monophosphate, NUCLEOS NUC, 19(1-2), 2000, pp. 481-499
Synthesis and antiviral evaluation of the beta-L-enantiomers of some thymine 3 '-deoxypentofuranonucleoside derivatives
Authors: Mathe, C Gosselin, G
Citation: C. Mathe et G. Gosselin, Synthesis and antiviral evaluation of the beta-L-enantiomers of some thymine 3 '-deoxypentofuranonucleoside derivatives, NUCLEOS NUC, 19(10-12), 2000, pp. 1517-1530
Left main stenting - as a bridge to surgery - for acute type A aortic dissection and anterior myocardial infarction
Authors: Barabas, M Gosselin, G Crepeau, J Petitclerc, R Cartier, R Theroux, P
Citation: M. Barabas et al., Left main stenting - as a bridge to surgery - for acute type A aortic dissection and anterior myocardial infarction, CATHET C IN, 51(1), 2000, pp. 74-77
Pharmacokinetics of bis(t-butyl-SATE)-AZTMP, a bispivaloylthioethyl prodrug for intracellular delivery of zidovudine monophosphate, in mice
Authors: Tan, XL Boudinot, FD Chu, CK Egron, D Perigaud, C Gosselin, G Imbach, JL
Citation: Xl. Tan et al., Pharmacokinetics of bis(t-butyl-SATE)-AZTMP, a bispivaloylthioethyl prodrug for intracellular delivery of zidovudine monophosphate, in mice, ANTIVIR CHE, 11(3), 2000, pp. 203-211
Risultati: 1-25 | 26-50 | 51-72